Item talk:Q251316
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{
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To examine persistence of entire LPAI genome constellations in Alaska, we calculated the genetic identities among 161 full-genome LPAI viruses isolated across 4\u00a0years from five species of duck: northern pintail (Anas acuta), mallard (Anas platyrhynchos), American green-winged teal (Anas crecca), northern shoveler (Anas clypeata) and American wigeon (Anas americana). Based on pairwise genetic distance, highly similar LPAI genomes (>99% identity) were observed within and between species and across a range of geographic distances (up to and >1000\u00a0km), but most often between isolates collected 0\u201310\u00a0km apart. Highly similar viruses were detected between years, suggesting inter-annual persistence, but these were rare in our data set with the majority occurring within 0\u20139\u00a0days of sampling. These results identify LPAI transmission pathways in the context of species, space and time, an initial perspective into the extent of regional virus distribution and persistence, and insight into why no completely Eurasian genomes have ever been detected in Alaska. Such information will be useful in forecasting the movement of foreign-origin avian influenza strains should they be introduced to North America.", "description": "7 p.", "publisher": { "@type": "Organization", "name": "Elsevier" }, "author": [ { "@type": "Person", "name": "Reeves, Andrew B. areeves@usgs.gov", "givenName": "Andrew B.", "familyName": "Reeves", "email": "areeves@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-7526-0726", "url": "https://orcid.org/0000-0002-7526-0726" }, "affiliation": [ { "@type": "Organization", "name": "Alaska Science Center Biology WTEB", "url": "https://www.usgs.gov/centers/alaska-science-center" }, { "@type": "Organization", "name": "Alaska Science Center", "url": "https://www.usgs.gov/centers/alaska-science-center" } ] }, { "@type": "Person", "name": "Pearce, John M. jpearce@usgs.gov", "givenName": "John M.", "familyName": "Pearce", "email": "jpearce@usgs.gov", "identifier": { "@type": 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