Item talk:Q168197
From geokb
{
"OpenAlex": {
"cited_by_count": 1659660,
"created_date": "2024-01-23",
"description": "This cluster of papers focuses on the molecular mechanisms of Ras signaling pathways, including the role of protein kinases, GTPases, and phospholipase C in cell regulation and cancer therapy. It explores the involvement of calcium signaling, cell migration, and transcriptional regulation in oncogenic mutations.",
"display_name": "Molecular Mechanisms of Ras Signaling Pathways",
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"id": "https://openalex.org/T10169",
"ids": {
"openalex": "https://openalex.org/T10169",
"wikipedia": "https://en.wikipedia.org/wiki/Ras_signaling"
},
"keywords": [
"Ras Signaling",
"Protein Kinases",
"GTPases",
"Cell Regulation",
"Cancer Therapy",
"Calcium Signaling",
"Phospholipase C",
"Cell Migration",
"Oncogenic Mutations",
"Transcriptional Regulation"
],
"siblings": [
{
"id": "https://openalex.org/T13526",
"display_name": "14-3-3 Proteins: Structure, Function, and Regulation"
},
{
"id": "https://openalex.org/T10836",
"display_name": "Advances in Metabolomics Research"
},
{
"id": "https://openalex.org/T10887",
"display_name": "Analysis of Gene Interaction Networks"
},
{
"id": "https://openalex.org/T12763",
"display_name": "ATP Synthase Function and Regulation"
},
{
"id": "https://openalex.org/T10593",
"display_name": "Bacterial Biofilms and Quorum Sensing Mechanisms"
},
{
"id": "https://openalex.org/T12685",
"display_name": "Bioactive Limonoids in Medicinal Plants"
},
{
"id": "https://openalex.org/T11561",
"display_name": "Bioactive Peptides in Food and Health"
},
{
"id": "https://openalex.org/T12215",
"display_name": "Bioactivity of Steroidal Saponins in Medicinal Plants"
},
{
"id": "https://openalex.org/T13188",
"display_name": "Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids"
},
{
"id": "https://openalex.org/T13725",
"display_name": "Biochemistry, Pharmacology, and Medical Use of Bromelain"
},
{
"id": "https://openalex.org/T11765",
"display_name": "Biogenesis and Functions of Circular RNAs"
},
{
"id": "https://openalex.org/T12530",
"display_name": "Biological Activities of Diterpenoids from Medicinal Plants"
},
{
"id": "https://openalex.org/T13454",
"display_name": "Biological Activities of Phenothiazines and Related Compounds"
},
{
"id": "https://openalex.org/T12257",
"display_name": "Biological Activities of Prenylated Flavonoids"
},
{
"id": "https://openalex.org/T11385",
"display_name": "Biological Activities of Triterpenoids and Saponins"
},
{
"id": "https://openalex.org/T13221",
"display_name": "Biological Activity of Diterpenoids and Biflavonoids"
},
{
"id": "https://openalex.org/T11515",
"display_name": "Biological Agents for Bioterrorism"
},
{
"id": "https://openalex.org/T12688",
"display_name": "Biological Methane Utilization and Metabolism"
},
{
"id": "https://openalex.org/T12561",
"display_name": "Bioluminescence Imaging and Reporter Systems"
},
{
"id": "https://openalex.org/T11710",
"display_name": "Biomedical Ontologies and Text Mining"
},
{
"id": "https://openalex.org/T11882",
"display_name": "Biosynthesis and Engineering of Terpenoids"
},
{
"id": "https://openalex.org/T12360",
"display_name": "Biosynthesis and Pharmacological Activities of Lignans"
},
{
"id": "https://openalex.org/T12620",
"display_name": "Calcineurin-NFAT Signaling in Transcriptional Regulation"
},
{
"id": "https://openalex.org/T13937",
"display_name": "Challenges and Innovations in Bioinformatics Education"
},
{
"id": "https://openalex.org/T12683",
"display_name": "Chitin Metabolism in Insects and Mammals"
},
{
"id": "https://openalex.org/T12820",
"display_name": "Chromatin Remodeling in Cancer and Development"
},
{
"id": "https://openalex.org/T10878",
"display_name": "Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins"
},
{
"id": "https://openalex.org/T11289",
"display_name": "Comprehensive Integration of Single-Cell Transcriptomic Data"
