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OpenAlex: !!python/object/new:pyalex.api.Topic
{
   dictitems:
  "id": "https://openalex.org/T10371",
    cited_by_count: 2801554
   "display_name": "Innate Immune Recognition and Signaling Pathways",
    created_date: '2024-01-23'
  "description": "This cluster of papers focuses on the recognition and signaling pathways of innate immunity, particularly through Toll-like receptors and pattern recognition receptors. It explores the role of these receptors in pathogen recognition, inflammation, antiviral responses, and the regulation of adaptive immunity. The cluster also delves into the molecular mechanisms and mediators involved in innate immune responses.",
    description: This cluster of papers focuses on the recognition and signaling pathways
  "keywords": [
      of innate immunity, particularly through Toll-like receptors and pattern recognition
    "Toll-like Receptors",
      receptors. It explores the role of these receptors in pathogen recognition,
    "Pattern Recognition Receptors",
      inflammation, antiviral responses, and the regulation of adaptive immunity.
     "Inflammation",
      The cluster also delves into the molecular mechanisms and mediators involved
    "Innate Antiviral Responses",
      in innate immune responses.
    "Cytokine-Mediated Link",
     display_name: Innate Immune Recognition and Signaling Pathways
    "Pathogen Recognition",
     domain:
    "NOD-Like Receptors",
      display_name: Life Sciences
    "Endotoxin Hyporesponsiveness",
      id: https://openalex.org/domains/1
    "DAMPs",
     field:
     "Adaptive Immunity Regulation"
      display_name: Immunology and Microbiology
  ],
      id: https://openalex.org/fields/24
  "ids": {
     id: https://openalex.org/T10371
    "openalex": "https://openalex.org/T10371",
     ids:
     "wikipedia": "https://en.wikipedia.org/wiki/Innate_immune_system"
      openalex: https://openalex.org/T10371
  },
      wikipedia: https://en.wikipedia.org/wiki/Innate_immune_system
  "subfield": {
     keywords:
     "id": "https://openalex.org/subfields/2403",
    - Toll-like Receptors
     "display_name": "Immunology"
    - Pattern Recognition Receptors
  },
    - Inflammation
  "field": {
     - Innate Antiviral Responses
    "id": "https://openalex.org/fields/24",
    - Cytokine-Mediated Link
    "display_name": "Immunology and Microbiology"
    - Pathogen Recognition
  },
    - NOD-Like Receptors
  "domain": {
    - Endotoxin Hyporesponsiveness
    "id": "https://openalex.org/domains/1",
    - DAMPs
     "display_name": "Life Sciences"
    - Adaptive Immunity Regulation
  },
    siblings:
  "siblings": [
    - display_name: Genetic Basis of Primary Immunodeficiency Disorders
     {
       id: https://openalex.org/T11725
      "id": "https://openalex.org/T11725",
    - display_name: Human T-cell Leukemia Virus Type 1 Infection
      "display_name": "Genetic Basis of Primary Immunodeficiency Disorders"
       id: https://openalex.org/T12159
    },
    - display_name: Immunobiology of Dendritic Cells
    {
       id: https://openalex.org/T10580
       "id": "https://openalex.org/T12159",
    - display_name: Immunogenicity of Biosimilar Therapeutics in Drug Development
      "display_name": "Human T-cell Leukemia Virus Type 1 Infection"
       id: https://openalex.org/T12255
    },
    - display_name: Immunological Mechanisms in Atherosclerosis Development
    {
       id: https://openalex.org/T12955
       "id": "https://openalex.org/T10580",
    - display_name: Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface
      "display_name": "Immunobiology of Dendritic Cells"
       id: https://openalex.org/T11510
    },
    - display_name: Immunological Responses in Aquatic Organisms
    {
       id: https://openalex.org/T10506
       "id": "https://openalex.org/T12255",
    - display_name: Immunotoxicology in Toxicologic Pathology Research
      "display_name": "Immunogenicity of Biosimilar Therapeutics in Drug Development"
       id: https://openalex.org/T14072
    },
    - display_name: Immunotoxin Therapy for Cancer Treatment
    {
       id: https://openalex.org/T12477
       "id": "https://openalex.org/T12955",
    - display_name: Innate Immunity to Viral Infection
      "display_name": "Immunological Mechanisms in Atherosclerosis Development"
       id: https://openalex.org/T11668
    },
