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{
{
   "id": "https://openalex.org/T11440",
   "OpenAlex": {
  "display_name": "Click Chemistry in Chemical Biology and Drug Development",
    "cited_by_count": 935274,
  "description": "This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.",
    "created_date": "2024-01-23",
  "keywords": [
    "description": "This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.",
    "Click Chemistry",
    "display_name": "Click Chemistry in Chemical Biology and Drug Development",
    "Copper-Catalyzed Cycloaddition",
     "domain": {
    "Bioorthogonal Chemistry",
      "id": "https://openalex.org/domains/3",
    "Azides and Alkynes",
      "display_name": "Physical Sciences"
    "Chemical Functionality",
    "Drug Discovery",
     "Protein Labeling",
    "In Vivo Imaging",
    "Triazole Synthesis",
    "Enzyme Inhibitors"
  ],
  "ids": {
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    "wikipedia": "https://en.wikipedia.org/wiki/Click_chemistry"
  },
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    "id": "https://openalex.org/subfields/1605",
    "display_name": "Organic Chemistry"
  },
  "field": {
    "id": "https://openalex.org/fields/16",
    "display_name": "Chemistry"
  },
  "domain": {
    "id": "https://openalex.org/domains/3",
    "display_name": "Physical Sciences"
  },
  "siblings": [
    {
      "id": "https://openalex.org/T12570",
      "display_name": "Advances in Photoinitiated Polymerization Reactions"
     },
     },
     {
     "field": {
       "id": "https://openalex.org/T13649",
       "id": "https://openalex.org/fields/16",
       "display_name": "Amide Chemistry and Synthesis"
       "display_name": "Chemistry"
     },
     },
     {
     "id": "https://openalex.org/T11440",
       "id": "https://openalex.org/T10701",
    "ids": {
       "display_name": "Applications of Photoredox Catalysis in Organic Synthesis"
       "openalex": "https://openalex.org/T11440",
       "wikipedia": "https://en.wikipedia.org/wiki/Click_chemistry"
     },
     },
     {
     "keywords": [
       "id": "https://openalex.org/T11298",
      "Click Chemistry",
      "display_name": "Aromaticity in Organic Molecules and Materials"
      "Copper-Catalyzed Cycloaddition",
      "Bioorthogonal Chemistry",
      "Azides and Alkynes",
      "Chemical Functionality",
      "Drug Discovery",
      "Protein Labeling",
      "In Vivo Imaging",
      "Triazole Synthesis",
      "Enzyme Inhibitors"
    ],
    "siblings": [
      {
        "id": "https://openalex.org/T12570",
        "display_name": "Advances in Photoinitiated Polymerization Reactions"
      },
       {
        "id": "https://openalex.org/T13649",
        "display_name": "Amide Chemistry and Synthesis"
      },
      {
        "id": "https://openalex.org/T10701",
        "display_name": "Applications of Photoredox Catalysis in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T11298",
        "display_name": "Aromaticity in Organic Molecules and Materials"
      },
      {
        "id": "https://openalex.org/T12653",
        "display_name": "Aryne Chemistry in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T10013",
        "display_name": "Asymmetric Catalysis"
      },
      {
        "id": "https://openalex.org/T13115",
        "display_name": "Atroposelective Synthesis of Axially Chiral Compounds"
      },
      {
        "id": "https://openalex.org/T13833",
        "display_name": "Bioorganometallic Chemistry of Ferrocene Derivatives"
      },
      {
        "id": "https://openalex.org/T12251",
        "display_name": "Catalytic C-H Amination Reactions"
      },
      {
        "id": "https://openalex.org/T11611",
        "display_name": "Catalytic Carbene Chemistry in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T11989",
        "display_name": "Catalytic Oxidation of Alcohols"
      },
      {
        "id": "https://openalex.org/T12240",
        "display_name": "Catalytic Reduction of Nitro Compounds"
      },
      {
        "id": "https://openalex.org/T14297",
        "display_name": "Chemical Composition and Bioactivity of Maple Syrup"
      },
      {
        "id": "https://openalex.org/T13568",
        "display_name": "Chemical Constituents and Production of Agarwood"
      },
      {
        "id": "https://openalex.org/T10835",
        "display_name": "Chemical Glycobiology and Therapeutic Applications"
