Item talk:Q269641
From geokb
{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Kangaroo rat bone compared to white rat bone after short-term disuse and exercise",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70174770",
"url": "https://pubs.usgs.gov/publication/70174770"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70174770
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/0300-9629(96)00025-4",
"url": "https://doi.org/10.1016/0300-9629(96)00025-4"
}
],
"journal": {
"@type": "Periodical",
"name": "Comparative Biochemistry and Physiology, Part A: Physiology",
"volumeNumber": "114",
"issueNumber": "4"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Comparative Biochemistry and Physiology, Part A: Physiology"
}
],
"datePublished": "1996",
"dateModified": "2017-05-05",
"abstract": "Kangaroo rats (Dipodomys ordii) were used to study the effects of confinement on mechanical properties of bone with a long range objective of proposing an alternative to the white rat model for the study of disuse osteoporosis. Kangaroo rats exhibit bipedal locomotion, which subjects their limbs to substantial accelerative forces in addition to the normal stress of weight bearing. We subjected groups of kangaroo rats and white rats (Rattus norvegicus) to one of two confinement treatments or to an exercise regime; animals were exercised at a rate calculated to replicate their (respective) daily exercise patterns. White laboratory rats were used as the comparison because they are currently the accepted model used in the study of disuse osteoporosis. After 6 weeks of treatment, rats were killed and the long bones of their hind limbs were tested mechanically and examined for histomorphometric changes. We found that kangaroo rats held in confinement had less ash content in their hind limbs than exercised kangaroo rats. In general, treated kangaroo rats showed morphometric and mechanical bone deterioration compared to controls and exercised kangaroo rats appeared to have slightly \u201cstronger\u201d bones than confined animals. White rats exhibited no significant differences between treatments. These preliminary results suggest that kangaroo rats may be an effective model in the study of disuse osteoporosis.",
"description": "7 p.",
"publisher": {
"@type": "Organization",
"name": "Elsevier"
},
"author": [
{
"@type": "Person",
"name": "Muths, E.",
"givenName": "E.",
"familyName": "Muths"
},
{
"@type": "Person",
"name": "Reichman, O. J.",
"givenName": "O. J.",
"familyName": "Reichman"
}
],
"funder": [
{
"@type": "Organization",
"name": "Fort Collins Science Center",
"url": "https://www.usgs.gov/centers/fort-collins-science-center"
}
]
},
"OpenAlex": {
"_id": "https://openalex.org/w2095173856",
"abstract_inverted_index": {
"Kangaroo": [
0,
37
],
"rats": [
1,
38,
64,
67,
97,
122,
145,
165,
178,
189,
202
],
"(Dipodomys": [
2
],
"ordii)": [
3
],
"were": [
4,
82,
98,
123,
133
],
"used": [
5,
99,
110
],
"to": [
6,
26,
46,
52,
70,
77,
88,
173,
180
],
"study": [
7,
33,
113,
210
],
"the": [
8,
27,
32,
53,
101,
107,
112,
126,
209
],
"effects": [
9
],
"of": [
10,
15,
22,
34,
56,
62,
72,
114,
120,
129,
211
],
"confinement": [
11,
74,
148
],
"on": [
12
],
"mechanical": [
13,
169
],
"properties": [
14
],
"bone": [
16,
170
],
"with": [
17
],
"a": [
18,
85
],
"long": [
19,
127
],
"range": [
20
],
"objective": [
21
],
"proposing": [
23
],
"an": [
24,
78,
205
],
"alternative": [
25
],
"white": [
28,
66
],
"rat": [
29
],
"model": [
30,
109,
207
],
"for": [
31,
138
],
"disuse": [
35,
115,
212
],
"osteoporosis.": [
36,
116,
213
],
"exhibit": [
39
],
"bipedal": [
40
],
"locomotion,": [
41
],
"which": [
42
],
"subjects": [
43
],
"their": [
44,
90,
130,
154
],
"limbs": [
45,
132,
156
],
"substantial": [
47
