Item talk:Q245569

From geokb
Revision as of 20:03, 20 August 2024 by Sky (talk | contribs) (Created page with "{ "USGS Publications Warehouse": { "@context": "https://schema.org", "@type": "Article", "additionalType": "Journal Article", "name": "Prevalent flucocorticoid and androgen activity in US water sources", "identifier": [ { "@type": "PropertyValue", "propertyID": "USGS Publications Warehouse IndexID", "value": "70043599", "url": "https://pubs.usgs.gov/publication/70043599" }, { "@type": "Proper...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

{

 "USGS Publications Warehouse": {
   "@context": "https://schema.org",
   "@type": "Article",
   "additionalType": "Journal Article",
   "name": "Prevalent flucocorticoid and androgen activity in US water sources",
   "identifier": [
     {
       "@type": "PropertyValue",
       "propertyID": "USGS Publications Warehouse IndexID",
       "value": "70043599",
       "url": "https://pubs.usgs.gov/publication/70043599"
     },
     {
       "@type": "PropertyValue",
       "propertyID": "USGS Publications Warehouse Internal ID",
       "value": 70043599
     },
     {
       "@type": "PropertyValue",
       "propertyID": "DOI",
       "value": "10.1038/srep00937",
       "url": "https://doi.org/10.1038/srep00937"
     }
   ],
   "journal": {
     "@type": "Periodical",
     "name": "Scientific Reports",
     "volumeNumber": "2",
     "issueNumber": "937"
   },
   "inLanguage": "en",
   "isPartOf": [
     {
       "@type": "CreativeWorkSeries",
       "name": "Scientific Reports"
     }
   ],
   "datePublished": "2012",
   "dateModified": "2013-07-22",
   "abstract": "Contamination of the environment with endocrine disrupting chemicals (EDCs) is a major health concern. The presence of estrogenic compounds in water and their deleterious effect are well documented. However, detection and monitoring of other classes of EDCs is limited. Here we utilize a high-throughput live cell assay based on sub-cellular relocalization of GFP-tagged glucocorticoid and androgen receptors (GFP-GR and GFP-AR), in combination with gene transcription analysis, to screen for glucocorticoid and androgen activity in water samples. We report previously unrecognized glucocorticoid activity in 27%, and androgen activity in 35% of tested water sources from 14 states in the US. Steroids of both classes impact body development, metabolism, and interfere with reproductive, endocrine, and immune systems. This prevalent contamination could negatively affect wildlife and human populations.",
   "description": "8 p.",
   "publisher": {
     "@type": "Organization",
     "name": "U.S. Geological Survey"
   },
   "author": [
     {
       "@type": "Person",
       "name": "Blazer, Vicki vblazer@usgs.gov",
       "givenName": "Vicki",
       "familyName": "Blazer",
       "email": "vblazer@usgs.gov",
       "identifier": {
         "@type": "PropertyValue",
         "propertyID": "ORCID",
         "value": "0000-0001-6647-9614",
         "url": "https://orcid.org/0000-0001-6647-9614"
       },
       "affiliation": [
         {
           "@type": "Organization",
           "name": "Leetown Science Center",
           "url": "https://www.usgs.gov/centers/eesc"
         }
       ]
     },
     {
       "@type": "Person",
       "name": "Voss, Ty C.",
       "givenName": "Ty C.",
       "familyName": "Voss"
     },
     {
       "@type": "Person",
       "name": "Sack, Daniel",
       "givenName": "Daniel",
       "familyName": "Sack"
     },
     {
       "@type": "Person",
       "name": "Schiltz, R. Louis",
       "givenName": "R. Louis",
       "familyName": "Schiltz"
     },
     {
       "@type": "Person",
       "name": "Hager, Gordon L.",
       "givenName": "Gordon L.",
       "familyName": "Hager"
     },
     {
       "@type": "Person",
       "name": "Stavreva, Diana A.",
       "givenName": "Diana A.",
       "familyName": "Stavreva"
     },
     {
       "@type": "Person",
       "name": "Varticovski, Lyuba",
       "givenName": "Lyuba",
       "familyName": "Varticovski"
     },
     {
       "@type": "Person",
       "name": "Iwanowicz, Luke R.",
       "givenName": "Luke R.",
       "familyName": "Iwanowicz",
       "identifier": {
         "@type": "PropertyValue",
