Item talk:Q167308

{

 "OpenAlex": {
   "cited_by_count": 750536,
   "created_date": "2024-01-23",
   "description": "This cluster of papers explores genetic and molecular aspects of various connective tissue disorders, including Marfan syndrome, Ehlers-Danlos syndrome, and Osteogenesis Imperfecta. It delves into mutations in genes encoding proteins like TGF-\u00df receptor, elastin, fibrillin-1, and collagen, as well as their implications in aortic aneurysms and skeletal abnormalities.",
   "display_name": "Genetic and Molecular Studies of Connective Tissue Disorders",
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "id": "https://openalex.org/T11310",
   "ids": {
     "openalex": "https://openalex.org/T11310",
     "wikipedia": "https://en.wikipedia.org/wiki/Connective_tissue_disease"
   },
   "keywords": [
     "Marfan Syndrome",
     "Ehlers-Danlos Syndrome",
     "Osteogenesis Imperfecta",
     "TGF-\u00df Receptor Mutations",
     "Elastin",
     "Fibrillin-1",
     "Smooth Muscle Alpha-Actin Mutations",
     "Collagen Disorders",
     "Aortic Aneurysm",
     "Genetic Skeletal Disorders"
   ],
   "siblings": [
     {
       "id": "https://openalex.org/T10120",
       "display_name": "Bacterial Physiology and Genetics"
     },
     {
       "id": "https://openalex.org/T11412",
       "display_name": "Ciliopathies: Genetic Disorders Involving Primary Cilia"
     },
     {
       "id": "https://openalex.org/T14333",
       "display_name": "Dermatoglyphics in Medical Research and Genetics"
     },
     {
       "id": "https://openalex.org/T11974",
       "display_name": "DNA Barcoding for Lepidoptera Taxonomy and Evolution"
     },
     {
       "id": "https://openalex.org/T11764",
       "display_name": "Evolutionary Dynamics of Genetic Adaptation and Mutation"
     },
     {
       "id": "https://openalex.org/T10613",
       "display_name": "Gene Therapy Techniques and Applications"
     },
     {
       "id": "https://openalex.org/T13199",
       "display_name": "Genetic Adaptation of Lactase Persistence in Humans"
     },
     {
       "id": "https://openalex.org/T11214",
       "display_name": "Genetic and Behavioral Studies on Dog Domestication"
     },
     {
       "id": "https://openalex.org/T12989",
       "display_name": "Genetic and Clinical Studies of Ocular Development"
     },
     {
       "id": "https://openalex.org/T11374",
       "display_name": "Genetic and Environmental Influences on Cleft Lip and Palate"
     },
     {
       "id": "https://openalex.org/T12232",
       "display_name": "Genetic and Pathogenic Study of Plague Bacteria"
     },
     {
       "id": "https://openalex.org/T11968",
       "display_name": "Genetic and Physiological Adaptations to High-Altitude Environments"
     },
     {
       "id": "https://openalex.org/T11468",
       "display_name": "Genetic Architecture of Quantitative Traits"
     },
     {
       "id": "https://openalex.org/T12919",
       "display_name": "Genetic Basis of Neutropenia Disorders"
     },
     {
       "id": "https://openalex.org/T12924",
       "display_name": "Genetic Disorders Causing Tissue Mineralization Abnormalities"
     },
     {
       "id": "https://openalex.org/T13354",
       "display_name": "Genetic Influence on Human Athletic Performance"
     },
     {
       "id": "https://openalex.org/T10769",
       "display_name": "Genetic Research on BRCA Mutations and Cancer Risk"
     },
     {
       "id": "https://openalex.org/T11679",
       "display_name": "Genetics and Development of Craniofacial Abnormalities"
     },
     {
       "id": "https://openalex.org/T12370",
       "display_name": "Genetics and Genomics of Cucurbitaceae Family"
     },
     {
       "id": "https://openalex.org/T11171",
       "display_name": "Genetics and Pathogenesis of Type 1 Diabetes"
     },
     {
       "id": "https://openalex.org/T10134",
       "display_name": "Genetics and Treatment of Inflammatory Bowel Disease"
     },
     {
       "id": "https://openalex.org/T10751",
       "display_name": "Genomic Analysis of Ancient DNA"
     },
     {
       "id": "https://openalex.org/T11928",
       "display_name": "Genomic Imprinting and Parental Gene Expression Control"
     },
     {
       "id": "https://openalex.org/T10702",
       "display_name": "Genomic Insights into Social Insects and Symbiosis"
     },
     {
       "id": "https://openalex.org/T12355",
       "display_name": "Genomic Rearrangement Disorders in Skin Diseases"
     },
     {
       "id": "https://openalex.org/T11213",
       "display_name": "Genomic Rearrangements and Copy Number Variations"
     },
     {
       "id": "https://openalex.org/T13664",
       "display_name": "Genomic Rearrangements in Evolutionary Biology"
     },
     {
       "id": "https://openalex.org/T10594",
       "display_name": "Genomic Selection in Plant and Animal Breeding"
     },
     {
       "id": "https://openalex.org/T10261",
       "display_name": "Genomic Studies and Association Analyses"
     },
     {
       "id": "https://openalex.org/T10756",
       "display_name": "Mechanisms of Estrogen Receptor Signaling"
     },
     {
       "id": "https://openalex.org/T11772",
       "display_name": "Molecular Basis of Rett Syndrome and Related Disorders"
     },
     {
       "id": "https://openalex.org/T13984",
       "display_name": "Nutritional Genomics: Personalized Nutrition and Health"
     },
     {
       "id": "https://openalex.org/T12447",
       "display_name": "Phylogenetic Analysis of Spiders and Their Evolution"
     },
     {
       "id": "https://openalex.org/T10012",
       "display_name": "Population Genetic Structure and Dynamics"
     },
     {
       "id": "https://openalex.org/T12749",
       "display_name": "Race and Genetics in Biomedical Research"
     },
     {
       "id": "https://openalex.org/T11077",
       "display_name": "Sex Determination and Differentiation in Organisms"
     },
     {
       "id": "https://openalex.org/T11353",
       "display_name": "Snake Venom Evolution and Toxinology"
     },
     {
       "id": "https://openalex.org/T11642",
       "display_name": "Standards and Guidelines for Genetic Variant Interpretation"
     },
     {
       "id": "https://openalex.org/T12929",
       "display_name": "Transgenic Animal Research"
     }
   ],
   "subfield": {
     "id": "https://openalex.org/subfields/1311",
     "display_name": "Genetics"
   },
   "updated_date": "2024-08-19T06:16:02.866040",
   "works_count": 45663,
   "oa_id": "T11310"
 }

}