      },
      {
        "id": "https://openalex.org/T12526",
        "display_name": "Chemistry and Applications of Antimicrobial Polymers"
      },
      {
        "id": "https://openalex.org/T10956",
        "display_name": "Chemistry and Applications of Fullerenes"
      },
      {
        "id": "https://openalex.org/T11748",
        "display_name": "Chemistry and Applications of Phosphonates"
      },
      {
        "id": "https://openalex.org/T13265",
        "display_name": "Chemistry and Applications of Tetrazoles"
      },
      {
        "id": "https://openalex.org/T12458",
        "display_name": "Chemistry and Biological Activities of Organotin Compounds"
      },
      {
        "id": "https://openalex.org/T10909",
        "display_name": "Chemistry and Health Effects of Olive Oil"
      },
      {
        "id": "https://openalex.org/T13124",
        "display_name": "Chemistry and Pharmacology of Amaryllidaceae Alkaloids"
      },
      {
        "id": "https://openalex.org/T12318",
        "display_name": "Chemistry and Pharmacology of Quinazoline Compounds"
      },
      {
        "id": "https://openalex.org/T13105",
        "display_name": "Chemistry of Pyrrolobenzodiazepines"
      },
      {
        "id": "https://openalex.org/T12973",
        "display_name": "Chemistry of Quinone Methides"
      },
      {
        "id": "https://openalex.org/T11441",
        "display_name": "Frustrated Lewis Pairs Chemistry"
      },
      {
        "id": "https://openalex.org/T10871",
        "display_name": "Gold Catalysis in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T12410",
        "display_name": "Heterocyclic Chemistry Synthesis"
      },
      {
        "id": "https://openalex.org/T10274",
        "display_name": "Heterocyclic Compounds for Drug Discovery"
      },
      {
        "id": "https://openalex.org/T13230",
        "display_name": "Indolizine Synthesis and Bioactivity Studies"
      },
      {
        "id": "https://openalex.org/T11831",
        "display_name": "Innovations in Organic Synthesis Reactions"
      },
      {
        "id": "https://openalex.org/T10405",
        "display_name": "Living Radical Polymerization"
      },
      {
        "id": "https://openalex.org/T13239",
        "display_name": "Mechanism and Applications of Wittig Reaction"
      },
      {
        "id": "https://openalex.org/T12270",
        "display_name": "Microwave-Assisted Chemistry in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T10817",
        "display_name": "Multicomponent Reactions"
      },
      {
        "id": "https://openalex.org/T11790",
        "display_name": "N-Heterocyclic Carbenes in Catalysis and Materials Chemistry"
      },
      {
        "id": "https://openalex.org/T12191",
        "display_name": "Nucleophilic Reactivity in Organic Chemistry"
      },
      {
        "id": "https://openalex.org/T11549",
        "display_name": "Olefin Metathesis Chemistry"
      },
      {
        "id": "https://openalex.org/T11746",
        "display_name": "Organic Chemistry and Catalysis"
      },
      {
        "id": "https://openalex.org/T12228",
        "display_name": "Organometallic Chemistry and Metalation"
      },
      {
        "id": "https://openalex.org/T14318",
        "display_name": "Polydiacetylene Supramolecular Chemosensors"
      },
      {
        "id": "https://openalex.org/T13013",
        "display_name": "Predicting Antioxidant Activity of Phenolic Compounds"
      },
      {
        "id": "https://openalex.org/T12527",
        "display_name": "Principles of Stereochemical Structure and Nomenclature"
      },
      {
        "id": "https://openalex.org/T12562",
        "display_name": "Pyrrole Synthesis and Applications"
      },
      {
        "id": "https://openalex.org/T14099",
        "display_name": "Recent Advances in Triazine Chemistry"
      },
      {
        "id": "https://openalex.org/T13208",
        "display_name": "Recent Developments in Ketene Dithioacetal Chemistry"
      },
      {
        "id": "https://openalex.org/T13859",
        "display_name": "Recent Developments in Organic Synthesis"
      },
      {
        "id": "https://openalex.org/T10578",
        "display_name": "Self-Assembly and Molecular Recognition in Chemistry"
      },
      {
        "id": "https://openalex.org/T10721",
        "display_name": "Surfactant Aggregation and Self-Assembly Phenomena"