         "propertyID": "ORCID",
         "value": "0000-0002-1197-6178",
         "url": "https://orcid.org/0000-0002-1197-6178"
       },
       "affiliation": [
         {
           "@type": "Organization",
           "name": "Leetown Science Center",
           "url": "https://www.usgs.gov/centers/eesc"
         }
       ]
     },
     {
       "@type": "Person",
       "name": "George, Anuja A.",
       "givenName": "Anuja A.",
       "familyName": "George"
     },
     {
       "@type": "Person",
       "name": "Klausmeyer, Paul",
       "givenName": "Paul",
       "familyName": "Klausmeyer"
     }
   ],
   "funder": [
     {
       "@type": "Organization",
       "name": "Leetown Science Center",
       "url": "https://www.usgs.gov/centers/eesc"
     }
   ],
   "spatialCoverage": [
     {
       "@type": "Place",
       "additionalType": "country",
       "name": "United States",
       "url": "https://geonames.org/4074035"
     },
     {
       "@type": "Place",
       "geo": [
         {
           "@type": "GeoShape",
           "additionalProperty": {
             "@type": "PropertyValue",
             "name": "GeoJSON",
             "value": {
               "type": "FeatureCollection",
               "features": [
                 {
                   "type": "Feature",
                   "properties": {},
                   "geometry": {
                     "type": "Polygon",
                     "coordinates": [
                       [
                         [
                           173.0,
                           16.916667
                         ],
                         [
                           173.0,
                           71.833333
                         ],
                         [
                           -66.95,
                           71.833333
                         ],
                         [
                           -66.95,
                           16.916667
                         ],
                         [
                           173.0,
                           16.916667
                         ]
                       ]
                     ]
                   }
                 }
               ]
             }
           }
         },
         {
           "@type": "GeoCoordinates",
           "latitude": 44.37499999999999,
           "longitude": 53.025
         }
       ]
     }
   ]
 },
 "OpenAlex": {
   "abstract_inverted_index": {
     "Abstract": [
       0
     ],
     "Contamination": [
       1
     ],
     "of": [
       2,
       17,
       33,
       36,
       52,
       90,
       101
     ],
     "the": [
       3,
       98
     ],
     "environment": [
       4
     ],
     "with": [
       5,
       63,
       110
     ],
     "endocrine": [
       6,
       112
     ],
     "disrupting": [
       7
     ],
     "chemicals": [
       8
     ],
     "(EDCs)": [
       9
     ],
     "is": [
       10,
       38
     ],
     "a": [
       11,
       43
     ],
     "major": [
       12
     ],
     "health": [
       13
     ],
     "concern.": [
       14
     ],
     "The": [
       15
     ],
     "presence": [
       16
     ],
     "estrogenic": [
       18
     ],
     "compounds": [
       19
     ],
     "in": [
       20,
       61,
       74,
       83,
       88,
       97
     ],
     "water": [
       21,
       75,
       92
     ],
     "and": [
       22,
       31,
       55,
       59,
       71,
       85,
       108,
       113,
       123
     ],
     "their": [
       23
     ],
     "deleterious": [
       24
     ],
     "effect": [
       25
     ],
     "are": [
       26
     ],
     "well": [
       27
     ],
     "documented.": [
       28
     ],
     "However,": [
       29
     ],
     "detection": [
       30
     ],
     "monitoring": [
       32
     ],
     "other": [
       34
     ],
     "classes": [
       35,
       103
     ],
     "EDCs": [
       37
     ],
     "limited.": [
       39
     ],
     "Here": [
       40
     ],
     "we": [
       41
     ],
     "utilize": [
       42
     ],
     "high-throughput": [
       44
     ],
     "live": [
       45
     ],
     "cell": [
       46
     ],
     "assay": [
       47
     ],
     "based": [
       48
     ],
     "on": [