],
"accelerative": [
48
],
"forces": [
49
],
"in": [
50,
111,
147,
153,
208
],
"addition": [
51
],
"normal": [
54
],
"stress": [
55
],
"weight": [
57
],
"bearing.": [
58
],
"We": [
59,
141
],
"subjected": [
60
],
"groups": [
61
],
"kangaroo": [
63,
144,
159,
164,
177,
201
],
"and": [
65,
125,
136,
168,
175
],
"(Rattus": [
68
],
"norvegicus)": [
69
],
"one": [
71
],
"two": [
73
],
"treatments": [
75
],
"or": [
76
],
"exercise": [
79,
93
],
"regime;": [
80
],
"animals": [
81
],
"exercised": [
83,
158,
176
],
"at": [
84
],
"rate": [
86
],
"calculated": [
87
],
"replicate": [
89
],
"(respective)": [
91
],
"daily": [
92
],
"patterns.": [
94
],
"White": [
95,
188
],
"laboratory": [
96
],
"as": [
100
],
"comparison": [
102
],
"because": [
103
],
"they": [
104
],
"are": [
105
],
"currently": [
106
],
"accepted": [
108
],
"After": [
117
],
"6": [
118
],
"weeks": [
119
],
"treatment,": [
121
],
"killed": [
124
],
"bones": [
128,
184
],
"hind": [
131,
155
],
"tested": [
134
],
"mechanically": [
135
],
"examined": [
137
],
"histomorphometric": [
139
],
"changes.": [
140
],
"found": [
142
],
"that": [
143,
200
],
"held": [
146
],
"had": [
149
],
"less": [
150
],
"ash": [
151
],
"content": [
152
],
"than": [
157,
185
],
"rats.": [
160
],
"In": [
161
],
"general,": [
162
],
"treated": [
163
],
"showed": [
166
],
"morphometric": [
167
],
"deterioration": [
171
],
"compared": [
172
],
"controls": [
174
],
"appeared": [
179
],
"have": [
181
],
"slightly": [
182
],
"\u201cstronger\u201d": [
183
],
"confined": [
186
],
"animals.": [
187
],
"exhibited": [
190
],
"no": [
191
],
"significant": [
192
],
"differences": [
193
],
"between": [
194
],
"treatments.": [
195
],
"These": [
196
],
"preliminary": [
197
],
"results": [
198
],
"suggest": [
199
],
"may": [
203
],
"be": [
204
],
"effective": [
206
]
},
"apc_list": null,
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5083978377",
"display_name": "Erin Muths",
"orcid": "https://orcid.org/0000-0002-5498-3132"
},
"institutions": [],
"countries": [
"US"
],
"is_corresponding": true,
"raw_author_name": "E. Muths",
"raw_affiliation_strings": [
"National Biological Service, Midcontinent Ecological Science Center, Vertebrate Ecology Section, 4512 McMurry Ave, Fort Collins, CO 80525, USA"
],
"affiliations": [
{
"raw_affiliation_string": "National Biological Service, Midcontinent Ecological Science Center, Vertebrate Ecology Section, 4512 McMurry Ave, Fort Collins, CO 80525, USA",
"institution_ids": []
}
]
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5066117353",
"display_name": "O. J. Reichman",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I189590672",
"display_name": "Kansas State University",
"ror": "https://ror.org/05p1j8758",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I189590672"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "O.J. Reichman",
"raw_affiliation_strings": [
"Division of Biology, Kansas State University, Manhattan, KS 66506, USA"
],
"affiliations": [
{
"raw_affiliation_string": "Division of Biology, Kansas State University, Manhattan, KS 66506, USA",
"institution_ids": [
"https://openalex.org/I189590672"
]
}
]
}
],
"best_oa_location": null,
"biblio": {
"volume": "114",
"issue": "4",
"first_page": "355",
"last_page": "361"
},
"citation_normalized_percentile": {
"value": 0.569477,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2095173856",
"cited_by_count": 6,
"cited_by_percentile_year": {
"min": 73,
"max": 75
},
"concepts": [
{
"id": "https://openalex.org/C2776541429",
"wikidata": "https://www.wikidata.org/wiki/Q165328",
"display_name": "Osteoporosis",
"level": 2,
"score": 0.5086575
},
{
"id": "https://openalex.org/C71924100",
"wikidata": "https://www.wikidata.org/wiki/Q11190",
"display_name": "Medicine",
