{
"OpenAlex": {
"display_name": "Prion Diseases: Causes and Molecular Basis",
"description": "This cluster of papers focuses on the causes, molecular basis, detection, transmission, and potential treatments for prion diseases, including variant Creutzfeldt-Jakob disease. It explores the role of infectious prions, protein misfolding, and their impact on neurodegenerative diseases. The research also delves into the pathology of these diseases and their transmissibility through blood transfusion.",
"keywords": [
"Prion Diseases",
"Molecular Basis",
"Pathological Protein Misfolding",
"Variant Creutzfeldt-Jakob Disease",
"Infectious Prions",
"Neurodegenerative Diseases",
"Protein Aggregation",
"Transmissible Spongiform Encephalopathies",
"Cyclic Amplification",
"Cellular Prion Protein"
],
"ids": {
"openalex": "https://openalex.org/T11335",
"wikipedia": "https://en.wikipedia.org/wiki/Prion"
},
"subfield": {
"id": "https://openalex.org/subfields/1312",
"display_name": "Molecular Biology"
},
"field": {
"id": "https://openalex.org/fields/13",
"display_name": "Biochemistry, Genetics and Molecular Biology"
},
"domain": {
"id": "https://openalex.org/domains/1",
"display_name": "Life Sciences"
},
"updated_date": "2024-08-12T05:54:01.332720",
"created_date": "2024-01-23",
"type": "topic",
"oa_id": "T11335",
"id": "https://openalex.org/T11335"
}
}