Item talk:Q235516
From geokb
{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Mortality and kidney histopathology of Chinook salmon Oncorhynchus tshawytscha exposed to virulent and attenuated Renibacterium salmoninarum strains",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70170490",
"url": "https://pubs.usgs.gov/publication/70170490"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70170490
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3354/dao043199",
"url": "https://doi.org/10.3354/dao043199"
}
],
"journal": {
"@type": "Periodical",
"name": "Diseases of Aquatic Organisms",
"volumeNumber": "43",
"issueNumber": "3"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Diseases of Aquatic Organisms"
}
],
"datePublished": "2001",
"dateModified": "2016-04-21",
"abstract": "An isolate of Renibacterium salmoninarum (strain MT 239) exhibiting reduced virulence in rainbow trout Oncorhynchus mykiss was tested for its ability to cause bacterial kidney disease (BKD) in chinook salmon Oncorhynchus tshawytscha, a salmonid species more susceptible to BKD. Juvenile chinook salmon were exposed to either 33209, the American Type Culture Collection type strain of R. salmoninarum, or to MT 239, by an intraperitoneal injection of 1 x 10(3) or 1 x 10(6) bacteria fish(-1), or by a 24 h immersion in 1 x 10(5) or 1 x 10(7) bacteria ml(-1). For 22 wk fish were held in 12 degrees C water and monitored for mortality. Fish were sampled periodically for histological examination of kidney tissues. In contrast to fish exposed to the high dose of strain 33209 by either injection or immersion, none of the fish exposed to strain MT 239 by either route exhibited gross clinical signs or histopathological changes indicative of BKD. However, the MT 239 strain was detected by the direct fluorescent antibody technique in 4 fish that died up to 11 wk after the injection challenge and in 5 fish that died up to 20 wk after the immersion challenge. Viable MT 239 was isolated in culture from 3 fish that died up to 13 wk after the immersion challenge. Total mortality in groups injected with the high dose of strain MT 239 (12%) was also significantly lower (p < 0.05) than mortality in groups injected with strain 33209 (73 %). These data indicate that the attenuated virulence observed with MT 239 in rainbow trout also occurs in a salmonid species highly susceptible to BKD. The reasons for the attenuated virulence of MT 239 were not determined but may be related to the reduced levels of the putative virulence protein p57 associated with this strain.",
"description": "11 p.",
"publisher": {
"@type": "Organization",
"name": "Inter-Research"
},
"author": [
{
"@type": "Person",
"name": "O'Farrell, Caroline L.",
"givenName": "Caroline L.",
"familyName": "O'Farrell",
"affiliation": [
{
"@type": "Organization",
"name": "Western Fisheries Research Center",
"url": "https://www.usgs.gov/centers/western-fisheries-research-center"
}
]
},
{
"@type": "Person",
"name": "Elliott, Diane G. dgelliott@usgs.gov",
"givenName": "Diane G.",
"familyName": "Elliott",
"email": "dgelliott@usgs.gov",
"identifier": {
"@type": "PropertyValue",
"propertyID": "ORCID",
"value": "0000-0002-4809-6692",
"url": "https://orcid.org/0000-0002-4809-6692"
},
"affiliation": [
{
"@type": "Organization",
"name": "Western Fisheries Research Center",
"url": "https://www.usgs.gov/centers/western-fisheries-research-center"
}
]
},
{
"@type": "Person",
"name": "Landolt, Marsha L.",
"givenName": "Marsha L.",
