Item talk:Q166959

{

 "id": "https://openalex.org/T13415",
 "display_name": "Lysosomal Calcium Signaling in Physiology and Pathology",
 "description": "This cluster of papers explores the evolution, function, and dysregulation of lysosomal calcium signaling, focusing on the role of two-pore channels, NAADP, TRPML1, and cyclic ADP-ribose in intracellular calcium release and endolysosomal trafficking. It also investigates the implications of these mechanisms in diseases such as mucolipidosis type IV and lysosomal storage disorders.",
 "keywords": [
   "Lysosomal Calcium Signaling",
   "Two-pore Channels",
   "NAADP",
   "TRPML1",
   "Endolysosomal Trafficking",
   "Cyclic ADP-Ribose",
   "Mucolipidosis Type IV",
   "Intracellular Calcium Release",
   "Nicotinic Acid Adenine Dinucleotide Phosphate",
   "Lysosomal Storage Diseases"
 ],
 "ids": {
   "openalex": "https://openalex.org/T13415",
   "wikipedia": "https://en.wikipedia.org/wiki/Lysosomal_calcium_signaling"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/1314",
   "display_name": "Physiology"
 },
 "field": {
   "id": "https://openalex.org/fields/13",
   "display_name": "Biochemistry, Genetics and Molecular Biology"
 },
 "domain": {
   "id": "https://openalex.org/domains/1",
   "display_name": "Life Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T12976",
     "display_name": "Influence of Magnetic Fields on Biological Systems"
   },
   {
     "id": "https://openalex.org/T11193",
     "display_name": "Molecular Physiology of Purinergic Signalling"
   },
   {
     "id": "https://openalex.org/T11505",
     "display_name": "Reproductive Physiology and Endocrine Disruption in Fish"
   }
 ],
 "works_count": 9663,
 "cited_by_count": 288243,
 "updated_date": "2024-08-26T05:32:36.297173",
 "created_date": "2024-01-23"

}