Item talk:Q247861
From geokb
{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Nodeomics: Pathogen detection in vertebrate lymph nodes using meta-transcriptomics",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70044084",
"url": "https://pubs.usgs.gov/publication/70044084"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70044084
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1371/journal.pone.0013432",
"url": "https://doi.org/10.1371/journal.pone.0013432"
}
],
"journal": {
"@type": "Periodical",
"name": "PLoS",
"volumeNumber": "5",
"issueNumber": "10"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "PLoS"
}
],
"datePublished": "2010",
"dateModified": "2018-10-22",
"abstract": "The ongoing emergence of human infections originating from wildlife highlights the need for better knowledge of the microbial community in wildlife species where traditional diagnostic approaches are limited. Here we evaluate the microbial biota in healthy mule deer (Odocoileus hemionus) by analyses of lymph node meta-transcriptomes. cDNA libraries from five individuals and two pools of samples were prepared from retropharyngeal lymph node RNA enriched for polyadenylated RNA and sequenced using Roche-454 Life Sciences technology. Protein-coding and 16S ribosomal RNA (rRNA) sequences were taxonomically profiled using protein and rRNA specific databases. Representatives of all bacterial phyla were detected in the seven libraries based on protein-coding transcripts indicating that viable microbiota were present in lymph nodes. Residents of skin and rumen, and those ubiquitous in mule deer habitat dominated classifiable bacterial species. Based on detection of both rRNA and protein-coding transcripts, we identified two new proteobacterial species; a Helicobacter closely related to Helicobacter cetorum in the Helicobacter pylori/Helicobacter acinonychis complex and an Acinetobacter related to Acinetobacter schindleri. Among viruses, a novel gamma retrovirus and other members of the Poxviridae and Retroviridae were identified. We additionally evaluated bacterial diversity by amplicon sequencing the hypervariable V6 region of 16S rRNA and demonstrate that overall taxonomic diversity is higher with the meta-transcriptomic approach. These data provide the most complete picture to date of the microbial diversity within a wildlife host. Our research advances the use of meta-transcriptomics to study microbiota in wildlife tissues, which will facilitate detection of novel organisms with pathogenic potential to human and animals.",
"description": "e13432; 10 p.",
"publisher": {
"@type": "Organization",
"name": "PloS"
},
"author": [
{
"@type": "Person",
"name": "Cross, Paul C. pcross@usgs.gov",
"givenName": "Paul C.",
"familyName": "Cross",
"email": "pcross@usgs.gov",
"identifier": {
"@type": "PropertyValue",
"propertyID": "ORCID",
"value": "0000-0001-8045-5213",
"url": "https://orcid.org/0000-0001-8045-5213"
},
"affiliation": [
{
"@type": "Organization",
"name": "Northern Rocky Mountain Science Center",
"url": "https://www.usgs.gov/centers/norock"
}
]
},
{
"@type": "Person",
"name": "Padhi, Abinash",
"givenName": "Abinash",
"familyName": "Padhi"
},
{
"@type": "Person",
"name": "Qi, Ji",
"givenName": "Ji",
"familyName": "Qi"
},
{
"@type": "Person",
"name": "Schuster, Stephan C.",
"givenName": "Stephan C.",
"familyName": "Schuster"
},
{
"@type": "Person",
"name": "Tomsho, Lynn P.",
"givenName": "Lynn P.",
"familyName": "Tomsho"
},
{
"@type": "Person",
"name": "Wittekindt, Nicola E.",
"givenName": "Nicola E.",
"familyName": "Wittekindt"
},
{
"@type": "Person",
"name": "Poss, Mary",
"givenName": "Mary",
"familyName": "Poss"
},
{
"@type": "Person",
"name": "Kasson, Lindsay R.",
"givenName": "Lindsay R.",
"familyName": "Kasson"
},
{
"@type": "Person",
"name": "Packard, Michael",
"givenName": "Michael",
"familyName": "Packard"
},
{
"@type": "Person",
"name": "Zhao, Fangqing",
"givenName": "Fangqing",
"familyName": "Zhao"
}
],
"funder": [
{
"@type": "Organization",
"name": "Northern Rocky Mountain Science Center",
"url": "https://www.usgs.gov/centers/norock"
},
{
"@type": "Organization",
