Item talk:Q167814

{

 "OpenAlex": {
   "cited_by_count": 2521428,
   "created_date": "2024-01-23",
   "description": "This cluster of papers explores the metabolic reprogramming in cancer cells, focusing on the role of hypoxia-inducible factor 1 (HIF-1), the Warburg effect, tumor hypoxia, glutamine metabolism, and the impact of the tumor microenvironment on cancer cell metabolism. It also delves into oxygen sensing, mitochondrial metabolism, glycolysis inhibition, and the role of hexokinase II in cancer progression.",
   "display_name": "Metabolic Reprogramming in Cancer Biology",
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "id": "https://openalex.org/T10631",
   "ids": {
     "openalex": "https://openalex.org/T10631",
     "wikipedia": "https://en.wikipedia.org/wiki/Cancer_metabolism"
   },
   "keywords": [
     "HIF-1",
     "Warburg Effect",
     "Tumor Hypoxia",
     "Cancer Cell Metabolism",
     "Glutamine Metabolism",
     "Oxygen Sensing",
     "Mitochondrial Metabolism",
     "Glycolysis Inhibition",
     "Tumor Microenvironment",
     "Hexokinase II"
   ],
   "siblings": [
     {
       "id": "https://openalex.org/T11547",
       "display_name": "Biological Activities of Sesquiterpene Lactones in Cancer"
     },
     {
       "id": "https://openalex.org/T13350",
       "display_name": "Biology and Evolution of Myxozoan Parasites"
     },
     {
       "id": "https://openalex.org/T13971",
       "display_name": "Chemistry and Biology of Antitumor Antibiotics"
     },
     {
       "id": "https://openalex.org/T13943",
       "display_name": "Development of Protein Phosphatase Inhibitors as Anticancer Agents"
     },
     {
       "id": "https://openalex.org/T11287",
       "display_name": "Genomic Landscape of Cancer and Mutational Signatures"
     },
     {
       "id": "https://openalex.org/T10433",
       "display_name": "Genotoxicity and Carcinogenesis Mechanisms"
     },
     {
       "id": "https://openalex.org/T12465",
       "display_name": "Lipid Metabolism in Cancer Pathogenesis"
     },
     {
       "id": "https://openalex.org/T10062",
       "display_name": "MicroRNA Regulation in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10183",
       "display_name": "Molecular Research on Breast Cancer"
     },
     {
       "id": "https://openalex.org/T11591",
       "display_name": "NF-?B Signaling in Inflammation and Cancer"
     },
     {
       "id": "https://openalex.org/T10515",
       "display_name": "Role of Long Noncoding RNAs in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10620",
       "display_name": "Role of Matrix Metalloproteinases in Cancer and Physiology"
     }
   ],
   "subfield": {
     "id": "https://openalex.org/subfields/1306",
     "display_name": "Cancer Research"
   },
   "updated_date": "2024-08-19T06:06:11.363849",
   "works_count": 115150,
   "oa_id": "T10631"
 }

}