{
"OpenAlex": {
"id": "https://openalex.org/T13779",
"display_name": "Role of Pim Oncogenes in Tumorigenesis",
"description": "This cluster of papers focuses on the role of Pim oncogenes, particularly Pim-1 and Pim-2 kinases, in promoting tumorigenesis, cancer progression, and metastasis. The cluster also explores the potential of targeting Pim kinases as a therapeutic approach, with a specific emphasis on their involvement in cell survival pathways, phosphorylation of key proteins, and their association with hematological malignancies.",
"keywords": [
"Pim Oncogenes",
"Tumorigenesis",
"Metadherin",
"Astrocyte Elevated Gene-1",
"Kinase Inhibitors",
"Cancer Progression",
"Cell Survival Pathways",
"Phosphorylation",
"Metastasis",
"Hematological Malignancies"
],
"ids": {
"openalex": "https://openalex.org/T13779",
"wikipedia": "https://en.wikipedia.org/wiki/PIM1"
},
"subfield": {
"id": "https://openalex.org/subfields/2734",
"display_name": "Pathology and Forensic Medicine"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
},
"siblings": [
{
"id": "https://openalex.org/T11154",
"display_name": "Biological, Epidemiological, and Clinical Aspects of Echinococcosis"
},
{
"id": "https://openalex.org/T11134",
"display_name": "Breast Pathology and Imaging Techniques"
},
{
"id": "https://openalex.org/T13363",
"display_name": "Clinical and Molecular Characteristics of Glomus Tumors"
},
{
"id": "https://openalex.org/T10137",
"display_name": "Diagnosis and Pathogenesis of Multiple Sclerosis"
},
{
"id": "https://openalex.org/T13383",
"display_name": "Granular Cell Tumor: Clinical and Pathological Characteristics"
},
{
"id": "https://openalex.org/T11318",
"display_name": "Health Effects of Soy Isoflavones and Phytoestrogens"
},
{
"id": "https://openalex.org/T11411",
"display_name": "Health Effects of Tea Polyphenols"
},
{
"id": "https://openalex.org/T10185",
"display_name": "Lymphoid Neoplasms"
},
{
"id": "https://openalex.org/T12429",
"display_name": "Mechanisms and Renoprotective Strategies for Cisplatin Nephrotoxicity"
},
{
"id": "https://openalex.org/T14199",
"display_name": "Medical Serial Killers and Forensic Toxicology"
},
{
"id": "https://openalex.org/T11369",
"display_name": "Molecular Characterization of Colorectal Cancer"
},
{
"id": "https://openalex.org/T14415",
"display_name": "Nephropathic Cystinosis Research"
},
{
"id": "https://openalex.org/T11207",
"display_name": "Pathogenesis and Treatment of Alcoholic Liver Disease"
},
{
"id": "https://openalex.org/T11730",
"display_name": "Pathogenesis and Treatment of Pemphigoid Diseases"
},
{
"id": "https://openalex.org/T11330",
"display_name": "Pathogenesis and Treatment of Systemic Sclerosis"
},
{
"id": "https://openalex.org/T13834",
"display_name": "Pathogenesis and Treatment of Whipple's Disease"
},
{
"id": "https://openalex.org/T12193",
"display_name": "Pathology and Management of Trigeminal Neuralgia"
},
{
"id": "https://openalex.org/T11538",
"display_name": "Pathophysiology and Management of Graves' Ophthalmopathy"
},
{
"id": "https://openalex.org/T10925",
"display_name": "Pathophysiology and Treatment of Spinal Cord Injury"
},
{
"id": "https://openalex.org/T10238",
"display_name": "Pathophysiology of Lumbar Disc Degeneration and Treatment"
},
{
"id": "https://openalex.org/T11057",
"display_name": "Pathophysiology of Myocardial Reperfusion Injury"
},
{
"id": "https://openalex.org/T10277",
"display_name": "Vitamin D and Health Outcomes"
}
],
"works_count": 19500,
"cited_by_count": 209273,
"updated_date": "2024-08-26T05:35:08.044460",
"created_date": "2024-01-23"
}
}