Item talk:Q267618
From geokb
{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Interlaboratory comparison of SARS-CoV2 molecular detection assays in use by U.S. veterinary diagnostic laboratories",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70223505",
"url": "https://pubs.usgs.gov/publication/70223505"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70223505
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1177/10406387211029913",
"url": "https://doi.org/10.1177/10406387211029913"
}
],
"journal": {
"@type": "Periodical",
"name": "Journal of Veterinary Diagnostic Investigation",
"volumeNumber": "33",
"issueNumber": "6"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Journal of Veterinary Diagnostic Investigation"
}
],
"datePublished": "2021",
"dateModified": "2021-11-01",
"abstract": "The continued search for intermediate hosts and potential reservoirs for SARS-CoV2 makes it clear that animal surveillance is critical in outbreak response and prevention. Real-time RT-PCR assays for SARS-CoV2 detection can easily be adapted to different host species. U.S. veterinary diagnostic laboratories have used the CDC assays or other national reference laboratory methods to test animal samples. However, these methods have only been evaluated using internal validation protocols. To help the laboratories evaluate their SARS-CoV2 test methods, an interlaboratory comparison (ILC) was performed in collaboration with multiple organizations. Forty-four sets of 19 blind-coded RNA samples in Tris-EDTA (TE) buffer or PrimeStore transport medium were shipped to 42 laboratories. Results were analyzed according to the principles of the International Organization for Standardization (ISO) 16140-2:2016 standard. Qualitative assessment of PrimeStore samples revealed that, in approximately two-thirds of the laboratories, the limit of detection with a probability of 0.95 (LOD95) for detecting the RNA was \u226420 copies per PCR reaction, close to the theoretical LOD of 3 copies per reaction. This level of sensitivity is not expected in clinical samples because of additional factors, such as sample collection, transport, and extraction of RNA from the clinical matrix. Quantitative assessment of Ct values indicated that reproducibility standard deviations for testing the RNA with assays reported as N1 were slightly lower than those for N2, and they were higher for the RNA in PrimeStore medium than those in TE buffer. Analyst experience and the use of either a singleplex or multiplex PCR also affected the quantitative ILC test results.",
"description": "13 p.",
"publisher": {
"@type": "Organization",
"name": "Sage Journals"
},
"author": [
{
"@type": "Person",
"name": "Reimshuessel, Renate",
"givenName": "Renate",
"familyName": "Reimshuessel",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Center for Veterinary Medicine, 8401 Muirkirk Rd., Laurel, MD 20708"
}
]
},
{
"@type": "Person",
"name": "Reddy, Ravinder",
"givenName": "Ravinder",
"familyName": "Reddy",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Division of Food Processing Science and Technology, 6502 S. Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Schlier, Anja",
"givenName": "Anja",
"familyName": "Schlier",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
},
{
"@type": "Person",
"name": "Nichani, Kapil",
"givenName": "Kapil",
"familyName": "Nichani",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
},
{
"@type": "Person",
"name": "Hettwer, Karina",
"givenName": "Karina",
"familyName": "Hettwer",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
},
{
"@type": "Person",
"name": "Kmet, Matthew",
"givenName": "Matthew",
"familyName": "Kmet",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Division of Food Processing Science and Technology, 6502 S. Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Newkirk, Robert",
"givenName": "Robert",
"familyName": "Newkirk",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Division of Food Processing Science and Technology, 6502 S. Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Pickens, Shannon",
"givenName": "Shannon",
"familyName": "Pickens",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Division of Food Processing Science and Technology, 6502 S. Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Ulaszek, Jodie",
