Item talk:Q258133
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{
"DOI": { "doi": "10.5066/f7sq8xm8", "prefix": "10.5066", "suffix": "f7sq8xm8", "identifiers": [], "alternateIdentifiers": [], "creators": [ { "name": "Work, Thierry M", "nameType": "Personal", "givenName": "Thierry M", "familyName": "Work", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0002-4426-9090", "nameIdentifierScheme": "ORCID" } ] }, { "name": "Dagenais, Julie", "nameType": "Personal", "givenName": "Julie", "familyName": "Dagenais", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0001-5560-9946", "nameIdentifierScheme": "ORCID" } ] }, { "name": "Moeller, Peter D R", "nameType": "Personal", "givenName": "Peter D R", "familyName": "Moeller", "affiliation": [], "nameIdentifiers": [] }, { "name": "Beauchesne, Kevin R", "nameType": "Personal", "givenName": "Kevin R", "familyName": "Beauchesne", "affiliation": [], "nameIdentifiers": [] }, { "name": "Breeden, Renee L", "nameType": "Personal", "givenName": "Renee L", "familyName": "Breeden", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0001-5910-3627", "nameIdentifierScheme": "ORCID" } ] }, { "name": "Rameyer, Robert A", "nameType": "Personal", "givenName": "Robert A", "familyName": "Rameyer", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0002-2145-1746", "nameIdentifierScheme": "ORCID" } ] }, { "name": "Walsh, William J", "nameType": "Personal", "givenName": "William J", "familyName": "Walsh", "affiliation": [], "nameIdentifiers": [] }, { "name": "Abecassis, Melanie", "nameType": "Personal", "givenName": "Melanie", "familyName": "Abecassis", "affiliation": [], "nameIdentifiers": [] }, { "name": "Kobayashi, Donald R", "nameType": "Personal", "givenName": "Donald R", "familyName": "Kobayashi", "affiliation": [], "nameIdentifiers": [] }, { "name": "Conway, Carla M", "nameType": "Personal", "givenName": "Carla M", "familyName": "Conway", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0002-3851-3616", "nameIdentifierScheme": "ORCID" } ] }, { "name": "Winton, James R", "nameType": "Personal", "givenName": "James R", "familyName": "Winton", "affiliation": [], "nameIdentifiers": [ { "schemeUri": "https://orcid.org", "nameIdentifier": "https://orcid.org/0000-0002-3505-5509", "nameIdentifierScheme": "ORCID" } ] } ], "titles": [ { "title": "Pufferfish mortality data" } ], "publisher": "U.S. Geological Survey", "container": {}, "publicationYear": 2017, "subjects": [ { "subject": "Dereplication; tetraodontidae; toxinology; pathology; virology" } ], "contributors": [], "dates": [ { "date": "1999/2014", "dateType": "Collected" }, { "date": "2017", "dateType": "Issued" } ], "language": null, "types": { "ris": "DATA", "bibtex": "misc", "citeproc": "dataset", "schemaOrg": "Dataset", "resourceType": "Dataset", "resourceTypeGeneral": "Dataset" }, "relatedIdentifiers": [ { "relationType": "IsCitedBy", "relatedIdentifier": "10.3354/dao03096", "relatedIdentifierType": "DOI" } ], "relatedItems": [], "sizes": [], "formats": [], "version": null, "rightsList": [], "descriptions": [ { "description": "In 2010, a mass mortality of pufferfish in Hawaii was dominated by Arothron hispidus showing aberrant neurological behaviors. Using pathology, toxinology, and field surveys, we implicated a series of novel, polar, marine toxins as a likely cause of this mass mortality. Our findings are striking in that 1) a marine toxin was associated with a kill of a fish species that is, itself, toxic; 2) we provide a plausible mechanism to explain clinical signs of affected fish, and 3) this epizootic likely depleted puffer populations. Whilst our data are compelling, we did not synthesize the toxin de-novo, we were unable to categorically prove that the polar toxins caused mortality or that they were metabolites of an undefined parent compound. However, our approach does provides a template for marine fish kill investigations associated with marine toxins and inherent limitations of existing methods. Our study also highlights the need for more rapid and cost-effective tools to identify new marine toxins, particularly small, highly polar molecules.", "descriptionType": "Abstract" } ], "geoLocations": [], "fundingReferences": [], "xml": 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}