"name": "Contaminant Biology Program",
"url": null
}
]
},
"OpenAlex": {
"abstract_inverted_index": {
"The": [
0
],
"ongoing": [
1
],
"emergence": [
2
],
"of": [
3,
15,
42,
54,
91,
115,
133,
174,
193,
217,
230,
242
],
"human": [
4,
249
],
"infections": [
5
],
"originating": [
6
],
"from": [
7,
48,
58
],
"wildlife": [
8,
20,
223,
236
],
"highlights": [
9
],
"the": [
10,
16,
31,
98,
153,
175,
189,
205,
211,
218,
228
],
"need": [
11
],
"for": [
12,
64
],
"better": [
13
],
"knowledge": [
14
],
"microbial": [
17,
32,
219
],
"community": [
18
],
"in": [
19,
34,
97,
111,
122,
152,
235
],
"species": [
21
],
"where": [
22
],
"traditional": [
23
],
"diagnostic": [
24
],
"approaches": [
25
],
"are": [
26
],
"limited.": [
27
],
"Here": [
28
],
"we": [
29,
139
],
"evaluate": [
30
],
"biota": [
33
],
"healthy": [
35
],
"mule": [
36,
123
],
"deer": [
37,
124
],
"(Odocoileus": [
38
],
"hemionus)": [
39
],
"by": [
40,
186
],
"analyses": [
41
],
"lymph": [
43,
60,
112
],
"node": [
44,
61
],
"meta-transcriptomes.": [
45
],
"cDNA": [
46
],
"libraries": [
47,
100
],
"five": [
49
],
"individuals": [
50
],
"and": [
51,
67,
75,
86,
117,
119,
136,
158,
171,
177,
196,
250
],
"two": [
52,
141
],
"pools": [
53
],
"samples": [
55
],
"were": [
56,
81,
95,
109,
179
],
"prepared": [
57
],
"retropharyngeal": [
59
],
"RNA": [
62,
66,
78
],
"enriched": [
63
],
"polyadenylated": [
65
],
"sequenced": [
68
],
"using": [
69,
84
],
"Roche-454": [
70
],
"Life": [
71
],
"Sciences": [
72
],
"technology.": [
73
],
"Protein-coding": [
74
],
"16S": [
76,
194
],
"ribosomal": [
77
],
"(rRNA)": [
79
],
"sequences": [
80
],
"taxonomically": [
82
],
"profiled": [
83
],
"protein": [
85
],
"rRNA": [
87,
135,
195
],
"specific": [
88
],
"databases.": [
89
],
"Representatives": [
90
],
"all": [
92
],
"bacterial": [
93,
128,
184
],
"phyla": [
94
],
"detected": [
96
],
"seven": [
99
],
"based": [
101
],
"on": [
102,
131
],
"protein-coding": [
103,
137
],
"transcripts": [
104
],
"indicating": [
105
],
"that": [
106,
198
],
"viable": [
107
],
"microbiota": [
108,
234
],
"present": [
110
],
"nodes.": [
113
],
"Residents": [
114
],
"skin": [
116
],
"rumen,": [
118
],
"those": [
120
],
"ubiquitous": [
121
],
"habitat": [
125
],
"dominated": [
126
],
"classifiable": [
127
],
"species.": [
129
],
"Based": [
130
],
"detection": [
132,
241
],
"both": [
134
],
"transcripts,": [
138
],
"identified": [
140
],
"new": [
142
],
"proteobacterial": [
143
],
"species;": [
144
],
"a": [
145,
167,
222
],
"Helicobacter": [
146,
150,
154
],
"closely": [
147
],
"related": [
148,
161
],
"to": [
149,
162,
215,
232,
248
],
"cetorum": [
151
],
"pylori/Helicobacter": [
155
],
"acinonychis": [
156
],
"complex": [
157
],
"an": [
159
],
"Acinetobacter": [
160,
163
],
"schindleri.": [
164
],
"Among": [
165
],
"viruses,": [
166
],
"novel": [
168,
243
],
"gamma": [
169
],
"retrovirus": [
170
],
"other": [
172
],
"members": [
173
],
"Poxviridae": [
176
],
"Retroviridae": [
178
],
"identified.": [
180
],
"We": [
181
],
"additionally": [
182
],
"evaluated": [
183
],
"diversity": [
185,
201,
220
],
"amplicon": [
187
],
"sequencing": [
188
],
"hypervariable": [
190
],
"V6": [
191
],
"region": [
192
],
"demonstrate": [
197
],
"overall": [
199
],
"taxonomic": [
200
],
"is": [
202
],
"higher": [
203
],
"with": [
204,
245
],
"meta-transcriptomic": [
206
],
"approach.": [
207
],
"These": [
208
],
"data": [
209
],
"provide": [
210
],
"most": [
212
],
"complete": [
213
],
"picture": [
214
],
"date": [
216
],
"within": [
221
],
"host.": [
224
],
"Our": [
225
],
"research": [
226
],
"advances": [
227
],
"use": [
229
],
"meta-transcriptomics": [
231
],
"study": [
233
],
"tissues,": [
237
],
"which": [
238
],
"will": [
239
],
"facilitate": [
240
],
"organisms": [
244
],
"pathogenic": [
246
],
"potential": [
247
],
"animals.": [
251
]
},
"apc_list": {
"value": 1805,
"currency": "USD",
"value_usd": 1805,
"provenance": "doaj"
},
"apc_paid": {
"value": 1805,
"currency": "USD",
"value_usd": 1805,
"provenance": "doaj"
},
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5001912779",
"display_name": "Nicola E. Wittekindt",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Nicola E. Wittekindt",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5021230130",
