Item talk:Q168197

{

 "OpenAlex": {
   "cited_by_count": 1659660,
   "created_date": "2024-01-23",
   "description": "This cluster of papers focuses on the molecular mechanisms of Ras signaling pathways, including the role of protein kinases, GTPases, and phospholipase C in cell regulation and cancer therapy. It explores the involvement of calcium signaling, cell migration, and transcriptional regulation in oncogenic mutations.",
   "display_name": "Molecular Mechanisms of Ras Signaling Pathways",
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "id": "https://openalex.org/T10169",
   "ids": {
     "openalex": "https://openalex.org/T10169",
     "wikipedia": "https://en.wikipedia.org/wiki/Ras_signaling"
   },
   "keywords": [
     "Ras Signaling",
     "Protein Kinases",
     "GTPases",
     "Cell Regulation",
     "Cancer Therapy",
     "Calcium Signaling",
     "Phospholipase C",
     "Cell Migration",
     "Oncogenic Mutations",
     "Transcriptional Regulation"
   ],
   "siblings": [
     {
       "id": "https://openalex.org/T13526",
       "display_name": "14-3-3 Proteins: Structure, Function, and Regulation"
     },
     {
       "id": "https://openalex.org/T10836",
       "display_name": "Advances in Metabolomics Research"
     },
     {
       "id": "https://openalex.org/T10887",
       "display_name": "Analysis of Gene Interaction Networks"
     },
     {
       "id": "https://openalex.org/T12763",
       "display_name": "ATP Synthase Function and Regulation"
     },
     {
       "id": "https://openalex.org/T10593",
       "display_name": "Bacterial Biofilms and Quorum Sensing Mechanisms"
     },
     {
       "id": "https://openalex.org/T12685",
       "display_name": "Bioactive Limonoids in Medicinal Plants"
     },
     {
       "id": "https://openalex.org/T11561",
       "display_name": "Bioactive Peptides in Food and Health"
     },
     {
       "id": "https://openalex.org/T12215",
       "display_name": "Bioactivity of Steroidal Saponins in Medicinal Plants"
     },
     {
       "id": "https://openalex.org/T13188",
       "display_name": "Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids"
     },
     {
       "id": "https://openalex.org/T13725",
       "display_name": "Biochemistry, Pharmacology, and Medical Use of Bromelain"
     },
     {
       "id": "https://openalex.org/T11765",
       "display_name": "Biogenesis and Functions of Circular RNAs"
     },
     {
       "id": "https://openalex.org/T12530",
       "display_name": "Biological Activities of Diterpenoids from Medicinal Plants"
     },
     {
       "id": "https://openalex.org/T13454",
       "display_name": "Biological Activities of Phenothiazines and Related Compounds"
     },
     {
       "id": "https://openalex.org/T12257",
       "display_name": "Biological Activities of Prenylated Flavonoids"
     },
     {
       "id": "https://openalex.org/T11385",
       "display_name": "Biological Activities of Triterpenoids and Saponins"
     },
     {
       "id": "https://openalex.org/T13221",
       "display_name": "Biological Activity of Diterpenoids and Biflavonoids"
     },
     {
       "id": "https://openalex.org/T11515",
       "display_name": "Biological Agents for Bioterrorism"
     },
     {
       "id": "https://openalex.org/T12688",
       "display_name": "Biological Methane Utilization and Metabolism"
     },
     {
       "id": "https://openalex.org/T12561",
       "display_name": "Bioluminescence Imaging and Reporter Systems"
     },
     {
       "id": "https://openalex.org/T11710",
       "display_name": "Biomedical Ontologies and Text Mining"
     },
     {
       "id": "https://openalex.org/T11882",
       "display_name": "Biosynthesis and Engineering of Terpenoids"
     },
     {
       "id": "https://openalex.org/T12360",
       "display_name": "Biosynthesis and Pharmacological Activities of Lignans"
     },
     {
       "id": "https://openalex.org/T12620",
       "display_name": "Calcineurin-NFAT Signaling in Transcriptional Regulation"
     },
     {
       "id": "https://openalex.org/T13937",
       "display_name": "Challenges and Innovations in Bioinformatics Education"
     },
     {
       "id": "https://openalex.org/T12683",
       "display_name": "Chitin Metabolism in Insects and Mammals"
     },
     {
       "id": "https://openalex.org/T12820",
       "display_name": "Chromatin Remodeling in Cancer and Development"
     },
     {
       "id": "https://openalex.org/T10878",
       "display_name": "Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins"
     },
     {
       "id": "https://openalex.org/T11289",
       "display_name": "Comprehensive Integration of Single-Cell Transcriptomic Data"
     },
     {
       "id": "https://openalex.org/T13326",