"givenName": "Jodie",
"familyName": "Ulaszek",
"affiliation": [
{
"@type": "Organization",
"name": "Illinois Institute of Technology, Institute for Food Safety and Health, 6502 South Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Nemser, Sarah",
"givenName": "Sarah",
"familyName": "Nemser",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Center for Veterinary Medicine, 8401 Muirkirk Rd., Laurel, MD 20708"
}
]
},
{
"@type": "Person",
"name": "Goodman, Laura",
"givenName": "Laura",
"familyName": "Goodman",
"affiliation": [
{
"@type": "Organization",
"name": "Cornell University"
}
]
},
{
"@type": "Person",
"name": "Killian, Mary Lea",
"givenName": "Mary Lea",
"familyName": "Killian",
"affiliation": [
{
"@type": "Organization",
"name": "National Veterinary Services Laboratories, USDA-APHIS, Ames, Iowa 50010, USA"
}
]
},
{
"@type": "Person",
"name": "Ip, Hon S.",
"givenName": "Hon S.",
"familyName": "Ip",
"identifier": {
"@type": "PropertyValue",
"propertyID": "ORCID",
"value": "0000-0003-4844-7533",
"url": "https://orcid.org/0000-0003-4844-7533"
},
"affiliation": [
{
"@type": "Organization",
"name": "National Wildlife Health Center",
"url": "https://www.usgs.gov/centers/nwhc"
}
]
},
{
"@type": "Person",
"name": "Uhlig, Steffen",
"givenName": "Steffen",
"familyName": "Uhlig",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
},
{
"@type": "Person",
"name": "Deng, Kaiping",
"givenName": "Kaiping",
"familyName": "Deng",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Division of Food Processing Science and Technology, 6502 S. Archer Road, Bedford Park, IL 60501"
}
]
},
{
"@type": "Person",
"name": "Colson, Bertrand",
"givenName": "Bertrand",
"familyName": "Colson",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
},
{
"@type": "Person",
"name": "Tkachenko, Andriy",
"givenName": "Andriy",
"familyName": "Tkachenko",
"affiliation": [
{
"@type": "Organization",
"name": "U.S. Food and Drug Administration, Center for Veterinary Medicine, 8401 Muirkirk Rd., Laurel, MD 20708"
}
]
},
{
"@type": "Person",
"name": "Frost, Kirsten",
"givenName": "Kirsten",
"familyName": "Frost",
"affiliation": [
{
"@type": "Organization",
"name": "2QuoData \u2013 Quality & Statistics, Prellerstr. 14, 01309, Dresden, Germany"
}
]
}
],
"funder": [
{
"@type": "Organization",
"name": "National Wildlife Health Center",
"url": "https://www.usgs.gov/centers/nwhc"
}
]
},
"OpenAlex": {
"_id": "https://openalex.org/w3185981165",
"abstract_inverted_index": {
"The": [
0
],
"continued": [
1
],
"search": [
2
],
"for": [
3,
9,
27,
119,
147,
204,
218,
224
],
"intermediate": [
4
],
"hosts": [
5
],
"and": [
6,
22,
186,
220,
237
],
"potential": [
7
],
"reservoirs": [
8
],
"SARS-CoV2": [
10,
28,
74
],
"makes": [
11
],
"it": [
12
],
"clear": [
13
],
"that": [
14,
200
],
"animal": [
15,
55
],
"surveillance": [
16
],
"is": [
17,
171
],
"critical": [
18
],
"in": [
19,
83,
95,
131,
174,
227,
232
],
"outbreak": [
20
],
"response": [
21
],
"prevention.": [
23
],
"Real-time": [
24
],
"RT-PCR": [
25
],
"assays": [
26,
46,
209
],
"detection": [
29,
140
],
"can": [
30
],
"easily": [
31
],
"be": [
32
],
"adapted": [
33
],
"to": [
34,
53,
105,
112,
158
],
"different": [
35
],
"host": [
36
],
"species.": [
37
],
"U.S.": [
38
],
"veterinary": [
39
],
"diagnostic": [
40
],
"laboratories": [
41,
71
],
"have": [
42,
60
],
"used": [
43
],
"the": [
44,
70,
113,
116,
135,
137,
149,
159,
191,
206,
225,
238,
249
],
"CDC": [
45
],
"or": [
47,
99,
244
],
"other": [
48
],
"national": [
49
],
"reference": [
50
],
"laboratory": [
51
],
"methods": [
52,
59
],
"test": [
54,
75,
252
],
"samples.": [
56
],
"However,": [
57
],
"these": [
58
],
"only": [
61
],
"been": [
62
],
"evaluated": [
63
],
"using": [
64
],
"internal": [
65
],
"validation": [
66
],
"protocols.": [
67
],
"To": [
68
],
"help": [
69
],
"evaluate": [
72
],
"their": [
73
],
"methods,": [
76
],
"an": [
77
],
"interlaboratory": [
78
],
"comparison": [
79
],
"(ILC)": [
80
],
"was": [
81,
151
],
"performed": [
82
],
"collaboration": [
84
],
"with": [
85,
141,
208
],
"multiple": [
86
],
"organizations.": [
87
],
"Forty-four": [
88
],
"sets": [
89
],
"of": [
90,
115,
126,
134,
139,
144,
