Item talk:Q248498
From geokb
{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Determination of pharmaceutical compounds in surface- and ground-water samples by solid-phase extraction and high-performance liquid chromatography-electrospray ionization mass spectrometry",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70027005",
"url": "https://pubs.usgs.gov/publication/70027005"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70027005
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.chroma.2004.04.005",
"url": "https://doi.org/10.1016/j.chroma.2004.04.005"
},
{
"@type": "PropertyValue",
"propertyID": "ISSN",
"value": "00219673"
}
],
"journal": {
"@type": "Periodical",
"name": "Journal of Chromatography A",
"volumeNumber": "1041",
"issueNumber": "1-2"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Journal of Chromatography A"
}
],
"datePublished": "2004",
"dateModified": "2018-11-14",
"abstract": "Commonly used prescription and over-the-counter pharmaceuticals are possibly present in surface- and ground-water samples at ambient concentrations less than 1 \u03bcg/L. In this report, the performance characteristics of a combined solid-phase extraction isolation and high-performance liquid chromatography\u2013electrospray ionization mass spectrometry (HPLC\u2013ESI-MS) analytical procedure for routine determination of the presence and concentration of human-health pharmaceuticals are described. This method was developed and used in a recent national reconnaissance of pharmaceuticals in USA surface waters. The selection of pharmaceuticals evaluated for this method was based on usage estimates, resulting in a method that contains compounds from diverse chemical classes, which presents challenges and compromises when applied as a single routine analysis. The method performed well for the majority of the 22 pharmaceuticals evaluated, with recoveries greater than 60% for 12 pharmaceuticals. The recoveries of angiotensin-converting enzyme inhibitors, a histamine (H2) receptor antagonist, and antihypoglycemic compound classes were less than 50%, but were retained in the method to provide information describing the potential presence of these compounds in environmental samples and to indicate evidence of possible matrix enhancing effects. Long-term recoveries, evaluated from reagent-water fortifications processed over 2 years, were similar to initial method performance. Method detection limits averaged 0.022 \u03bcg/L, sufficient for expected ambient concentrations. Compound-dependent matrix effects on HPLC/ESI-MS analysis, including enhancement and suppression of ionization, were observed as a 20\u201330% increase in measured concentrations for three compounds and greater than 50% increase for two compounds. Changing internal standard and more frequent ESI source maintenance minimized matrix effects. Application of the method in the national survey demonstrates that several pharmaceuticals are routinely detected at 0.010\u20130.100 \u03bcg/L concentrations.",
"description": "10 p.",
"publisher": {
"@type": "Organization",
"name": "Elsevier"
},
"author": [
{
"@type": "Person",
"name": "Kolpin, D.",
"givenName": "D.",
"familyName": "Kolpin"
},
{
"@type": "Person",
"name": "Anderson, L.G.",
"givenName": "L.G.",
"familyName": "Anderson"
},
{
"@type": "Person",
"name": "Burkhardt, M.R.",
"givenName": "M.R.",
"familyName": "Burkhardt"
},
{
"@type": "Person",
"name": "Cahill, J.D.",
"givenName": "J.D.",
"familyName": "Cahill"
},
{
"@type": "Person",
"name": "Furlong, E. T.",
"givenName": "E. T.",
"familyName": "Furlong",
"identifier": {
"@type": "PropertyValue",
"propertyID": "ORCID",
"value": "0000-0002-7305-4603",
"url": "https://orcid.org/0000-0002-7305-4603"
}
}
],
"funder": [
{
"@type": "Organization",
"name": "Iowa Water Science Center",
"url": "https://www.usgs.gov/centers/cm-water"
},
{
"@type": "Organization",
"name": "Toxic Substances Hydrology Program",
"url": null
}
]
},
"OpenAlex": {
"abstract_inverted_index": {
"Commonly": [
0
],
"used": [
1,
61
],
"prescription": [
2
],
"and": [
3,
11,
33,
49,
60,
100,
140,
167,
211,
227,
238
],
"over-the-counter": [
4
],
"pharmaceuticals": [
5,
53,
68,
76,
119,
258
],
"are": [
6,
54,