       "display_name": "Cyclotide Bioengineering and Protein Anchoring Mechanisms"
     },
     {
       "id": "https://openalex.org/T10066",
       "display_name": "Diversity and Function of Gut Microbiome"
     },
     {
       "id": "https://openalex.org/T12668",
       "display_name": "Diversity and Systematics of Yeasts"
     },
     {
       "id": "https://openalex.org/T12388",
       "display_name": "DNA Barcoding for Food Authentication and Fraud Detection"
     },
     {
       "id": "https://openalex.org/T10207",
       "display_name": "DNA Nanotechnology and Bioanalytical Applications"
     },
     {
       "id": "https://openalex.org/T11845",
       "display_name": "DNA Topoisomerases: Structure, Function, and Inhibition"
     },
     {
       "id": "https://openalex.org/T12029",
       "display_name": "DNA-based Computing and Data Storage"
     },
     {
       "id": "https://openalex.org/T10240",
       "display_name": "Elicitor Signal Transduction for Metabolite Production"
     },
     {
       "id": "https://openalex.org/T10404",
       "display_name": "Enzyme Immobilization Techniques"
     },
     {
       "id": "https://openalex.org/T10269",
       "display_name": "Epigenetic Modifications and Their Functional Implications"
     },
     {
       "id": "https://openalex.org/T10773",
       "display_name": "Exosome Biology and Function in Intercellular Communication"
     },
     {
       "id": "https://openalex.org/T12287",
       "display_name": "Fibroblast Growth Factor Signaling Pathway"
     },
     {
       "id": "https://openalex.org/T12610",
       "display_name": "Functions and Regulation of RNA Editing by ADARs"
     },
     {
       "id": "https://openalex.org/T10432",
       "display_name": "G-Quadruplex DNA Structures and Functions"
     },
     {
       "id": "https://openalex.org/T10497",
       "display_name": "Genomic Expression and Function in Yeast Organism"
     },
     {
       "id": "https://openalex.org/T12946",
       "display_name": "Genomic Signal Processing and Analysis Techniques"
     },
     {
       "id": "https://openalex.org/T11879",
       "display_name": "Global Diversity of Microbial Eukaryotes and Their Evolution"
     },
     {
       "id": "https://openalex.org/T10602",
       "display_name": "Glycosylation in Health and Disease"
     },
     {
       "id": "https://openalex.org/T12009",
       "display_name": "Hedgehog Signaling in Development and Cancer"
     },
     {
       "id": "https://openalex.org/T11848",
       "display_name": "Heme Oxygenase and Carbon Monoxide Research"
     },
     {
       "id": "https://openalex.org/T10505",
       "display_name": "Induction and Differentiation of Pluripotent Stem Cells"
     },
     {
       "id": "https://openalex.org/T10407",
       "display_name": "Lipid Rafts and Membrane Dynamics"
     },
     {
       "id": "https://openalex.org/T11786",
       "display_name": "Magnetosome Formation in Prokaryotes"
     },
     {
       "id": "https://openalex.org/T11533",
       "display_name": "Mammalian MAP Kinase Signaling Pathways"
     },
     {
       "id": "https://openalex.org/T10725",
       "display_name": "Mechanisms and Applications of RNA Interference"
     },
     {
       "id": "https://openalex.org/T10932",
       "display_name": "Metabolic Engineering and Synthetic Biology"
     },
     {
       "id": "https://openalex.org/T13012",
       "display_name": "Metabolism and Functions of Coenzyme Q"
     },
     {
       "id": "https://openalex.org/T10885",
       "display_name": "Microarray Data Analysis and Gene Expression Profiling"
     },
     {
       "id": "https://openalex.org/T14285",
       "display_name": "Microbial Production of Polyglutamic Acid"
     },
     {
       "id": "https://openalex.org/T13736",
       "display_name": "Microbial Transformation of Steroids"
     },
     {
       "id": "https://openalex.org/T10301",
       "display_name": "Mitochondrial Dynamics and Reactive Oxygen Species Regulation"
     },
     {
       "id": "https://openalex.org/T11956",
       "display_name": "Molecular Biology of Steroidogenesis and Disorders"
     },
     {
       "id": "https://openalex.org/T10934",
       "display_name": "Molecular Chaperones in Protein Folding and Disease"
     },
     {
       "id": "https://openalex.org/T11889",
       "display_name": "Molecular Mechanisms and Medical Applications of Ginseng"
     },
     {
       "id": "https://openalex.org/T11305",
       "display_name": "Molecular Mechanisms of Amyloidosis"
     },
     {
       "id": "https://openalex.org/T10422",
       "display_name": "Molecular Mechanisms of Angiogenesis and Vascular Function"
     },
     {
       "id": "https://openalex.org/T10294",