},
{
"id": "https://openalex.org/T13326",
"display_name": "Cyclotide Bioengineering and Protein Anchoring Mechanisms"
},
{
"id": "https://openalex.org/T10066",
"display_name": "Diversity and Function of Gut Microbiome"
},
{
"id": "https://openalex.org/T12668",
"display_name": "Diversity and Systematics of Yeasts"
},
{
"id": "https://openalex.org/T12388",
"display_name": "DNA Barcoding for Food Authentication and Fraud Detection"
},
{
"id": "https://openalex.org/T10207",
"display_name": "DNA Nanotechnology and Bioanalytical Applications"
},
{
"id": "https://openalex.org/T11845",
"display_name": "DNA Topoisomerases: Structure, Function, and Inhibition"
},
{
"id": "https://openalex.org/T12029",
"display_name": "DNA-based Computing and Data Storage"
},
{
"id": "https://openalex.org/T10240",
"display_name": "Elicitor Signal Transduction for Metabolite Production"
},
{
"id": "https://openalex.org/T10404",
"display_name": "Enzyme Immobilization Techniques"
},
{
"id": "https://openalex.org/T10269",
"display_name": "Epigenetic Modifications and Their Functional Implications"
},
{
"id": "https://openalex.org/T10773",
"display_name": "Exosome Biology and Function in Intercellular Communication"
},
{
"id": "https://openalex.org/T12287",
"display_name": "Fibroblast Growth Factor Signaling Pathway"
},
{
"id": "https://openalex.org/T12610",
"display_name": "Functions and Regulation of RNA Editing by ADARs"
},
{
"id": "https://openalex.org/T10432",
"display_name": "G-Quadruplex DNA Structures and Functions"
},
{
"id": "https://openalex.org/T10497",
"display_name": "Genomic Expression and Function in Yeast Organism"
},
{
"id": "https://openalex.org/T12946",
"display_name": "Genomic Signal Processing and Analysis Techniques"
},
{
"id": "https://openalex.org/T11879",
"display_name": "Global Diversity of Microbial Eukaryotes and Their Evolution"
},
{
"id": "https://openalex.org/T10602",
"display_name": "Glycosylation in Health and Disease"
},
{
"id": "https://openalex.org/T12009",
"display_name": "Hedgehog Signaling in Development and Cancer"
},
{
"id": "https://openalex.org/T11848",
"display_name": "Heme Oxygenase and Carbon Monoxide Research"
},
{
"id": "https://openalex.org/T10505",
"display_name": "Induction and Differentiation of Pluripotent Stem Cells"
},
{
"id": "https://openalex.org/T10407",
"display_name": "Lipid Rafts and Membrane Dynamics"
},
{
"id": "https://openalex.org/T11786",
"display_name": "Magnetosome Formation in Prokaryotes"
},
{
"id": "https://openalex.org/T11533",
"display_name": "Mammalian MAP Kinase Signaling Pathways"
},
{
"id": "https://openalex.org/T10725",
"display_name": "Mechanisms and Applications of RNA Interference"
},
{
"id": "https://openalex.org/T10932",
"display_name": "Metabolic Engineering and Synthetic Biology"
},
{
"id": "https://openalex.org/T13012",
"display_name": "Metabolism and Functions of Coenzyme Q"
},
{
"id": "https://openalex.org/T10885",
"display_name": "Microarray Data Analysis and Gene Expression Profiling"
},
{
"id": "https://openalex.org/T14285",
"display_name": "Microbial Production of Polyglutamic Acid"
},
{
"id": "https://openalex.org/T13736",
"display_name": "Microbial Transformation of Steroids"
},
{
"id": "https://openalex.org/T10301",
"display_name": "Mitochondrial Dynamics and Reactive Oxygen Species Regulation"
},
{
"id": "https://openalex.org/T11956",
"display_name": "Molecular Biology of Steroidogenesis and Disorders"
},
{
"id": "https://openalex.org/T10934",
"display_name": "Molecular Chaperones in Protein Folding and Disease"
},
{
"id": "https://openalex.org/T11889",
"display_name": "Molecular Mechanisms and Medical Applications of Ginseng"
},
{
"id": "https://openalex.org/T11305",
"display_name": "Molecular Mechanisms of Amyloidosis"
},
{
"id": "https://openalex.org/T10422",
"display_name": "Molecular Mechanisms of Angiogenesis and Vascular Function"
},
{
"id": "https://openalex.org/T10294",