"display_name": "Abinash Padhi",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
},
{
"id": "https://openalex.org/I1338678786",
"display_name": "Center for Disease Dynamics, Economics & Policy",
"ror": "https://ror.org/01skhd946",
"country_code": "US",
"type": "nonprofit",
"lineage": [
"https://openalex.org/I1338678786"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Abinash Padhi",
"raw_affiliation_strings": [
"Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515",
"https://openalex.org/I1338678786"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5088865524",
"display_name": "Stephan C. Schuster",
"orcid": "https://orcid.org/0000-0001-9082-7527"
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
},
{
"id": "https://openalex.org/I1338678786",
"display_name": "Center for Disease Dynamics, Economics & Policy",
"ror": "https://ror.org/01skhd946",
"country_code": "US",
"type": "nonprofit",
"lineage": [
"https://openalex.org/I1338678786"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Stephan C. Schuster",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
},
{
"raw_affiliation_string": "Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I1338678786"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5013747025",
"display_name": "Ji Qi",
"orcid": "https://orcid.org/0000-0001-9732-3145"
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Ji Qi",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5087698339",
"display_name": "Fangqing Zhao",
"orcid": "https://orcid.org/0000-0002-6216-1235"
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Fangqing Zhao",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5106035917",
"display_name": "Lynn P. Tomsho",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Lynn P. Tomsho",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5058583975",
"display_name": "Lindsay R. Kasson",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Lindsay R. Kasson",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5080450470",
"display_name": "Michael Packard",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Michael Packard",
"raw_affiliation_strings": [
"Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biochemistry and Molecular Biology, Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I130769515"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5055904582",
"display_name": "Paul C. Cross",
"orcid": "https://orcid.org/0000-0001-8045-5213"
},
"institutions": [
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Paul Cross",
"raw_affiliation_strings": [
"Northern Rocky Mountain Science Center, U.S. Geological Survey, Bozeman, Montana, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Northern Rocky Mountain Science Center, U.S. Geological Survey, Bozeman, Montana, United States of America",
"institution_ids": [
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5080238858",
"display_name": "Mary Poss",
"orcid": "https://orcid.org/0000-0003-4147-2410"
},
"institutions": [
{
"id": "https://openalex.org/I1338678786",
"display_name": "Center for Disease Dynamics, Economics & Policy",
"ror": "https://ror.org/01skhd946",
"country_code": "US",
"type": "nonprofit",
"lineage": [
"https://openalex.org/I1338678786"
]
},
{
"id": "https://openalex.org/I130769515",
"display_name": "Pennsylvania State University",
"ror": "https://ror.org/04p491231",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I130769515"
]
},
{
"id": "https://openalex.org/I874236823",
"display_name": "Fogarty International Center",
"ror": "https://ror.org/02xey9a22",
"country_code": "US",
"type": "healthcare",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1299303238",
"https://openalex.org/I874236823"
]
},
{
"id": "https://openalex.org/I1299303238",
"display_name": "National Institutes of Health",
"ror": "https://ror.org/01cwqze88",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1299303238"
]
}
],
"countries": [
"US"
],
"is_corresponding": true,
"raw_author_name": "Mary Poss",
"raw_affiliation_strings": [
"Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America"
],
