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OpenAlex: !!python/object/new:pyalex.api.Topic
{
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  "id": "https://openalex.org/T11440",
    cited_by_count: 878338
   "display_name": "Click Chemistry in Chemical Biology and Drug Development",
    created_date: '2024-01-23'
  "description": "This cluster of papers focuses on the application of click chemistry, particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology and drug development. It explores diverse chemical functionality, bioorthogonal chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development of enzyme inhibitors.",
    description: This cluster of papers focuses on the application of click chemistry,
  "keywords": [
      particularly the copper-catalyzed azide-alkyne cycloaddition, in chemical biology
    "Click Chemistry",
      and drug development. It explores diverse chemical functionality, bioorthogonal
     "Copper-Catalyzed Cycloaddition",
      chemistry, protein labeling, in vivo imaging, triazole synthesis, and the development
    "Bioorthogonal Chemistry",
      of enzyme inhibitors.
    "Azides and Alkynes",
    display_name: Click Chemistry in Chemical Biology and Drug Development
     "Chemical Functionality",
     domain:
    "Drug Discovery",
      display_name: Physical Sciences
    "Protein Labeling",
      id: https://openalex.org/domains/3
     "In Vivo Imaging",
     field:
     "Triazole Synthesis",
      display_name: Chemistry
    "Enzyme Inhibitors"
      id: https://openalex.org/fields/16
  ],
     id: https://openalex.org/T11440
  "ids": {
     ids:
    "openalex": "https://openalex.org/T11440",
      openalex: https://openalex.org/T11440
    "wikipedia": "https://en.wikipedia.org/wiki/Click_chemistry"
      wikipedia: https://en.wikipedia.org/wiki/Click_chemistry
  },
    keywords:
  "subfield": {
    - Click Chemistry
     "id": "https://openalex.org/subfields/1605",
     - Copper-Catalyzed Cycloaddition
     "display_name": "Organic Chemistry"
     - Bioorthogonal Chemistry
  },
    - Azides and Alkynes
  "field": {
    - Chemical Functionality
     "id": "https://openalex.org/fields/16",
     - Drug Discovery
     "display_name": "Chemistry"
     - Protein Labeling
  },
    - In Vivo Imaging
  "domain": {
    - Triazole Synthesis
     "id": "https://openalex.org/domains/3",
    - Enzyme Inhibitors
     "display_name": "Physical Sciences"
    siblings:
  },
     - display_name: Advances in Photoinitiated Polymerization Reactions
  "siblings": [
      id: https://openalex.org/T12570
    {
     - display_name: Amide Chemistry and Synthesis
       "id": "https://openalex.org/T12570",
       id: https://openalex.org/T13649
      "display_name": "Advances in Photoinitiated Polymerization Reactions"
    - display_name: Applications of Photoredox Catalysis in Organic Synthesis
    },
       id: https://openalex.org/T10701
    {
    - display_name: Aromaticity in Organic Molecules and Materials
       "id": "https://openalex.org/T13649",
       id: https://openalex.org/T11298
      "display_name": "Amide Chemistry and Synthesis"
    - display_name: Aryne Chemistry in Organic Synthesis
    },
       id: https://openalex.org/T12653
    {
    - display_name: Asymmetric Catalysis
       "id": "https://openalex.org/T10701",
       id: https://openalex.org/T10013
      "display_name": "Applications of Photoredox Catalysis in Organic Synthesis"
    - display_name: Atroposelective Synthesis of Axially Chiral Compounds
    },
       id: https://openalex.org/T13115
    {
    - display_name: Bioorganometallic Chemistry of Ferrocene Derivatives
       "id": "https://openalex.org/T11298",
      id: https://openalex.org/T13833
      "display_name": "Aromaticity in Organic Molecules and Materials"
     - display_name: Catalytic C-H Amination Reactions
    },
       id: https://openalex.org/T12251
    {
    - display_name: Catalytic Carbene Chemistry in Organic Synthesis
       "id": "https://openalex.org/T12653",
       id: https://openalex.org/T11611
      "display_name": "Aryne Chemistry in Organic Synthesis"