"familyName": "Landolt"
}
],
"funder": [
{
"@type": "Organization",
"name": "Western Fisheries Research Center",
"url": "https://www.usgs.gov/centers/western-fisheries-research-center"
}
]
},
"OpenAlex": {
"abstract_inverted_index": {
"DAO": [
0,
24,
437
],
"Diseases": [
1
],
"of": [
2,
33,
56,
59,
109,
161,
172,
218,
230,
239,
258,
329,
380,
394
],
"Aquatic": [
3
],
"Organisms": [
4
],
"Contact": [
5
],
"the": [
6,
22,
154,
227,
240,
261,
268,
283,
297,
317,
326,
354,
377,
391,
395
],
"journal": [
7
],
"Facebook": [
8,
428
],
"Twitter": [
9
],
"RSS": [
10,
426
],
"Mailing": [
11
],
"List": [
12
],
"Subscribe": [
13
],
"to": [
14,
39,
128,
144,
151,
165,
223,
226,
243,
279,
293,
313,
372,
390
],
"our": [
15
],
"mailing": [
16
],
"list": [
17
],
"via": [
18
],
"Mailchimp": [
19
],
"HomeLatest": [
20
],
"VolumeAbout": [
21
],
"JournalEditorsSpecials": [
23
],
"43:199-209": [
25
],
"(2000)": [
26
],
"-": [
27,
427,
429,
431
],
"doi:10.3354/dao043199": [
28
],
"Mortality": [
29
],
"and": [
30,
41,
207,
286
],
"kidney": [
31,
131,
219
],
"histopathology": [
32
],
"chinook": [
34,
135,
147
],
"salmon": [
35,
136,
148
],
"Oncorhynchus": [
36,
121,
137
],
"tshawytscha": [
37
],
"exposed": [
38,
150,
225,
242
],
"virulent": [
40
],
"attenuated": [
42,
355,
378
],
"Renibacterium": [
43,
110,
406
],
"salmoninarum": [
44,
111,
407
],
"strains": [
45
],
"Caroline": [
46
],
"L.": [
47,
53
],
"O\u00b9Farrell1,2,*,": [
48
],
"Diane": [
49
],
"G.": [
50
],
"Elliott2,**,": [
51
],
"Marsha": [
52
],
"Landolt1": [
54
],
"1School": [
55
],
"Fisheries,": [
57
],
"University": [
58
],
"Washington,": [
60
],
"Seattle,": [
61,
80
],
"Washington": [
62,
81
],
"98195,": [
63
],
"USA": [
64,
83
],
"2Western": [
65
],
"Fisheries": [
66
],
"Research": [
67
],
"Center,": [
68
],
"Biological": [
69
],
"Resources": [
70
],
"Division,": [
71
],
"United": [
72
],
"States": [
73
],
"Geological": [
74
],
"Survey,": [
75
],
"6505": [
76
],
"N.E.": [
77
],
"65th": [
78
],
"Street,": [
79
],
"98115,": [
82
],
"*Present": [
84
],
"address:": [
85
],
"Institut": [
86
],
"National": [
87
],
"de": [
88,
93
],
"la": [
89
],
"Recherche": [
90
],
"Agronomique,": [
91
],
"Unit\u00e9": [
92
],
"Virologie": [
94
],
"et": [
95
],
"Immunologie": [
96
],
"Mol\u00e9culaires,": [
97
],
"78352": [
98
],
"Jouy-en-Josas": [
99
],
"cedex,": [
100
],
"France": [
101
],
"**Corresponding": [
102
],
"author.": [
103
],
"E-mail:": [
104
],
"diane_elliott@usgs.gov": [
105
],
"ABSTRACT:": [
106
],
"An": [
107
],
"isolate": [
108
],
"(strain": [
112
],
"MT": [
113,
166,
245,
262,
301,
331,
359,
381
],
"239)": [
114
],
"exhibiting": [
115
],
"reduced": [
116,
392
],
"virulence": [
117,
356,
379,
397
],
"in": [
118,
134,
188,
204,
273,
287,
305,
322,
343,
361,
366,
421,
436
],
"rainbow": [
119,
362
],
"trout": [
120,
363
],
"mykiss": [
122
],
"was": [
123,
265,
303,
334
],
"tested": [
124
],
"for": [
125,
209,
215,
376
],
"its": [
126
],
"ability": [
127
],
"cause": [
129
],
"bacterial": [
130
],
"disease": [
132
],
"(BKD)": [
133
],
"tshawytscha,": [
138
],
"a": [
139,
184,
367
],
"salmonid": [
140,
368
],
"species": [
141,
369
],
"more": [
142
],
"susceptible": [
143,
371
],
"BKD.": [
145,
259,
373
],
"Juvenile": [
146
],
"were": [
149,
202,
212,
383
],
"either": [
152,
234,
248
],
"33209,": [
153
],
"American": [
155
],
"Type": [
156
],
"Culture": [
157
],
"Collection": [
158
],
"type": [
159
],
"strain": [
160,
231,
244,
264,
330,
347,
410
],
"R.": [
162
],
"salmoninarum,": [
