{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Analysis of antimycin A by reversed-phase liquid chromatography/nuclear magnetic-resonance spectrometry",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "70006923",
"url": "https://pubs.usgs.gov/publication/70006923"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 70006923
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1021/ac00180a005",
"url": "https://doi.org/10.1021/ac00180a005"
}
],
"journal": {
"@type": "Periodical",
"name": "Analytical Chemistry",
"volumeNumber": "61",
"issueNumber": "5"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Analytical Chemistry"
}
],
"datePublished": "1989",
"dateModified": "2023-03-09",
"abstract": "A mixture of closely related streptomyces fermentation products, antimycin A, Is separated, and the components are identified by using reversed-phase high-performance liquid chromatography with directly linked 400-MHz proton nuclear magnetic resonance detection. Analyses of mixtures of three amino acids, alanine, glycine, and valine, are used to determine optimal measurement conditions. Sensitivity increases of as much as a factor of 3 are achieved, at the expense of some loss in chromatographic resolution, by use of an 80-\u03bcL NMR cell, Instead of a smaller 14-\u03bcL cell. Analysis of the antimycin A mixture, using the optimal analytical high performance liquid chromatography/nuclear magnetic resonance conditions, reveals it to consist of at least 10 closely related components.",
"description": "5 p.",
"publisher": {
"@type": "Organization",
"name": "ACS Publications"
},
"author": [
{
"@type": "Person",
"name": "Abidi, Sharon L.",
"givenName": "Sharon L.",
"familyName": "Abidi"
},
{
"@type": "Person",
"name": "Wilkins, Charles L.",
"givenName": "Charles L.",
"familyName": "Wilkins"
},
{
"@type": "Person",
"name": "Ha, Steven T. K.",
"givenName": "Steven T. K.",
"familyName": "Ha"
}
],
"funder": [
{
"@type": "Organization",
"name": "Upper Midwest Environmental Sciences Center",
"url": "https://www.usgs.gov/centers/upper-midwest-environmental-sciences-center"
}
]
},
"OpenAlex": {
"abstract_inverted_index": {
"A": [
0,
88
],
"mixture": [
1
],
"of": [
2,
33,
35,
52,
58,
65,
73,
79,
85,
104
],
"closely": [
3,
108
],
"related": [
4,
109
],
"streptomyces": [
5
],
"fermentation": [
6
],
"products,": [
7
],
"antimycin": [
8,
87
],
"A,": [
9
],
"is": [
10
],
"separated,": [
11
],
"and": [
12,
41
],
"the": [
13,
63,
86,
91
],
"components": [
14
],
"are": [
15,
43,
60
],
"identified": [
16
],
"by": [
17,
71
],
"using": [
18,
90
],
"reversed-phase": [
19
],
"high-performance": [
20,
94
],
"liquid": [
21,
95
],
"chromatography": [
22
],
"with": [
23
],
"directly": [
24
],
"linked": [
25
],
"400-MHz": [
26
],
"proton": [
27
],
"nuclear": [
28
],
"magnetic": [
29,
97
],
"resonance": [
30,
98
],
"detection.": [
31
],
"Analyses": [
32
],
"mixtures": [
34
],
"three": [
36
],
"amino": [
37
],
"acids,": [
38
],
"alanine,": [
39
],
"glycine,": [
40
],
"valine,": [
42
],
"used": [
44
],
"to": [
45,
102
],
"determine": [
46
],
"optimal": [
47,
92
],
"measurement": [
48
],
"conditions.": [
49
],
"Sensitivity": [
50
],
"increases": [
51
],
"as": [
53,
55
],
"much": [
54
],
"a": [
56,
80
],
"factor": [
57
],
"3": [
59
],
"achieved,": [
61
],
"at": [
62,
105
],
"expense": [
64
],
"some": [
66
],
"loss": [
67
],
"in": [
68
],
"chromatographic": [
69
],
"resolution,": [
70
],
"use": [
72
],
"an": [
74
],
"80-microL": [
75
],
"NMR": [
76
],
"cell,": [
77
],
"instead": [
78
],
"smaller": [
81
],
"14-microL": [
82
],
"cell.": [
83
],
"Analysis": [
84
],
"mixture,": [
89
],
"analytical": [
93
],
"chromatography/nuclear": [
96
],
"conditions,": [
99
],
"reveals": [
100
],
"it": [
101
],
"consist": [
103
],
"least": [
106
],
"10": [
107
],
"components.": [
110
]
},
"apc_list": null,
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5050544350",
"display_name": "Steven T. K. Ha",
"orcid": null
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Steven T. K. Ha",