       49
     ],
     "sub-cellular": [
       50
     ],
     "relocalization": [
       51
     ],
     "GFP-tagged": [
       53
     ],
     "glucocorticoid": [
       54,
       70,
       81
     ],
     "androgen": [
       56,
       72,
       86
     ],
     "receptors": [
       57
     ],
     "(GFP-GR": [
       58
     ],
     "GFP-AR),": [
       60
     ],
     "combination": [
       62
     ],
     "gene": [
       64
     ],
     "transcription": [
       65
     ],
     "analysis,": [
       66
     ],
     "to": [
       67
     ],
     "screen": [
       68
     ],
     "for": [
       69
     ],
     "activity": [
       73,
       82,
       87
     ],
     "samples.": [
       76
     ],
     "We": [
       77
     ],
     "report": [
       78
     ],
     "previously": [
       79
     ],
     "unrecognized": [
       80
     ],
     "27%": [
       84
     ],
     "35%": [
       89
     ],
     "tested": [
       91
     ],
     "sources": [
       93
     ],
     "from": [
       94
     ],
     "14": [
       95
     ],
     "states": [
       96
     ],
     "US.": [
       99
     ],
     "Steroids": [
       100
     ],
     "both": [
       102
     ],
     "impact": [
       104
     ],
     "body": [
       105
     ],
     "development,": [
       106
     ],
     "metabolism": [
       107
     ],
     "interfere": [
       109
     ],
     "reproductive,": [
       111
     ],
     "immune": [
       114
     ],
     "systems.": [
       115
     ],
     "This": [
       116
     ],
     "prevalent": [
       117
     ],
     "contamination": [
       118
     ],
     "could": [
       119
     ],
     "negatively": [
       120
     ],
     "affect": [
       121
     ],
     "wildlife": [
       122
     ],
     "human": [
       124
     ],
     "populations.": [
       125
     ]
   },
   "apc_list": {
     "value": 1890,
     "currency": "EUR",
     "value_usd": 2190,
     "provenance": "doaj"
   },
   "apc_paid": {
     "value": 1890,
     "currency": "EUR",
     "value_usd": 2190,
     "provenance": "doaj"
   },
   "authorships": [
     {
       "author_position": "first",
       "author": {
         "id": "https://openalex.org/A5068571537",
         "display_name": "Diana A. Stavreva",
         "orcid": "https://orcid.org/0000-0002-7904-6452"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Diana A. Stavreva",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5064165819",
         "display_name": "Anuja A. George",
         "orcid": "https://orcid.org/0000-0003-2643-6307"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Anuja A. George",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5054008918",
         "display_name": "Paul Klausmeyer",
         "orcid": null
       },
       "institutions": [
         {
           "id": "https://openalex.org/I880747138",
           "display_name": "Science Applications International Corporation (United States)",
           "ror": "https://ror.org/00zv91802",
           "country_code": "US",
           "type": "company",
           "lineage": [
             "https://openalex.org/I880747138"
           ]
         },
         {
           "id": "https://openalex.org/I4210130649",
           "display_name": "Frederick National Laboratory for Cancer Research",
           "ror": "https://ror.org/03v6m3209",
           "country_code": "US",
           "type": "facility",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210130649",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Paul Klausmeyer",
       "raw_affiliation_strings": [
         "Natural Products Support Group SAIC-Frederick, Inc Frederick National Laboratory for Cancer Research Frederick, MD 21702"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Natural Products Support Group SAIC-Frederick, Inc Frederick National Laboratory for Cancer Research Frederick, MD 21702",
           "institution_ids": [
             "https://openalex.org/I880747138",
             "https://openalex.org/I4210130649"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5045616664",
         "display_name": "Lyuba Varticovski",
         "orcid": "https://orcid.org/0000-0002-5105-9008"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Lyuba Varticovski",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5045753436",