163
],
"or": [
164,
176,
182,
192,
236,
254
],
"239,": [
167
],
"by": [
168,
183,
233,
247,
267,
434
],
"an": [
169
],
"intraperitoneal": [
170
],
"injection": [
171,
235,
284
],
"1": [
173,
177,
189,
193
],
"\u00d7": [
174
],
"103": [
175
],
"x": [
178,
190,
194
],
"106": [
179
],
"bacteria": [
180,
196
],
"fish-1,": [
181
],
"24": [
185
],
"h": [
186
],
"immersion": [
187,
298,
318
],
"105": [
191
],
"107": [
195
],
"ml-1.": [
197
],
"For": [
198
],
"22": [
199
],
"wk": [
200,
281,
295,
315
],
"fish": [
201,
224,
241,
275,
289,
309
],
"held": [
203
],
"12\u00b0C": [
205
],
"water": [
206
],
"monitored": [
208
],
"mortality.": [
210
],
"Fish": [
211
],
"sampled": [
213
],
"periodically": [
214
],
"histological": [
216
],
"examination": [
217
],
"tissues.": [
220
],
"In": [
221
],
"contrast": [
222
],
"high": [
228,
327
],
"dose": [
229,
328
],
"33209": [
232,
348
],
"immersion,": [
237
],
"none": [
238
],
"239": [
246,
263,
302,
332,
360,
382
],
"route": [
249
],
"exhibited": [
250
],
"gross": [
251
],
"clinical": [
252
],
"signs": [
253
],
"histopathological": [
255
],
"changes": [
256
],
"indicative": [
257
],
"However,": [
260
],
"detected": [
266
],
"direct": [
269
],
"fluorescent": [
270
],
"antibody": [
271
],
"technique": [
272
],
"4": [
274
],
"that": [
276,
290,
310,
353
],
"died": [
277,
291,
311
],
"up": [
278,
292,
312
],
"11": [
280
],
"after": [
282,
296,
316
],
"challenge": [
285
],
"5": [
288
],
"20": [
294
],
"challenge.": [
299,
319
],
"Viable": [
300
],
"isolated": [
304
],
"culture": [
306
],
"from": [
307
],
"3": [
308
],
"13": [
314
],
"Total": [
320
],
"mortality": [
321,
342
],
"groups": [
323,
344
],
"injected": [
324,
345
],
"with": [
325,
346,
358,
401
],
"(12%)": [
333
],
"also": [
335,
364
],
"significantly": [
336
],
"lower": [
337
],
"(p": [
338
],
"<": [
339
],
"0.05)": [
340
],
"than": [
341
],
"(73%).": [
349
],
"These": [
350
],
"data": [
351
],
"indicate": [
352
],
"observed": [
357
],
"occurs": [
365
],
"highly": [
370
],
"The": [
374
],
"reasons": [
375
],
"not": [
384
],
"determined": [
385
],
"but": [
386
],
"may": [
387
],
"be": [
388
],
"related": [
389
],
"levels": [
393
],
"putative": [
396
],
"protein": [
398
],
"p57": [
399,
414
],
"associated": [
400
],
"this": [
402
],
"strain.": [
403
],
"KEY": [
404
],
"WORDS:": [
405
],
"\u00b7": [
408,
411,
413,
415,
417
],
"Attenuated": [
409
],
"Pathogenesis": [
412
],
"Histopathology": [
416
],
"BKD": [
418
],
"Full": [
419
],
"text": [
420
],
"pdf": [
422
],
"format": [
423
],
"PreviousNextExport": [
424
],
"citation": [
425
],
"Tweet": [
430
],
"linkedIn": [
432
],
"Cited": [
433
],
"Published": [
435
],
"Vol.": [
438
],
"43,": [
439
],
"No.": [
440
],
"3.": [
441
],
"Online": [
442,
451
],
"publication": [
443
],
"date:": [
444
],
"December": [
445
],
"21,": [
446
],
"2000": [
447,
456
],
"Print": [
448
],
"ISSN:": [
449,
452
],
"0177-5103;": [
450
],
"1616-1580": [
453
],
"Copyright": [
454
],
"\u00a9": [
455
],
"Inter-Research.": [
457
]
},
"apc_list": null,
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5044976542",
"display_name": "CL O'Farrell",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I201448701",
"display_name": "University of Washington",
"ror": "https://ror.org/00cvxb145",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I201448701"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "CL O'Farrell",
"raw_affiliation_strings": [
"School of Fisheries, University of Washington, Seattle 98195, USA."