162,
169,
178,
188,
196,
240
],
"19": [
91
],
"blind-coded": [
92
],
"RNA": [
93,
150,
189,
207,
226
],
"samples": [
94,
128,
176
],
"Tris-EDTA": [
96
],
"(TE)": [
97
],
"buffer": [
98
],
"PrimeStore": [
100,
127,
228
],
"transport": [
101
],
"medium": [
102,
229
],
"were": [
103,
109,
213,
222
],
"shipped": [
104
],
"42": [
106
],
"laboratories.": [
107
],
"Results": [
108
],
"analyzed": [
110
],
"according": [
111
],
"principles": [
114
],
"International": [
117
],
"Organization": [
118
],
"Standardization": [
120
],
"(ISO)": [
121
],
"16140-2:2016": [
122
],
"standard.": [
123
],
"Qualitative": [
124
],
"assessment": [
125,
195
],
"revealed": [
129
],
"that,": [
130
],
"approximately": [
132
],
"two-thirds": [
133
],
"laboratories,": [
136
],
"limit": [
138
],
"a": [
142,
242
],
"probability": [
143
],
"0.95": [
145
],
"(LOD95)": [
146
],
"detecting": [
148
],
"\u226420": [
152
],
"copies": [
153,
164
],
"per": [
154,
165
],
"PCR": [
155,
246
],
"reaction,": [
156
],
"close": [
157
],
"theoretical": [
160
],
"LOD": [
161
],
"3": [
163
],
"reaction.": [
166
],
"This": [
167
],
"level": [
168
],
"sensitivity": [
170
],
"not": [
172
],
"expected": [
173
],
"clinical": [
175,
192
],
"because": [
177
],
"additional": [
179
],
"factors,": [
180
],
"such": [
181
],
"as": [
182,
211
],
"sample": [
183
],
"collection,": [
184
],
"transport,": [
185
],
"extraction": [
187
],
"from": [
190
],
"matrix.": [
193
],
"Quantitative": [
194
],
"Ct": [
197
],
"values": [
198
],
"indicated": [
199
],
"reproducibility": [
201
],
"standard": [
202
],
"deviations": [
203
],
"testing": [
205
],
"reported": [
210
],
"N1": [
212
],
"slightly": [
214
],
"lower": [
215
],
"than": [
216,
230
],
"those": [
217,
231
],
"N2,": [
219
],
"they": [
221
],
"higher": [
223
],
"TE": [
233
],
"buffer.": [
234
],
"Analyst": [
235
],
"experience": [
236
],
"use": [
239
],
"either": [
241
],
"singleplex": [
243
],
"multiplex": [
245
],
"also": [
247
],
"affected": [
248
],
"quantitative": [
250
],
"ILC": [
251
],
"results.": [
253
]
},
"apc_list": null,
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5103281395",
"display_name": "Kaiping Deng",
"orcid": "https://orcid.org/0000-0001-7700-5393"
},
"institutions": [
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Kaiping Deng",
"raw_affiliation_strings": [
"Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA",
"institution_ids": [
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5006443757",
"display_name": "Steffen Uhlig",
"orcid": "https://orcid.org/0000-0001-8700-8686"
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Steffen Uhlig",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5084311164",
"display_name": "Hon S. Ip",
"orcid": "https://orcid.org/0000-0003-4844-7533"
},
"institutions": [
{
"id": "https://openalex.org/I4210131920",
"display_name": "National Wildlife Health Center",
"ror": "https://ror.org/038d10y34",
"country_code": "US",
"type": "healthcare",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249",
"https://openalex.org/I4210131920"
]
},
{
"id": "https://openalex.org/I1286329397",
"display_name": "United States Geological Survey",
"ror": "https://ror.org/035a68863",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1286329397",
"https://openalex.org/I1335927249"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Hon S. Ip",
"raw_affiliation_strings": [
"National Wildlife Health Center, U.S. Geological Survey, Madison, WI, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Wildlife Health Center, U.S. Geological Survey, Madison, WI, USA",
"institution_ids": [
"https://openalex.org/I4210131920",
"https://openalex.org/I1286329397"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5045734979",
"display_name": "Mary Lea Killian",
"orcid": "https://orcid.org/0000-0002-8613-2009"
},
"institutions": [
{
"id": "https://openalex.org/I1288380561",
"display_name": "Animal and Plant Health Inspection Service",
"ror": "https://ror.org/0599wfz09",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1288380561",
"https://openalex.org/I1336096307"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Mary Lea Killian",
"raw_affiliation_strings": [