       "display_name": "Molecular Mechanisms of Apoptosis and Cell Death"
     },
     {
       "id": "https://openalex.org/T10724",
       "display_name": "Molecular Mechanisms of Aquaporins in Physiology and Disease"
     },
     {
       "id": "https://openalex.org/T11677",
       "display_name": "Molecular Mechanisms of Cardiac Development and Regeneration"
     },
     {
       "id": "https://openalex.org/T10123",
       "display_name": "Molecular Mechanisms of DNA Damage Response"
     },
     {
       "id": "https://openalex.org/T11237",
       "display_name": "Molecular Mechanisms of Flavonoid Biosynthesis in Plants"
     },
     {
       "id": "https://openalex.org/T12441",
       "display_name": "Molecular Mechanisms of Heme Biosynthesis and Related Disorders"
     },
     {
       "id": "https://openalex.org/T11078",
       "display_name": "Molecular Mechanisms of Inflammasome Activation and Regulation"
     },
     {
       "id": "https://openalex.org/T11075",
       "display_name": "Molecular Mechanisms of Insect Resistance to Xenobiotics"
     },
     {
       "id": "https://openalex.org/T10493",
       "display_name": "Molecular Mechanisms of Ion Channels Regulation"
     },
     {
       "id": "https://openalex.org/T12140",
       "display_name": "Molecular Mechanisms of Kidney Development and Disease"
     },
     {
       "id": "https://openalex.org/T13437",
       "display_name": "Molecular Mechanisms of Metastasis Suppressor Genes"
     },
     {
       "id": "https://openalex.org/T10441",
       "display_name": "Molecular Mechanisms of Muscle Regeneration and Atrophy"
     },
     {
       "id": "https://openalex.org/T11219",
       "display_name": "Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling"
     },
     {
       "id": "https://openalex.org/T10303",
       "display_name": "Molecular Mechanisms of Photosynthesis and Photoprotection"
     },
     {
       "id": "https://openalex.org/T12789",
       "display_name": "Molecular Mechanisms of Planarian Regeneration"
     },
     {
       "id": "https://openalex.org/T11927",
       "display_name": "Molecular Mechanisms of Pollen Development and Function"
     },
     {
       "id": "https://openalex.org/T10691",
       "display_name": "Molecular Mechanisms of Retinal Degeneration and Regeneration"
     },
     {
       "id": "https://openalex.org/T11919",
       "display_name": "Molecular Mechanisms of Tooth Development and Morphogenesis"
     },
     {
       "id": "https://openalex.org/T12434",
       "display_name": "Molecular Regulation and Clinical Applications of PDEs"
     },
     {
       "id": "https://openalex.org/T12566",
       "display_name": "Molecular Regulation of Sulfur Metabolism in Plants"
     },
     {
       "id": "https://openalex.org/T14049",
       "display_name": "Molecular Systematics of Gesneriaceae and Allies"
     },
     {
       "id": "https://openalex.org/T10952",
       "display_name": "mTOR Signaling in Growth and Disease"
     },
     {
       "id": "https://openalex.org/T10268",
       "display_name": "Notch Signaling Pathway in Development and Disease"
     },
     {
       "id": "https://openalex.org/T12827",
       "display_name": "Nucleotide Metabolism and Enzyme Regulation"
     },
     {
       "id": "https://openalex.org/T14135",
       "display_name": "Oxidation States in Biochemistry and Medicine"
     },
     {
       "id": "https://openalex.org/T10911",
       "display_name": "Peptide Synthesis and Drug Discovery"
     },
     {
       "id": "https://openalex.org/T11072",
       "display_name": "Peroxisome Proliferator-Activated Receptors"
     },
     {
       "id": "https://openalex.org/T11924",
       "display_name": "Polyamines and Biogenic Amines in Biology and Health"
     },
     {
       "id": "https://openalex.org/T12576",
       "display_name": "Prediction of Peptide-MHC Binding Affinity"
     },
     {
       "id": "https://openalex.org/T12254",
       "display_name": "Prediction of Protein Subcellular Localization"
     },
     {
       "id": "https://openalex.org/T11335",
       "display_name": "Prion Diseases: Causes and Molecular Basis"
     },
     {
       "id": "https://openalex.org/T11124",
       "display_name": "Protein Aggregation and Biopharmaceutical Stability"
     },
     {
       "id": "https://openalex.org/T13157",
       "display_name": "Protein Arginine Methylation in Mammals"
     },
     {
       "id": "https://openalex.org/T11908",
       "display_name": "Protein Binding Specificity in Human Serum Albumin"
     },
     {
       "id": "https://openalex.org/T12867",
       "display_name": "Protein Microarray Technology and Applications"
     },
     {
       "id": "https://openalex.org/T10044",
       "display_name": "Protein Structure Prediction and Analysis"