],
"affiliations": [
{
"raw_affiliation_string": "School of Fisheries, University of Washington, Seattle 98195, USA.",
"institution_ids": [
"https://openalex.org/I201448701"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5077168798",
"display_name": "D.C. Elliott",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "DG Elliott",
"raw_affiliation_strings": [
"United States Geological Survey"
],
"affiliations": [
{
"raw_affiliation_string": "United States Geological Survey",
"institution_ids": [
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5054460447",
"display_name": "Marsha L. Landolt",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I201448701",
"display_name": "University of Washington",
"ror": "https://ror.org/00cvxb145",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I201448701"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "ML Landolt",
"raw_affiliation_strings": [
"School of Fisheries, University of Washington, Seattle, Washington 98195, USA"
],
"affiliations": [
{
"raw_affiliation_string": "School of Fisheries, University of Washington, Seattle, Washington 98195, USA",
"institution_ids": [
"https://openalex.org/I201448701"
]
}
]
}
],
"best_oa_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.3354/dao043199",
"pdf_url": "https://www.int-res.com/articles/dao/43/d043p199.pdf",
"source": {
"id": "https://openalex.org/S49731288",
"display_name": "Diseases of Aquatic Organisms",
"issn_l": "0177-5103",
"issn": [
"0177-5103",
"1616-1580"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310313773",
"host_organization_name": "Inter-Research",
"host_organization_lineage": [
"https://openalex.org/P4310313773"
],
"host_organization_lineage_names": [
"Inter-Research"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"biblio": {
"volume": "43",
"issue": null,
"first_page": "199",
"last_page": "209"
},
"citation_normalized_percentile": {
"value": 0.708867,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2024457724",
"cited_by_count": 25,
"cited_by_percentile_year": {
"min": 87,
"max": 88
},
"concepts": [
{
"id": "https://openalex.org/C2779140988",
"wikidata": "https://www.wikidata.org/wiki/Q133325",
"display_name": "Oncorhynchus",
"level": 3,
"score": 0.89883757
},
{
"id": "https://openalex.org/C86803240",
"wikidata": "https://www.wikidata.org/wiki/Q420",
"display_name": "Biology",
"level": 0,
"score": 0.72966766
},
{
"id": "https://openalex.org/C100398564",
"wikidata": "https://www.wikidata.org/wiki/Q898845",
"display_name": "Chinook wind",
"level": 4,
"score": 0.6863019
},
{
"id": "https://openalex.org/C89423630",
"wikidata": "https://www.wikidata.org/wiki/Q7193",
"display_name": "Microbiology",
"level": 1,
"score": 0.51865524
},
{
"id": "https://openalex.org/C60987743",
"wikidata": "https://www.wikidata.org/wiki/Q1460232",
"display_name": "Virulence",
"level": 3,
"score": 0.5007739
},
{
"id": "https://openalex.org/C2994167347",
"wikidata": "https://www.wikidata.org/wiki/Q187986",
"display_name": "Rainbow trout",
"level": 3,
"score": 0.4283985
},
{
"id": "https://openalex.org/C42972112",
"wikidata": "https://www.wikidata.org/wiki/Q170201",
"display_name": "Veterinary medicine",
"level": 1,
"score": 0.37285882
},
{
"id": "https://openalex.org/C505870484",
"wikidata": "https://www.wikidata.org/wiki/Q180538",
"display_name": "Fishery",
"level": 1,
"score": 0.29354864
},
{
"id": "https://openalex.org/C2909208804",
"wikidata": "https://www.wikidata.org/wiki/Q127282",
"display_name": "Fish <Actinopterygii>",
"level": 2,
"score": 0.18867391
},
{
"id": "https://openalex.org/C71924100",
"wikidata": "https://www.wikidata.org/wiki/Q11190",
"display_name": "Medicine",
"level": 0,
"score": 0.06372139
},
{
"id": "https://openalex.org/C55493867",
"wikidata": "https://www.wikidata.org/wiki/Q7094",
