Item talk:Q167690

{

 "id": "https://openalex.org/T10949",
 "display_name": "Molecular Mechanisms of Neurodegenerative Diseases",
 "description": "This cluster of papers explores the molecular mechanisms underlying neurodegenerative diseases such as Huntington's disease, myotonic dystrophy, and ataxias. It focuses on protein aggregation, polyglutamine toxicity, mitochondrial dysfunction, RNA-mediated disorders, chaperone function, gene expression dysregulation, and the role of trinucleotide repeats in neuronal degeneration.",
 "keywords": [
   "Huntington's Disease",
   "Protein Aggregation",
   "Polyglutamine",
   "Mitochondrial Dysfunction",
   "RNA-Mediated Disorders",
   "Ataxia",
   "Chaperones",
   "Gene Expression Dysregulation",
   "Trinucleotide Repeats",
   "Neuronal Degeneration"
 ],
 "ids": {
   "openalex": "https://openalex.org/T10949",
   "wikipedia": "https://en.wikipedia.org/wiki/Neurodegenerative_disease"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/2804",
   "display_name": "Cellular and Molecular Neuroscience"
 },
 "field": {
   "id": "https://openalex.org/fields/28",
   "display_name": "Neuroscience"
 },
 "domain": {
   "id": "https://openalex.org/domains/1",
   "display_name": "Life Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T11406",
     "display_name": "Brain Fluid Dynamics and Waste Clearance Mechanisms"
   },
   {
     "id": "https://openalex.org/T13446",
     "display_name": "Effects of D-Galactose on Aging and Neurodegeneration"
   },
   {
     "id": "https://openalex.org/T12331",
     "display_name": "Genetic Basis of Neuropathies and Related Disorders"
   },
   {
     "id": "https://openalex.org/T12061",
     "display_name": "Molecular Mechanisms of Axon Guidance"
   },
   {
     "id": "https://openalex.org/T10077",
     "display_name": "Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders"
   },
   {
     "id": "https://openalex.org/T11601",
     "display_name": "Neural Interface Technology"
   },
   {
     "id": "https://openalex.org/T10056",
     "display_name": "Neurobiological Mechanisms of Drug Addiction and Depression"
   },
   {
     "id": "https://openalex.org/T10423",
     "display_name": "Neuroscience and Genetics of Drosophila Melanogaster"
   },
   {
     "id": "https://openalex.org/T13991",
     "display_name": "Nurr1/CoREST Pathway in Neuroprotection and Inflammation"
   },
   {
     "id": "https://openalex.org/T12236",
     "display_name": "Optogenetics in Neuroscience and Biophysics Research"
   },
   {
     "id": "https://openalex.org/T10814",
     "display_name": "Role of Neuropeptides in Physiology and Disease"
   },
   {
     "id": "https://openalex.org/T10483",
     "display_name": "Roles of Neurotrophins in Nervous System Function"
   }
 ],
 "works_count": 66861,
 "cited_by_count": 1538709,
 "updated_date": "2024-08-26T05:20:08.819937",
 "created_date": "2024-01-23"

}