"display_name": "Molecular Mechanisms of Apoptosis and Cell Death"
},
{
"id": "https://openalex.org/T10724",
"display_name": "Molecular Mechanisms of Aquaporins in Physiology and Disease"
},
{
"id": "https://openalex.org/T11677",
"display_name": "Molecular Mechanisms of Cardiac Development and Regeneration"
},
{
"id": "https://openalex.org/T10123",
"display_name": "Molecular Mechanisms of DNA Damage Response"
},
{
"id": "https://openalex.org/T11237",
"display_name": "Molecular Mechanisms of Flavonoid Biosynthesis in Plants"
},
{
"id": "https://openalex.org/T12441",
"display_name": "Molecular Mechanisms of Heme Biosynthesis and Related Disorders"
},
{
"id": "https://openalex.org/T11078",
"display_name": "Molecular Mechanisms of Inflammasome Activation and Regulation"
},
{
"id": "https://openalex.org/T11075",
"display_name": "Molecular Mechanisms of Insect Resistance to Xenobiotics"
},
{
"id": "https://openalex.org/T10493",
"display_name": "Molecular Mechanisms of Ion Channels Regulation"
},
{
"id": "https://openalex.org/T12140",
"display_name": "Molecular Mechanisms of Kidney Development and Disease"
},
{
"id": "https://openalex.org/T13437",
"display_name": "Molecular Mechanisms of Metastasis Suppressor Genes"
},
{
"id": "https://openalex.org/T10441",
"display_name": "Molecular Mechanisms of Muscle Regeneration and Atrophy"
},
{
"id": "https://openalex.org/T11219",
"display_name": "Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling"
},
{
"id": "https://openalex.org/T10303",
"display_name": "Molecular Mechanisms of Photosynthesis and Photoprotection"
},
{
"id": "https://openalex.org/T12789",
"display_name": "Molecular Mechanisms of Planarian Regeneration"
},
{
"id": "https://openalex.org/T11927",
"display_name": "Molecular Mechanisms of Pollen Development and Function"
},
{
"id": "https://openalex.org/T10691",
"display_name": "Molecular Mechanisms of Retinal Degeneration and Regeneration"
},
{
"id": "https://openalex.org/T11919",
"display_name": "Molecular Mechanisms of Tooth Development and Morphogenesis"
},
{
"id": "https://openalex.org/T12434",
"display_name": "Molecular Regulation and Clinical Applications of PDEs"
},
{
"id": "https://openalex.org/T12566",
"display_name": "Molecular Regulation of Sulfur Metabolism in Plants"
},
{
"id": "https://openalex.org/T14049",
"display_name": "Molecular Systematics of Gesneriaceae and Allies"
},
{
"id": "https://openalex.org/T10952",
"display_name": "mTOR Signaling in Growth and Disease"
},
{
"id": "https://openalex.org/T10268",
"display_name": "Notch Signaling Pathway in Development and Disease"
},
{
"id": "https://openalex.org/T12827",
"display_name": "Nucleotide Metabolism and Enzyme Regulation"
},
{
"id": "https://openalex.org/T14135",
"display_name": "Oxidation States in Biochemistry and Medicine"
},
{
"id": "https://openalex.org/T10911",
"display_name": "Peptide Synthesis and Drug Discovery"
},
{
"id": "https://openalex.org/T11072",
"display_name": "Peroxisome Proliferator-Activated Receptors"
},
{
"id": "https://openalex.org/T11924",
"display_name": "Polyamines and Biogenic Amines in Biology and Health"
},
{
"id": "https://openalex.org/T12576",
"display_name": "Prediction of Peptide-MHC Binding Affinity"
},
{
"id": "https://openalex.org/T12254",
"display_name": "Prediction of Protein Subcellular Localization"
},
{
"id": "https://openalex.org/T11335",
"display_name": "Prion Diseases: Causes and Molecular Basis"
},
{
"id": "https://openalex.org/T11124",
"display_name": "Protein Aggregation and Biopharmaceutical Stability"
},
{
"id": "https://openalex.org/T13157",
"display_name": "Protein Arginine Methylation in Mammals"
},
{
"id": "https://openalex.org/T11908",
"display_name": "Protein Binding Specificity in Human Serum Albumin"
},
{
"id": "https://openalex.org/T12867",
"display_name": "Protein Microarray Technology and Applications"
},
{
"id": "https://openalex.org/T10044",
"display_name": "Protein Structure Prediction and Analysis"