"National Animal and Plant Health Inspection Service Laboratories, Veterinary Services, U.S. Department of Agriculture, Ames, IA, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Animal and Plant Health Inspection Service Laboratories, Veterinary Services, U.S. Department of Agriculture, Ames, IA, USA",
"institution_ids": [
"https://openalex.org/I1288380561"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5070784467",
"display_name": "Laura B. Goodman",
"orcid": "https://orcid.org/0000-0002-8327-3092"
},
"institutions": [
{
"id": "https://openalex.org/I205783295",
"display_name": "Cornell University",
"ror": "https://ror.org/05bnh6r87",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I205783295"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Laura B. Goodman",
"raw_affiliation_strings": [
"College of Veterinary Medicine, Cornell University, Ithaca, NY, USA"
],
"affiliations": [
{
"raw_affiliation_string": "College of Veterinary Medicine, Cornell University, Ithaca, NY, USA",
"institution_ids": [
"https://openalex.org/I205783295"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5060211996",
"display_name": "Sarah M. Nemser",
"orcid": "https://orcid.org/0000-0002-0710-0050"
},
"institutions": [
{
"id": "https://openalex.org/I1319408584",
"display_name": "Center for Veterinary Medicine",
"ror": "https://ror.org/02y55wr53",
"country_code": "US",
"type": "facility",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1319408584",
"https://openalex.org/I1320320070"
]
},
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Sarah Nemser",
"raw_affiliation_strings": [
"Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, USA",
"institution_ids": [
"https://openalex.org/I1319408584",
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5065235954",
"display_name": "Jodie Ulaszek",
"orcid": "https://orcid.org/0009-0000-0946-0722"
},
"institutions": [
{
"id": "https://openalex.org/I4210096483",
"display_name": "Institute for Food Safety and Health",
"ror": "https://ror.org/00wjdp131",
"country_code": "US",
"type": "facility",
"lineage": [
"https://openalex.org/I4210096483"
]
},
{
"id": "https://openalex.org/I180949307",
"display_name": "Illinois Institute of Technology",
"ror": "https://ror.org/037t3ry66",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I180949307"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Jodie Ulaszek",
"raw_affiliation_strings": [
"Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Institute for Food Safety and Health, Illinois Institute of Technology, Bedford Park, IL, USA",
"institution_ids": [
"https://openalex.org/I4210096483",
"https://openalex.org/I180949307"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5072774369",
"display_name": "Shannon Pickens",
"orcid": null
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Shannon Pickens",
"raw_affiliation_strings": [],
"affiliations": []
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5005040656",
"display_name": "Robert Newkirk",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Robert Newkirk",
"raw_affiliation_strings": [
"Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA",
"institution_ids": [
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5081258522",
"display_name": "Matthew Kmet",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Matthew Kmet",
"raw_affiliation_strings": [
"Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA",
"institution_ids": [
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5035220133",
"display_name": "Kirstin Frost",
"orcid": null
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Kirstin Frost",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5033869007",
"display_name": "Karina Hettwer",
"orcid": null
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Karina Hettwer",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5000181582",
"display_name": "Bertrand Colson",
"orcid": "https://orcid.org/0000-0003-4743-1150"
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Bertrand Colson",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5007879619",
"display_name": "Kapil Nichani",
"orcid": null
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Kapil Nichani",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5020353267",
"display_name": "Anja Schlierf",
