Item talk:Q270126
From geokb
{
"USGS Publications Warehouse": { "@context": "https://schema.org", "@type": "Article", "additionalType": "Journal Article", "name": "Drug metabolism in birds", "identifier": [ { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse IndexID", "value": "70195375", "url": "https://pubs.usgs.gov/publication/70195375" }, { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse Internal ID", "value": 70195375 }, { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1159/000137327", "url": "https://doi.org/10.1159/000137327" } ], "journal": { "@type": "Periodical", "name": "Pharmacology", "volumeNumber": "19", "issueNumber": null }, "inLanguage": "en", "isPartOf": [ { "@type": "CreativeWorkSeries", "name": "Pharmacology" } ], "datePublished": "1979", "dateModified": "2018-02-12", "abstract": "Papers published over 100 years since the beginning of the scientific study of drug metabolism in birds were reviewed. Birds were found to be able to accomplish more than 20 general biotransformation reactions in both functionalization and conjugation. Chickens were the primary subject of study but over 30 species of birds were used. Large species differences in drug metabolism exist between birds and mammals as well as between various birds, these differences were mostly quantitative. Qualitative differences were rare. On the whole, drug metabolism studies in birds have been neglected as compared with similar studies on insects and mammals. The uniqueness of birds and the advantages of using birds in drug metabolism studies are discussed. Possible future studies of drug metabolism in birds are recommended.", "description": "5 p.", "publisher": { "@type": "Organization", "name": "Karger" }, "author": [ { "@type": "Person", "name": "Pan, Huo Ping", "givenName": "Huo Ping", "familyName": "Pan" }, { "@type": "Person", "name": "Fouts, James R.", "givenName": "James R.", "familyName": "Fouts" } ] }, "OpenAlex": { "_id": "https://openalex.org/w1975728203", "abstract_inverted_index": { "Papers": [ 0 ], "published": [ 1 ], "over": [ 2, 46 ], "100": [ 3 ], "years": [ 4 ], "since": [ 5 ], "the": [ 6, 9, 40, 80, 104 ], "beginning": [ 7 ], "of": [ 8, 12, 43, 49, 101, 106, 118 ], "scientific": [ 10 ], "study": [ 11, 44 ], "drug": [ 13, 57, 82, 110, 119 ], "metabolism": [ 14, 58, 83, 111, 120 ], "in": [ 15, 33, 56, 85, 109, 121 ], "birds": [ 16, 50, 61, 86, 102, 108, 122 ], "were": [ 17, 20, 39, 51, 72, 77 ], "reviewed.": [ 18 ], "Birds": [ 19 ], "found": [ 21 ], "to": [ 22, 25 ], "be": [ 23 ], "able": [ 24 ], "accomplish": [ 26 ], "more": [ 27 ], "than": [ 28 ], "20": [ 29 ], "general": [ 30 ], "biotransformation": [ 31 ], "reactions": [ 32 ], "both": [ 34 ], "functionalization": [ 35 ], "and": [ 36, 62, 97, 103 ], "conjugation.": [ 37 ], "Chickens": [ 38 ], "primary": [ 41 ], "subject": [ 42 ], "but": [ 45 ], "30": [ 47 ], "species": [ 48, 54 ], "used.": [ 52 ], "Large": [ 53 ], "differences": [ 55, 71, 76 ], "exist": [ 59 ], "between": [ 60, 67 ], "mammals": [ 63 ], "as": [ 64, 66, 90 ], "well": [ 65 ], "various": [ 68 ], "birds,": [ 69 ], "these": [ 70 ], "mostly": [ 73 ], "quantitative.": [ 74 ], "Qualitative": [ 75 ], "rare.": [ 78 ], "On": [ 79 ], "whole,": [ 81 ], "studies": [ 84, 94, 112, 117 ], "have": [ 87 ], "been": [ 88 ], "neglected": [ 89 ], "compared": [ 91 ], "with": [ 92 ], "similar": [ 93 ], "on": [ 95 ], "insects": [ 96 ], "mammals.": [ 98 ], "The": [ 99 ], "uniqueness": [ 100 ], "advantages": [ 105 ], "using": [ 107 ], "are": [ 113, 123 ], "discussed.": [ 114 ], "Possible": [ 115 ], "future": [ 116 ], "recommended.": [ 124 ] }, "apc_list": null, "apc_paid": null, "authorships": [ { "author_position": "first", "author": { "id": "https://openalex.org/A5040406435", "display_name": "Huo Ping Pan", "orcid": null }, "institutions": [ { "id": "https://openalex.org/I4210095140", "display_name": "National Institute of Environmental Health Sciences", "ror": "https://ror.org/00j4k1h63", "country_code": "US", "type": "facility", "lineage": [ "https://openalex.org/I1299022934", "https://openalex.org/I1299303238", "https://openalex.org/I4210095140" ] } ], "countries": [ "US" ], "is_corresponding": true, "raw_author_name": "Huo Ping Pan", "raw_affiliation_strings": [ "Denver Wildlife Research Center, US Fish and Wildlife Service, Denver, Colo., and National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, N.C." ], "affiliations": [ { "raw_affiliation_string": "Denver Wildlife Research Center, US Fish and Wildlife Service, Denver, Colo., and National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, N.C.", "institution_ids": [ "https://openalex.org/I4210095140" ] } ] }, { "author_position": "last", "author": { "id": "https://openalex.org/A5044772461", "display_name": "James R. 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