{
"USGS Publications Warehouse": {
"@context": "https://schema.org",
"@type": "Article",
"additionalType": "Journal Article",
"name": "Egg incubation position affects toxicity of air cell administered polychlorinated biphenyl 126 (3,3\u2032,4,4\u2032,5-pentachlorobiphenyl) in chicken (Gallus gallus) embryos",
"identifier": [
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse IndexID",
"value": "5224842",
"url": "https://pubs.usgs.gov/publication/5224842"
},
{
"@type": "PropertyValue",
"propertyID": "USGS Publications Warehouse Internal ID",
"value": 5224842
},
{
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1897/07-291.1",
"url": "https://doi.org/10.1897/07-291.1"
}
],
"journal": {
"@type": "Periodical",
"name": "Environmental Toxicology and Chemistry",
"volumeNumber": "26",
"issueNumber": "12"
},
"inLanguage": "en",
"isPartOf": [
{
"@type": "CreativeWorkSeries",
"name": "Environmental Toxicology and Chemistry"
}
],
"datePublished": "2007",
"dateModified": "2021-05-26",
"abstract": "The avian egg is used extensively for chemical screening and determining the relative sensitivity of species to environmental contaminants (e.g., metals, pesticides, polyhalogenated compounds). The effect of egg incubation position on embryonic survival, pipping, and hatching success was examined following air cell administration of polychlorinated biphenyl (PCB) congener 126 (3,3',4,4',5-pentachlorobiphenyl [PCB 126]; 500-2,000 pg/g egg) on day 4 of development in fertile chicken (Gallus gallus) eggs. Depending on dose, toxicity was found to be up to nine times greater in vertically versus horizontally incubated eggs. This may be due to enhanced embryonic exposure to the injection bolus in vertically incubated eggs compared to more gradual uptake in horizontally incubated eggs. Following air cell administration of PCB 126, horizontal incubation of eggs may more closely approximate uptake and toxicity that has been observed with naturally incorporated contaminants. These data have implications for chemical screening and use of laboratory data for ecological risk assessments.",
"description": "4 p.",
"publisher": {
"@type": "Organization",
"name": "Wiley"
},
"author": [
{
"@type": "Person",
"name": "Hale, R. C.",
"givenName": "R. C.",
"familyName": "Hale"
},
{
"@type": "Person",
"name": "Ottinger, M. A.",
"givenName": "M. A.",
"familyName": "Ottinger"
},
{
"@type": "Person",
"name": "McKernan, M.A.",
"givenName": "M.A.",
"familyName": "McKernan"
},
{
"@type": "Person",
"name": "Rattner, Barnett A.",
"givenName": "Barnett A.",
"familyName": "Rattner",
"identifier": {
"@type": "PropertyValue",
"propertyID": "ORCID",
"value": "0000-0003-3676-2843",
"url": "https://orcid.org/0000-0003-3676-2843"
},
"affiliation": [
{
"@type": "Organization",
"name": "Eastern Ecological Science Center",
"url": "https://www.usgs.gov/centers/eesc"
}
]
}
],
"funder": [
{
"@type": "Organization",
"name": "Patuxent Wildlife Research Center",
"url": "https://www.usgs.gov/centers/pwrc"
}
]
},
"OpenAlex": {
"abstract_inverted_index": {
"The": [
0,
24
],
"avian": [
1
],
"egg": [
2,
27
],
"is": [
3
],
"used": [
4
],
"extensively": [
5
],
"for": [
6,
140,
148
],
"chemical": [
7,
141
],
"screening": [
8,
142
],
"and": [
9,
34,
126,
143
],
"determining": [
10
],
"the": [
11,
94
],
"relative": [
12
],
"sensitivity": [
13
],
"of": [
14,
26,
43,
58,
114,
119,
145
],
"species": [
15
],
"to": [
16,
72,
75,
89,
93,
102
],
"environmental": [
17
],
"contaminants": [
18
],
"(e.g.,": [
19
],
"metals,": [
20
],
"pesticides,": [
21
],
"polyhalogenated": [
22
],
"compounds).": [
23
],
"effect": [
25
],
"incubation": [
28,
118
],
"position": [
29
],
"on": [
30,
55,
67
],
"embryonic": [
31,
91
],
"survival,": [
32
],
"pipping,": [
33
],
"hatching": [
35
],
"success": [
36
],
"was": [
37,
70
],
"examined": [
38
],
"following": [
39
],
"air": [
40,
111
],
"cell": [
41,
112
],
"administration": [
42,
113
],
"polychlorinated": [
44
],
"biphenyl": [
45
],
"(PCB)": [
46
],
"congener": [
47
],
"126": [
48
],
"(3,3',4,4',5-pentachlorobiphenyl": [
49
],
"[PCB": [
50
],
"126];": [
51
],
"500-2,000": [
52
],
"pg/g": [
53
],
"egg)": [
54
],
"day": [
56
],
"4": [
57
],
"development": [
59
],
"in": [
60,
79,
97,
106
],
"fertile": [
61
],
"chicken": [
62
],
"(Gallus": [
63
],
"gallus)": [
64
],
"eggs.": [
65,
84,
109
],
"Depending": [
66
],
"dose,": [