"display_name": "Biochemistry",
"level": 1,
"score": 0.0
},
{
"id": "https://openalex.org/C104317684",
"wikidata": "https://www.wikidata.org/wiki/Q7187",
"display_name": "Gene",
"level": 2,
"score": 0.0
}
],
"corresponding_author_ids": [],
"corresponding_institution_ids": [],
"countries_distinct_count": 1,
"counts_by_year": [
{
"year": 2023,
"cited_by_count": 1
},
{
"year": 2022,
"cited_by_count": 4
},
{
"year": 2020,
"cited_by_count": 1
},
{
"year": 2014,
"cited_by_count": 1
},
{
"year": 2013,
"cited_by_count": 2
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Mortality and kidney histopathology of chinook salmon Oncorhynchus tshawytscha exposed to virulent and attenuated Renibacterium salmoninarum strains",
"doi": "https://doi.org/10.3354/dao043199",
"fwci": 0.6,
"grants": [],
"has_fulltext": false,
"id": "https://openalex.org/W2024457724",
"ids": {
"openalex": "https://openalex.org/W2024457724",
"doi": "https://doi.org/10.3354/dao043199",
"mag": "2024457724",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/11206735"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 2,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/chinook-wind",
"display_name": "Chinook wind",
"score": 0.6863019
},
{
"id": "https://openalex.org/keywords/fish-immunology",
"display_name": "Fish Immunology",
"score": 0.499389
}
],
"language": "en",
"locations": [
{
"is_oa": true,
"landing_page_url": "https://doi.org/10.3354/dao043199",
"pdf_url": "https://www.int-res.com/articles/dao/43/d043p199.pdf",
"source": {
"id": "https://openalex.org/S49731288",
"display_name": "Diseases of Aquatic Organisms",
"issn_l": "0177-5103",
"issn": [
"0177-5103",
"1616-1580"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310313773",
"host_organization_name": "Inter-Research",
"host_organization_lineage": [
"https://openalex.org/P4310313773"
],
"host_organization_lineage_names": [
"Inter-Research"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/11206735",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 2,
"mesh": [
{
"descriptor_ui": "D005393",
"descriptor_name": "Fish Diseases",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": true
},
{
"descriptor_ui": "D006094",
"descriptor_name": "Gram-Positive Bacteria",
"qualifier_ui": "Q000472",
"qualifier_name": "pathogenicity",
"is_major_topic": true
},
{
"descriptor_ui": "D016908",
"descriptor_name": "Gram-Positive Bacterial Infections",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": true
},
{
"descriptor_ui": "D007674",
"descriptor_name": "Kidney Diseases",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": true
},
{
"descriptor_ui": "D012474",
"descriptor_name": "Salmon",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D000818",
"descriptor_name": "Animals",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D017931",
"descriptor_name": "DNA Primers",
"qualifier_ui": "Q000737",
"qualifier_name": "chemistry",
"is_major_topic": false
},
{
"descriptor_ui": "D017931",
"descriptor_name": "DNA Primers",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D004269",
"descriptor_name": "DNA, Bacterial",
"qualifier_ui": "Q000737",
"qualifier_name": "chemistry",
"is_major_topic": false
},
{
"descriptor_ui": "D004269",
"descriptor_name": "DNA, Bacterial",
"qualifier_ui": "Q000302",
"qualifier_name": "isolation & purification",
"is_major_topic": false
},
{
"descriptor_ui": "D004269",
"descriptor_name": "DNA, Bacterial",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D005260",
"descriptor_name": "Female",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D005393",
"descriptor_name": "Fish Diseases",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D019085",
"descriptor_name": "Fluorescent Antibody Technique, Direct",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D019085",