"orcid": "https://orcid.org/0000-0002-9955-557X"
},
"institutions": [],
"countries": [
"DE"
],
"is_corresponding": false,
"raw_author_name": "Anja Schlierf",
"raw_affiliation_strings": [
"QuoData\u2013Quality & Statistics, Dresden, Germany"
],
"affiliations": [
{
"raw_affiliation_string": "QuoData\u2013Quality & Statistics, Dresden, Germany",
"institution_ids": []
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5062994171",
"display_name": "Andriy Tkachenko",
"orcid": "https://orcid.org/0000-0002-0048-9243"
},
"institutions": [
{
"id": "https://openalex.org/I1319408584",
"display_name": "Center for Veterinary Medicine",
"ror": "https://ror.org/02y55wr53",
"country_code": "US",
"type": "facility",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1319408584",
"https://openalex.org/I1320320070"
]
},
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Andriy Tkachenko",
"raw_affiliation_strings": [
"Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD, USA",
"institution_ids": [
"https://openalex.org/I1319408584",
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5039226617",
"display_name": "Ravinder Reddy",
"orcid": "https://orcid.org/0009-0001-3517-9245"
},
"institutions": [
{
"id": "https://openalex.org/I1320320070",
"display_name": "United States Food and Drug Administration",
"ror": "https://ror.org/034xvzb47",
"country_code": "US",
"type": "government",
"lineage": [
"https://openalex.org/I1299022934",
"https://openalex.org/I1320320070"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Ravinder Reddy",
"raw_affiliation_strings": [
"Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Division of Food Processing Science and Technology, U.S. Food and Drug Administration, Bedford Park, IL, USA",
"institution_ids": [
"https://openalex.org/I1320320070"
]
}
]
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5069067893",
"display_name": "Renate Reimschuessel",
"orcid": "https://orcid.org/0000-0002-3979-8617"
},
"institutions": [],
"countries": [
"US"
],
"is_corresponding": true,
"raw_author_name": "Renate Reimschuessel",
"raw_affiliation_strings": [
"Cheverly, MD, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Cheverly, MD, USA",
"institution_ids": []
}
]
}
],
"best_oa_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.1177/10406387211029913",
"pdf_url": "https://journals.sagepub.com/doi/pdf/10.1177/10406387211029913",
"source": {
"id": "https://openalex.org/S206734468",
"display_name": "Journal of Veterinary Diagnostic Investigation",
"issn_l": "1040-6387",
"issn": [
"1040-6387",
"1943-4936"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320017",
"host_organization_name": "SAGE Publishing",
"host_organization_lineage": [
"https://openalex.org/P4310320017"
],
"host_organization_lineage_names": [
"SAGE Publishing"
],
"type": "journal"
},
"license": "cc-by-nc",
"license_id": "https://openalex.org/licenses/cc-by-nc",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"biblio": {
"volume": "33",
"issue": "6",
"first_page": "1039",
"last_page": "1051"
},
"citation_normalized_percentile": {
"value": 0.601865,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W3185981165",
"cited_by_count": 9,
"cited_by_percentile_year": {
"min": 87,
"max": 89
},
"concepts": [
{
"id": "https://openalex.org/C9893847",
"wikidata": "https://www.wikidata.org/wiki/Q1425625",
"display_name": "Reproducibility",
"level": 2,
"score": 0.5567192
},
{
"id": "https://openalex.org/C112190416",
"wikidata": "https://www.wikidata.org/wiki/Q2124450",
"display_name": "RNA extraction",
"level": 4,
"score": 0.5339794
},
{
"id": "https://openalex.org/C3007834351",
"wikidata": "https://www.wikidata.org/wiki/Q82069695",
"display_name": "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)",
"level": 5,
"score": 0.44628307
},
{
"id": "https://openalex.org/C67705224",
"wikidata": "https://www.wikidata.org/wiki/Q11053",
"display_name": "RNA",
"level": 3,
"score": 0.44145054
},
{
"id": "https://openalex.org/C42972112",
"wikidata": "https://www.wikidata.org/wiki/Q170201",
"display_name": "Veterinary medicine",
"level": 1,
"score": 0.43437484
},
{
"id": "https://openalex.org/C82157600",
"wikidata": "https://www.wikidata.org/wiki/Q2671652",
"display_name": "Diagnostic test",
"level": 2,
"score": 0.42074487