"raw_affiliation_strings": [],
"affiliations": []
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5062440738",
"display_name": "Charles L. Wilkins",
"orcid": "https://orcid.org/0000-0001-6471-6313"
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Charles L. Wilkins",
"raw_affiliation_strings": [],
"affiliations": []
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5007856414",
"display_name": "S. L. Abidi",
"orcid": null
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Sharon L. Abidi",
"raw_affiliation_strings": [],
"affiliations": []
}
],
"best_oa_location": null,
"biblio": {
"volume": "61",
"issue": "5",
"first_page": "404",
"last_page": "408"
},
"citation_normalized_percentile": {
"value": 0.611859,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2049440317",
"cited_by_count": 9,
"cited_by_percentile_year": {
"min": 78,
"max": 79
},
"concepts": [
{
"id": "https://openalex.org/C185592680",
"wikidata": "https://www.wikidata.org/wiki/Q2329",
"display_name": "Chemistry",
"level": 0,
"score": 0.97795826
},
{
"id": "https://openalex.org/C162356407",
"wikidata": "https://www.wikidata.org/wiki/Q180809",
"display_name": "Mass spectrometry",
"level": 2,
"score": 0.62212354
},
{
"id": "https://openalex.org/C43617362",
"wikidata": "https://www.wikidata.org/wiki/Q170050",
"display_name": "Chromatography",
"level": 1,
"score": 0.5598109
},
{
"id": "https://openalex.org/C2779965811",
"wikidata": "https://www.wikidata.org/wiki/Q104708365",
"display_name": "Antimycin A",
"level": 3,
"score": 0.50602096
},
{
"id": "https://openalex.org/C46141821",
"wikidata": "https://www.wikidata.org/wiki/Q209402",
"display_name": "Nuclear magnetic resonance",
"level": 1,
"score": 0.44345048
},
{
"id": "https://openalex.org/C66974803",
"wikidata": "https://www.wikidata.org/wiki/Q10359898",
"display_name": "Nuclear magnetic resonance spectroscopy",
"level": 2,
"score": 0.436897
},
{
"id": "https://openalex.org/C178790620",
"wikidata": "https://www.wikidata.org/wiki/Q11351",
"display_name": "Organic chemistry",
"level": 1,
"score": 0.08974734
},
{
"id": "https://openalex.org/C55493867",
"wikidata": "https://www.wikidata.org/wiki/Q7094",
"display_name": "Biochemistry",
"level": 1,
"score": 0.054911345
},
{
"id": "https://openalex.org/C121332964",
"wikidata": "https://www.wikidata.org/wiki/Q413",
"display_name": "Physics",
"level": 0,
"score": 0.0
},
{
"id": "https://openalex.org/C24840226",
"wikidata": "https://www.wikidata.org/wiki/Q211016",
"display_name": "Electron transport chain",
"level": 2,
"score": 0.0
}
],
"corresponding_author_ids": [],
"corresponding_institution_ids": [],
"countries_distinct_count": 0,
"counts_by_year": [
{
"year": 2020,
"cited_by_count": 1
},
{
"year": 2019,
"cited_by_count": 1
},
{
"year": 2016,
"cited_by_count": 1
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Analysis of antimycin A by reversed-phase liquid chromatography/nuclear magnetic resonance spectrometry",
"doi": "https://doi.org/10.1021/ac00180a005",
"fulltext_origin": "ngrams",
"fwci": 0.298,
"grants": [],
"has_fulltext": true,
"id": "https://openalex.org/W2049440317",
"ids": {
"openalex": "https://openalex.org/W2049440317",
"doi": "https://doi.org/10.1021/ac00180a005",
"mag": "2049440317",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/2719254"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 0,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/antimycin-a",
"display_name": "Antimycin A",
"score": 0.50602096
},
{
"id": "https://openalex.org/keywords/two-dimensional-chromatography",
"display_name": "Two-Dimensional Chromatography",
"score": 0.489059
}
],
"language": "en",
"locations": [
{
"is_oa": false,
"landing_page_url": "https://doi.org/10.1021/ac00180a005",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S191963794",
"display_name": "Analytical Chemistry",
"issn_l": "0003-2700",
"issn": [
"0003-2700",
"1520-6882"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320006",
"host_organization_name": "American Chemical Society",
"host_organization_lineage": [
