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OpenAlex: !!python/object/new:pyalex.api.Topic
{
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  "id": "https://openalex.org/T11078",
    cited_by_count: 1042580
   "display_name": "Molecular Mechanisms of Inflammasome Activation and Regulation",
    created_date: '2024-01-23'
  "description": "This cluster of papers focuses on the molecular mechanisms of inflammasome activation, regulation, and its role in inflammatory responses, cell death (pyroptosis), and immune-related diseases. It covers topics such as NLRP3 inflammasome, interleukin-1, caspase-1, and the involvement of mitochondria in inflammasome activation.",
    description: This cluster of papers focuses on the molecular mechanisms of inflammasome
  "keywords": [
      activation, regulation, and its role in inflammatory responses, cell death (pyroptosis),
     "Inflammasome",
      and immune-related diseases. It covers topics such as NLRP3 inflammasome, interleukin-1,
    "NLRP3",
      caspase-1, and the involvement of mitochondria in inflammasome activation.
     "Pyroptosis",
     display_name: Molecular Mechanisms of Inflammasome Activation and Regulation
    "Interleukin-1",
     domain:
    "Caspase-1",
      display_name: Life Sciences
     "Inflammation",
      id: https://openalex.org/domains/1
    "Cell Death",
     field:
     "Immune Response",
      display_name: Biochemistry, Genetics and Molecular Biology
    "Mitochondria",
      id: https://openalex.org/fields/13
     "Autoinflammatory Diseases"
     id: https://openalex.org/T11078
  ],
     ids:
  "ids": {
      openalex: https://openalex.org/T11078
    "openalex": "https://openalex.org/T11078",
      wikipedia: https://en.wikipedia.org/wiki/Inflammasome
    "wikipedia": "https://en.wikipedia.org/wiki/Inflammasome"
    keywords:
  },
     - Inflammasome
  "subfield": {
     - NLRP3
     "id": "https://openalex.org/subfields/1312",
    - Pyroptosis
     "display_name": "Molecular Biology"
    - Interleukin-1
  },
     - Caspase-1
  "field": {
     - Inflammation
     "id": "https://openalex.org/fields/13",
    - Cell Death
     "display_name": "Biochemistry, Genetics and Molecular Biology"
    - Immune Response
  },
     - Mitochondria
  "domain": {
    - Autoinflammatory Diseases
     "id": "https://openalex.org/domains/1",
     siblings:
     "display_name": "Life Sciences"
     - display_name: '14-3-3 Proteins: Structure, Function, and Regulation'
  },
      id: https://openalex.org/T13526
  "siblings": [
    - display_name: Advances in Metabolomics Research
     {
       id: https://openalex.org/T10836
      "id": "https://openalex.org/T13526",
    - display_name: Analysis of Gene Interaction Networks
      "display_name": "14-3-3 Proteins: Structure, Function, and Regulation"
       id: https://openalex.org/T10887
    },
    - display_name: ATP Synthase Function and Regulation
    {
       id: https://openalex.org/T12763
      "id": "https://openalex.org/T10836",
    - display_name: Bacterial Biofilms and Quorum Sensing Mechanisms
      "display_name": "Advances in Metabolomics Research"
       id: https://openalex.org/T10593
    },
    - display_name: Bioactive Limonoids in Medicinal Plants
    {
       id: https://openalex.org/T12685
       "id": "https://openalex.org/T10887",
    - display_name: Bioactive Peptides in Food and Health
      "display_name": "Analysis of Gene Interaction Networks"
       id: https://openalex.org/T11561
    },
    - display_name: Bioactivity of Steroidal Saponins in Medicinal Plants
    {
      id: https://openalex.org/T12215
       "id": "https://openalex.org/T12763",
    - display_name: Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids
      "display_name": "ATP Synthase Function and Regulation"
       id: https://openalex.org/T13188
    },
    - display_name: Biochemistry, Pharmacology, and Medical Use of Bromelain
    {
       id: https://openalex.org/T13725
       "id": "https://openalex.org/T10593",
    - display_name: Biogenesis and Functions of Circular RNAs
      "display_name": "Bacterial Biofilms and Quorum Sensing Mechanisms"
       id: https://openalex.org/T11765
    },
    - display_name: Biological Activities of Diterpenoids from Medicinal Plants
    {
       id: https://openalex.org/T12530
       "id": "https://openalex.org/T12685",
    - display_name: Biological Activities of Phenothiazines and Related Compounds
      "display_name": "Bioactive Limonoids in Medicinal Plants"
       id: https://openalex.org/T13454
    },
    - display_name: Biological Activities of Prenylated Flavonoids
    {
       id: https://openalex.org/T12257