},
{
"id": "https://openalex.org/C3008058167",
"wikidata": "https://www.wikidata.org/wiki/Q84263196",
"display_name": "Coronavirus disease 2019 (COVID-19)",
"level": 4,
"score": 0.39125603
},
{
"id": "https://openalex.org/C71924100",
"wikidata": "https://www.wikidata.org/wiki/Q11190",
"display_name": "Medicine",
"level": 0,
"score": 0.36428404
},
{
"id": "https://openalex.org/C86803240",
"wikidata": "https://www.wikidata.org/wiki/Q420",
"display_name": "Biology",
"level": 0,
"score": 0.311055
},
{
"id": "https://openalex.org/C43617362",
"wikidata": "https://www.wikidata.org/wiki/Q170050",
"display_name": "Chromatography",
"level": 1,
"score": 0.26691902
},
{
"id": "https://openalex.org/C185592680",
"wikidata": "https://www.wikidata.org/wiki/Q2329",
"display_name": "Chemistry",
"level": 0,
"score": 0.21268156
},
{
"id": "https://openalex.org/C142724271",
"wikidata": "https://www.wikidata.org/wiki/Q7208",
"display_name": "Pathology",
"level": 1,
"score": 0.18189177
},
{
"id": "https://openalex.org/C524204448",
"wikidata": "https://www.wikidata.org/wiki/Q788926",
"display_name": "Infectious disease (medical specialty)",
"level": 3,
"score": 0.1312255
},
{
"id": "https://openalex.org/C2779134260",
"wikidata": "https://www.wikidata.org/wiki/Q12136",
"display_name": "Disease",
"level": 2,
"score": 0.09823406
},
{
"id": "https://openalex.org/C54355233",
"wikidata": "https://www.wikidata.org/wiki/Q7162",
"display_name": "Genetics",
"level": 1,
"score": 0.0918636
},
{
"id": "https://openalex.org/C104317684",
"wikidata": "https://www.wikidata.org/wiki/Q7187",
"display_name": "Gene",
"level": 2,
"score": 0.0
}
],
"corresponding_author_ids": [
"https://openalex.org/A5069067893"
],
"corresponding_institution_ids": [],
"countries_distinct_count": 2,
"counts_by_year": [
{
"year": 2023,
"cited_by_count": 2
},
{
"year": 2022,
"cited_by_count": 7
}
],
"created_date": "2021-08-02",
"datasets": [],
"display_name": "Interlaboratory comparison of SARS-CoV2 molecular detection assays in use by U.S. veterinary diagnostic laboratories",
"doi": "https://doi.org/10.1177/10406387211029913",
"fwci": 0.61,
"grants": [
{
"funder": "https://openalex.org/F4320332163",
"funder_display_name": "U.S. Food and Drug Administration",
"award_id": null
}
],
"has_fulltext": false,
"id": "https://openalex.org/W3185981165",
"ids": {
"openalex": "https://openalex.org/W3185981165",
"doi": "https://doi.org/10.1177/10406387211029913",
"mag": "3185981165",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/34293974",
"pmcid": "https://www.ncbi.nlm.nih.gov/pmc/articles/8532215"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 8,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/saliva-testing",
"display_name": "saliva testing",
"score": 0.509932
}
],
"language": "en",
"locations": [
{
"is_oa": true,
"landing_page_url": "https://doi.org/10.1177/10406387211029913",
"pdf_url": "https://journals.sagepub.com/doi/pdf/10.1177/10406387211029913",
"source": {
"id": "https://openalex.org/S206734468",
"display_name": "Journal of Veterinary Diagnostic Investigation",
"issn_l": "1040-6387",
"issn": [
"1040-6387",
"1943-4936"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320017",
"host_organization_name": "SAGE Publishing",
"host_organization_lineage": [
"https://openalex.org/P4310320017"
],
"host_organization_lineage_names": [
"SAGE Publishing"
],
"type": "journal"
},
"license": "cc-by-nc",
"license_id": "https://openalex.org/licenses/cc-by-nc",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": true,
"landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532215",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S2764455111",
"display_name": "PubMed Central",
"issn_l": null,
"issn": null,
"is_oa": true,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/34293974",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 3,
"mesh": [
{
"descriptor_ui": "D000086382",
"descriptor_name": "COVID-19",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D012367",
"descriptor_name": "RNA, Viral",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D000818",
"descriptor_name": "Animals",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D000086382",
"descriptor_name": "COVID-19",
"qualifier_ui": "Q000662",
