Item talk:Q168237

{

 "OpenAlex": {
   "cited_by_count": 62766,
   "created_date": "2024-01-23",
   "description": "This cluster of papers focuses on the development and evaluation of protein phosphatase inhibitors, such as Cantharidin and Norcantharidin, as potential anticancer agents. The research involves studying their mechanisms of action, including induction of apoptosis, cell cycle arrest, and inhibition of cancer cell growth. Additionally, the cluster explores the molecular identification of pederin biosynthesis and the pharmacological evaluation of these inhibitors.",
   "display_name": "Development of Protein Phosphatase Inhibitors as Anticancer Agents",
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "id": "https://openalex.org/T13943",
   "ids": {
     "openalex": "https://openalex.org/T13943",
     "wikipedia": "https://en.wikipedia.org/wiki/Protein_phosphatase_inhibitor"
   },
   "keywords": [
     "Protein Phosphatase Inhibitors",
     "Cantharidin",
     "Norcantharidin",
     "Anticancer Activity",
     "Apoptosis",
     "Cell Cycle Arrest",
     "Sponge-Derived Cytotoxin",
     "Pederin Biosynthesis",
     "Molecular Identification",
     "Pharmacological Evaluation"
   ],
   "siblings": [
     {
       "id": "https://openalex.org/T11547",
       "display_name": "Biological Activities of Sesquiterpene Lactones in Cancer"
     },
     {
       "id": "https://openalex.org/T13350",
       "display_name": "Biology and Evolution of Myxozoan Parasites"
     },
     {
       "id": "https://openalex.org/T13971",
       "display_name": "Chemistry and Biology of Antitumor Antibiotics"
     },
     {
       "id": "https://openalex.org/T11287",
       "display_name": "Genomic Landscape of Cancer and Mutational Signatures"
     },
     {
       "id": "https://openalex.org/T10433",
       "display_name": "Genotoxicity and Carcinogenesis Mechanisms"
     },
     {
       "id": "https://openalex.org/T12465",
       "display_name": "Lipid Metabolism in Cancer Pathogenesis"
     },
     {
       "id": "https://openalex.org/T10631",
       "display_name": "Metabolic Reprogramming in Cancer Biology"
     },
     {
       "id": "https://openalex.org/T10062",
       "display_name": "MicroRNA Regulation in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10183",
       "display_name": "Molecular Research on Breast Cancer"
     },
     {
       "id": "https://openalex.org/T11591",
       "display_name": "NF-?B Signaling in Inflammation and Cancer"
     },
     {
       "id": "https://openalex.org/T10515",
       "display_name": "Role of Long Noncoding RNAs in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10620",
       "display_name": "Role of Matrix Metalloproteinases in Cancer and Physiology"
     }
   ],
   "subfield": {
     "id": "https://openalex.org/subfields/1306",
     "display_name": "Cancer Research"
   },
   "updated_date": "2024-08-19T06:14:58.286083",
   "works_count": 6820,
   "oa_id": "T13943"
 }

}