Item talk:Q227493

{

 "@context": "http://schema.org/",
 "@type": "WebPage",
 "additionalType": "Activity",
 "url": "https://www.usgs.gov/programs/environmental-health-program/science/immunomodulation-science-team",
 "headline": "Immunomodulation Science Team",
 "datePublished": "September 11, 2021",
 "author": [
   {
     "@type": "Person",
     "name": "Natalie Karouna-Renier, Ph.D.",
     "url": "https://www.usgs.gov/staff-profiles/natalie-karouna-renier",
     "identifier": {
       "@type": "PropertyValue",
       "propertyID": "orcid",
       "value": "0000-0001-7127-033X"
     }
   }
 ],
 "description": [
   {
     "@type": "TextObject",
     "text": "Exposure of wildlife, fish, and humans to environmental contaminants is known to cause changes in immune function, which can affect fitness, reproduction and disease resistance. This process, known as immunomodulation, is a major research topic by public health, veterinary, and other medical professionals outside the U.S. Geological Survey (USGS)."
   },
   {
     "@type": "TextObject",
     "text": "The science team research aims to identify immune responses, microbiome diversity and stability, and disease susceptibility in fish and wildlife exposed to contaminants and pathogens in the environment. They are also addressing key questions related to the role of contaminants in modulating susceptibility to pathogens, vulnerability to disease, and infectious disease outbreaks in wildlife. Eventually, the results of these studies will identify and prioritize the most important risk factors to fish and wildlife health and could be used to understand relevance for public health. the team is also actively engaged in the development of novel methods (genomic, immune, enzyme and hormone biomarkers to understand effects of contaminant classes commonly detected in the environment."
   },
   {
     "@type": "TextObject",
     "text": "The Team provides data and information that can inform risk analysis and assessments used by stakeholders to determine the role of contaminant and pathogen exposures on health and disease susceptibility."
   },
   {
     "@type": "TextObject",
     "text": "The Immunomodulation Integrated Science Team focuses on contaminant and pathogen exposures in the environment that might influence the immune systems of wildlife and the connection to their shared environment with humans. In collaboration with public-health officials, the Team also addresses potential human-health risks stemming from similar exposures.  If actual risks are identified, this Team will inform how to economically and effectively minimize risk by providing scientific data and understandings about the environmental transport, fate, and exposure pathways of contaminants and pathogens. Emphasis will be placed on addressing these issues on public and Department of the Interior managed landscapes."
   },
   {
     "@type": "TextObject",
     "text": "However, it is outside the mission of those professionals to answer questions about the possible link between exposure to toxicants in the environment and immunomodulation in fish and wildlife. With numerous chemicals being released into the environment every day, improved understandings of the interactions between chemical contaminants, pathogens, and infectious diseases is increasing in importance. In collaboration with multiple Federal, State, and local government agencies, universities and international governments, scientists in the Immunomodulation Science Team of the USGS' Environmental Health Program design and conduct field-based assessments and controlled exposures of birds, fish, and other wildlife to gain insights into immune responses that may affect critical terrestrial and aquatic populations."
   }
 ],
 "funder": {
   "@type": "Organization",
   "name": "Environmental Health Program",
   "url": "https://www.usgs.gov/programs/environmental-health-program"
 },
 "about": [
   {
     "@type": "Thing",
     "name": "Science Technology"
   },
   {
     "@type": "Thing",
     "name": "Applied Microbiology"
   },
   {
     "@type": "Thing",
     "name": "Biology"
   },
   {
     "@type": "Thing",
     "name": "Climate"
   },
   {
     "@type": "Thing",
     "name": "Health Effects"
   },
   {
     "@type": "Thing",
     "name": "Water"
   },
   {
     "@type": "Thing",
     "name": "Organic Chemistry Research"
   },
   {
     "@type": "Thing",
     "name": "Bioassays"
   },
   {
     "@type": "Thing",
     "name": "Science Teams"
   },
   {
     "@type": "Thing",
     "name": "Health Risks"
   },
   {
     "@type": "Thing",
     "name": "Geology"
   },
   {
     "@type": "Thing",
     "name": "Energy"
   },
   {
     "@type": "Thing",
     "name": "Exposure Pathways"
   },
   {
     "@type": "Thing",
     "name": "Sublethal Effects"
   },
   {
     "@type": "Thing",
     "name": "Environmental Toxicology"
   },
   {
     "@type": "Thing",
     "name": "Ecosystems"
   },
   {
     "@type": "Thing",
     "name": "Endocrine Disruption"
   },
   {
     "@type": "Thing",
     "name": "Immunomodulation"
   },
   {
     "@type": "Thing",
     "name": "Information Systems"
   },
   {
     "@type": "Thing",
     "name": "Immunomodulation Science Team"
   },
   {
     "@type": "Thing",
     "name": "Methods and Analysis"
   },
   {
     "@type": "Thing",
     "name": "Contaminant Transport and Effects"
   },
   {
     "@type": "Thing",
     "name": "Environmental Health"
   }
 ]

}