         "display_name": "Daniel Sack",
         "orcid": "https://orcid.org/0000-0003-0864-8875"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Daniel Sack",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5061531680",
         "display_name": "Ty C. Voss",
         "orcid": "https://orcid.org/0009-0002-8750-2478"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Ty C. Voss",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5054066176",
         "display_name": "R. Louis Schiltz",
         "orcid": "https://orcid.org/0000-0002-7314-3753"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "R. Louis Schiltz",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5004985533",
         "display_name": "Vicki S. Blazer",
         "orcid": "https://orcid.org/0000-0001-6647-9614"
       },
       "institutions": [],
       "countries": [],
       "is_corresponding": false,
       "raw_author_name": "Vicki S. Blazer",
       "raw_affiliation_strings": [
         "USGS-BRD Leetown Science Center 11649 Leetown Road Kearneysville, WV 25430"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "USGS-BRD Leetown Science Center 11649 Leetown Road Kearneysville, WV 25430",
           "institution_ids": []
         }
       ]
     },
     {
       "author_position": "middle",
       "author": {
         "id": "https://openalex.org/A5012293449",
         "display_name": "Luke R. Iwanowicz",
         "orcid": "https://orcid.org/0000-0002-1197-6178"
       },
       "institutions": [],
       "countries": [],
       "is_corresponding": false,
       "raw_author_name": "Luke R. Iwanowicz",
       "raw_affiliation_strings": [
         "USGS-BRD Leetown Science Center 11649 Leetown Road Kearneysville, WV 25430"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "USGS-BRD Leetown Science Center 11649 Leetown Road Kearneysville, WV 25430",
           "institution_ids": []
         }
       ]
     },
     {
       "author_position": "last",
       "author": {
         "id": "https://openalex.org/A5023528108",
         "display_name": "Gordon L. Hager",
         "orcid": "https://orcid.org/0000-0002-9300-5331"
       },
       "institutions": [
         {
           "id": "https://openalex.org/I4210140884",
           "display_name": "National Cancer Institute",
           "ror": "https://ror.org/040gcmg81",
           "country_code": "US",
           "type": "government",
           "lineage": [
             "https://openalex.org/I1299022934",
             "https://openalex.org/I1299303238",
             "https://openalex.org/I4210140884"
           ]
         }
       ],
       "countries": [
         "US"
       ],
       "is_corresponding": false,
       "raw_author_name": "Gordon L. Hager",
       "raw_affiliation_strings": [
         "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055"
       ],
       "affiliations": [
         {
           "raw_affiliation_string": "Laboratory of Receptor Biology and Gene Expression Building 41, B602 41 Library Dr. National Cancer Institute, NIH, Bethesda, MD 20892-5055",
           "institution_ids": [
             "https://openalex.org/I4210140884"
           ]
         }
       ]
     }
   ],
   "best_oa_location": {
     "is_oa": true,
     "landing_page_url": "https://doi.org/10.1038/srep00937",
     "pdf_url": "https://www.nature.com/articles/srep00937.pdf",
     "source": {
       "id": "https://openalex.org/S196734849",
       "display_name": "Scientific Reports",
       "issn_l": "2045-2322",
       "issn": [
         "2045-2322"
       ],
       "is_oa": true,
       "is_in_doaj": true,
       "is_core": true,
       "host_organization": "https://openalex.org/P4310319908",
       "host_organization_name": "Nature Portfolio",
       "host_organization_lineage": [
         "https://openalex.org/P4310319908",
         "https://openalex.org/P4310319965"
       ],
       "host_organization_lineage_names": [
         "Nature Portfolio",
         "Springer Nature"
       ],
       "type": "journal"
     },
     "license": "cc-by",
     "license_id": "https://openalex.org/licenses/cc-by",
     "version": "publishedVersion",
     "is_accepted": true,
     "is_published": true
   },
   "biblio": {
     "volume": "2",