       "id": "https://openalex.org/T11561",
    - display_name: Biological Activities of Triterpenoids and Saponins
      "display_name": "Bioactive Peptides in Food and Health"
       id: https://openalex.org/T11385
    },
    - display_name: Biological Activity of Diterpenoids and Biflavonoids
    {
       id: https://openalex.org/T13221
       "id": "https://openalex.org/T12215",
    - display_name: Biological Agents for Bioterrorism
      "display_name": "Bioactivity of Steroidal Saponins in Medicinal Plants"
       id: https://openalex.org/T11515
    },
    - display_name: Biological Methane Utilization and Metabolism
    {
       id: https://openalex.org/T12688
      "id": "https://openalex.org/T13188",
    - display_name: Bioluminescence Imaging and Reporter Systems
      "display_name": "Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids"
      id: https://openalex.org/T12561
    },
    - display_name: Biomedical Ontologies and Text Mining
    {
       id: https://openalex.org/T11710
       "id": "https://openalex.org/T13725",
    - display_name: Biosynthesis and Engineering of Terpenoids
      "display_name": "Biochemistry, Pharmacology, and Medical Use of Bromelain"
       id: https://openalex.org/T11882
    },
    - display_name: Biosynthesis and Pharmacological Activities of Lignans
    {
       id: https://openalex.org/T12360
       "id": "https://openalex.org/T11765",
    - display_name: Calcineurin-NFAT Signaling in Transcriptional Regulation
      "display_name": "Biogenesis and Functions of Circular RNAs"
       id: https://openalex.org/T12620
    },
    - display_name: Challenges and Innovations in Bioinformatics Education
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       id: https://openalex.org/T13937
       "id": "https://openalex.org/T12530",
    - display_name: Chitin Metabolism in Insects and Mammals
      "display_name": "Biological Activities of Diterpenoids from Medicinal Plants"
       id: https://openalex.org/T12683
    },
    - display_name: Chromatin Remodeling in Cancer and Development
    {
       id: https://openalex.org/T12820
       "id": "https://openalex.org/T13454",
    - display_name: Clustered Regularly Interspaced Short Palindromic Repeats and
      "display_name": "Biological Activities of Phenothiazines and Related Compounds"
        CRISPR-associated proteins
    },
       id: https://openalex.org/T10878
    {
    - display_name: Comprehensive Integration of Single-Cell Transcriptomic Data
       "id": "https://openalex.org/T12257",
       id: https://openalex.org/T11289
      "display_name": "Biological Activities of Prenylated Flavonoids"
    - display_name: Cyclotide Bioengineering and Protein Anchoring Mechanisms
    },
       id: https://openalex.org/T13326
    {
    - display_name: Diversity and Function of Gut Microbiome
       "id": "https://openalex.org/T11385",
      id: https://openalex.org/T10066
      "display_name": "Biological Activities of Triterpenoids and Saponins"
    - display_name: Diversity and Systematics of Yeasts
    },
       id: https://openalex.org/T12668
    {
    - display_name: DNA Barcoding for Food Authentication and Fraud Detection
       "id": "https://openalex.org/T13221",
       id: https://openalex.org/T12388
      "display_name": "Biological Activity of Diterpenoids and Biflavonoids"
    - display_name: DNA Nanotechnology and Bioanalytical Applications
    },
       id: https://openalex.org/T10207
    {
    - display_name: 'DNA Topoisomerases: Structure, Function, and Inhibition'
       "id": "https://openalex.org/T11515",
       id: https://openalex.org/T11845
      "display_name": "Biological Agents for Bioterrorism"
    - display_name: DNA-based Computing and Data Storage
    },
       id: https://openalex.org/T12029
    {
    - display_name: Elicitor Signal Transduction for Metabolite Production
       "id": "https://openalex.org/T12688",
       id: https://openalex.org/T10240
      "display_name": "Biological Methane Utilization and Metabolism"
    - display_name: Enzyme Immobilization Techniques
    },
       id: https://openalex.org/T10404
    {
    - display_name: Epigenetic Modifications and Their Functional Implications
       "id": "https://openalex.org/T12561",
       id: https://openalex.org/T10269
      "display_name": "Bioluminescence Imaging and Reporter Systems"
    - display_name: Exosome Biology and Function in Intercellular Communication
    },
       id: https://openalex.org/T10773
    {
    - display_name: Fibroblast Growth Factor Signaling Pathway
      "id": "https://openalex.org/T11710",
       id: https://openalex.org/T12287
      "display_name": "Biomedical Ontologies and Text Mining"