"affiliations": [
{
"raw_affiliation_string": "Department of Biology, Center for Infectious Disease Dynamics, The Pennsylvania State University, University Park, Pennsylvania, United States of America",
"institution_ids": [
"https://openalex.org/I1338678786",
"https://openalex.org/I130769515"
]
},
{
"raw_affiliation_string": "Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America",
"institution_ids": [
"https://openalex.org/I874236823",
"https://openalex.org/I1299303238"
]
}
]
}
],
"best_oa_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.1371/journal.pone.0013432",
"pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013432&type=printable",
"source": {
"id": "https://openalex.org/S202381698",
"display_name": "PLoS ONE",
"issn_l": "1932-6203",
"issn": [
"1932-6203"
],
"is_oa": true,
"is_in_doaj": true,
"is_core": true,
"host_organization": "https://openalex.org/P4310315706",
"host_organization_name": "Public Library of Science",
"host_organization_lineage": [
"https://openalex.org/P4310315706"
],
"host_organization_lineage_names": [
"Public Library of Science"
],
"type": "journal"
},
"license": "cc-by",
"license_id": "https://openalex.org/licenses/cc-by",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"biblio": {
"volume": "5",
"issue": "10",
"first_page": "e13432",
"last_page": "e13432"
},
"citation_normalized_percentile": {
"value": 0.787655,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2055804073",
"cited_by_count": 36,
"cited_by_percentile_year": {
"min": 93,
"max": 94
},
"concepts": [
{
"id": "https://openalex.org/C86803240",
"wikidata": "https://www.wikidata.org/wiki/Q420",
"display_name": "Biology",
"level": 0,
"score": 0.82500196
},
{
"id": "https://openalex.org/C15151743",
"wikidata": "https://www.wikidata.org/wiki/Q903778",
"display_name": "Metagenomics",
"level": 3,
"score": 0.71907455
},
{
"id": "https://openalex.org/C67905577",
"wikidata": "https://www.wikidata.org/wiki/Q215980",
"display_name": "Ribosomal RNA",
"level": 3,
"score": 0.5974299
},
{
"id": "https://openalex.org/C162317418",
"wikidata": "https://www.wikidata.org/wiki/Q252857",
"display_name": "Transcriptome",
"level": 4,
"score": 0.49308226
},
{
"id": "https://openalex.org/C143121216",
"wikidata": "https://www.wikidata.org/wiki/Q1330402",
"display_name": "Microbiome",
"level": 2,
"score": 0.44150865
},
{
"id": "https://openalex.org/C54355233",
"wikidata": "https://www.wikidata.org/wiki/Q7162",
"display_name": "Genetics",
"level": 1,
"score": 0.38009474
},
{
"id": "https://openalex.org/C70721500",
"wikidata": "https://www.wikidata.org/wiki/Q177005",
"display_name": "Computational biology",
"level": 1,
"score": 0.3724702
},
{
"id": "https://openalex.org/C89423630",
"wikidata": "https://www.wikidata.org/wiki/Q7193",
"display_name": "Microbiology",
"level": 1,
"score": 0.33418322
},
{
"id": "https://openalex.org/C104317684",
"wikidata": "https://www.wikidata.org/wiki/Q7187",
"display_name": "Gene",
"level": 2,
"score": 0.20395267
},
{
"id": "https://openalex.org/C150194340",
"wikidata": "https://www.wikidata.org/wiki/Q26972",
"display_name": "Gene expression",
"level": 3,
"score": 0.0894807
}
],
"corresponding_author_ids": [
"https://openalex.org/A5080238858"
],
"corresponding_institution_ids": [
"https://openalex.org/I1338678786",
"https://openalex.org/I130769515",
"https://openalex.org/I874236823",
"https://openalex.org/I1299303238"
],
"countries_distinct_count": 1,
"counts_by_year": [
{
"year": 2022,
"cited_by_count": 1
},
{
"year": 2020,
"cited_by_count": 1
},
{
"year": 2019,
"cited_by_count": 2
},
{
"year": 2017,
"cited_by_count": 2
},
{
"year": 2015,
"cited_by_count": 5
},
{
"year": 2014,
"cited_by_count": 4
},
{
"year": 2013,
"cited_by_count": 4
},
{
"year": 2012,
"cited_by_count": 2
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Nodeomics: Pathogen Detection in Vertebrate Lymph Nodes Using Meta-Transcriptomics",
"doi": "https://doi.org/10.1371/journal.pone.0013432",
"fulltext_origin": "pdf",
"fwci": 2.563,
"grants": [],
"has_fulltext": true,
"id": "https://openalex.org/W2055804073",
"ids": {
"openalex": "https://openalex.org/W2055804073",