      },
      {
        "id": "https://openalex.org/T13304",
        "display_name": "Synthesis and Applications of Thioamides"
      },
      {
        "id": "https://openalex.org/T13489",
        "display_name": "Synthesis and Applications of \u00df-Lactams"
      },
      {
        "id": "https://openalex.org/T14459",
        "display_name": "Synthesis and Biological Activities of Oxazolones"
      },
      {
        "id": "https://openalex.org/T13160",
        "display_name": "Synthesis and Biological Activities of Quinoxaline Derivatives"
      },
      {
        "id": "https://openalex.org/T13876",
        "display_name": "Synthesis and Properties of Heterocyclic Compounds"
      },
      {
        "id": "https://openalex.org/T12852",
        "display_name": "Thermochemical Properties of Organic Compounds"
      },
      {
        "id": "https://openalex.org/T10092",
        "display_name": "Transition Metal Catalysis"
      },
      {
        "id": "https://openalex.org/T10548",
        "display_name": "Transition Metal-Catalyzed Cross-Coupling Reactions"
      },
      {
        "id": "https://openalex.org/T10354",
        "display_name": "Transition-Metal-Catalyzed C\u2013H Bond Functionalization"
      },
      {
        "id": "https://openalex.org/T12189",
        "display_name": "Transition-Metal-Catalyzed Sulfur Chemistry"
      },
      {
        "id": "https://openalex.org/T12893",
        "display_name": "Understanding Reactivity in Organic Reactions"
      }
    ],
    "subfield": {
      "id": "https://openalex.org/subfields/1605",
      "display_name": "Organic Chemistry"
     },
     },
     {
     "updated_date": "2024-08-19T06:05:47.176779",
      "id": "https://openalex.org/T12653",
     "works_count": 39775,
      "display_name": "Aryne Chemistry in Organic Synthesis"
     "oa_id": "T11440"
    },
  }
    {
      "id": "https://openalex.org/T10013",
      "display_name": "Asymmetric Catalysis"
    },
    {
      "id": "https://openalex.org/T13115",
      "display_name": "Atroposelective Synthesis of Axially Chiral Compounds"
    },
    {
      "id": "https://openalex.org/T13833",
      "display_name": "Bioorganometallic Chemistry of Ferrocene Derivatives"
    },
    {
      "id": "https://openalex.org/T12251",
      "display_name": "Catalytic C-H Amination Reactions"
    },
    {
      "id": "https://openalex.org/T11611",
      "display_name": "Catalytic Carbene Chemistry in Organic Synthesis"
    },
    {
      "id": "https://openalex.org/T11989",
      "display_name": "Catalytic Oxidation of Alcohols"
    },
    {
      "id": "https://openalex.org/T12240",
      "display_name": "Catalytic Reduction of Nitro Compounds"
    },
    {
      "id": "https://openalex.org/T14297",
      "display_name": "Chemical Composition and Bioactivity of Maple Syrup"
    },
    {
      "id": "https://openalex.org/T13568",
      "display_name": "Chemical Constituents and Production of Agarwood"
    },
    {
      "id": "https://openalex.org/T10835",
      "display_name": "Chemical Glycobiology and Therapeutic Applications"
    },
    {
      "id": "https://openalex.org/T12526",
      "display_name": "Chemistry and Applications of Antimicrobial Polymers"
    },
    {
      "id": "https://openalex.org/T10956",
      "display_name": "Chemistry and Applications of Fullerenes"
    },
    {
      "id": "https://openalex.org/T11748",
      "display_name": "Chemistry and Applications of Phosphonates"
    },
    {
      "id": "https://openalex.org/T13265",
      "display_name": "Chemistry and Applications of Tetrazoles"
    },
    {
      "id": "https://openalex.org/T12458",
      "display_name": "Chemistry and Biological Activities of Organotin Compounds"
    },
    {
      "id": "https://openalex.org/T10909",
      "display_name": "Chemistry and Health Effects of Olive Oil"
    },
    {
      "id": "https://openalex.org/T13124",
      "display_name": "Chemistry and Pharmacology of Amaryllidaceae Alkaloids"
    },
    {
      "id": "https://openalex.org/T12318",
      "display_name": "Chemistry and Pharmacology of Quinazoline Compounds"
    },
    {
      "id": "https://openalex.org/T13105",
      "display_name": "Chemistry of Pyrrolobenzodiazepines"
    },
    {
      "id": "https://openalex.org/T12973",
      "display_name": "Chemistry of Quinone Methides"
    },
    {
      "id": "https://openalex.org/T11441",
