Item talk:Q166959

From geokb

{

 "OpenAlex": {
   "display_name": "Lysosomal Calcium Signaling in Physiology and Pathology",
   "description": "This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.",
   "keywords": [
     "Lysosomal Calcium Signaling",
     "Two-pore Channels",
     "NAADP",
     "TRPML1",
     "Endolysosomal Trafficking",
     "Cyclic ADP-Ribose",
     "Mucolipidosis Type IV",
     "Intracellular Calcium Release",
     "Nicotinic Acid Adenine Dinucleotide Phosphate",
     "Lysosomal Storage Diseases"
   ],
   "ids": {
     "openalex": "https://openalex.org/T13415",
     "wikipedia": "https://en.wikipedia.org/wiki/Lysosomal_calcium_signaling"
   },
   "subfield": {
     "id": "https://openalex.org/subfields/1314",
     "display_name": "Physiology"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "updated_date": "2024-08-12T05:18:46.035266",
   "created_date": "2024-01-23",
   "type": "topic",
   "oa_id": "T13415",
   "id": "https://openalex.org/T13415"
 }

}