259
],
"possibly": [
7
],
"present": [
8
],
"in": [
9,
62,
69,
87,
151,
164,
221,
251
],
"surface-": [
10
],
"ground-water": [
12
],
"samples": [
13,
166
],
"at": [
14,
262
],
"ambient": [
15,
201
],
"concentrations": [
16,
223
],
"less": [
17,
145
],
"than": [
18,
124,
146,
229
],
"1": [
19
],
"microg/L.": [
20
],
"In": [
21
],
"this": [
22,
79
],
"report,": [
23
],
"the": [
24,
47,
114,
117,
152,
158,
249,
252
],
"performance": [
25
],
"characteristics": [
26
],
"of": [
27,
46,
51,
67,
75,
116,
131,
161,
171,
213,
248
],
"a": [
28,
63,
88,
105,
135,
218
],
"combined": [
29
],
"solid-phase": [
30
],
"extraction": [
31
],
"isolation": [
32
],
"high-performance": [
34
],
"liquid": [
35
],
"chromatography-electrospray": [
36
],
"ionization": [
37
],
"mass": [
38
],
"spectrometry": [
39
],
"(HPLC-ESI-MS)": [
40
],
"analytical": [
41
],
"procedure": [
42
],
"for": [
43,
78,
113,
126,
199,
224,
232
],
"routine": [
44,
107
],
"determination": [
45
],
"presence": [
48,
160
],
"concentration": [
50
],
"human-health": [
52
],
"described.": [
55
],
"This": [
56
],
"method": [
57,
80,
89,
110,
153,
190,
250
],
"was": [
58,
81
],
"developed": [
59
],
"recent": [
64
],
"national": [
65,
253
],
"reconnaissance": [
66
],
"USA": [
70
],
"surface": [
71
],
"waters.": [
72
],
"The": [
73,
109,
129
],
"selection": [
74
],
"evaluated": [
77,
178
],
"based": [
82
],
"on": [
83,
206
],
"usage": [
84
],
"estimates,": [
85
],
"resulting": [
86
],
"that": [
90,
256
],
"contains": [
91
],
"compounds": [
92,
163,
226
],
"from": [
93,
179
],
"diverse": [
94
],
"chemical": [
95
],
"classes,": [
96
],
"which": [
97
],
"presents": [
98
],
"challenges": [
99
],
"compromises": [
101
],
"when": [
102
],
"applied": [
103
],
"as": [
104,
217
],
"single": [
106
],
"analysis.": [
108
],
"performed": [
111
],
"well": [
112
],
"majority": [
115
],
"22": [
118
],
"evaluated,": [
120
],
"with": [
121
],
"recoveries": [
122,
130
],
"greater": [
123,
228
],
"60%": [
125
],
"12": [
127
],
"pharmaceuticals.": [
128
],
"angiotensin-converting": [
132
],
"enzyme": [
133
],
"inhibitors,": [
134
],
"histamine": [
136
],
"(H2)": [
137
],
"receptor": [
138
],
"antagonist,": [
139
],
"antihypoglycemic": [
141
],
"compound": [
142
],
"classes": [
143
],
"were": [
144,
149,
186,
215
],
"50%,": [
147
],
"but": [
148
],
"retained": [
150
],
"to": [
154,
168,
188
],
"provide": [
155
],
"information": [
156
],
"describing": [
157
],
"potential": [
159
],
"these": [
162
],
"environmental": [
165
],
"indicate": [
169
],
"evidence": [
170
],
"possible": [
172
],
"matrix": [
173,
204,
245
],
"enhancing": [
174
],
"effects.": [
175,
246
],
"Long-term": [
176
],
"recoveries,": [
177
],
"reagent-water": [
180
],
"fortifications": [
181
],
"processed": [
182
],
"over": [
183
],
"2": [
184
],
"years,": [
185
],
"similar": [
187
],
"initial": [
189
],
"performance.": [
191
],
"Method": [
192
],
"detection": [
193
],
"limits": [
194
],
"averaged": [
195
],
"0.022": [
196
],
"microg/L,": [
197
],
"sufficient": [
198
],
"expected": [
200
],
"concentrations.": [
202,
265
],
"Compound-dependent": [
203
],
"effects": [
205
],
"HPLC/ESI-MS": [
207
],
"analysis,": [
208
],
"including": [
209
],
"enhancement": [
210
],
"suppression": [
212
],
"ionization,": [
214
],
"observed": [
216
],
"20-30%": [
219
],
"increase": [
220,
231
],
"measured": [
222
],
"three": [
225
],
"50%": [
230
],
"two": [
233
],
"compounds.": [
234
],
"Changing": [
235
],
"internal": [
236
],
"standard": [
237
],
"more": [
239
],
"frequent": [
240
],
"ESI": [
241
],
"source": [
242
],
"maintenance": [
243
],
"minimized": [
244
],
"Application": [
247
],
"survey": [
254
],
"demonstrates": [
255
],
"several": [
257
],
"routinely": [
260
],
"detected": [
261
],
"0.010-0.100": [
263
],
"microg/L": [
264
]
},
"apc_list": {
"value": 3490,
"currency": "USD",
"value_usd": 3490,
"provenance": "doaj"
},
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5035434549",
"display_name": "Jeffery D. Cahill",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I2800772125",
"display_name": "Denver Federal Center",
"ror": "https://ror.org/05pxjag90",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1280600231",
"https://openalex.org/I2800772125"
]
},