    - display_name: Innate Lymphoid Cells in Immunity
    {
       id: https://openalex.org/T12528
       "id": "https://openalex.org/T11510",
    - display_name: Invertebrate Immunity and Host Defense Mechanisms
      "display_name": "Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface"
       id: https://openalex.org/T11403
    },
    - display_name: Macrophage Activation and Polarization
    {
       id: https://openalex.org/T11313
       "id": "https://openalex.org/T10506",
    - display_name: Mechanisms of Apoptotic Cell Clearance and Immune Regulation
      "display_name": "Immunological Responses in Aquatic Organisms"
       id: https://openalex.org/T12672
    },
    - display_name: Natural Killer Cells in Immunity
    {
       id: https://openalex.org/T11020
       "id": "https://openalex.org/T14072",
    - display_name: Reciprocal Development of TH17 and Treg Cells
      "display_name": "Immunotoxicology in Toxicologic Pathology Research"
       id: https://openalex.org/T10469
    },
    - display_name: Regulatory T Cell Development and Function
    {
       id: https://openalex.org/T10031
       "id": "https://openalex.org/T12477",
    - display_name: Role of Complement System in Immune Response
      "display_name": "Immunotoxin Therapy for Cancer Treatment"
       id: https://openalex.org/T10993
    },
    - display_name: Role of Galectins in Immunity and Disease
    {
       id: https://openalex.org/T12387
       "id": "https://openalex.org/T11668",
    - display_name: Role of Macrophage Migration Inhibitory Factor
      "display_name": "Innate Immunity to Viral Infection"
       id: https://openalex.org/T13254
    },
    - display_name: Role of Mast Cells in Immunoregulation and Disease
    {
       id: https://openalex.org/T11346
       "id": "https://openalex.org/T12528",
    - display_name: Role of Neutrophil Extracellular Traps in Immunity
      "display_name": "Innate Lymphoid Cells in Immunity"
       id: https://openalex.org/T11597
    },
    - display_name: Role of Pentraxins in Innate Immunity and Inflammation
    {
       id: https://openalex.org/T14245
       "id": "https://openalex.org/T11403",
    - display_name: Role of TREM-1 and Endocan in Inflammation
      "display_name": "Invertebrate Immunity and Host Defense Mechanisms"
       id: https://openalex.org/T14165
    },
    - display_name: Trained Immunity in Health and Disease
    {
      id: https://openalex.org/T13410
       "id": "https://openalex.org/T11313",
    subfield:
      "display_name": "Macrophage Activation and Polarization"
      display_name: Immunology
    },
      id: https://openalex.org/subfields/2403
    {
    updated_date: '2024-05-20T05:05:26.879057'
       "id": "https://openalex.org/T12672",
    works_count: 84590
      "display_name": "Mechanisms of Apoptotic Cell Clearance and Immune Regulation"
    },
    {
       "id": "https://openalex.org/T11020",
      "display_name": "Natural Killer Cells in Immunity"
    },
    {
       "id": "https://openalex.org/T10469",
      "display_name": "Reciprocal Development of TH17 and Treg Cells"
    },
    {
       "id": "https://openalex.org/T10031",
      "display_name": "Regulatory T Cell Development and Function"
    },
    {
       "id": "https://openalex.org/T10993",
      "display_name": "Role of Complement System in Immune Response"
    },
    {
       "id": "https://openalex.org/T12387",
      "display_name": "Role of Galectins in Immunity and Disease"
    },
    {
       "id": "https://openalex.org/T13254",
      "display_name": "Role of Macrophage Migration Inhibitory Factor"
    },
    {
       "id": "https://openalex.org/T11346",
      "display_name": "Role of Mast Cells in Immunoregulation and Disease"
    },
    {
       "id": "https://openalex.org/T11597",
      "display_name": "Role of Neutrophil Extracellular Traps in Immunity"
    },
    {
       "id": "https://openalex.org/T14245",
      "display_name": "Role of Pentraxins in Innate Immunity and Inflammation"
    },
    {
       "id": "https://openalex.org/T14165",
      "display_name": "Role of TREM-1 and Endocan in Inflammation"
    },
    {
       "id": "https://openalex.org/T13410",
      "display_name": "Trained Immunity in Health and Disease"
    }
  ],
  "works_count": 84814,
  "cited_by_count": 3027948,
  "updated_date": "2024-08-26T05:50:23.406353",
  "created_date": "2024-01-23"
}
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