"qualifier_name": "veterinary",
"is_major_topic": false
},
{
"descriptor_ui": "D007753",
"descriptor_name": "Laboratories",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D012367",
"descriptor_name": "RNA, Viral",
"qualifier_ui": "Q000235",
"qualifier_name": "genetics",
"is_major_topic": false
},
{
"descriptor_ui": "D015203",
"descriptor_name": "Reproducibility of Results",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D000086402",
"descriptor_name": "SARS-CoV-2",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D012680",
"descriptor_name": "Sensitivity and Specificity",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W3185981165/ngrams",
"open_access": {
"is_oa": true,
"oa_status": "hybrid",
"oa_url": "https://journals.sagepub.com/doi/pdf/10.1177/10406387211029913",
"any_repository_has_fulltext": true
},
"primary_location": {
"is_oa": true,
"landing_page_url": "https://doi.org/10.1177/10406387211029913",
"pdf_url": "https://journals.sagepub.com/doi/pdf/10.1177/10406387211029913",
"source": {
"id": "https://openalex.org/S206734468",
"display_name": "Journal of Veterinary Diagnostic Investigation",
"issn_l": "1040-6387",
"issn": [
"1040-6387",
"1943-4936"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320017",
"host_organization_name": "SAGE Publishing",
"host_organization_lineage": [
"https://openalex.org/P4310320017"
],
"host_organization_lineage_names": [
"SAGE Publishing"
],
"type": "journal"
},
"license": "cc-by-nc",
"license_id": "https://openalex.org/licenses/cc-by-nc",
"version": "publishedVersion",
"is_accepted": true,
"is_published": true
},
"primary_topic": {
"id": "https://openalex.org/T11754",
"display_name": "Diagnostic Methods for COVID-19 Detection",
"score": 0.9999,
"subfield": {
"id": "https://openalex.org/subfields/2725",
"display_name": "Infectious Diseases"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
},
"publication_date": "2021-07-23",
"publication_year": 2021,
"referenced_works": [
"https://openalex.org/W2039816356",
"https://openalex.org/W2045984882",
"https://openalex.org/W2883709330",
"https://openalex.org/W3001195213",
"https://openalex.org/W3009584253",
"https://openalex.org/W3011127849",
"https://openalex.org/W3014233146",
"https://openalex.org/W3015664205",
"https://openalex.org/W3029253266",
"https://openalex.org/W3033825851",
"https://openalex.org/W3033994139",
"https://openalex.org/W3038698073",
"https://openalex.org/W3039540868",
"https://openalex.org/W3039680806",
"https://openalex.org/W3042099287",
"https://openalex.org/W3049208369",
"https://openalex.org/W3081684714",
"https://openalex.org/W3089993778",
"https://openalex.org/W3092197448",
"https://openalex.org/W3102258632"
],
"referenced_works_count": 20,
"related_works": [
"https://openalex.org/W4232242386",
"https://openalex.org/W3196168296",
"https://openalex.org/W3173186018",
"https://openalex.org/W3039857220",
"https://openalex.org/W3007932897",
"https://openalex.org/W2806739216",
"https://openalex.org/W2802891156",
"https://openalex.org/W2384038647",
"https://openalex.org/W2147993839",
"https://openalex.org/W1927445598"
],
"sustainable_development_goals": [
{
"score": 0.6,
"display_name": "Partnerships for the goals",
"id": "https://metadata.un.org/sdg/17"
}
],
"title": "Interlaboratory comparison of SARS-CoV2 molecular detection assays in use by U.S. veterinary diagnostic laboratories",
"topics": [
{
"id": "https://openalex.org/T11754",
"display_name": "Diagnostic Methods for COVID-19 Detection",
"score": 0.9999,
"subfield": {
"id": "https://openalex.org/subfields/2725",
"display_name": "Infectious Diseases"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
},
{
"id": "https://openalex.org/T10118",
"display_name": "Coronavirus Disease 2019 Research",
"score": 0.9998,
"subfield": {
"id": "https://openalex.org/subfields/2725",
"display_name": "Infectious Diseases"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
},
{
"id": "https://openalex.org/T10976",
"display_name": "Gastrointestinal Viral Infections and Vaccines Development",
"score": 0.9996,
"subfield": {
"id": "https://openalex.org/subfields/2725",
"display_name": "Infectious Diseases"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-12T16:24:14.824265",
"versions": []
}
}
