{
"OpenAlex": {
"display_name": "Amyotrophic Lateral Sclerosis and Frontotemporal Dementia",
"description": "This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases.",
"keywords": [
"TDP-43",
"FUS/TLS",
"C9ORF72",
"mutations",
"neurodegeneration",
"motor neurons",
"RNA processing",
"progranulin",
"ubiquitin-positive inclusions",
"genetics"
],
"ids": {
"openalex": "https://openalex.org/T10855",
"wikipedia": "https://en.wikipedia.org/wiki/Amyotrophic_lateral_sclerosis"
},
"subfield": {
"id": "https://openalex.org/subfields/2728",
"display_name": "Neurology"
},
"field": {
"id": "https://openalex.org/fields/27",
"display_name": "Medicine"
},
"domain": {
"id": "https://openalex.org/domains/4",
"display_name": "Health Sciences"
},
"updated_date": "2024-08-12T05:12:22.326426",
"created_date": "2024-01-23",
"type": "topic",
"oa_id": "T10855",
"id": "https://openalex.org/T10855"
}
}