{
"@context": "http://schema.org/", "@type": "WebPage", "additionalType": "Research", "url": "https://www.usgs.gov/programs/environmental-health-program/science/photomicroscopy-and-flow-cytometry-core-technology", "headline": "Photomicroscopy and Flow Cytometry Core Technology Team", "datePublished": "February 28, 2024", "author": [ { "@type": "Person", "name": "Jill Jenkins, Ph.D.", "url": "https://www.usgs.gov/staff-profiles/jill-jenkins", "identifier": { "@type": "PropertyValue", "propertyID": "orcid", "value": "0000-0002-5087-0894" } } ], "description": [ { "@type": "TextObject", "text": "The Photomicroscopy and Flow Cytometry Core Technology Team (CTT) as part of the Environmental Health Program works to develop and apply biomarkers to evaluate the potential impacts of environmental contaminants at cellular and molecular levels. Because molecular and biochemical responses of cells are preceded by chemical changes in nuclei, cytoplasm, membranes, and extracellular fluids, these responses can be indicative of contaminant exposures." }, { "@type": "TextObject", "text": "Data gathered can reflect reproductive status and indicate genotoxicity (relevant to environmental conditions). This information is often integrated with other organism, population and landscape level information and analytical chemistry data to provide information on adverse outcome pathways (i.e., linkages between a direct molecular initiating event and an adverse outcome at a biological level of organization), as well as biomarkers (e.g., early-warning signals that reflect biological responses). These methods can be used in research with bacteria to mammals to deliver actionable science to support environmental health research and goals." }, { "@type": "TextObject", "text": "The CTT uses biotechnologies typically used in human medicine to collect data on animal cells. In general, blood and sperm are used to determine markers of response such as chemical changes in cell structures and DNA, which can indicate animal condition." }, { "@type": "TextObject", "text": "The Photomicroscopy and Flow Cytometry CTT focuses on bioindicators associated with environmental stressors and ecosystem integrity, which are essential to the management of trust resources, habitats, and ecosystems that serve human, and fish and wildlife communities." }, { "@type": "TextObject", "text": "About the Research" } ], "funder": { "@type": "Organization", "name": "Environmental Health Program", "url": "https://www.usgs.gov/programs/environmental-health-program" }, "about": [ { "@type": "Thing", "name": "Water" }, { "@type": "Thing", "name": "Biology" }, { "@type": "Thing", "name": "laboratory" }, { "@type": "Thing", "name": "Core Technology Team" }, { "@type": "Thing", "name": "Land Stewardship" }, { "@type": "Thing", "name": "Methods Development" }, { "@type": "Thing", "name": "Information Systems" }, { "@type": "Thing", "name": "photomicroscopy" }, { "@type": "Thing", "name": "Environmental Health" }, { "@type": "Thing", "name": "Fishing and Hunting" }, { "@type": "Thing", "name": "exposure" }, { "@type": "Thing", "name": "contaminant" }, { "@type": "Thing", "name": "Environmental Toxicology" }, { "@type": "Thing", "name": "Methods and Analysis" }, { "@type": "Thing", "name": "environmental health" }, { "@type": "Thing", "name": "biomarker" }, { "@type": "Thing", "name": "Health Effects" }, { "@type": "Thing", "name": "Geology" }, { "@type": "Thing", "name": "Science Technology" }, { "@type": "Thing", "name": "Disaster Science" }, { "@type": "Thing", "name": "Cyanotoxins and Harmful Algal blooms" }, { "@type": "Thing", "name": "Climate" }, { "@type": "Thing", "name": "Ecosystems" }, { "@type": "Thing", "name": "Energy" }, { "@type": "Thing", "name": "Immunomodulation" }, { "@type": "Thing", "name": "Contaminant Transport and Effects" } ]
}