Item talk:Q300265

{

 "USGS Publications Warehouse": {
   "@context": "https://schema.org",
   "@type": "Article",
   "additionalType": "Journal Article",
   "name": "High doses of corticosteroid suppress resistance to Ichthyophonus in starry flounder",
   "identifier": [
     {
       "@type": "PropertyValue",
       "propertyID": "USGS Publications Warehouse IndexID",
       "value": "70027544",
       "url": "https://pubs.usgs.gov/publication/70027544"
     },
     {
       "@type": "PropertyValue",
       "propertyID": "USGS Publications Warehouse Internal ID",
       "value": 70027544
     },
     {
       "@type": "PropertyValue",
       "propertyID": "DOI",
       "value": "10.1577/H03-056.1",
       "url": "https://doi.org/10.1577/H03-056.1"
     }
   ],
   "journal": {
     "@type": "Periodical",
     "name": "Journal of Aquatic Animal Health",
     "volumeNumber": "16",
     "issueNumber": "1"
   },
   "inLanguage": "en",
   "isPartOf": [
     {
       "@type": "CreativeWorkSeries",
       "name": "Journal of Aquatic Animal Health"
     }
   ],
   "datePublished": "2004",
   "dateModified": "2021-08-30",
   "abstract": "Application of pharmacological doses of the corticosteroid dexamethasone phosphate to starry flounder Platichthys stellatus resulted in a predisposition to clinical ichthyophoniasis and a progression from latent Ichthyophonus infections to patent, histologically identifiable infections. Among Ichthyophonus-challenged starry flounder, the prevalences of clinical infections and histologically identifiable infections were significantly greater in two groups that received dexamethasone (100% and 31%, respectively) than in the respective control groups (8% and 0%). Proliferation of Ichthyophonus infections in corticosteroid-treated groups may have resulted from suppression of the cellular immune response that typically follows corticosteroid application; however, further studies are needed to determine whether these effects occur at lower, physiological concentrations of corticosteroids.",
   "description": "5 p.",
   "publisher": {
     "@type": "Organization",
     "name": "Taylor & Francis Online"
   },
   "author": [
     {
       "@type": "Person",
       "name": "Perry, J.A.",
       "givenName": "J.A.",
       "familyName": "Perry"
     },
     {
       "@type": "Person",
       "name": "Winton, J. R.",
       "givenName": "J. R.",
       "familyName": "Winton",
       "identifier": {
         "@type": "PropertyValue",
         "propertyID": "ORCID",
         "value": "0000-0002-3505-5509",
         "url": "https://orcid.org/0000-0002-3505-5509"
       }
     },
     {
       "@type": "Person",
       "name": "Hershberger, P.K.",
       "givenName": "P.K.",
       "familyName": "Hershberger",
       "identifier": {
         "@type": "PropertyValue",
         "propertyID": "ORCID",
         "value": "0000-0002-2261-7760",
         "url": "https://orcid.org/0000-0002-2261-7760"
       }
     },
     {
       "@type": "Person",
       "name": "Kocan, R. M.",
       "givenName": "R. M.",
       "familyName": "Kocan"
     }
   ],
   "funder": [
     {
       "@type": "Organization",
       "name": "Western Fisheries Research Center",
       "url": "https://www.usgs.gov/centers/western-fisheries-research-center"
     }
   ]
 }

}