"doi": "https://doi.org/10.1371/journal.pone.0013432",
"mag": "2055804073",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/20976145",
"pmcid": "https://www.ncbi.nlm.nih.gov/pmc/articles/2956653"
},
"indexed_in": [
"crossref",
"doaj",
"pubmed"
],
"institutions_distinct_count": 5,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/microbiome",
"display_name": "Microbiome",
"score": 0.489268
}
],
"language": "en",
"locations": [
{
"is_oa": true,
"landing_page_url": "https://doi.org/10.1371/journal.pone.0013432",
"pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013432&type=printable",
"source": {
"id": "https://openalex.org/S202381698",
"display_name": "PLoS ONE",
"issn_l": "1932-6203",
"issn": [
"1932-6203"
],
"is_oa": true,
"is_in_doaj": true,
"is_core": true,
"host_organization": "https://openalex.org/P4310315706",
"host_organization_name": "Public Library of Science",
"host_organization_lineage": [
"https://openalex.org/P4310315706"
],
"host_organization_lineage_names": [
"Public Library of Science"
],
"type": "journal"
},
"license": "cc-by",
"license_id": "https://openalex.org/licenses/cc-by",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": false,
"landing_page_url": "https://doaj.org/article/21865c0a7bee4e8ba4f09dcaa52404dc",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306401280",
"display_name": "DOAJ (DOAJ: Directory of Open Access Journals)",
"issn_l": null,
"issn": null,
"is_oa": true,
"is_in_doaj": false,
"is_core": false,
"host_organization": null,
"host_organization_name": null,
"host_organization_lineage": [],
"host_organization_lineage_names": [],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
{
"is_oa": true,
"landing_page_url": "https://europepmc.org/articles/pmc2956653",
"pdf_url": "https://europepmc.org/articles/pmc2956653?pdf=render",
"source": {
"id": "https://openalex.org/S4306400806",
"display_name": "Europe PMC (PubMed Central)",
"issn_l": null,
"issn": null,
"is_oa": true,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1303153112",
"host_organization_name": "European Bioinformatics Institute",
"host_organization_lineage": [
"https://openalex.org/I1303153112"
],
"host_organization_lineage_names": [
"European Bioinformatics Institute"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": true,
"landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956653",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S2764455111",
"display_name": "PubMed Central",
"issn_l": null,
"issn": null,
"is_oa": true,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/20976145",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 5,
"mesh": [
{
"descriptor_ui": "D003670",
"descriptor_name": "Deer",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": true
},
{
"descriptor_ui": "D020869",
"descriptor_name": "Gene Expression Profiling",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D008198",
"descriptor_name": "Lymph Nodes",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": true
},
{
"descriptor_ui": "D000818",
"descriptor_name": "Animals",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D003670",
"descriptor_name": "Deer",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D008198",
"descriptor_name": "Lymph Nodes",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2055804073/ngrams",
"open_access": {
"is_oa": true,
"oa_status": "gold",
"oa_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013432&type=printable",
"any_repository_has_fulltext": true
},
"primary_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.1371/journal.pone.0013432",
"pdf_url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013432&type=printable",
"source": {
"id": "https://openalex.org/S202381698",
"display_name": "PLoS ONE",
"issn_l": "1932-6203",
"issn": [
"1932-6203"
],
"is_oa": true,
"is_in_doaj": true,
"is_core": true,
"host_organization": "https://openalex.org/P4310315706",
"host_organization_name": "Public Library of Science",
"host_organization_lineage": [
"https://openalex.org/P4310315706"
],
"host_organization_lineage_names": [
"Public Library of Science"
],
"type": "journal"
},
"license": "cc-by",
