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OpenAlex: !!python/object/new:pyalex.api.Topic
{
   dictitems:
  "id": "https://openalex.org/T10163",
    cited_by_count: 1971923
   "display_name": "Platinum-Based Cancer Chemotherapy",
    created_date: '2024-01-23'
  "description": "This cluster of papers explores the advancements and challenges in platinum-based cancer chemotherapy, focusing on the molecular mechanisms of action, resistance, and toxicity associated with platinum drugs. It also delves into the development of new metal complexes as potential therapeutics, DNA interactions of metal compounds, and the exploration of ruthenium compounds as anticancer agents.",
    description: This cluster of papers explores the advancements and challenges in
  "keywords": [
      platinum-based cancer chemotherapy, focusing on the molecular mechanisms of
     "Platinum-Based Drugs",
      action, resistance, and toxicity associated with platinum drugs. It also delves
    "Cisplatin Resistance",
      into the development of new metal complexes as potential therapeutics, DNA interactions
    "Metal Complexes",
      of metal compounds, and the exploration of ruthenium compounds as anticancer
    "Anticancer Agents",
      agents.
    "Molecular Mechanisms",
     display_name: Platinum-Based Cancer Chemotherapy
    "DNA Interactions",
     domain:
    "Ruthenium Compounds",
      display_name: Health Sciences
    "Chemical Biology",
      id: https://openalex.org/domains/4
    "Drug Development",
     field:
     "Cellular Processing"
      display_name: Medicine
  ],
      id: https://openalex.org/fields/27
  "ids": {
     id: https://openalex.org/T10163
    "openalex": "https://openalex.org/T10163",
     ids:
     "wikipedia": "https://en.wikipedia.org/wiki/Platinum-based_chemotherapy"
      openalex: https://openalex.org/T10163
  },
      wikipedia: https://en.wikipedia.org/wiki/Platinum-based_chemotherapy
  "subfield": {
     keywords:
     "id": "https://openalex.org/subfields/2730",
    - Platinum-Based Drugs
     "display_name": "Oncology"
    - Cisplatin Resistance
  },
     - Metal Complexes
  "field": {
    - Anticancer Agents
    "id": "https://openalex.org/fields/27",
    - Molecular Mechanisms
    "display_name": "Medicine"
    - DNA Interactions
  },
    - Ruthenium Compounds
  "domain": {
    - Chemical Biology
    "id": "https://openalex.org/domains/4",
    - Drug Development
     "display_name": "Health Sciences"
    - Cellular Processing
  },
    siblings:
  "siblings": [
    - display_name: Advancements in Colorectal Cancer Research
     {
       id: https://openalex.org/T11067
      "id": "https://openalex.org/T11067",
    - display_name: Bisphosphonates in Cancer Treatment and Bone Health
      "display_name": "Advancements in Colorectal Cancer Research"
       id: https://openalex.org/T11221
    },
    - display_name: Cancer Chemopreventive Properties of Saffron
    {
       id: https://openalex.org/T12758
       "id": "https://openalex.org/T11221",
    - display_name: Cancer Immunotherapy
      "display_name": "Bisphosphonates in Cancer Treatment and Bone Health"
       id: https://openalex.org/T10158
    },
    - display_name: Cancer of Unknown Primary Site
    {
       id: https://openalex.org/T12379
       "id": "https://openalex.org/T12758",
    - display_name: Cancer Stem Cells and Tumor Metastasis
      "display_name": "Cancer Chemopreventive Properties of Saffron"
       id: https://openalex.org/T10336
    },
    - display_name: Cancer Survivorship and Quality of Life
    {
       id: https://openalex.org/T10178
       "id": "https://openalex.org/T10158",
    - display_name: Chemotherapy-Induced Peripheral Neuropathy in Cancer Treatment
      "display_name": "Cancer Immunotherapy"
       id: https://openalex.org/T11752
    },
    - display_name: Chimeric Antigen Receptor T Cell Therapy
    {
       id: https://openalex.org/T11491
       "id": "https://openalex.org/T12379",
    - display_name: Colorectal Cancer Research and Treatment
      "display_name": "Cancer of Unknown Primary Site"
       id: https://openalex.org/T10335
    },
    - display_name: Global Cancer Incidence and Mortality Patterns
    {
       id: https://openalex.org/T10556
       "id": "https://openalex.org/T10336",
    - display_name: Global Trends in Colorectal Cancer Research
      "display_name": "Cancer Stem Cells and Tumor Metastasis"
       id: https://openalex.org/T10552
    },
    - display_name: HER2 Signaling in Breast Cancer Treatment
    {
       id: https://openalex.org/T10755
       "id": "https://openalex.org/T10178",
    - display_name: Impact of COVID-19 on Cancer Patients and Care
      "display_name": "Cancer Survivorship and Quality of Life"
       id: https://openalex.org/T11296
    },
    - display_name: Impact of Obesity on Cancer Risk and Prognosis
    {
       id: https://openalex.org/T12103
       "id": "https://openalex.org/T11752",
    - display_name: Inflammation's Role in Cancer Development and Progression
      "display_name": "Chemotherapy-Induced Peripheral Neuropathy in Cancer Treatment"
       id: https://openalex.org/T11355
    },
    - display_name: Lymphangiogenesis in Cancer Metastasis and Disease