    - display_name: Catalytic Oxidation of Alcohols
    },
       id: https://openalex.org/T11989
    {
    - display_name: Catalytic Reduction of Nitro Compounds
       "id": "https://openalex.org/T10013",
       id: https://openalex.org/T12240
      "display_name": "Asymmetric Catalysis"
    - display_name: Chemical Composition and Bioactivity of Maple Syrup
    },
       id: https://openalex.org/T14297
     {
    - display_name: Chemical Constituents and Production of Agarwood
       "id": "https://openalex.org/T13115",
       id: https://openalex.org/T13568
      "display_name": "Atroposelective Synthesis of Axially Chiral Compounds"
    - display_name: Chemical Glycobiology and Therapeutic Applications
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       id: https://openalex.org/T10835
    {
    - display_name: Chemistry and Applications of Antimicrobial Polymers
       "id": "https://openalex.org/T13833",
       id: https://openalex.org/T12526
      "display_name": "Bioorganometallic Chemistry of Ferrocene Derivatives"
    - display_name: Chemistry and Applications of Fullerenes
    },
       id: https://openalex.org/T10956
    {
    - display_name: Chemistry and Applications of Phosphonates
       "id": "https://openalex.org/T12251",
       id: https://openalex.org/T11748
      "display_name": "Catalytic C-H Amination Reactions"
    - display_name: Chemistry and Applications of Tetrazoles
    },
       id: https://openalex.org/T13265
    {
    - display_name: Chemistry and Biological Activities of Organotin Compounds
       "id": "https://openalex.org/T11611",
       id: https://openalex.org/T12458
      "display_name": "Catalytic Carbene Chemistry in Organic Synthesis"
    - display_name: Chemistry and Health Effects of Olive Oil
    },
       id: https://openalex.org/T10909
    {
    - display_name: Chemistry and Pharmacology of Amaryllidaceae Alkaloids
       "id": "https://openalex.org/T11989",
       id: https://openalex.org/T13124
      "display_name": "Catalytic Oxidation of Alcohols"
    - display_name: Chemistry and Pharmacology of Quinazoline Compounds
    },
       id: https://openalex.org/T12318
    {
    - display_name: Chemistry of Pyrrolobenzodiazepines
       "id": "https://openalex.org/T12240",
       id: https://openalex.org/T13105
      "display_name": "Catalytic Reduction of Nitro Compounds"
    - display_name: Chemistry of Quinone Methides
    },
       id: https://openalex.org/T12973
    {
    - display_name: Frustrated Lewis Pairs Chemistry
       "id": "https://openalex.org/T14297",
       id: https://openalex.org/T11441
      "display_name": "Chemical Composition and Bioactivity of Maple Syrup"
    - display_name: Gold Catalysis in Organic Synthesis
    },
      id: https://openalex.org/T10871
    {
     - display_name: Heterocyclic Chemistry Synthesis
       "id": "https://openalex.org/T13568",
       id: https://openalex.org/T12410
      "display_name": "Chemical Constituents and Production of Agarwood"
    - display_name: Heterocyclic Compounds for Drug Discovery
    },
       id: https://openalex.org/T10274
    {
    - display_name: Indolizine Synthesis and Bioactivity Studies
       "id": "https://openalex.org/T10835",
       id: https://openalex.org/T13230
      "display_name": "Chemical Glycobiology and Therapeutic Applications"
    - display_name: Innovations in Organic Synthesis Reactions
    },
      id: https://openalex.org/T11831
    {
     - display_name: Living Radical Polymerization
       "id": "https://openalex.org/T12526",
       id: https://openalex.org/T10405
      "display_name": "Chemistry and Applications of Antimicrobial Polymers"
    - display_name: Mechanism and Applications of Wittig Reaction
    },
       id: https://openalex.org/T13239
    {
    - display_name: Microwave-Assisted Chemistry in Organic Synthesis
       "id": "https://openalex.org/T10956",
       id: https://openalex.org/T12270
      "display_name": "Chemistry and Applications of Fullerenes"
    - display_name: Multicomponent Reactions
    },
       id: https://openalex.org/T10817
    {
    - display_name: N-Heterocyclic Carbenes in Catalysis and Materials Chemistry