"level": 0,
"score": 0.4904968
},
{
"id": "https://openalex.org/C51738704",
"wikidata": "https://www.wikidata.org/wiki/Q5766112",
"display_name": "Hindlimb",
"level": 2,
"score": 0.46271062
},
{
"id": "https://openalex.org/C3019114686",
"wikidata": "https://www.wikidata.org/wiki/Q3089676",
"display_name": "Rat model",
"level": 2,
"score": 0.4302785
},
{
"id": "https://openalex.org/C105702510",
"wikidata": "https://www.wikidata.org/wiki/Q514",
"display_name": "Anatomy",
"level": 1,
"score": 0.4169237
},
{
"id": "https://openalex.org/C86803240",
"wikidata": "https://www.wikidata.org/wiki/Q420",
"display_name": "Biology",
"level": 0,
"score": 0.38589704
},
{
"id": "https://openalex.org/C126322002",
"wikidata": "https://www.wikidata.org/wiki/Q11180",
"display_name": "Internal medicine",
"level": 1,
"score": 0.31521374
}
],
"corresponding_author_ids": [
"https://openalex.org/A5083978377"
],
"corresponding_institution_ids": [],
"countries_distinct_count": 1,
"counts_by_year": [
{
"year": 2016,
"cited_by_count": 1
},
{
"year": 2015,
"cited_by_count": 1
},
{
"year": 2012,
"cited_by_count": 1
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Kangaroo rat bone compared to white rat bone after short-term disuse and exercise",
"doi": "https://doi.org/10.1016/0300-9629(96)00025-4",
"fulltext_origin": "ngrams",
"fwci": 0.0,
"grants": [],
"has_fulltext": true,
"id": "https://openalex.org/W2095173856",
"ids": {
"openalex": "https://openalex.org/W2095173856",
"doi": "https://doi.org/10.1016/0300-9629(96)00025-4",
"mag": "2095173856",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/8759284"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 1,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/limb-function",
"display_name": "Limb Function",
"score": 0.468613
},
{
"id": "https://openalex.org/keywords/hindlimb",
"display_name": "Hindlimb",
"score": 0.46271062
},
{
"id": "https://openalex.org/keywords/rat-model",
"display_name": "Rat model",
"score": 0.4302785
}
],
"language": "en",
"locations": [
{
"is_oa": false,
"landing_page_url": "https://doi.org/10.1016/0300-9629(96)00025-4",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S126806126",
"display_name": "Comparative Biochemistry and Physiology Part A Physiology",
"issn_l": "0300-9629",
"issn": [
"0300-9629"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/P4310320990",
"host_organization_name": "Elsevier BV",
"host_organization_lineage": [
"https://openalex.org/P4310320990"
],
"host_organization_lineage_names": [
"Elsevier BV"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/8759284",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 2,
"mesh": [
{
"descriptor_ui": "D001842",
"descriptor_name": "Bone and Bones",
"qualifier_ui": "Q000502",
"qualifier_name": "physiology",
"is_major_topic": true
},
{
"descriptor_ui": "D007103",
"descriptor_name": "Immobilization",
"qualifier_ui": "Q000502",
"qualifier_name": "physiology",
"is_major_topic": true
},
{
"descriptor_ui": "D010024",
"descriptor_name": "Osteoporosis",
"qualifier_ui": "Q000209",
"qualifier_name": "etiology",
"is_major_topic": true
},
{
"descriptor_ui": "D010805",
"descriptor_name": "Physical Conditioning, Animal",
"qualifier_ui": "Q000502",
"qualifier_name": "physiology",
"is_major_topic": true
},
{
"descriptor_ui": "D000818",
"descriptor_name": "Animals",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D001842",
"descriptor_name": "Bone and Bones",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D004173",
"descriptor_name": "Dipodomys",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D007103",
"descriptor_name": "Immobilization",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D010024",
"descriptor_name": "Osteoporosis",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D010805",