    - display_name: Functions and Regulation of RNA Editing by ADARs
    },
      id: https://openalex.org/T12610
    {
    - display_name: G-Quadruplex DNA Structures and Functions
       "id": "https://openalex.org/T11882",
       id: https://openalex.org/T10432
      "display_name": "Biosynthesis and Engineering of Terpenoids"
    - display_name: Genomic Expression and Function in Yeast Organism
    },
       id: https://openalex.org/T10497
    {
    - display_name: Genomic Signal Processing and Analysis Techniques
       "id": "https://openalex.org/T12360",
       id: https://openalex.org/T12946
      "display_name": "Biosynthesis and Pharmacological Activities of Lignans"
    - display_name: Global Diversity of Microbial Eukaryotes and Their Evolution
    },
       id: https://openalex.org/T11879
    {
    - display_name: Glycosylation in Health and Disease
       "id": "https://openalex.org/T12620",
       id: https://openalex.org/T10602
      "display_name": "Calcineurin-NFAT Signaling in Transcriptional Regulation"
    - display_name: Hedgehog Signaling in Development and Cancer
    },
       id: https://openalex.org/T12009
    {
    - display_name: Heme Oxygenase and Carbon Monoxide Research
       "id": "https://openalex.org/T13937",
       id: https://openalex.org/T11848
      "display_name": "Challenges and Innovations in Bioinformatics Education"
    - display_name: Induction and Differentiation of Pluripotent Stem Cells
    },
       id: https://openalex.org/T10505
    {
    - display_name: Lipid Rafts and Membrane Dynamics
       "id": "https://openalex.org/T12683",
       id: https://openalex.org/T10407
      "display_name": "Chitin Metabolism in Insects and Mammals"
    - display_name: Magnetosome Formation in Prokaryotes
    },
       id: https://openalex.org/T11786
    {
    - display_name: Mammalian MAP Kinase Signaling Pathways
       "id": "https://openalex.org/T12820",
      id: https://openalex.org/T11533
      "display_name": "Chromatin Remodeling in Cancer and Development"
    - display_name: Mechanisms and Applications of RNA Interference
    },
       id: https://openalex.org/T10725
    {
    - display_name: Metabolic Engineering and Synthetic Biology
       "id": "https://openalex.org/T10878",
       id: https://openalex.org/T10932
      "display_name": "Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins"
    - display_name: Metabolism and Functions of Coenzyme Q
    },
       id: https://openalex.org/T13012
    {
    - display_name: Microarray Data Analysis and Gene Expression Profiling
       "id": "https://openalex.org/T11289",
       id: https://openalex.org/T10885
      "display_name": "Comprehensive Integration of Single-Cell Transcriptomic Data"
    - display_name: Microbial Production of Polyglutamic Acid
    },
       id: https://openalex.org/T14285
    {
    - display_name: Microbial Transformation of Steroids
       "id": "https://openalex.org/T13326",
       id: https://openalex.org/T13736
      "display_name": "Cyclotide Bioengineering and Protein Anchoring Mechanisms"
    - display_name: Mitochondrial Dynamics and Reactive Oxygen Species Regulation
    },
       id: https://openalex.org/T10301
    {
    - display_name: Molecular Biology of Steroidogenesis and Disorders
       "id": "https://openalex.org/T10066",
       id: https://openalex.org/T11956
      "display_name": "Diversity and Function of Gut Microbiome"
    - display_name: Molecular Chaperones in Protein Folding and Disease
    },
       id: https://openalex.org/T10934
    {
    - display_name: Molecular Mechanisms and Medical Applications of Ginseng
      "id": "https://openalex.org/T12668",
       id: https://openalex.org/T11889
      "display_name": "Diversity and Systematics of Yeasts"
    - display_name: Molecular Mechanisms of Amyloidosis
    },
      id: https://openalex.org/T11305
    {
    - display_name: Molecular Mechanisms of Angiogenesis and Vascular Function
       "id": "https://openalex.org/T12388",
       id: https://openalex.org/T10422
      "display_name": "DNA Barcoding for Food Authentication and Fraud Detection"
    - display_name: Molecular Mechanisms of Apoptosis and Cell Death
    },
       id: https://openalex.org/T10294
    {
    - display_name: Molecular Mechanisms of Aquaporins in Physiology and Disease
       "id": "https://openalex.org/T10207",
       id: https://openalex.org/T10724
      "display_name": "DNA Nanotechnology and Bioanalytical Applications"
    - display_name: Molecular Mechanisms of Cardiac Development and Regeneration
    },
       id: https://openalex.org/T11677
    {
    - display_name: Molecular Mechanisms of DNA Damage Response