},
{
"id": "https://openalex.org/T12104",
"display_name": "Protein Tyrosine Phosphatases in Human Health and Disease"
},
{
"id": "https://openalex.org/T13187",
"display_name": "Protein-DNA Interaction Dynamics in Living Cells"
},
{
"id": "https://openalex.org/T12756",
"display_name": "Pyrrolizidine Alkaloids: Toxicity, Metabolism, and Health Implications"
},
{
"id": "https://openalex.org/T11970",
"display_name": "Real-Time Polymerase Chain Reaction"
},
{
"id": "https://openalex.org/T11663",
"display_name": "Recombinant Protein Production in Mammalian and Insect Cells"
},
{
"id": "https://openalex.org/T11884",
"display_name": "Redox Signaling and Oxidative Stress"
},
{
"id": "https://openalex.org/T12835",
"display_name": "Regulation and Functions of FoxO Transcription Factors"
},
{
"id": "https://openalex.org/T10222",
"display_name": "Regulation of Chromatin Structure and Function"
},
{
"id": "https://openalex.org/T10604",
"display_name": "Regulation of RNA Processing and Function"
},
{
"id": "https://openalex.org/T13651",
"display_name": "Research on Rhodiola rosea and Salidroside"
},
{
"id": "https://openalex.org/T14065",
"display_name": "Research on Synthetic Phosphoethanolamine and its Effects"
},
{
"id": "https://openalex.org/T10521",
"display_name": "Ribosome Structure and Translation Mechanisms"
},
{
"id": "https://openalex.org/T11482",
"display_name": "RNA Methylation and Modification in Gene Expression"
},
{
"id": "https://openalex.org/T10015",
"display_name": "RNA Sequencing Data Analysis"
},
{
"id": "https://openalex.org/T11339",
"display_name": "Role of AMP-Activated Protein Kinase in Cellular Metabolism"
},
{
"id": "https://openalex.org/T12412",
"display_name": "Role of Carbonic Anhydrases in Medicine and Biotechnology"
},
{
"id": "https://openalex.org/T13223",
"display_name": "Role of CCN Proteins in Signaling Pathways"
},
{
"id": "https://openalex.org/T12187",
"display_name": "Role of Glutathione in Oxidative Stress Response"
},
{
"id": "https://openalex.org/T11736",
"display_name": "Role of Histone Deacetylases in Cellular Regulation"
},
{
"id": "https://openalex.org/T11332",
"display_name": "Role of Nrf2 Signaling in Oxidative Stress Response"
},
{
"id": "https://openalex.org/T11559",
"display_name": "Role of Retinoic Acid in Biological Processes"
},
{
"id": "https://openalex.org/T13047",
"display_name": "Role of Sigma Receptors in Cellular Signaling"
},
{
"id": "https://openalex.org/T13426",
"display_name": "Role of Transcription Factors in Cell Regulation"
},
{
"id": "https://openalex.org/T12030",
"display_name": "S100 Proteins: Structure, Function, and Pathology"
},
{
"id": "https://openalex.org/T11308",
"display_name": "Sphingolipid Signalling and Metabolism in Health and Disease"
},
{
"id": "https://openalex.org/T10621",
"display_name": "Stochasticity in Gene Regulatory Networks"
},
{
"id": "https://openalex.org/T11178",
"display_name": "Structure and Function of G Protein-Coupled Receptors"
},
{
"id": "https://openalex.org/T11480",
"display_name": "Structure and Function of Gap Junctions and Connexins"
},
{
"id": "https://openalex.org/T11818",
"display_name": "Structure and Function of Nicotinic Receptors"
},
{
"id": "https://openalex.org/T11841",
"display_name": "Structure and Function of the Nuclear Pore Complex"
},
{
"id": "https://openalex.org/T12534",
"display_name": "Targeted Protein Degradation in Biomedical Research"
},
{
"id": "https://openalex.org/T11501",
"display_name": "Transforming Growth Factor Beta Signaling Pathway"
},
{
"id": "https://openalex.org/T11041",
"display_name": "Ubiquitin-Proteasome Proteolytic Pathway"
},
{
"id": "https://openalex.org/T10929",
"display_name": "Wnt Signaling in Development and Disease"
}
],
"subfield": {
"id": "https://openalex.org/subfields/1312",
"display_name": "Molecular Biology"
},
"updated_date": "2024-08-19T05:20:29.770100",
"works_count": 32716,
"oa_id": "T10169"
}
}
