Item talk:Q236620
From geokb
{
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Although apparently not pathogenic in their reservoir hosts, some viruses from bats severely affect other mammals, including humans. Examples include severe acute respiratory syndrome coronaviruses, Ebola and Marburg viruses, and Nipah and Hendra viruses. Factors underlying high viral diversity in bats are the subject of speculation. We hypothesize that flight, a factor common to all bats but to no other mammals, provides an intensive selective force for coexistence with viral parasites through a daily cycle that elevates metabolism and body temperature analogous to the febrile response in other mammals. On an evolutionary scale, this host\u2013virus interaction might have resulted in the large diversity of zoonotic viruses in bats, possibly through bat viruses adapting to be more tolerant of the fever response and less virulent to their natural hosts.", "description": "5 p.", "publisher": { "@type": "Organization", "name": "Centers for Disease Control and Prevention" }, "author": [ { "@type": "Person", "name": "O'Shea, Thomas J. osheat@usgs.gov", "givenName": "Thomas J.", "familyName": "O'Shea", "email": "osheat@usgs.gov", "affiliation": [ { "@type": "Organization", "name": "Fort Collins Science Center", "url": "https://www.usgs.gov/centers/fort-collins-science-center" } ] }, { "@type": "Person", "name": "Cunningham, Andrew A.", "givenName": "Andrew A.", "familyName": "Cunningham" }, { "@type": "Person", "name": "Peel, Alison J.", "givenName": "Alison J.", "familyName": "Peel" }, { "@type": "Person", "name": "Plowright, Raina K.", "givenName": "Raina K.", "familyName": "Plowright" }, { "@type": "Person", "name": "Hayman, David T.S.", "givenName": "David T.S.", "familyName": "Hayman" }, { "@type": "Person", "name": "Fooks, Anthony R.", "givenName": "Anthony R.", "familyName": "Fooks" }, { "@type": "Person", "name": "Luis, Angela D.", "givenName": "Angela D.", "familyName": "Luis" }, { "@type": "Person", "name": "Wood, James L.N.", "givenName": "James L.N.", "familyName": "Wood" }, { "@type": "Person", "name": "Cryan, Paul M.", "givenName": "Paul M.", "familyName": "Cryan", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-2915-8894", "url": "https://orcid.org/0000-0002-2915-8894" }, "affiliation": [ { "@type": "Organization", "name": "Fort Collins Science Center", "url": "https://www.usgs.gov/centers/fort-collins-science-center" } ] } ], "funder": [ { "@type": "Organization", "name": "Fort Collins Science Center", "url": "https://www.usgs.gov/centers/fort-collins-science-center" } ] }, "OpenAlex": { "abstract_inverted_index": { "Abstract": [ 0 ], "Bats": [ 1 ], "are": [ 2, 54 ], "sources": [ 3 ], "of": [ 4, 57, 116, 130 ], "high": [ 5, 49 ], "viral": [ 6, 50, 82 ], "diversity": [ 7, 51, 115 ], "and": [ 8, 39, 42, 44, 91, 134 ], "high-profile": [ 9 ], "zoonotic": [ 10, 117 ], "viruses": [ 11, 22, 118, 124 ], "worldwide.": [ 12 ], "Although": [ 13 ], "apparently": [ 14 ], "not": [ 15 ], "pathogenic": [ 16 ], "in": [ 17, 52, 99, 112, 119 ], "their": [ 18, 138 ], "reservoir": [ 19 ], "hosts,": [ 20 ], "some": [ 21 ], "from": [ 23 ], "bats": [ 24, 53, 68 ], "severely": [ 25 ], "affect": [ 26 ], "other": [ 27, 72, 100 ], "mammals,": [ 28, 73 ], "including": [ 29 ], "humans.": [ 30 ], "Examples": [ 31 ], "include": [ 32 ], "severe": [ 33 ], "acute": [ 34 ], "respiratory": [ 35 ], "syndrome": [ 36 ], "coronaviruses,": [ 37 ], "Ebola": [ 38 ], "Marburg": [ 40 ], "viruses,": [ 41 ], "Nipah": [ 43 ], "Hendra": [ 45 ], "viruses.": [ 46 ], "Factors": [ 47 ], "underlying": [ 48 ], "the": [ 55, 96, 113, 131 ], "subject": [ 56 ], "speculation.": [ 58 ], "We": [ 59 ], "hypothesize": [ 60 ], "that": [ 61, 88 ], "flight,": [ 62 ], "a": [ 63, 85 ], "factor": [ 64 ], "common": [ 65 ], "to": [ 66, 70, 95, 126, 137 ], "all": [ 67 ], "but": [ 69 ], "no": [ 71 ], "provides": [ 74 ], "an": [ 75, 103 ], "intensive": [ 76 ], "selective": [ 77 ], "force": [ 78 ], "for": [ 79 ], "coexistence": [ 80 ], "with": [ 81 ], "parasites": [ 83 ], "through": [ 84, 122 ], "daily": [ 86 ], "cycle": [ 87 ], "elevates": [ 89 ], "metabolism": [ 90 ], "body": [ 92 ], "temperature": [ 93 ], "analogous": [ 94 ], "febrile": [ 97 ], "response": [ 98, 133 ], "mammals.": [ 101 ], "On": [ 102 ], "evolutionary": [ 104 ], "scale,": [ 105 ], "this": [ 106 ], "host\u2013virus": [ 107 ], "interaction": [ 108 ], "might": [ 109 ], "have": [ 110 ], "resulted": [ 111 ], "large": [ 114 ], "bats,": [ 120 ], "possibly": [ 121 ], "bat": [ 123 ], "adapting": [ 125 ], "be": [ 127 ], "more": [ 128 ], "tolerant": [ 129 ], "fever": [ 132 ], "less": [ 135 ], "virulent": [ 136 ], "natural": [ 139 ], "hosts.": [ 140 ] }, "apc_list": { "value": 0, "currency": "USD", "value_usd": 0, "provenance": "doaj" }, "apc_paid": null, "authorships": [ { "author_position": "first", "author": { "id": "https://openalex.org/A5103514893", "display_name": "Thomas J. 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