"descriptor_name": "Physical Conditioning, Animal",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D051381",
"descriptor_name": "Rats",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D013997",
"descriptor_name": "Time Factors",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2095173856/ngrams",
"open_access": {
"is_oa": false,
"oa_status": "closed",
"oa_url": null,
"any_repository_has_fulltext": false
},
"primary_location": {
"is_oa": false,
"landing_page_url": "https://doi.org/10.1016/0300-9629(96)00025-4",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S126806126",
"display_name": "Comparative Biochemistry and Physiology Part A Physiology",
"issn_l": "0300-9629",
"issn": [
"0300-9629"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/P4310320990",
"host_organization_name": "Elsevier BV",
"host_organization_lineage": [
"https://openalex.org/P4310320990"
],
"host_organization_lineage_names": [
"Elsevier BV"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
"primary_topic": {
"id": "https://openalex.org/T12249",
"display_name": "Orthopedic Studies in Canine Veterinary Medicine",
"score": 0.9788,
"subfield": {
"id": "https://openalex.org/subfields/3404",
"display_name": "Small Animals"
},
"field": {
"id": "https://openalex.org/fields/34",
"display_name": "Veterinary"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
},
"publication_date": "1996-08-01",
"publication_year": 1996,
"referenced_works": [
"https://openalex.org/W1560068742",
"https://openalex.org/W174716201",
"https://openalex.org/W2003783038",
"https://openalex.org/W2047337082",
"https://openalex.org/W2051011382",
"https://openalex.org/W2103720968",
"https://openalex.org/W2150949322",
"https://openalex.org/W2181790860",
"https://openalex.org/W2271608994",
"https://openalex.org/W2312380669",
"https://openalex.org/W2908629052",
"https://openalex.org/W3134417133",
"https://openalex.org/W4302584972",
"https://openalex.org/W657923805",
"https://openalex.org/W94140509"
],
"referenced_works_count": 15,
"related_works": [
"https://openalex.org/W2426807744",
"https://openalex.org/W2407798550",
"https://openalex.org/W2403518672",
"https://openalex.org/W2113590032",
"https://openalex.org/W2087719526",
"https://openalex.org/W2063133063",
"https://openalex.org/W2042190289",
"https://openalex.org/W1966504330",
"https://openalex.org/W1878020629",
"https://openalex.org/W1748928841"
],
"sustainable_development_goals": [
{
"display_name": "Good health and well-being",
"id": "https://metadata.un.org/sdg/3",
"score": 0.41
}
],
"title": "Kangaroo rat bone compared to white rat bone after short-term disuse and exercise",
"topics": [
{
"id": "https://openalex.org/T12249",
"display_name": "Orthopedic Studies in Canine Veterinary Medicine",
"score": 0.9788,
"subfield": {
"id": "https://openalex.org/subfields/3404",
"display_name": "Small Animals"
},
"field": {
"id": "https://openalex.org/fields/34",
"display_name": "Veterinary"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
}
},
{
"id": "https://openalex.org/T11214",
"display_name": "Genetic and Behavioral Studies on Dog Domestication",
"score": 0.9343,
"subfield": {
"id": "https://openalex.org/subfields/1311",
"display_name": "Genetics"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
{
"id": "https://openalex.org/T12674",
"display_name": "Perception and Factors of Rabbit Meat Quality",
"score": 0.9296,
"subfield": {
"id": "https://openalex.org/subfields/1103",
"display_name": "Animal Science and Zoology"
},
"field": {
"id": "https://openalex.org/fields/11",
"display_name": "Agricultural and Biological Sciences"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-13T16:22:21.486335",
"versions": []
}
}
