Item talk:Q250831
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{
"USGS Publications Warehouse": { "@context": "https://schema.org", "@type": "Article", "additionalType": "Journal Article", "name": "A novel approach reveals that zinc oxide nanoparticles are bioavailable and toxic after dietary exposures", "identifier": [ { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse IndexID", "value": "70036643", "url": "https://pubs.usgs.gov/publication/70036643" }, { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse Internal ID", "value": 70036643 }, { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3109/17435390.2010.501914", "url": "https://doi.org/10.3109/17435390.2010.501914" }, { "@type": "PropertyValue", "propertyID": "ISSN", "value": "17435390" } ], "journal": { "@type": "Periodical", "name": "Nanotoxicology", "volumeNumber": "5", "issueNumber": "1" }, "inLanguage": "en", "isPartOf": [ { "@type": "CreativeWorkSeries", "name": "Nanotoxicology" } ], "datePublished": "2011", "dateModified": "2018-10-10", "abstract": "If engineered nanomaterials are released into the environment, some are likely to end up associated with the food of animals due to aggregation and sorption processes. However, few studies have considered dietary exposure of nanomaterials. Here we show that zinc (Zn) from isotopically modified 67ZnO particles is efficiently assimilated by freshwater snails when ingested with food. The 67Zn from nano-sized 67ZnO appears as bioavailable as 67Zn internalized by diatoms. Apparent agglomeration of the zinc oxide (ZnO) particles did not reduce bioavailability, nor preclude toxicity. In the diet, ZnO nanoparticles damage digestion: snails ate less, defecated less and inefficiently processed the ingested food when exposed to high concentrations of ZnO. It was not clear whether the toxicity was due to the high Zn dose achieved with nanoparticles or to the ZnO nanoparticles themselves. 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