       "id": "https://openalex.org/T11845",
       id: https://openalex.org/T10123
      "display_name": "DNA Topoisomerases: Structure, Function, and Inhibition"
    - display_name: Molecular Mechanisms of Flavonoid Biosynthesis in Plants
    },
       id: https://openalex.org/T11237
    {
    - display_name: Molecular Mechanisms of Heme Biosynthesis and Related Disorders
       "id": "https://openalex.org/T12029",
       id: https://openalex.org/T12441
      "display_name": "DNA-based Computing and Data Storage"
    - display_name: Molecular Mechanisms of Insect Resistance to Xenobiotics
    },
       id: https://openalex.org/T11075
    {
    - display_name: Molecular Mechanisms of Ion Channels Regulation
       "id": "https://openalex.org/T10240",
       id: https://openalex.org/T10493
      "display_name": "Elicitor Signal Transduction for Metabolite Production"
    - display_name: Molecular Mechanisms of Kidney Development and Disease
    },
       id: https://openalex.org/T12140
    {
    - display_name: Molecular Mechanisms of Metastasis Suppressor Genes
       "id": "https://openalex.org/T10404",
      id: https://openalex.org/T13437
      "display_name": "Enzyme Immobilization Techniques"
    - display_name: Molecular Mechanisms of Muscle Regeneration and Atrophy
    },
       id: https://openalex.org/T10441
    {
    - display_name: Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling
       "id": "https://openalex.org/T10269",
       id: https://openalex.org/T11219
      "display_name": "Epigenetic Modifications and Their Functional Implications"
    - display_name: Molecular Mechanisms of Photosynthesis and Photoprotection
    },
       id: https://openalex.org/T10303
    {
    - display_name: Molecular Mechanisms of Planarian Regeneration
       "id": "https://openalex.org/T10773",
       id: https://openalex.org/T12789
      "display_name": "Exosome Biology and Function in Intercellular Communication"
    - display_name: Molecular Mechanisms of Pollen Development and Function
    },
       id: https://openalex.org/T11927
    {
    - display_name: Molecular Mechanisms of Ras Signaling Pathways
       "id": "https://openalex.org/T12287",
       id: https://openalex.org/T10169
      "display_name": "Fibroblast Growth Factor Signaling Pathway"
    - display_name: Molecular Mechanisms of Retinal Degeneration and Regeneration
    },
       id: https://openalex.org/T10691
    {
    - display_name: Molecular Mechanisms of Tooth Development and Morphogenesis
       "id": "https://openalex.org/T12610",
       id: https://openalex.org/T11919
      "display_name": "Functions and Regulation of RNA Editing by ADARs"
    - display_name: Molecular Regulation and Clinical Applications of PDEs
    },
       id: https://openalex.org/T12434
    {
    - display_name: Molecular Regulation of Sulfur Metabolism in Plants
      "id": "https://openalex.org/T10432",
       id: https://openalex.org/T12566
      "display_name": "G-Quadruplex DNA Structures and Functions"
    - display_name: Molecular Systematics of Gesneriaceae and Allies
    },
      id: https://openalex.org/T14049
    {
    - display_name: mTOR Signaling in Growth and Disease
       "id": "https://openalex.org/T10497",
       id: https://openalex.org/T10952
      "display_name": "Genomic Expression and Function in Yeast Organism"
    - display_name: Notch Signaling Pathway in Development and Disease
    },
       id: https://openalex.org/T10268
    {
    - display_name: Nucleotide Metabolism and Enzyme Regulation
       "id": "https://openalex.org/T12946",
       id: https://openalex.org/T12827
      "display_name": "Genomic Signal Processing and Analysis Techniques"
    - display_name: Oxidation States in Biochemistry and Medicine
    },
       id: https://openalex.org/T14135
    {
    - display_name: Peptide Synthesis and Drug Discovery
       "id": "https://openalex.org/T11879",
       id: https://openalex.org/T10911
      "display_name": "Global Diversity of Microbial Eukaryotes and Their Evolution"
    - display_name: Peroxisome Proliferator-Activated Receptors
    },
       id: https://openalex.org/T11072
    {
    - display_name: Polyamines and Biogenic Amines in Biology and Health
       "id": "https://openalex.org/T10602",
       id: https://openalex.org/T11924
      "display_name": "Glycosylation in Health and Disease"
    - display_name: Prediction of Peptide-MHC Binding Affinity
    },
       id: https://openalex.org/T12576
    {
    - display_name: Prediction of Protein Subcellular Localization
       "id": "https://openalex.org/T12009",
       id: https://openalex.org/T12254
      "display_name": "Hedgehog Signaling in Development and Cancer"