     "issue": "1",
     "first_page": null,
     "last_page": null
   },
   "citation_normalized_percentile": {
     "value": 0.898521,
     "is_in_top_1_percent": false,
     "is_in_top_10_percent": false
   },
   "cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2148731562",
   "cited_by_count": 60,
   "cited_by_percentile_year": {
     "min": 96,
     "max": 97
   },
   "concepts": [
     {
       "id": "https://openalex.org/C2780841215",
       "wikidata": "https://www.wikidata.org/wiki/Q422549",
       "display_name": "Glucocorticoid",
       "level": 2,
       "score": 0.81495136
     },
     {
       "id": "https://openalex.org/C2777911890",
       "wikidata": "https://www.wikidata.org/wiki/Q62614",
       "display_name": "Androgen",
       "level": 3,
       "score": 0.7551083
     },
     {
       "id": "https://openalex.org/C59493245",
       "wikidata": "https://www.wikidata.org/wiki/Q14877410",
       "display_name": "Glucocorticoid receptor",
       "level": 3,
       "score": 0.73821944
     },
     {
       "id": "https://openalex.org/C61367390",
       "wikidata": "https://www.wikidata.org/wiki/Q416601",
       "display_name": "Androgen receptor",
       "level": 4,
       "score": 0.6870211
     },
     {
       "id": "https://openalex.org/C2780862370",
       "wikidata": "https://www.wikidata.org/wiki/Q1138899",
       "display_name": "Endocrine disruptor",
       "level": 4,
       "score": 0.6630863
     },
     {
       "id": "https://openalex.org/C46699223",
       "wikidata": "https://www.wikidata.org/wiki/Q11078",
       "display_name": "Endocrine system",
       "level": 3,
       "score": 0.5947855
     },
     {
       "id": "https://openalex.org/C86803240",
       "wikidata": "https://www.wikidata.org/wiki/Q420",
       "display_name": "Biology",
       "level": 0,
       "score": 0.52262336
     },
     {
       "id": "https://openalex.org/C185592680",
       "wikidata": "https://www.wikidata.org/wiki/Q2329",
       "display_name": "Chemistry",
       "level": 0,
       "score": 0.36862275
     },
     {
       "id": "https://openalex.org/C71315377",
       "wikidata": "https://www.wikidata.org/wiki/Q11364",
       "display_name": "Hormone",
       "level": 2,
       "score": 0.33632386
     },
     {
       "id": "https://openalex.org/C134018914",
       "wikidata": "https://www.wikidata.org/wiki/Q162606",
       "display_name": "Endocrinology",
       "level": 1,
       "score": 0.31334737
     },
     {
       "id": "https://openalex.org/C54355233",
       "wikidata": "https://www.wikidata.org/wiki/Q7162",
       "display_name": "Genetics",
       "level": 1,
       "score": 0.08179274
     },
     {
       "id": "https://openalex.org/C2780192828",
       "wikidata": "https://www.wikidata.org/wiki/Q181257",
       "display_name": "Prostate cancer",
       "level": 3,
       "score": 0.0
     },
     {
       "id": "https://openalex.org/C121608353",
       "wikidata": "https://www.wikidata.org/wiki/Q12078",
       "display_name": "Cancer",
       "level": 2,
       "score": 0.0
     }
   ],
   "corresponding_author_ids": [],
   "corresponding_institution_ids": [],
   "countries_distinct_count": 1,
   "counts_by_year": [
     {
       "year": 2024,
       "cited_by_count": 2
     },
     {
       "year": 2023,
       "cited_by_count": 1
     },
     {
       "year": 2022,
       "cited_by_count": 4
     },
     {
       "year": 2021,
       "cited_by_count": 9
     },
     {
       "year": 2020,
       "cited_by_count": 7
     },
     {
       "year": 2019,
       "cited_by_count": 3
     },
     {
       "year": 2018,
       "cited_by_count": 4
     },
     {
       "year": 2017,
       "cited_by_count": 6
     },
     {
       "year": 2016,
       "cited_by_count": 6
     },
     {
       "year": 2015,
       "cited_by_count": 7
     },
     {
       "year": 2014,
       "cited_by_count": 5
     },
     {
       "year": 2013,
       "cited_by_count": 5
     }
   ],
   "created_date": "2016-06-24",
   "datasets": [],
   "display_name": "Prevalent Glucocorticoid and Androgen Activity in US Water Sources",
   "doi": "https://doi.org/10.1038/srep00937",
   "fulltext_origin": "pdf",
   "fwci": 3.188,
   "grants": [],
   "has_fulltext": true,
   "id": "https://openalex.org/W2148731562",
