Item talk:Q168393

{

 "id": "https://openalex.org/T14415",
 "display_name": "Nephropathic Cystinosis Research",
 "description": "This cluster of papers focuses on nephropathic cystinosis, a rare genetic lysosomal storage disorder. The research covers various aspects including the pathogenesis, treatment with cysteamine therapy, complications in multiple organs (especially renal and ocular), molecular genetics involving CTNS gene mutations, and the impact on cellular processes such as autophagy and mitochondrial function.",
 "keywords": [
   "Cystinosis",
   "Cysteamine Therapy",
   "Lysosomal Dysfunction",
   "Pentose Phosphate Pathway",
   "CTNS Gene Mutations",
   "Renal Complications",
   "Ocular Manifestations",
   "Autophagy Impairment",
   "Transaldolase Deficiency",
   "Mitochondrial Dysfunction"
 ],
 "ids": {
   "openalex": "https://openalex.org/T14415",
   "wikipedia": "https://en.wikipedia.org/wiki/Cystinosis"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/2734",
   "display_name": "Pathology and Forensic Medicine"
 },
 "field": {
   "id": "https://openalex.org/fields/27",
   "display_name": "Medicine"
 },
 "domain": {
   "id": "https://openalex.org/domains/4",
   "display_name": "Health Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T11154",
     "display_name": "Biological, Epidemiological, and Clinical Aspects of Echinococcosis"
   },
   {
     "id": "https://openalex.org/T11134",
     "display_name": "Breast Pathology and Imaging Techniques"
   },
   {
     "id": "https://openalex.org/T13363",
     "display_name": "Clinical and Molecular Characteristics of Glomus Tumors"
   },
   {
     "id": "https://openalex.org/T10137",
     "display_name": "Diagnosis and Pathogenesis of Multiple Sclerosis"
   },
   {
     "id": "https://openalex.org/T13383",
     "display_name": "Granular Cell Tumor: Clinical and Pathological Characteristics"
   },
   {
     "id": "https://openalex.org/T11318",
     "display_name": "Health Effects of Soy Isoflavones and Phytoestrogens"
   },
   {
     "id": "https://openalex.org/T11411",
     "display_name": "Health Effects of Tea Polyphenols"
   },
   {
     "id": "https://openalex.org/T10185",
     "display_name": "Lymphoid Neoplasms"
   },
   {
     "id": "https://openalex.org/T12429",
     "display_name": "Mechanisms and Renoprotective Strategies for Cisplatin Nephrotoxicity"
   },
   {
     "id": "https://openalex.org/T14199",
     "display_name": "Medical Serial Killers and Forensic Toxicology"
   },
   {
     "id": "https://openalex.org/T11369",
     "display_name": "Molecular Characterization of Colorectal Cancer"
   },
   {
     "id": "https://openalex.org/T11207",
     "display_name": "Pathogenesis and Treatment of Alcoholic Liver Disease"
   },
   {
     "id": "https://openalex.org/T11730",
     "display_name": "Pathogenesis and Treatment of Pemphigoid Diseases"
   },
   {
     "id": "https://openalex.org/T11330",
     "display_name": "Pathogenesis and Treatment of Systemic Sclerosis"
   },
   {
     "id": "https://openalex.org/T13834",
     "display_name": "Pathogenesis and Treatment of Whipple's Disease"
   },
   {
     "id": "https://openalex.org/T12193",
     "display_name": "Pathology and Management of Trigeminal Neuralgia"
   },
   {
     "id": "https://openalex.org/T11538",
     "display_name": "Pathophysiology and Management of Graves' Ophthalmopathy"
   },
   {
     "id": "https://openalex.org/T10925",
     "display_name": "Pathophysiology and Treatment of Spinal Cord Injury"
   },
   {
     "id": "https://openalex.org/T10238",
     "display_name": "Pathophysiology of Lumbar Disc Degeneration and Treatment"
   },
   {
     "id": "https://openalex.org/T11057",
     "display_name": "Pathophysiology of Myocardial Reperfusion Injury"
   },
   {
     "id": "https://openalex.org/T13779",
     "display_name": "Role of Pim Oncogenes in Tumorigenesis"
   },
   {
     "id": "https://openalex.org/T10277",
     "display_name": "Vitamin D and Health Outcomes"
   }
 ],
 "works_count": 22942,
 "cited_by_count": 196747,
 "updated_date": "2024-08-26T05:20:32.995663",
 "created_date": "2024-01-23"

}