    - display_name: 'Prion Diseases: Causes and Molecular Basis'
    },
       id: https://openalex.org/T11335
    {
    - display_name: Protein Aggregation and Biopharmaceutical Stability
       "id": "https://openalex.org/T11848",
      id: https://openalex.org/T11124
      "display_name": "Heme Oxygenase and Carbon Monoxide Research"
    - display_name: Protein Arginine Methylation in Mammals
    },
       id: https://openalex.org/T13157
    {
    - display_name: Protein Binding Specificity in Human Serum Albumin
       "id": "https://openalex.org/T10505",
       id: https://openalex.org/T11908
      "display_name": "Induction and Differentiation of Pluripotent Stem Cells"
    - display_name: Protein Microarray Technology and Applications
    },
       id: https://openalex.org/T12867
    {
    - display_name: Protein Structure Prediction and Analysis
       "id": "https://openalex.org/T10407",
       id: https://openalex.org/T10044
      "display_name": "Lipid Rafts and Membrane Dynamics"
    - display_name: Protein Tyrosine Phosphatases in Human Health and Disease
    },
       id: https://openalex.org/T12104
    {
    - display_name: Protein-DNA Interaction Dynamics in Living Cells
       "id": "https://openalex.org/T11786",
       id: https://openalex.org/T13187
      "display_name": "Magnetosome Formation in Prokaryotes"
    - display_name: 'Pyrrolizidine Alkaloids: Toxicity, Metabolism, and Health Implications'
    },
       id: https://openalex.org/T12756
    {
    - display_name: Real-Time Polymerase Chain Reaction
       "id": "https://openalex.org/T11533",
       id: https://openalex.org/T11970
      "display_name": "Mammalian MAP Kinase Signaling Pathways"
    - display_name: Recombinant Protein Production in Mammalian and Insect Cells
    },
       id: https://openalex.org/T11663
    {
    - display_name: Redox Signaling and Oxidative Stress
      "id": "https://openalex.org/T10725",
       id: https://openalex.org/T11884
      "display_name": "Mechanisms and Applications of RNA Interference"
    - display_name: Regulation and Functions of FoxO Transcription Factors
    },
      id: https://openalex.org/T12835
    {
    - display_name: Regulation of Chromatin Structure and Function
       "id": "https://openalex.org/T10932",
       id: https://openalex.org/T10222
      "display_name": "Metabolic Engineering and Synthetic Biology"
    - display_name: Regulation of RNA Processing and Function
    },
       id: https://openalex.org/T10604
    {
    - display_name: Research on Rhodiola rosea and Salidroside
       "id": "https://openalex.org/T13012",
       id: https://openalex.org/T13651
      "display_name": "Metabolism and Functions of Coenzyme Q"
    - display_name: Research on Synthetic Phosphoethanolamine and its Effects
    },
       id: https://openalex.org/T14065
    {
    - display_name: Ribosome Structure and Translation Mechanisms
       "id": "https://openalex.org/T10885",
       id: https://openalex.org/T10521
      "display_name": "Microarray Data Analysis and Gene Expression Profiling"
    - display_name: RNA Methylation and Modification in Gene Expression
    },
       id: https://openalex.org/T11482
    {
    - display_name: RNA Sequencing Data Analysis
       "id": "https://openalex.org/T14285",
       id: https://openalex.org/T10015
      "display_name": "Microbial Production of Polyglutamic Acid"
    - display_name: Role of AMP-Activated Protein Kinase in Cellular Metabolism
    },
       id: https://openalex.org/T11339
    {
    - display_name: Role of Carbonic Anhydrases in Medicine and Biotechnology
       "id": "https://openalex.org/T13736",
       id: https://openalex.org/T12412
      "display_name": "Microbial Transformation of Steroids"
    - display_name: Role of CCN Proteins in Signaling Pathways
    },
       id: https://openalex.org/T13223
    {
    - display_name: Role of Glutathione in Oxidative Stress Response
       "id": "https://openalex.org/T10301",
      id: https://openalex.org/T12187
      "display_name": "Mitochondrial Dynamics and Reactive Oxygen Species Regulation"
    - display_name: Role of Histone Deacetylases in Cellular Regulation
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      "display_name": "RNA Sequencing Data Analysis"
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      "display_name": "Role of AMP-Activated Protein Kinase in Cellular Metabolism"
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      "display_name": "Transforming Growth Factor Beta Signaling Pathway"
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Retrieved from "https://geokb.wikibase.cloud/wiki/Special:MobileDiff/1123798"