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Jeffery D Cahill",
"raw_affiliation_strings": [
"National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA",
"institution_ids": [
"https://openalex.org/I2800772125",
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5078395141",
"display_name": "Edward T. Furlong",
"orcid": "https://orcid.org/0000-0002-7305-4603"
},
"institutions": [
{
"id": "https://openalex.org/I2800772125",
"display_name": "Denver Federal Center",
"ror": "https://ror.org/05pxjag90",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1280600231",
"https://openalex.org/I2800772125"
]
},
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Edward T Furlong",
"raw_affiliation_strings": [
"National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA",
"institution_ids": [
"https://openalex.org/I2800772125",
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5059239282",
"display_name": "Mark R. Burkhardt",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I2800772125",
"display_name": "Denver Federal Center",
"ror": "https://ror.org/05pxjag90",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1280600231",
"https://openalex.org/I2800772125"
]
},
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Mark R Burkhardt",
"raw_affiliation_strings": [
"National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA",
"institution_ids": [
"https://openalex.org/I2800772125",
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5059785684",
"display_name": "Dana W. Kolpin",
"orcid": "https://orcid.org/0000-0002-3529-6505"
},
"institutions": [
{
"id": "https://openalex.org/I2800772125",
"display_name": "Denver Federal Center",
"ror": "https://ror.org/05pxjag90",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1280600231",
"https://openalex.org/I2800772125"
]
},
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Dana Kolpin",
"raw_affiliation_strings": [
"National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Water Quality Laboratory, US Geological Survey, P.O. Box 25046, MS 407, Denver Federal Center, Denver, CO 80225-0046, USA",
"institution_ids": [
"https://openalex.org/I2800772125",
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5102460321",
"display_name": "Larry G. Anderson",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I921990950",
"display_name": "University of Colorado Denver",
"ror": "https://ror.org/02hh7en24",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I921990950"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Larry G Anderson",
"raw_affiliation_strings": [
"Department of Chemistry, University of Colorado at Denver, P.O. Box 173364, Denver, CO 80217-3364, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Chemistry, University of Colorado at Denver, P.O. Box 173364, Denver, CO 80217-3364, USA",
"institution_ids": [
"https://openalex.org/I921990950"
]
}
]
}
],
"best_oa_location": null,
"biblio": {
"volume": "1041",
"issue": "1-2",
"first_page": "171",
"last_page": "180"
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2075697329",
"cited_by_count": 300,
"cited_by_percentile_year": {
"min": 98,
"max": 99
},
"concepts": [
{
"id": "https://openalex.org/c185592680",
"wikidata": "https://www.wikidata.org/wiki/Q2329",
"display_name": "Chemistry",
"level": 0,
"score": 0.88614416,
"qid": "Q166089"
},
{
"id": "https://openalex.org/c43617362",
"wikidata": "https://www.wikidata.org/wiki/Q170050",
"display_name": "Chromatography",
"level": 1,
"score": 0.8442464,
"qid": "Q158809"
},
{
"id": "https://openalex.org/c162356407",
"wikidata": "https://www.wikidata.org/wiki/Q180809",
"display_name": "Mass spectrometry",
"level": 2,
"score": 0.6638826,
"qid": null
},
{
"id": "https://openalex.org/c40684141",
"wikidata": "https://www.wikidata.org/wiki/Q902061",
"display_name": "Electrospray ionization",
"level": 3,
"score": 0.65927815,
"qid": null
},
{
"id": "https://openalex.org/c179998833",
"wikidata": "https://www.wikidata.org/wiki/Q381233",
"display_name": "High-performance liquid chromatography",
"level": 2,
"score": 0.6460501,
"qid": null
},
{
"id": "https://openalex.org/c81426234",
"wikidata": "https://www.wikidata.org/wiki/Q1408763",
"display_name": "Solid phase extraction",