"descriptor_name": "Fluorescent Antibody Technique, Direct",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D019084",
"descriptor_name": "Fluorescent Antibody Technique, Indirect",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D019084",
"descriptor_name": "Fluorescent Antibody Technique, Indirect",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D006094",
"descriptor_name": "Gram-Positive Bacteria",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D006094",
"descriptor_name": "Gram-Positive Bacteria",
"qualifier_ui": "Q000254",
"qualifier_name": "growth & development",
"is_major_topic": false
},
{
"descriptor_ui": "D006094",
"descriptor_name": "Gram-Positive Bacteria",
"qualifier_ui": "Q000235",
"qualifier_name": "genetics",
"is_major_topic": false
},
{
"descriptor_ui": "D006094",
"descriptor_name": "Gram-Positive Bacteria",
"qualifier_ui": "Q000737",
"qualifier_name": "chemistry",
"is_major_topic": false
},
{
"descriptor_ui": "D016908",
"descriptor_name": "Gram-Positive Bacterial Infections",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": false
},
{
"descriptor_ui": "D016908",
"descriptor_name": "Gram-Positive Bacterial Infections",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D006651",
"descriptor_name": "Histocytochemistry",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D006651",
"descriptor_name": "Histocytochemistry",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D007101",
"descriptor_name": "Immersion",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D007274",
"descriptor_name": "Injections, Intraperitoneal",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D007274",
"descriptor_name": "Injections, Intraperitoneal",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D007668",
"descriptor_name": "Kidney",
"qualifier_ui": "Q000473",
"qualifier_name": "pathology",
"is_major_topic": false
},
{
"descriptor_ui": "D007668",
"descriptor_name": "Kidney",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": false
},
{
"descriptor_ui": "D007668",
"descriptor_name": "Kidney",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D007674",
"descriptor_name": "Kidney Diseases",
"qualifier_ui": "Q000382",
"qualifier_name": "microbiology",
"is_major_topic": false
},
{
"descriptor_ui": "D007674",
"descriptor_name": "Kidney Diseases",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D008297",
"descriptor_name": "Male",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D016133",
"descriptor_name": "Polymerase Chain Reaction",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D016133",
"descriptor_name": "Polymerase Chain Reaction",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D014774",
"descriptor_name": "Virulence",
"qualifier_ui": "Q000235",
"qualifier_name": "genetics",
"is_major_topic": false
},
{
"descriptor_ui": "D014774",
"descriptor_name": "Virulence",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2024457724/ngrams",
"open_access": {
"is_oa": true,
"oa_status": "bronze",
"oa_url": "https://www.int-res.com/articles/dao/43/d043p199.pdf",
"any_repository_has_fulltext": false
},
"primary_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.3354/dao043199",
"pdf_url": "https://www.int-res.com/articles/dao/43/d043p199.pdf",
"source": {
"id": "https://openalex.org/S49731288",
"display_name": "Diseases of Aquatic Organisms",
"issn_l": "0177-5103",
"issn": [
"0177-5103",
"1616-1580"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310313773",
"host_organization_name": "Inter-Research",
"host_organization_lineage": [
"https://openalex.org/P4310313773"
],
"host_organization_lineage_names": [
"Inter-Research"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"primary_topic": {
"id": "https://openalex.org/T10506",
