Item talk:Q317036

{

 "OpenAlex": {
   "id": "https://openalex.org/T13971",
   "display_name": "Chemistry and Biology of Antitumor Antibiotics",
   "description": "This cluster of papers focuses on the chemistry, biology, and synthesis of antitumor antibiotics, particularly tetrahydroisoquinoline compounds such as Ecteinascidin. It covers topics such as total synthesis, marine-derived compounds, asymmetric synthesis, and DNA binding mechanisms. The research also explores the pharmacological activities and potential clinical utility of these compounds.",
   "keywords": [
     "Tetrahydroisoquinoline",
     "Ecteinascidin",
     "Total Synthesis",
     "Anticancer Drug",
     "Marine-derived Compound",
     "Cycloaddition Reactions",
     "Asymmetric Synthesis",
     "Isocoumarins",
     "Pharmacology",
     "DNA Binding"
   ],
   "ids": {
     "openalex": "https://openalex.org/T13971",
     "wikipedia": "https://en.wikipedia.org/wiki/Tetrahydroisoquinoline_antitumor_antibiotics"
   },
   "subfield": {
     "id": "https://openalex.org/subfields/1306",
     "display_name": "Cancer Research"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "siblings": [
     {
       "id": "https://openalex.org/T11547",
       "display_name": "Biological Activities of Sesquiterpene Lactones in Cancer"
     },
     {
       "id": "https://openalex.org/T13350",
       "display_name": "Biology and Evolution of Myxozoan Parasites"
     },
     {
       "id": "https://openalex.org/T13943",
       "display_name": "Development of Protein Phosphatase Inhibitors as Anticancer Agents"
     },
     {
       "id": "https://openalex.org/T11287",
       "display_name": "Genomic Landscape of Cancer and Mutational Signatures"
     },
     {
       "id": "https://openalex.org/T10433",
       "display_name": "Genotoxicity and Carcinogenesis Mechanisms"
     },
     {
       "id": "https://openalex.org/T12465",
       "display_name": "Lipid Metabolism in Cancer Pathogenesis"
     },
     {
       "id": "https://openalex.org/T10631",
       "display_name": "Metabolic Reprogramming in Cancer Biology"
     },
     {
       "id": "https://openalex.org/T10062",
       "display_name": "MicroRNA Regulation in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10183",
       "display_name": "Molecular Research on Breast Cancer"
     },
     {
       "id": "https://openalex.org/T11591",
       "display_name": "NF-?B Signaling in Inflammation and Cancer"
     },
     {
       "id": "https://openalex.org/T10515",
       "display_name": "Role of Long Noncoding RNAs in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10620",
       "display_name": "Role of Matrix Metalloproteinases in Cancer and Physiology"
     }
   ],
   "works_count": 10482,
   "cited_by_count": 128741,
   "updated_date": "2024-08-26T05:30:42.634750",
   "created_date": "2024-01-23"
 }

}