"level": 3,
"score": 0.62407964,
"qid": null
},
{
"id": "https://openalex.org/c4725764",
"wikidata": "https://www.wikidata.org/wiki/Q844704",
"display_name": "Extraction (chemistry)",
"level": 2,
"score": 0.5558725,
"qid": null
},
{
"id": "https://openalex.org/c194451485",
"wikidata": "https://www.wikidata.org/wiki/Q1327575",
"display_name": "Electrospray",
"level": 3,
"score": 0.5098633,
"qid": null
},
{
"id": "https://openalex.org/c106487976",
"wikidata": "https://www.wikidata.org/wiki/Q685816",
"display_name": "Matrix (chemical analysis)",
"level": 2,
"score": 0.48101813,
"qid": null
},
{
"id": "https://openalex.org/c175467004",
"wikidata": "https://www.wikidata.org/wiki/Q17088083",
"display_name": "Ion suppression in liquid chromatography\u2013mass spectrometry",
"level": 4,
"score": 0.46086323,
"qid": null
},
{
"id": "https://openalex.org/c64489805",
"wikidata": "https://www.wikidata.org/wiki/Q873864",
"display_name": "Liquid chromatography\u2013mass spectrometry",
"level": 3,
"score": 0.37882078,
"qid": null
}
],
"corresponding_author_ids": [],
"corresponding_institution_ids": [],
"countries_distinct_count": 1,
"counts_by_year": [
{
"year": 2024,
"cited_by_count": 4
},
{
"year": 2023,
"cited_by_count": 3
},
{
"year": 2022,
"cited_by_count": 10
},
{
"year": 2021,
"cited_by_count": 5
},
{
"year": 2020,
"cited_by_count": 4
},
{
"year": 2019,
"cited_by_count": 15
},
{
"year": 2018,
"cited_by_count": 9
},
{
"year": 2017,
"cited_by_count": 12
},
{
"year": 2016,
"cited_by_count": 14
},
{
"year": 2015,
"cited_by_count": 18
},
{
"year": 2014,
"cited_by_count": 12
},
{
"year": 2013,
"cited_by_count": 15
},
{
"year": 2012,
"cited_by_count": 17
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Determination of pharmaceutical compounds in surface- and ground-water samples by solid-phase extraction and high-performance liquid chromatography\u2013electrospray ionization mass spectrometry",
"doi": "https://doi.org/10.1016/j.chroma.2004.04.005",
"fwci": 21.749,
"grants": [],
"has_fulltext": false,
"id": "https://openalex.org/W2075697329",
"ids": {
"openalex": "https://openalex.org/W2075697329",
"doi": "https://doi.org/10.1016/j.chroma.2004.04.005",
"mag": "2075697329",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/15281266"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 3,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/solid-phase-extraction",
"display_name": "Solid phase extraction",
"score": 0.62407964
},
{
"id": "https://openalex.org/keywords/solid-phase-microextraction",
"display_name": "Solid-Phase Microextraction",
"score": 0.555298
},
{
"id": "https://openalex.org/keywords/sample-preparation-techniques",
"display_name": "Sample Preparation Techniques",
"score": 0.536939
},
{
"id": "https://openalex.org/keywords/dispersive-liquid-liquid-microextraction",
"display_name": "Dispersive Liquid-Liquid Microextraction",
"score": 0.514964
},
{
"id": "https://openalex.org/keywords/matrix",
"display_name": "Matrix (chemical analysis)",
"score": 0.48101813
}
],
"language": "en",
"locations": [
{
"is_oa": false,
"landing_page_url": "https://doi.org/10.1016/j.chroma.2004.04.005",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S176136234",
"display_name": "Journal of Chromatography A",
"issn_l": "0021-9673",
"issn": [
"0021-9673",
"1873-3778"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320990",
"host_organization_name": "Elsevier BV",
"host_organization_lineage": [
"https://openalex.org/P4310320990"
],
"host_organization_lineage_names": [
"Elsevier BV"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/15281266",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 2,
"mesh": [
{
"descriptor_ui": "D002851",
"descriptor_name": "Chromatography, High Pressure Liquid",
"qualifier_ui": "Q000379",
"qualifier_name": "methods",
"is_major_topic": true
},
{
"descriptor_ui": "D004364",
"descriptor_name": "Pharmaceutical Preparations",
"qualifier_ui": "Q000032",
"qualifier_name": "analysis",
"is_major_topic": true
},
{
"descriptor_ui": "D021241",
"descriptor_name": "Spectrometry, Mass, Electrospray Ionization",
"qualifier_ui": "Q000379",
"qualifier_name": "methods",
"is_major_topic": true
},
{
"descriptor_ui": "D014874",
