Item talk:Q234189
From geokb
{
"USGS Publications Warehouse": { "@context": "https://schema.org", "@type": "Article", "additionalType": "Journal Article", "name": "Gene transcription in polar bears (Ursus maritimus) from disparate populations", "identifier": [ { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse IndexID", "value": "70156021", "url": "https://pubs.usgs.gov/publication/70156021" }, { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse Internal ID", "value": 70156021 }, { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s00300-015-1705-0", "url": "https://doi.org/10.1007/s00300-015-1705-0" } ], "journal": { "@type": "Periodical", "name": "Polar Biology", "volumeNumber": "38", "issueNumber": "9" }, "inLanguage": "en", "isPartOf": [ { "@type": "CreativeWorkSeries", "name": "Polar Biology" } ], "datePublished": "2015", "dateModified": "2015-08-13", "abstract": "Polar bears in the Beaufort (SB) and Chukchi (CS) Seas experience different environments due primarily to a longer history of sea ice loss in the Beaufort Sea. Ecological differences have been identified as a possible reason for the generally poorer body condition and reproduction of Beaufort polar bears compared to those from the Chukchi, but the influence of exposure to other stressors remains unknown. We use molecular technology, quantitative PCR, to identify gene transcription differences among polar bears from the Beaufort and Chukchi Seas as well as captive healthy polar bears. We identified significant transcriptional differences among a priori groups (i.e., captive bears, SB 2012, SB 2013, CS 2013) for ten of the 14 genes of interest (i.e., CaM, HSP70, CCR3, TGF\u03b2, COX2, THR\u03b1, T-bet, Gata3, CD69, and IL17); transcription levels of DR\u03b2, IL1\u03b2, AHR, and Mx1 did not differ among groups. Multivariate analysis also demonstrated separation among the groups of polar bears. Specifically, we detected transcript profiles consistent with immune function impairment in polar bears from the Beaufort Sea, when compared with Chukchi and captive polar bears. Although there is no strong indication of differential exposure to contaminants or pathogens between CS and SB bears, there are clearly differences in important transcriptional responses between populations. Further investigation is warranted to refine interpretation of potential effects of described stress-related conditions for the SB population.", "description": "15 p.", "publisher": { "@type": "Organization", "name": "Springer" }, "author": [ { "@type": "Person", "name": "Bowen, Lizabeth lbowen@usgs.gov", "givenName": "Lizabeth", "familyName": "Bowen", "email": "lbowen@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0001-9115-4336", "url": "https://orcid.org/0000-0001-9115-4336" }, "affiliation": [ { "@type": "Organization", "name": "Western Ecological Research Center", "url": "https://www.usgs.gov/centers/werc" } ] }, { "@type": "Person", "name": "Miles, A. Keith keith_miles@usgs.gov", "givenName": "A. Keith", "familyName": "Miles", "email": "keith_miles@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-3108-808X", "url": "https://orcid.org/0000-0002-3108-808X" }, "affiliation": [ { "@type": "Organization", "name": "Western Ecological Research Center", "url": "https://www.usgs.gov/centers/werc" } ] }, { "@type": "Person", "name": "Waters, Shannon C. swaters@usgs.gov", "givenName": "Shannon C.", "familyName": "Waters", "email": "swaters@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-9707-4684", "url": "https://orcid.org/0000-0002-9707-4684" }, "affiliation": [ { "@type": "Organization", "name": "Western Ecological Research Center", "url": "https://www.usgs.gov/centers/werc" } ] }, { "@type": "Person", "name": "Meyerson, Randi", "givenName": "Randi", "familyName": "Meyerson", "affiliation": [ { "@type": "Organization", "name": "Toledo Zoo, Toledo, OH" } ] }, { "@type": "Person", "name": "Rode, Karyn D. krode@usgs.gov", "givenName": "Karyn D.", "familyName": "Rode", "email": "krode@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-3328-8202", "url": "https://orcid.org/0000-0002-3328-8202" }, "affiliation": [ { "@type": "Organization", "name": "Alaska Science Center", "url": "https://www.usgs.gov/centers/alaska-science-center" }, { "@type": "Organization", "name": "Alaska Science Center Biology MFEB", "url": "https://www.usgs.gov/centers/alaska-science-center" } ] }, { "@type": "Person", "name": "Atwood, Todd C. tatwood@usgs.gov", "givenName": "Todd C.", "familyName": "Atwood", "email": "tatwood@usgs.gov", "identifier": { "@type": "PropertyValue", "propertyID": "ORCID", "value": "0000-0002-1971-3110", "url": "https://orcid.org/0000-0002-1971-3110" }, "affiliation": [ { "@type": "Organization", "name": "Alaska Science Center", "url": "https://www.usgs.gov/centers/alaska-science-center" }, { "@type": "Organization", "name": "Alaska Science Center Biology MFEB", "url": "https://www.usgs.gov/centers/alaska-science-center" } ] } ], "funder": [ { "@type": "Organization", "name": "Western Ecological Research Center", "url": "https://www.usgs.gov/centers/werc" } ] }, "OpenAlex": { "abstract_inverted_index": null, "apc_list": { "value": 2290, "currency": "EUR", "value_usd": 2890, "provenance": "doaj" }, "apc_paid": null, "authorships": [ { "author_position": "first", "author": { "id": "https://openalex.org/A5055897507", "display_name": "Lizabeth Bowen", "orcid": "https://orcid.org/0000-0001-9115-4336" }, "institutions": [ { "id": "https://openalex.org/I1286329397", "display_name": "United States Geological Survey", "ror": "https://ror.org/035a68863", "country_code": "US", "type": "government", "lineage": [ "https://openalex.org/I1286329397", "https://openalex.org/I1335927249" ] } ], "countries": [ "US" ], "is_corresponding": false, "raw_author_name": "Lizabeth Bowen", "raw_affiliation_strings": [ "Western Ecological Research Center, U.S. Geological Survey, Sacramento, USA" ], "affiliations": [ { "raw_affiliation_string": "Western Ecological Research Center, U.S. Geological Survey, Sacramento, USA", "institution_ids": [ "https://openalex.org/I1286329397" ] } ] }, { "author_position": "middle", "author": { "id": "https://openalex.org/A5021378161", "display_name": "A. 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