Item talk:Q231449
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{
"USGS Publications Warehouse": { "@context": "https://schema.org", "@type": "Article", "additionalType": "Journal Article", "name": "Evidence for growth hormone/insulin-like growth factor I axis regulation of seawater acclimation in the euryhaline teleost Fundulus heteroclitus", "identifier": [ { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse IndexID", "value": "70020857", "url": "https://pubs.usgs.gov/publication/70020857" }, { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse Internal ID", "value": 70020857 }, { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1006/gcen.1998.7086", "url": "https://doi.org/10.1006/gcen.1998.7086" }, { "@type": "PropertyValue", "propertyID": "ISSN", "value": "00166480" } ], "journal": { "@type": "Periodical", "name": "General and Comparative Endocrinology", "volumeNumber": "111", "issueNumber": "2" }, "inLanguage": "en", "isPartOf": [ { "@type": "CreativeWorkSeries", "name": "General and Comparative Endocrinology" } ], "datePublished": "1998", "dateModified": "2012-03-12", "abstract": "The ability of ovine growth hormone (oGH), recombinant bovine insulin- like growth factor I (rbIGF-I), recombinant human insulin-like growth factor II (rhIGF-II), and bovine insulin to increase hypoosmoregulatory capacity in the euryhaline teleost Fundulus heteroclitus was examined. Fish acclimated to brackish water (BW, 10 ppt salinity, 320 mOsm/kg H2O) were injected with a single dose of hormone and transferred to seawater (SW, 35 ppt salinity, 1120 mOsm/kg H2O) 2 days later. Fish were sampled 24 h after transfer and plasma osmolality, plasma glucose, and gill Na+,K+-ATPase activity were examined. Transfer from BW to SW increased plasma osmolality and gill Na+,K+-ATPase activity. Transfer from BW to BW had no effect on these parameters. rbIGF-I (0.05, 0.1, and 0.2 ??g/g) improved the ability to maintain plasma osmolality and to increase gill Na+, K+-ATPase activity in a dose-dependent manner. oGH (0.5, 1, and 2 ??g/g) also increased hypoosmoregulatory ability but only the higher doses (2 ??g/g) significantly increased gill Na+,K+-ATPase activity. oGH (1 ??g/g) and rbIGF-I (0.1 ??g/g) had a significantly greater effect on plasma osmolality and gill Na+,K+-ATPase activity than either hormone alone. rhIGF-II (0.05, 0.1, and 0.2 ??g/g) and bovine insulin (0.01 and 0.05 ??g/g) were without effect. The results suggest a role of GH and insulin-like growth factor I (IGF-I) in seawater acclimation of E heteroclitus. Based on these findings and previous studies, it is concluded that the capacity of the GH/IGF-I axis to increase hypoosmoregulatory ability may be a common feature of euryhalinity in teleosts.", "publisher": { "@type": "Organization", "name": "U.S. Geological Survey" }, "author": [ { "@type": "Person", "name": "Mancera, J. M.", "givenName": "J. M.", "familyName": "Mancera" }, { "@type": "Person", "name": "McCormick, S. D.", "givenName": "S. 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