Item talk:Q167536

{

 "id": "https://openalex.org/T11725",
 "display_name": "Genetic Basis of Primary Immunodeficiency Disorders",
 "description": "This cluster of papers focuses on the genetic basis and clinical manifestations of primary immunodeficiency disorders, including immune dysregulation, Th17 cell deficiency, common variable immunodeficiency, and defects in the interferon-? pathway. It also discusses the use of hematopoietic stem cell transplantation and immunoglobulin replacement therapy in the management of these disorders.",
 "keywords": [
   "Primary Immunodeficiency",
   "Genetic Mutations",
   "Immune Dysregulation",
   "Human Inborn Errors",
   "Th17 Cell Deficiency",
   "Common Variable Immunodeficiency",
   "Hematopoietic Stem Cell Transplantation",
   "Interferon-? Pathway Defects",
   "B Cell Abnormalities",
   "Immunoglobulin Replacement Therapy"
 ],
 "ids": {
   "openalex": "https://openalex.org/T11725",
   "wikipedia": "https://en.wikipedia.org/wiki/Primary_immunodeficiency"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/2403",
   "display_name": "Immunology"
 },
 "field": {
   "id": "https://openalex.org/fields/24",
   "display_name": "Immunology and Microbiology"
 },
 "domain": {
   "id": "https://openalex.org/domains/1",
   "display_name": "Life Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T12159",
     "display_name": "Human T-cell Leukemia Virus Type 1 Infection"
   },
   {
     "id": "https://openalex.org/T10580",
     "display_name": "Immunobiology of Dendritic Cells"
   },
   {
     "id": "https://openalex.org/T12255",
     "display_name": "Immunogenicity of Biosimilar Therapeutics in Drug Development"
   },
   {
     "id": "https://openalex.org/T12955",
     "display_name": "Immunological Mechanisms in Atherosclerosis Development"
   },
   {
     "id": "https://openalex.org/T11510",
     "display_name": "Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface"
   },
   {
     "id": "https://openalex.org/T10506",
     "display_name": "Immunological Responses in Aquatic Organisms"
   },
   {
     "id": "https://openalex.org/T14072",
     "display_name": "Immunotoxicology in Toxicologic Pathology Research"
   },
   {
     "id": "https://openalex.org/T12477",
     "display_name": "Immunotoxin Therapy for Cancer Treatment"
   },
   {
     "id": "https://openalex.org/T10371",
     "display_name": "Innate Immune Recognition and Signaling Pathways"
   },
   {
     "id": "https://openalex.org/T11668",
     "display_name": "Innate Immunity to Viral Infection"
   },
   {
     "id": "https://openalex.org/T12528",
     "display_name": "Innate Lymphoid Cells in Immunity"
   },
   {
     "id": "https://openalex.org/T11403",
     "display_name": "Invertebrate Immunity and Host Defense Mechanisms"
   },
   {
     "id": "https://openalex.org/T11313",
     "display_name": "Macrophage Activation and Polarization"
   },
   {
     "id": "https://openalex.org/T12672",
     "display_name": "Mechanisms of Apoptotic Cell Clearance and Immune Regulation"
   },
   {
     "id": "https://openalex.org/T11020",
     "display_name": "Natural Killer Cells in Immunity"
   },
   {
     "id": "https://openalex.org/T10469",
     "display_name": "Reciprocal Development of TH17 and Treg Cells"
   },
   {
     "id": "https://openalex.org/T10031",
     "display_name": "Regulatory T Cell Development and Function"
   },
   {
     "id": "https://openalex.org/T10993",
     "display_name": "Role of Complement System in Immune Response"
   },
   {
     "id": "https://openalex.org/T12387",
     "display_name": "Role of Galectins in Immunity and Disease"
   },
   {
     "id": "https://openalex.org/T13254",
     "display_name": "Role of Macrophage Migration Inhibitory Factor"
   },
   {
     "id": "https://openalex.org/T11346",
     "display_name": "Role of Mast Cells in Immunoregulation and Disease"
   },
   {
     "id": "https://openalex.org/T11597",
     "display_name": "Role of Neutrophil Extracellular Traps in Immunity"
   },
   {
     "id": "https://openalex.org/T14245",
     "display_name": "Role of Pentraxins in Innate Immunity and Inflammation"
   },
   {
     "id": "https://openalex.org/T14165",
     "display_name": "Role of TREM-1 and Endocan in Inflammation"
   },
   {
     "id": "https://openalex.org/T13410",
     "display_name": "Trained Immunity in Health and Disease"
   }
 ],
 "works_count": 88396,
 "cited_by_count": 934628,
 "updated_date": "2024-08-26T05:24:26.011341",
 "created_date": "2024-01-23"

}