   "ids": {
     "openalex": "https://openalex.org/W2148731562",
     "doi": "https://doi.org/10.1038/srep00937",
     "mag": "2148731562",
     "pmid": "https://pubmed.ncbi.nlm.nih.gov/23226835",
     "pmcid": "https://www.ncbi.nlm.nih.gov/pmc/articles/3515810"
   },
   "indexed_in": [
     "crossref",
     "pubmed"
   ],
   "institutions_distinct_count": 3,
   "is_paratext": false,
   "is_retracted": false,
   "keywords": [
     {
       "id": "https://openalex.org/keywords/endocrine-disruptor",
       "display_name": "Endocrine disruptor",
       "score": 0.6630863
     },
     {
       "id": "https://openalex.org/keywords/endocrine-disrupting-chemicals",
       "display_name": "Endocrine-Disrupting Chemicals",
       "score": 0.54375
     },
     {
       "id": "https://openalex.org/keywords/hormonal-activity",
       "display_name": "Hormonal Activity",
       "score": 0.536622
     }
   ],
   "language": "en",
   "locations": [
     {
       "is_oa": true,
       "landing_page_url": "https://doi.org/10.1038/srep00937",
       "pdf_url": "https://www.nature.com/articles/srep00937.pdf",
       "source": {
         "id": "https://openalex.org/S196734849",
         "display_name": "Scientific Reports",
         "issn_l": "2045-2322",
         "issn": [
           "2045-2322"
         ],
         "is_oa": true,
         "is_in_doaj": true,
         "is_core": true,
         "host_organization": "https://openalex.org/P4310319908",
         "host_organization_name": "Nature Portfolio",
         "host_organization_lineage": [
           "https://openalex.org/P4310319908",
           "https://openalex.org/P4310319965"
         ],
         "host_organization_lineage_names": [
           "Nature Portfolio",
           "Springer Nature"
         ],
         "type": "journal"
       },
       "license": "cc-by",
       "license_id": "https://openalex.org/licenses/cc-by",
       "version": "publishedVersion",
       "is_accepted": true,
       "is_published": true
     },
     {
       "is_oa": true,
       "landing_page_url": "https://europepmc.org/articles/pmc3515810",
       "pdf_url": "https://europepmc.org/articles/pmc3515810?pdf=render",
       "source": {
         "id": "https://openalex.org/S4306400806",
         "display_name": "Europe PMC (PubMed Central)",
         "issn_l": null,
         "issn": null,
         "is_oa": true,
         "is_in_doaj": false,
         "is_core": false,
         "host_organization": "https://openalex.org/I1303153112",
         "host_organization_name": "European Bioinformatics Institute",
         "host_organization_lineage": [
           "https://openalex.org/I1303153112"
         ],
         "host_organization_lineage_names": [
           "European Bioinformatics Institute"
         ],
         "type": "repository"
       },
       "license": "cc-by",
       "license_id": "https://openalex.org/licenses/cc-by",
       "version": "publishedVersion",
       "is_accepted": true,
       "is_published": true
     },
     {
       "is_oa": true,
       "landing_page_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515810",
       "pdf_url": null,
       "source": {
         "id": "https://openalex.org/S2764455111",
         "display_name": "PubMed Central",
         "issn_l": null,
         "issn": null,
         "is_oa": true,
         "is_in_doaj": false,
         "is_core": false,
         "host_organization": "https://openalex.org/I1299303238",
         "host_organization_name": "National Institutes of Health",
         "host_organization_lineage": [
           "https://openalex.org/I1299303238"
         ],
         "host_organization_lineage_names": [
           "National Institutes of Health"
         ],
         "type": "repository"
       },
       "license": null,
       "license_id": null,
       "version": "publishedVersion",
       "is_accepted": true,
       "is_published": true
     },
     {
       "is_oa": false,
       "landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/23226835",
       "pdf_url": null,
       "source": {
         "id": "https://openalex.org/S4306525036",
         "display_name": "PubMed",
         "issn_l": null,
         "issn": null,
         "is_oa": false,
         "is_in_doaj": false,
         "is_core": false,