      "display_name": "Frustrated Lewis Pairs Chemistry"
    },
    {
      "id": "https://openalex.org/T10871",
      "display_name": "Gold Catalysis in Organic Synthesis"
    },
    {
      "id": "https://openalex.org/T12410",
      "display_name": "Heterocyclic Chemistry Synthesis"
    },
    {
      "id": "https://openalex.org/T10274",
      "display_name": "Heterocyclic Compounds for Drug Discovery"
    },
    {
      "id": "https://openalex.org/T13230",
      "display_name": "Indolizine Synthesis and Bioactivity Studies"
    },
    {
      "id": "https://openalex.org/T11831",
      "display_name": "Innovations in Organic Synthesis Reactions"
    },
    {
      "id": "https://openalex.org/T10405",
      "display_name": "Living Radical Polymerization"
    },
    {
      "id": "https://openalex.org/T13239",
      "display_name": "Mechanism and Applications of Wittig Reaction"
    },
    {
      "id": "https://openalex.org/T12270",
      "display_name": "Microwave-Assisted Chemistry in Organic Synthesis"
    },
    {
      "id": "https://openalex.org/T10817",
      "display_name": "Multicomponent Reactions"
    },
     {
      "id": "https://openalex.org/T11790",
      "display_name": "N-Heterocyclic Carbenes in Catalysis and Materials Chemistry"
    },
     {
      "id": "https://openalex.org/T12191",
      "display_name": "Nucleophilic Reactivity in Organic Chemistry"
    },
    {
      "id": "https://openalex.org/T11549",
      "display_name": "Olefin Metathesis Chemistry"
    },
    {
      "id": "https://openalex.org/T11746",
      "display_name": "Organic Chemistry and Catalysis"
    },
    {
      "id": "https://openalex.org/T12228",
      "display_name": "Organometallic Chemistry and Metalation"
    },
    {
      "id": "https://openalex.org/T14318",
      "display_name": "Polydiacetylene Supramolecular Chemosensors"
    },
    {
      "id": "https://openalex.org/T13013",
      "display_name": "Predicting Antioxidant Activity of Phenolic Compounds"
    },
    {
      "id": "https://openalex.org/T12527",
      "display_name": "Principles of Stereochemical Structure and Nomenclature"
    },
    {
      "id": "https://openalex.org/T12562",
      "display_name": "Pyrrole Synthesis and Applications"
    },
    {
      "id": "https://openalex.org/T14099",
      "display_name": "Recent Advances in Triazine Chemistry"
    },
    {
      "id": "https://openalex.org/T13208",
      "display_name": "Recent Developments in Ketene Dithioacetal Chemistry"
    },
    {
      "id": "https://openalex.org/T13859",
      "display_name": "Recent Developments in Organic Synthesis"
    },
    {
      "id": "https://openalex.org/T10578",
      "display_name": "Self-Assembly and Molecular Recognition in Chemistry"
    },
    {
      "id": "https://openalex.org/T10721",
      "display_name": "Surfactant Aggregation and Self-Assembly Phenomena"
    },
    {
      "id": "https://openalex.org/T13304",
      "display_name": "Synthesis and Applications of Thioamides"
    },
    {
      "id": "https://openalex.org/T13489",
      "display_name": "Synthesis and Applications of \u00df-Lactams"
    },
    {
      "id": "https://openalex.org/T14459",
      "display_name": "Synthesis and Biological Activities of Oxazolones"
    },
    {
      "id": "https://openalex.org/T13160",
      "display_name": "Synthesis and Biological Activities of Quinoxaline Derivatives"
    },
    {
      "id": "https://openalex.org/T13876",
      "display_name": "Synthesis and Properties of Heterocyclic Compounds"
    },
    {
      "id": "https://openalex.org/T12852",
      "display_name": "Thermochemical Properties of Organic Compounds"
    },
    {
      "id": "https://openalex.org/T10092",
      "display_name": "Transition Metal Catalysis"
    },
    {
      "id": "https://openalex.org/T10548",
      "display_name": "Transition Metal-Catalyzed Cross-Coupling Reactions"
    },
    {
      "id": "https://openalex.org/T10354",
      "display_name": "Transition-Metal-Catalyzed C\u2013H Bond Functionalization"
    },
    {
      "id": "https://openalex.org/T12189",
      "display_name": "Transition-Metal-Catalyzed Sulfur Chemistry"
    },
    {
      "id": "https://openalex.org/T12893",
      "display_name": "Understanding Reactivity in Organic Reactions"
    }
  ],
  "works_count": 39830,
  "cited_by_count": 937006,
  "updated_date": "2024-08-26T06:13:20.821437",
  "created_date": "2024-01-23"
}
}