"descriptor_name": "Water Pollutants, Chemical",
"qualifier_ui": "Q000032",
"qualifier_name": "analysis",
"is_major_topic": true
},
{
"descriptor_ui": "D002138",
"descriptor_name": "Calibration",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D002851",
"descriptor_name": "Chromatography, High Pressure Liquid",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D004364",
"descriptor_name": "Pharmaceutical Preparations",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D012015",
"descriptor_name": "Reference Standards",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D012680",
"descriptor_name": "Sensitivity and Specificity",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D021241",
"descriptor_name": "Spectrometry, Mass, Electrospray Ionization",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D014874",
"descriptor_name": "Water Pollutants, Chemical",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2075697329/ngrams",
"open_access": {
"is_oa": false,
"oa_status": "closed",
"oa_url": null,
"any_repository_has_fulltext": false
},
"primary_location": {
"is_oa": false,
"landing_page_url": "https://doi.org/10.1016/j.chroma.2004.04.005",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S176136234",
"display_name": "Journal of Chromatography A",
"issn_l": "0021-9673",
"issn": [
"0021-9673",
"1873-3778"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320990",
"host_organization_name": "Elsevier BV",
"host_organization_lineage": [
"https://openalex.org/P4310320990"
],
"host_organization_lineage_names": [
"Elsevier BV"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
"primary_topic": {
"id": "https://openalex.org/T10419",
"display_name": "Antibiotic Resistance in Aquatic Environments and Wastewater",
"score": 0.9999,
"subfield": {
"id": "https://openalex.org/subfields/2310",
"display_name": "Pollution"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
"publication_date": "2004-07-01",
"publication_year": 2004,
"referenced_works": [
"https://openalex.org/W1994221839",
"https://openalex.org/W2007745329",
"https://openalex.org/W2028960822",
"https://openalex.org/W2029593210",
"https://openalex.org/W2029716971",
"https://openalex.org/W2037766564",
"https://openalex.org/W2039218749",
"https://openalex.org/W2050808694",
"https://openalex.org/W2054615569",
"https://openalex.org/W2061188578",
"https://openalex.org/W2070239831",
"https://openalex.org/W4236662324",
"https://openalex.org/W4252367938"
],
"referenced_works_count": 13,
"related_works": [
"https://openalex.org/W4200544467",
"https://openalex.org/W2608736974",
"https://openalex.org/W2556850201",
"https://openalex.org/W2155907787",
"https://openalex.org/W2126902475",
"https://openalex.org/W2041651069",
"https://openalex.org/W2022873267",
"https://openalex.org/W2007390411",
"https://openalex.org/W1993721378",
"https://openalex.org/W1978258542"
],
"sustainable_development_goals": [
{
"id": "https://metadata.un.org/sdg/6",
"score": 0.7,
"display_name": "Clean water and sanitation"
}
],
"title": "Determination of pharmaceutical compounds in surface- and ground-water samples by solid-phase extraction and high-performance liquid chromatography\u2013electrospray ionization mass spectrometry",
"topics": [
{
"id": "https://openalex.org/T10419",
"display_name": "Antibiotic Resistance in Aquatic Environments and Wastewater",
"score": 0.9999,
"subfield": {
"id": "https://openalex.org/subfields/2310",
"display_name": "Pollution"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T10180",
"display_name": "Analytical Chemistry Techniques",
"score": 0.9985,
"subfield": {
"id": "https://openalex.org/subfields/1602",
"display_name": "Analytical Chemistry"
},
"field": {
"id": "https://openalex.org/fields/16",
"display_name": "Chemistry"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T13338",
"display_name": "Effects of Beta-Adrenergic Agonists in Livestock",
"score": 0.9973,
"subfield": {
"id": "https://openalex.org/subfields/1103",
"display_name": "Animal Science and Zoology"
},
"field": {
"id": "https://openalex.org/fields/11",
"display_name": "Agricultural and Biological Sciences"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-08T05:39:27.645984",
"versions": [],
"qid": null
}
}