"https://openalex.org/P4310320006"
],
"host_organization_lineage_names": [
"American Chemical Society"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/2719254",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 2,
"mesh": [
{
"descriptor_ui": "D000968",
"descriptor_name": "Antimycin A",
"qualifier_ui": "Q000032",
"qualifier_name": "analysis",
"is_major_topic": true
},
{
"descriptor_ui": "D000968",
"descriptor_name": "Antimycin A",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D002851",
"descriptor_name": "Chromatography, High Pressure Liquid",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D009682",
"descriptor_name": "Magnetic Resonance Spectroscopy",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2049440317/ngrams",
"open_access": {
"is_oa": false,
"oa_status": "closed",
"oa_url": null,
"any_repository_has_fulltext": false
},
"primary_location": {
"is_oa": false,
"landing_page_url": "https://doi.org/10.1021/ac00180a005",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S191963794",
"display_name": "Analytical Chemistry",
"issn_l": "0003-2700",
"issn": [
"0003-2700",
"1520-6882"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320006",
"host_organization_name": "American Chemical Society",
"host_organization_lineage": [
"https://openalex.org/P4310320006"
],
"host_organization_lineage_names": [
"American Chemical Society"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
"primary_topic": {
"id": "https://openalex.org/T10908",
"display_name": "Chiral Separation in Chromatography",
"score": 0.9986,
"subfield": {
"id": "https://openalex.org/subfields/1607",
"display_name": "Spectroscopy"
},
"field": {
"id": "https://openalex.org/fields/16",
"display_name": "Chemistry"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
"publication_date": "1989-03-01",
"publication_year": 1989,
"referenced_works": [
"https://openalex.org/W1964840137",
"https://openalex.org/W1965477292",
"https://openalex.org/W1967024467",
"https://openalex.org/W1978290258",
"https://openalex.org/W1983498081",
"https://openalex.org/W1992687757",
"https://openalex.org/W2014626540",
"https://openalex.org/W2018690665",
"https://openalex.org/W2028026617",
"https://openalex.org/W2037743856",
"https://openalex.org/W2047186674",
"https://openalex.org/W2051236656",
"https://openalex.org/W2057960595",
"https://openalex.org/W2063060310",
"https://openalex.org/W2071265437",
"https://openalex.org/W2084200059",
"https://openalex.org/W2124147568",
"https://openalex.org/W2330597215"
],
"referenced_works_count": 18,
"related_works": [
"https://openalex.org/W3200782958",
"https://openalex.org/W2418511525",
"https://openalex.org/W2359497114",
"https://openalex.org/W2292146963",
"https://openalex.org/W2145880044",
"https://openalex.org/W2056056184",
"https://openalex.org/W2035075384",
"https://openalex.org/W2029357468",
"https://openalex.org/W1984585790",
"https://openalex.org/W1483156797"
],
"sustainable_development_goals": [],
"title": "Analysis of antimycin A by reversed-phase liquid chromatography/nuclear magnetic resonance spectrometry",
"topics": [
{
"id": "https://openalex.org/T10908",
"display_name": "Chiral Separation in Chromatography",
"score": 0.9986,
"subfield": {
"id": "https://openalex.org/subfields/1607",
"display_name": "Spectroscopy"
},
"field": {
"id": "https://openalex.org/fields/16",
"display_name": "Chemistry"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T10407",
"display_name": "Lipid Rafts and Membrane Dynamics",
"score": 0.9976,
"subfield": {
"id": "https://openalex.org/subfields/1312",
"display_name": "Molecular Biology"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
}
},
{
"id": "https://openalex.org/T10683",
"display_name": "Mass Spectrometry Techniques",
"score": 0.9971,
"subfield": {
"id": "https://openalex.org/subfields/1607",
"display_name": "Spectroscopy"
},
"field": {
"id": "https://openalex.org/fields/16",
"display_name": "Chemistry"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-15T12:41:37.599687",
"versions": []
}
}