         "host_organization": "https://openalex.org/I1299303238",
         "host_organization_name": "National Institutes of Health",
         "host_organization_lineage": [
           "https://openalex.org/I1299303238"
         ],
         "host_organization_lineage_names": [
           "National Institutes of Health"
         ],
         "type": "repository"
       },
       "license": null,
       "license_id": null,
       "version": null,
       "is_accepted": false,
       "is_published": false
     }
   ],
   "locations_count": 4,
   "mesh": [
     {
       "descriptor_ui": "D000728",
       "descriptor_name": "Androgens",
       "qualifier_ui": "Q000032",
       "qualifier_name": "analysis",
       "is_major_topic": true
     },
     {
       "descriptor_ui": "D005938",
       "descriptor_name": "Glucocorticoids",
       "qualifier_ui": "Q000032",
       "qualifier_name": "analysis",
       "is_major_topic": true
     },
     {
       "descriptor_ui": "D014874",
       "descriptor_name": "Water Pollutants, Chemical",
       "qualifier_ui": "Q000032",
       "qualifier_name": "analysis",
       "is_major_topic": true
     },
     {
       "descriptor_ui": "D000818",
       "descriptor_name": "Animals",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D001483",
       "descriptor_name": "Base Sequence",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D045744",
       "descriptor_name": "Cell Line, Tumor",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D017931",
       "descriptor_name": "DNA Primers",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D051379",
       "descriptor_name": "Mice",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D016133",
       "descriptor_name": "Polymerase Chain Reaction",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D011944",
       "descriptor_name": "Receptors, Androgen",
       "qualifier_ui": "Q000378",
       "qualifier_name": "metabolism",
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D011965",
       "descriptor_name": "Receptors, Glucocorticoid",
       "qualifier_ui": "Q000378",
       "qualifier_name": "metabolism",
       "is_major_topic": false
     },
     {
       "descriptor_ui": "D014481",
       "descriptor_name": "United States",
       "qualifier_ui": "",
       "qualifier_name": null,
       "is_major_topic": false
     }
   ],
   "ngrams_url": "https://api.openalex.org/works/W2148731562/ngrams",
   "open_access": {
     "is_oa": true,
     "oa_status": "gold",
     "oa_url": "https://www.nature.com/articles/srep00937.pdf",
     "any_repository_has_fulltext": true
   },
   "primary_location": {
     "is_oa": true,
     "landing_page_url": "https://doi.org/10.1038/srep00937",
     "pdf_url": "https://www.nature.com/articles/srep00937.pdf",
     "source": {
       "id": "https://openalex.org/S196734849",
       "display_name": "Scientific Reports",
       "issn_l": "2045-2322",
       "issn": [
         "2045-2322"
       ],
       "is_oa": true,
       "is_in_doaj": true,
       "is_core": true,
       "host_organization": "https://openalex.org/P4310319908",
       "host_organization_name": "Nature Portfolio",
       "host_organization_lineage": [
         "https://openalex.org/P4310319908",
         "https://openalex.org/P4310319965"
       ],
       "host_organization_lineage_names": [
         "Nature Portfolio",
         "Springer Nature"
       ],
       "type": "journal"
     },
     "license": "cc-by",
     "license_id": "https://openalex.org/licenses/cc-by",
     "version": "publishedVersion",
     "is_accepted": true,
     "is_published": true
   },
   "primary_topic": {
     "id": "https://openalex.org/T10686",
     "display_name": "Endocrine Disruption by Chemical Exposure",
     "score": 0.9982,
     "subfield": {
       "id": "https://openalex.org/subfields/2307",
       "display_name": "Health, Toxicology and Mutagenesis"
     },
     "field": {
       "id": "https://openalex.org/fields/23",
       "display_name": "Environmental Science"
     },
     "domain": {
       "id": "https://openalex.org/domains/3",
       "display_name": "Physical Sciences"
     }
   },
   "publication_date": "2012-12-06",
   "publication_year": 2012,
   "referenced_works": [
     "https://openalex.org/W1963841973",