    {
       id: https://openalex.org/T11469
       "id": "https://openalex.org/T11491",
    - display_name: Management of Febrile Neutropenia in Cancer Patients
      "display_name": "Chimeric Antigen Receptor T Cell Therapy"
       id: https://openalex.org/T12172
    },
    - display_name: Mechanisms of Multidrug Resistance in Cancer
    {
       id: https://openalex.org/T10570
       "id": "https://openalex.org/T10335",
    - display_name: Melanoma
      "display_name": "Colorectal Cancer Research and Treatment"
       id: https://openalex.org/T10392
    },
    - display_name: Nanotechnology in Cancer Treatment and Diagnosis
    {
       id: https://openalex.org/T13434
       "id": "https://openalex.org/T10556",
    - display_name: Pancreatic Cancer Research and Treatment
      "display_name": "Global Cancer Incidence and Mortality Patterns"
       id: https://openalex.org/T10231
    },
    - display_name: Poly(ADP-ribose) Polymerase Inhibition in Cancer Therapy
    {
       id: https://openalex.org/T11914
       "id": "https://openalex.org/T10552",
    - display_name: Polyomavirus-Associated Carcinogenesis and Clinical Manifestations
      "display_name": "Global Trends in Colorectal Cancer Research"
       id: https://openalex.org/T11827
    },
    - display_name: Role of Chemokine Receptors in Cancer Metastasis
    {
       id: https://openalex.org/T11532
       "id": "https://openalex.org/T10755",
    - display_name: Role of Clusterin in Cancer and Disease
      "display_name": "HER2 Signaling in Breast Cancer Treatment"
       id: https://openalex.org/T14364
    },
    - display_name: Role of Fibroblast Activation in Cancer Progression
    {
       id: https://openalex.org/T12505
       "id": "https://openalex.org/T11296",
    - display_name: Role of STAT3 in Cancer Inflammation and Immunity
      "display_name": "Impact of COVID-19 on Cancer Patients and Care"
       id: https://openalex.org/T11503
    },
    - display_name: Small Cell Lung Cancer
    {
       id: https://openalex.org/T12334
       "id": "https://openalex.org/T12103",
    - display_name: The p53 Signaling Network in Cancer Research
      "display_name": "Impact of Obesity on Cancer Risk and Prognosis"
       id: https://openalex.org/T10583
    },
    - display_name: Tumors of the Ear and Temporal Bone
    {
       id: https://openalex.org/T14326
       "id": "https://openalex.org/T11355",
    - display_name: Vascular Tumors and Angiosarcoma
      "display_name": "Inflammation's Role in Cancer Development and Progression"
       id: https://openalex.org/T12278
    },
    - display_name: Viral-Related Cancers in Immunocompromised Patients
    {
      id: https://openalex.org/T10685
       "id": "https://openalex.org/T11469",
    subfield:
      "display_name": "Lymphangiogenesis in Cancer Metastasis and Disease"
      display_name: Oncology
    },
      id: https://openalex.org/subfields/2730
    {
    updated_date: '2024-05-20T05:20:08.594098'
       "id": "https://openalex.org/T12172",
    works_count: 122649
      "display_name": "Management of Febrile Neutropenia in Cancer Patients"
    },
    {
       "id": "https://openalex.org/T10570",
      "display_name": "Mechanisms of Multidrug Resistance in Cancer"
    },
    {
       "id": "https://openalex.org/T10392",
      "display_name": "Melanoma"
    },
    {
       "id": "https://openalex.org/T13434",
      "display_name": "Nanotechnology in Cancer Treatment and Diagnosis"
    },
    {
       "id": "https://openalex.org/T10231",
      "display_name": "Pancreatic Cancer Research and Treatment"
    },
    {
       "id": "https://openalex.org/T11914",
      "display_name": "Poly(ADP-ribose) Polymerase Inhibition in Cancer Therapy"
    },
    {
       "id": "https://openalex.org/T11827",
      "display_name": "Polyomavirus-Associated Carcinogenesis and Clinical Manifestations"
    },
    {
       "id": "https://openalex.org/T11532",
      "display_name": "Role of Chemokine Receptors in Cancer Metastasis"
    },
    {
       "id": "https://openalex.org/T14364",
      "display_name": "Role of Clusterin in Cancer and Disease"
    },
    {
       "id": "https://openalex.org/T12505",
      "display_name": "Role of Fibroblast Activation in Cancer Progression"
    },
    {
       "id": "https://openalex.org/T11503",
      "display_name": "Role of STAT3 in Cancer Inflammation and Immunity"
    },
    {
       "id": "https://openalex.org/T12334",
      "display_name": "Small Cell Lung Cancer"
    },
    {
       "id": "https://openalex.org/T10583",
      "display_name": "The p53 Signaling Network in Cancer Research"
    },
    {
       "id": "https://openalex.org/T14326",
      "display_name": "Tumors of the Ear and Temporal Bone"
    },
    {
       "id": "https://openalex.org/T12278",
      "display_name": "Vascular Tumors and Angiosarcoma"
    },
    {
       "id": "https://openalex.org/T10685",
      "display_name": "Viral-Related Cancers in Immunocompromised Patients"
    }
  ],
  "works_count": 121707,
  "cited_by_count": 2032478,
  "updated_date": "2024-08-26T05:37:59.863459",
  "created_date": "2024-01-23"
}
Retrieved from "https://geokb.wikibase.cloud/wiki/Special:MobileDiff/1126446"