"display_name": "Immunological Responses in Aquatic Organisms",
"score": 0.9998,
"subfield": {
"id": "https://openalex.org/subfields/2403",
"display_name": "Immunology"
},
"field": {
"id": "https://openalex.org/fields/24",
"display_name": "Immunology and Microbiology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
"publication_date": "2000-01-01",
"publication_year": 2000,
"referenced_works": [
"https://openalex.org/W1518869860",
"https://openalex.org/W1585894",
"https://openalex.org/W1967149697",
"https://openalex.org/W1972395036",
"https://openalex.org/W1980629379",
"https://openalex.org/W1995924221",
"https://openalex.org/W1997574377",
"https://openalex.org/W2007804559",
"https://openalex.org/W2008629332",
"https://openalex.org/W2018101372",
"https://openalex.org/W2022746769",
"https://openalex.org/W2023380487",
"https://openalex.org/W2024557364",
"https://openalex.org/W2025388277",
"https://openalex.org/W2026423999",
"https://openalex.org/W2032908301",
"https://openalex.org/W2037325046",
"https://openalex.org/W2037473604",
"https://openalex.org/W2051471670",
"https://openalex.org/W2053365717",
"https://openalex.org/W2055621551",
"https://openalex.org/W2056942403",
"https://openalex.org/W2060286053",
"https://openalex.org/W2060763343",
"https://openalex.org/W2061794117",
"https://openalex.org/W2063385900",
"https://openalex.org/W2065086551",
"https://openalex.org/W2066239483",
"https://openalex.org/W2068170677",
"https://openalex.org/W2077389818",
"https://openalex.org/W2079699153",
"https://openalex.org/W2089426862",
"https://openalex.org/W2090447176",
"https://openalex.org/W2098174650",
"https://openalex.org/W2121073072",
"https://openalex.org/W2126909406",
"https://openalex.org/W2127579584",
"https://openalex.org/W2152807658",
"https://openalex.org/W2317198665",
"https://openalex.org/W30406402",
"https://openalex.org/W312465972",
"https://openalex.org/W4238559580",
"https://openalex.org/W4239138948",
"https://openalex.org/W4250364377",
"https://openalex.org/W644780381"
],
"referenced_works_count": 45,
"related_works": [
"https://openalex.org/W4235814682",
"https://openalex.org/W4234469100",
"https://openalex.org/W3029131242",
"https://openalex.org/W281236044",
"https://openalex.org/W2341545969",
"https://openalex.org/W2323464699",
"https://openalex.org/W2117057540",
"https://openalex.org/W2092631797",
"https://openalex.org/W2022058006",
"https://openalex.org/W1966941729"
],
"sustainable_development_goals": [
{
"display_name": "Life below water",
"id": "https://metadata.un.org/sdg/14",
"score": 0.75
}
],
"title": "Mortality and kidney histopathology of chinook salmon Oncorhynchus tshawytscha exposed to virulent and attenuated Renibacterium salmoninarum strains",
"topics": [
{
"id": "https://openalex.org/T10506",
"display_name": "Immunological Responses in Aquatic Organisms",
"score": 0.9998,
"subfield": {
"id": "https://openalex.org/subfields/2403",
"display_name": "Immunology"
},
"field": {
"id": "https://openalex.org/fields/24",
"display_name": "Immunology and Microbiology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
{
"id": "https://openalex.org/T11688",
"display_name": "Bacterial Pathogenesis in Animal and Human Health",
"score": 0.9949,
"subfield": {
"id": "https://openalex.org/subfields/2404",
"display_name": "Microbiology"
},
"field": {
"id": "https://openalex.org/fields/24",
"display_name": "Immunology and Microbiology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
{
"id": "https://openalex.org/T13350",
"display_name": "Biology and Evolution of Myxozoan Parasites",
"score": 0.9916,
"subfield": {
"id": "https://openalex.org/subfields/1306",
"display_name": "Cancer Research"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-15T07:23:48.595551",
"versions": []
}
}