"license_id": "https://openalex.org/licenses/cc-by",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"primary_topic": {
"id": "https://openalex.org/T11048",
"display_name": "Ecology and Evolution of Viruses in Ecosystems",
"score": 0.9969,
"subfield": {
"id": "https://openalex.org/subfields/2303",
"display_name": "Ecology"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
"publication_date": "2010-10-18",
"publication_year": 2010,
"referenced_works": [
"https://openalex.org/W1525014224",
"https://openalex.org/W1826726928",
"https://openalex.org/W1858169744",
"https://openalex.org/W1978647329",
"https://openalex.org/W1989171740",
"https://openalex.org/W1989889539",
"https://openalex.org/W1998601670",
"https://openalex.org/W2001031283",
"https://openalex.org/W2017529960",
"https://openalex.org/W2017815194",
"https://openalex.org/W2018420111",
"https://openalex.org/W2032526902",
"https://openalex.org/W2032604387",
"https://openalex.org/W2037269076",
"https://openalex.org/W2041924403",
"https://openalex.org/W2047774330",
"https://openalex.org/W2050065329",
"https://openalex.org/W2058322671",
"https://openalex.org/W2066596168",
"https://openalex.org/W2071272846",
"https://openalex.org/W2071501400",
"https://openalex.org/W2072515653",
"https://openalex.org/W2075623226",
"https://openalex.org/W2082928585",
"https://openalex.org/W2093891969",
"https://openalex.org/W2095538538",
"https://openalex.org/W2103546861",
"https://openalex.org/W2113601822",
"https://openalex.org/W2114548104",
"https://openalex.org/W2115085883",
"https://openalex.org/W2116895571",
"https://openalex.org/W2117522399",
"https://openalex.org/W2119125910",
"https://openalex.org/W2120645726",
"https://openalex.org/W2121859555",
"https://openalex.org/W2122719918",
"https://openalex.org/W2125755185",
"https://openalex.org/W2126567810",
"https://openalex.org/W2126809954",
"https://openalex.org/W2127435093",
"https://openalex.org/W2133508358",
"https://openalex.org/W2133840661",
"https://openalex.org/W2134061616",
"https://openalex.org/W2134661094",
"https://openalex.org/W2139122528",
"https://openalex.org/W2139270639",
"https://openalex.org/W2141561400",
"https://openalex.org/W2145336165",
"https://openalex.org/W2145933466",
"https://openalex.org/W2149573313",
"https://openalex.org/W2149735614",
"https://openalex.org/W2150891147",
"https://openalex.org/W2152885278",
"https://openalex.org/W2155066423",
"https://openalex.org/W2155367962",
"https://openalex.org/W2156748860",
"https://openalex.org/W2159104379",
"https://openalex.org/W2164800904",
"https://openalex.org/W2170027074",
"https://openalex.org/W2170149594",
"https://openalex.org/W2170398996",
"https://openalex.org/W2170881661",
"https://openalex.org/W25206051"
],
"referenced_works_count": 63,
"related_works": [
"https://openalex.org/W4297131566",
"https://openalex.org/W3195915274",
"https://openalex.org/W3158976456",
"https://openalex.org/W3156493549",
"https://openalex.org/W3139084279",
"https://openalex.org/W2474302342",
"https://openalex.org/W2210738511",
"https://openalex.org/W2080583581",
"https://openalex.org/W2017364432",
"https://openalex.org/W1910109602"
],
"sustainable_development_goals": [
{
"id": "https://metadata.un.org/sdg/15",
"score": 0.63,
"display_name": "Life on land"
}
],
"title": "Nodeomics: Pathogen Detection in Vertebrate Lymph Nodes Using Meta-Transcriptomics",
"topics": [
{
"id": "https://openalex.org/T11048",
"display_name": "Ecology and Evolution of Viruses in Ecosystems",
"score": 0.9969,
"subfield": {
"id": "https://openalex.org/subfields/2303",
"display_name": "Ecology"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T13220",
"display_name": "Mycoviruses in Fungal Symbiosis and Pathogenesis",
"score": 0.9964,
"subfield": {
"id": "https://openalex.org/subfields/1310",
"display_name": "Endocrinology"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
{
"id": "https://openalex.org/T10976",
"display_name": "Gastrointestinal Viral Infections and Vaccines Development",
"score": 0.9917,
"subfield": {
"id": "https://openalex.org/subfields/2725",
"display_name": "Infectious Diseases"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-14T07:42:32.314933",
"versions": []
}
}