     "https://openalex.org/W1965222604",
     "https://openalex.org/W1965896502",
     "https://openalex.org/W1969072719",
     "https://openalex.org/W1982519328",
     "https://openalex.org/W1995131124",
     "https://openalex.org/W1997103341",
     "https://openalex.org/W1998913944",
     "https://openalex.org/W1998923053",
     "https://openalex.org/W2004181758",
     "https://openalex.org/W2009464885",
     "https://openalex.org/W2010142538",
     "https://openalex.org/W2010360420",
     "https://openalex.org/W2012229822",
     "https://openalex.org/W2016361668",
     "https://openalex.org/W2024033014",
     "https://openalex.org/W2027075319",
     "https://openalex.org/W2028296747",
     "https://openalex.org/W2033678048",
     "https://openalex.org/W2037766564",
     "https://openalex.org/W2051716513",
     "https://openalex.org/W2053268946",
     "https://openalex.org/W2054146939",
     "https://openalex.org/W2060925737",
     "https://openalex.org/W2063299997",
     "https://openalex.org/W2077726145",
     "https://openalex.org/W2078746859",
     "https://openalex.org/W2081516273",
     "https://openalex.org/W2086951855",
     "https://openalex.org/W2097327668",
     "https://openalex.org/W2105260607",
     "https://openalex.org/W2109620914",
     "https://openalex.org/W2117286783",
     "https://openalex.org/W2121128732",
     "https://openalex.org/W2124012649",
     "https://openalex.org/W2139826516",
     "https://openalex.org/W2165700542",
     "https://openalex.org/W2166095387",
     "https://openalex.org/W2167003222",
     "https://openalex.org/W2171453169",
     "https://openalex.org/W2327251869",
     "https://openalex.org/W2414746107",
     "https://openalex.org/W297083069",
     "https://openalex.org/W4210478665"
   ],
   "referenced_works_count": 44,
   "related_works": [
     "https://openalex.org/W4318460051",
     "https://openalex.org/W269771094",
     "https://openalex.org/W2436275868",
     "https://openalex.org/W2359066614",
     "https://openalex.org/W2338237228",
     "https://openalex.org/W2169608764",
     "https://openalex.org/W2119824100",
     "https://openalex.org/W2070579680",
     "https://openalex.org/W1981540681",
     "https://openalex.org/W1578882671"
   ],
   "sustainable_development_goals": [
     {
       "score": 0.86,
       "display_name": "Clean water and sanitation",
       "id": "https://metadata.un.org/sdg/6"
     }
   ],
   "title": "Prevalent Glucocorticoid and Androgen Activity in US Water Sources",
   "topics": [
     {
       "id": "https://openalex.org/T10686",
       "display_name": "Endocrine Disruption by Chemical Exposure",
       "score": 0.9982,
       "subfield": {
         "id": "https://openalex.org/subfields/2307",
         "display_name": "Health, Toxicology and Mutagenesis"
       },
       "field": {
         "id": "https://openalex.org/fields/23",
         "display_name": "Environmental Science"
       },
       "domain": {
         "id": "https://openalex.org/domains/3",
         "display_name": "Physical Sciences"
       }
     },
     {
       "id": "https://openalex.org/T10419",
       "display_name": "Antibiotic Resistance in Aquatic Environments and Wastewater",
       "score": 0.9744,
       "subfield": {
         "id": "https://openalex.org/subfields/2310",
         "display_name": "Pollution"
       },
       "field": {
         "id": "https://openalex.org/fields/23",
         "display_name": "Environmental Science"
       },
       "domain": {
         "id": "https://openalex.org/domains/3",
         "display_name": "Physical Sciences"
       }
     },
     {
       "id": "https://openalex.org/T11869",
       "display_name": "Perfluoroalkyl and Polyfluoroalkyl Substances in the Environment",
       "score": 0.9095,
       "subfield": {
         "id": "https://openalex.org/subfields/2304",
         "display_name": "Environmental Chemistry"
       },
       "field": {
         "id": "https://openalex.org/fields/23",
         "display_name": "Environmental Science"
       },
       "domain": {
         "id": "https://openalex.org/domains/3",
         "display_name": "Physical Sciences"
       }
     }
   ],
   "type": "article",
   "type_crossref": "journal-article",
   "updated_date": "2024-08-15T13:19:17.238726",
   "versions": []
 }

}