       "id": "https://openalex.org/T11748",
       id: https://openalex.org/T11790
      "display_name": "Chemistry and Applications of Phosphonates"
    - display_name: Nucleophilic Reactivity in Organic Chemistry
    },
      id: https://openalex.org/T12191
    {
     - display_name: Olefin Metathesis Chemistry
       "id": "https://openalex.org/T13265",
       id: https://openalex.org/T11549
      "display_name": "Chemistry and Applications of Tetrazoles"
    - display_name: Organic Chemistry and Catalysis
    },
       id: https://openalex.org/T11746
    {
    - display_name: Organometallic Chemistry and Metalation
       "id": "https://openalex.org/T12458",
       id: https://openalex.org/T12228
      "display_name": "Chemistry and Biological Activities of Organotin Compounds"
    - display_name: Polydiacetylene Supramolecular Chemosensors
    },
       id: https://openalex.org/T14318
    {
    - display_name: Predicting Antioxidant Activity of Phenolic Compounds
       "id": "https://openalex.org/T10909",
       id: https://openalex.org/T13013
      "display_name": "Chemistry and Health Effects of Olive Oil"
    - display_name: Principles of Stereochemical Structure and Nomenclature
    },
       id: https://openalex.org/T12527
    {
    - display_name: Pyrrole Synthesis and Applications
       "id": "https://openalex.org/T13124",
       id: https://openalex.org/T12562
      "display_name": "Chemistry and Pharmacology of Amaryllidaceae Alkaloids"
    - display_name: Recent Advances in Triazine Chemistry
    },
      id: https://openalex.org/T14099
    {
    - display_name: Recent Developments in Ketene Dithioacetal Chemistry
       "id": "https://openalex.org/T12318",
       id: https://openalex.org/T13208
      "display_name": "Chemistry and Pharmacology of Quinazoline Compounds"
    - display_name: Recent Developments in Organic Synthesis
    },
       id: https://openalex.org/T13859
    {
    - display_name: Self-Assembly and Molecular Recognition in Chemistry
       "id": "https://openalex.org/T13105",
       id: https://openalex.org/T10578
      "display_name": "Chemistry of Pyrrolobenzodiazepines"
    - display_name: Surfactant Aggregation and Self-Assembly Phenomena
    },
       id: https://openalex.org/T10721
     {
    - display_name: Synthesis and Applications of Thioamides
       "id": "https://openalex.org/T12973",
       id: https://openalex.org/T13304
      "display_name": "Chemistry of Quinone Methides"
    - display_name: "Synthesis and Applications of \xDF-Lactams"
    },
       id: https://openalex.org/T13489
    {
    - display_name: Synthesis and Biological Activities of Oxazolones
       "id": "https://openalex.org/T11441",
       id: https://openalex.org/T14459
      "display_name": "Frustrated Lewis Pairs Chemistry"
    - display_name: Synthesis and Biological Activities of Quinoxaline Derivatives
    },
       id: https://openalex.org/T13160
    {
    - display_name: Synthesis and Properties of Heterocyclic Compounds
       "id": "https://openalex.org/T10871",
       id: https://openalex.org/T13876
      "display_name": "Gold Catalysis in Organic Synthesis"
    - display_name: Thermochemical Properties of Organic Compounds
    },
       id: https://openalex.org/T12852
     {
    - display_name: Transition Metal Catalysis
       "id": "https://openalex.org/T12410",
       id: https://openalex.org/T10092
      "display_name": "Heterocyclic Chemistry Synthesis"
    - display_name: Transition Metal-Catalyzed Cross-Coupling Reactions
    },
       id: https://openalex.org/T10548
    {
    - display_name: "Transition-Metal-Catalyzed C\u2013H Bond Functionalization"
       "id": "https://openalex.org/T10274",
       id: https://openalex.org/T10354
      "display_name": "Heterocyclic Compounds for Drug Discovery"
    - display_name: Transition-Metal-Catalyzed Sulfur Chemistry
    },
       id: https://openalex.org/T12189
    {
    - display_name: Understanding Reactivity in Organic Reactions
       "id": "https://openalex.org/T13230",
       id: https://openalex.org/T12893
      "display_name": "Indolizine Synthesis and Bioactivity Studies"
    subfield:
    },
       display_name: Organic Chemistry
    {
       id: https://openalex.org/subfields/1605
       "id": "https://openalex.org/T11831",
    updated_date: '2024-05-20T05:11:38.075947'
      "display_name": "Innovations in Organic Synthesis Reactions"
    works_count: 39486
    },
    {
       "id": "https://openalex.org/T10405",
      "display_name": "Living Radical Polymerization"
    },
     {
       "id": "https://openalex.org/T13239",
      "display_name": "Mechanism and Applications of Wittig Reaction"
    },
    {
       "id": "https://openalex.org/T12270",
      "display_name": "Microwave-Assisted Chemistry in Organic Synthesis"
    },
    {
       "id": "https://openalex.org/T10817",
      "display_name": "Multicomponent Reactions"
    },
    {
       "id": "https://openalex.org/T11790",
      "display_name": "N-Heterocyclic Carbenes in Catalysis and Materials Chemistry"
    },
    {
       "id": "https://openalex.org/T12191",
      "display_name": "Nucleophilic Reactivity in Organic Chemistry"
    },
    {
       "id": "https://openalex.org/T11549",
      "display_name": "Olefin Metathesis Chemistry"
    },
    {
       "id": "https://openalex.org/T11746",
      "display_name": "Organic Chemistry and Catalysis"
    },
    {
      "id": "https://openalex.org/T12228",
      "display_name": "Organometallic Chemistry and Metalation"
    },
    {
       "id": "https://openalex.org/T14318",
      "display_name": "Polydiacetylene Supramolecular Chemosensors"
    },
    {
       "id": "https://openalex.org/T13013",
      "display_name": "Predicting Antioxidant Activity of Phenolic Compounds"
    },
    {
       "id": "https://openalex.org/T12527",
      "display_name": "Principles of Stereochemical Structure and Nomenclature"
    },
    {
       "id": "https://openalex.org/T12562",
      "display_name": "Pyrrole Synthesis and Applications"
    },
    {
       "id": "https://openalex.org/T14099",
      "display_name": "Recent Advances in Triazine Chemistry"
    },
    {
       "id": "https://openalex.org/T13208",
      "display_name": "Recent Developments in Ketene Dithioacetal Chemistry"
    },
    {
       "id": "https://openalex.org/T13859",
      "display_name": "Recent Developments in Organic Synthesis"
    },
    {
       "id": "https://openalex.org/T10578",
      "display_name": "Self-Assembly and Molecular Recognition in Chemistry"
    },
    {
       "id": "https://openalex.org/T10721",
      "display_name": "Surfactant Aggregation and Self-Assembly Phenomena"
    },
    {
       "id": "https://openalex.org/T13304",
      "display_name": "Synthesis and Applications of Thioamides"
    },
    {
       "id": "https://openalex.org/T13489",
      "display_name": "Synthesis and Applications of \u00df-Lactams"
    },
    {
       "id": "https://openalex.org/T14459",
      "display_name": "Synthesis and Biological Activities of Oxazolones"
    },
    {
       "id": "https://openalex.org/T13160",
      "display_name": "Synthesis and Biological Activities of Quinoxaline Derivatives"
    },
    {
       "id": "https://openalex.org/T13876",
      "display_name": "Synthesis and Properties of Heterocyclic Compounds"
    },
    {
       "id": "https://openalex.org/T12852",
       "display_name": "Thermochemical Properties of Organic Compounds"
    },
    {
       "id": "https://openalex.org/T10092",
      "display_name": "Transition Metal Catalysis"
    },
    {
      "id": "https://openalex.org/T10548",
      "display_name": "Transition Metal-Catalyzed Cross-Coupling Reactions"
    },
    {
      "id": "https://openalex.org/T10354",
      "display_name": "Transition-Metal-Catalyzed C\u2013H Bond Functionalization"
    },
    {
      "id": "https://openalex.org/T12189",
      "display_name": "Transition-Metal-Catalyzed Sulfur Chemistry"
    },
    {
      "id": "https://openalex.org/T12893",
      "display_name": "Understanding Reactivity in Organic Reactions"
    }
  ],
  "works_count": 39830,
  "cited_by_count": 937006,
  "updated_date": "2024-08-26T06:13:20.821437",
  "created_date": "2024-01-23"
}
Retrieved from "https://geokb.wikibase.cloud/wiki/Special:MobileDiff/1124780"