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We evaluated the relationship between pregnancy rates and age, dressed carcass weight, and serological status for brucellosis among bison culled from the central Yellowstone subpopulation during the winters of 1996\u20131997, 2001\u20132002, and 2002\u20132003. A model with only dressed carcass weight was the best predictor of pregnancy status for all ages with the odds of pregnancy increasing by 1.03 (95% CI\u2009=\u20091.02\u20131.04) for every 1-kg increase in weight. We found no effect of age or the serological status for brucellosis on pregnancy rates across age classes; however, we did find a positive association between age and pregnancy rates for bison \u22652 years old. Bison \u22652 years old had an overall pregnancy rate of 65% with markedly different rates in alternate ages for animals between 3 and 7 years old. Pregnancy rates were 0.50 (95% CI\u2009=\u20090.31\u20130.69) for brucellosis positive and 0.57 (95% CI\u2009=\u20090.34\u20130.78) for brucellosis negative 2- and 3-year-olds and 0.74 (95% CI\u2009=\u20090.60\u20130.85) in brucellosis positive and 0.69 (95% CI\u2009=\u20090.49\u20130.85) in brucellosis negative bison \u22654 years old. Only 1 of 21 bison <2 years old was pregnant. Our findings are important to accurately predict the effects of brucellosis on Yellowstone bison population dynamics. 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