     },
     {
       "id": "https://openalex.org/T12104",
       "display_name": "Protein Tyrosine Phosphatases in Human Health and Disease"
     },
     {
       "id": "https://openalex.org/T13187",
       "display_name": "Protein-DNA Interaction Dynamics in Living Cells"
     },
     {
       "id": "https://openalex.org/T12756",
       "display_name": "Pyrrolizidine Alkaloids: Toxicity, Metabolism, and Health Implications"
     },
     {
       "id": "https://openalex.org/T11970",
       "display_name": "Real-Time Polymerase Chain Reaction"
     },
     {
       "id": "https://openalex.org/T11663",
       "display_name": "Recombinant Protein Production in Mammalian and Insect Cells"
     },
     {
       "id": "https://openalex.org/T11884",
       "display_name": "Redox Signaling and Oxidative Stress"
     },
     {
       "id": "https://openalex.org/T12835",
       "display_name": "Regulation and Functions of FoxO Transcription Factors"
     },
     {
       "id": "https://openalex.org/T10222",
       "display_name": "Regulation of Chromatin Structure and Function"
     },
     {
       "id": "https://openalex.org/T10604",
       "display_name": "Regulation of RNA Processing and Function"
     },
     {
       "id": "https://openalex.org/T13651",
       "display_name": "Research on Rhodiola rosea and Salidroside"
     },
     {
       "id": "https://openalex.org/T14065",
       "display_name": "Research on Synthetic Phosphoethanolamine and its Effects"
     },
     {
       "id": "https://openalex.org/T10521",
       "display_name": "Ribosome Structure and Translation Mechanisms"
     },
     {
       "id": "https://openalex.org/T11482",
       "display_name": "RNA Methylation and Modification in Gene Expression"
     },
     {
       "id": "https://openalex.org/T10015",
       "display_name": "RNA Sequencing Data Analysis"
     },
     {
       "id": "https://openalex.org/T11339",
       "display_name": "Role of AMP-Activated Protein Kinase in Cellular Metabolism"
     },
     {
       "id": "https://openalex.org/T12412",
       "display_name": "Role of Carbonic Anhydrases in Medicine and Biotechnology"
     },
     {
       "id": "https://openalex.org/T13223",
       "display_name": "Role of CCN Proteins in Signaling Pathways"
     },
     {
       "id": "https://openalex.org/T12187",
       "display_name": "Role of Glutathione in Oxidative Stress Response"
     },
     {
       "id": "https://openalex.org/T11736",
       "display_name": "Role of Histone Deacetylases in Cellular Regulation"
     },
     {
       "id": "https://openalex.org/T11332",
       "display_name": "Role of Nrf2 Signaling in Oxidative Stress Response"
     },
     {
       "id": "https://openalex.org/T11559",
       "display_name": "Role of Retinoic Acid in Biological Processes"
     },
     {
       "id": "https://openalex.org/T13047",
       "display_name": "Role of Sigma Receptors in Cellular Signaling"
     },
     {
       "id": "https://openalex.org/T13426",
       "display_name": "Role of Transcription Factors in Cell Regulation"
     },
     {
       "id": "https://openalex.org/T12030",
       "display_name": "S100 Proteins: Structure, Function, and Pathology"
     },
     {
       "id": "https://openalex.org/T11308",
       "display_name": "Sphingolipid Signalling and Metabolism in Health and Disease"
     },
     {
       "id": "https://openalex.org/T10621",
       "display_name": "Stochasticity in Gene Regulatory Networks"
     },
     {
       "id": "https://openalex.org/T11178",
       "display_name": "Structure and Function of G Protein-Coupled Receptors"
     },
     {
       "id": "https://openalex.org/T11480",
       "display_name": "Structure and Function of Gap Junctions and Connexins"
     },
     {
       "id": "https://openalex.org/T11818",
       "display_name": "Structure and Function of Nicotinic Receptors"
     },
     {
       "id": "https://openalex.org/T11841",
       "display_name": "Structure and Function of the Nuclear Pore Complex"
     },
     {
       "id": "https://openalex.org/T12534",
       "display_name": "Targeted Protein Degradation in Biomedical Research"
     },
     {
       "id": "https://openalex.org/T11501",
       "display_name": "Transforming Growth Factor Beta Signaling Pathway"
     },
     {
       "id": "https://openalex.org/T11041",
       "display_name": "Ubiquitin-Proteasome Proteolytic Pathway"
     },
     {
       "id": "https://openalex.org/T10929",
       "display_name": "Wnt Signaling in Development and Disease"
     }
   ],
   "subfield": {
     "id": "https://openalex.org/subfields/1312",
     "display_name": "Molecular Biology"
   },
   "updated_date": "2024-08-19T05:20:29.770100",
   "works_count": 32716,
   "oa_id": "T10169"
 }

}