68
],
"toxicity": [
69,
127
],
"found": [
71
],
"be": [
73,
87
],
"up": [
74
],
"nine": [
76
],
"times": [
77
],
"greater": [
78
],
"vertically": [
80,
98
],
"versus": [
81
],
"horizontally": [
82,
107
],
"incubated": [
83,
99,
108
],
"This": [
85
],
"may": [
86,
121
],
"due": [
88
],
"enhanced": [
90
],
"exposure": [
92
],
"injection": [
95
],
"bolus": [
96
],
"eggs": [
100,
120
],
"compared": [
101
],
"more": [
103,
122
],
"gradual": [
104
],
"uptake": [
105,
125
],
"Following": [
110
],
"PCB": [
115
],
"126,": [
116
],
"horizontal": [
117
],
"closely": [
123
],
"approximate": [
124
],
"that": [
128
],
"has": [
129
],
"been": [
130
],
"observed": [
131
],
"with": [
132
],
"naturally": [
133
],
"incorporated": [
134
],
"contaminants.": [
135
],
"These": [
136
],
"data": [
137,
147
],
"have": [
138
],
"implications": [
139
],
"use": [
144
],
"laboratory": [
146
],
"ecological": [
149
],
"risk": [
150
],
"assessments.": [
151
]
},
"apc_list": {
"value": 3400,
"currency": "USD",
"value_usd": 3400,
"provenance": "doaj"
},
"apc_paid": null,
"authorships": [
{
"author_position": "first",
"author": {
"id": "https://openalex.org/A5034679408",
"display_name": "Moira McKernan",
"orcid": null
},
"institutions": [
{
"id": "https://openalex.org/I66946132",
"display_name": "University of Maryland, College Park",
"ror": "https://ror.org/047s2c258",
"country_code": "US",
"type": "education",
"lineage": [
"https://openalex.org/I66946132"
]
}
],
"countries": [
"US"
],
"is_corresponding": false,
"raw_author_name": "Moira A McKernan",
"raw_affiliation_strings": [
"Marine, Estuarine and Environmental Sciences, University of Maryland, College Park 20742, USA."
],
"affiliations": [
{
"raw_affiliation_string": "Marine, Estuarine and Environmental Sciences, University of Maryland, College Park 20742, USA.",
"institution_ids": [
"https://openalex.org/I66946132"
]
}
]
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5067802153",
"display_name": "Barnett A. Rattner",
"orcid": "https://orcid.org/0000-0003-3676-2843"
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Barnett A Rattner",
"raw_affiliation_strings": [],
"affiliations": []
},
{
"author_position": "middle",
"author": {
"id": "https://openalex.org/A5054047728",
"display_name": "Robert C. Hale",
"orcid": "https://orcid.org/0000-0002-3066-8891"
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Robert C Hale",
"raw_affiliation_strings": [],
"affiliations": []
},
{
"author_position": "last",
"author": {
"id": "https://openalex.org/A5016735317",
"display_name": "Mary Ann Ottinger",
"orcid": "https://orcid.org/0000-0002-5863-3252"
},
"institutions": [],
"countries": [],
"is_corresponding": false,
"raw_author_name": "Mary Ann Ottinger",
"raw_affiliation_strings": [],
"affiliations": []
}
],
"best_oa_location": null,
"biblio": {
"volume": "26",
"issue": "12",
"first_page": "2724",
"last_page": "2727"
},
"citation_normalized_percentile": {
"value": 0.698412,
"is_in_top_1_percent": false,
"is_in_top_10_percent": false
},
"cited_by_api_url": "https://api.openalex.org/works?filter=cites:W2022577104",
"cited_by_count": 21,
"cited_by_percentile_year": {
"min": 88,
"max": 89
},
"concepts": [
{
"id": "https://openalex.org/C2776365360",
"wikidata": "https://www.wikidata.org/wiki/Q211171",
"display_name": "Polychlorinated biphenyl",
"level": 2,
"score": 0.83371276
},
{
"id": "https://openalex.org/C25642318",
"wikidata": "https://www.wikidata.org/wiki/Q1992532",
"display_name": "Incubation",
"level": 2,
"score": 0.81346667
},
{
"id": "https://openalex.org/C29730261",
"wikidata": "https://www.wikidata.org/wiki/Q274160",
"display_name": "Toxicity",
"level": 2,
"score": 0.72971636
},
{
"id": "https://openalex.org/C2777744765",
"wikidata": "https://www.wikidata.org/wiki/Q2734755",
"display_name": "Hatching",
"level": 2,
"score": 0.72517407
},
{
"id": "https://openalex.org/C161176658",
"wikidata": "https://www.wikidata.org/wiki/Q131656",
"display_name": "Pesticide",
"level": 2,
"score": 0.6264869
},
{
"id": "https://openalex.org/C196843134",
"wikidata": "https://www.wikidata.org/wiki/Q33196",
"display_name": "Embryo",
"level": 2,
"score": 0.5791531
},
{
"id": "https://openalex.org/C2780591471",
"wikidata": "https://www.wikidata.org/wiki/Q410915",
"display_name": "Biphenyl",
"level": 2,
"score": 0.57636404
},
{
"id": "https://openalex.org/C86803240",
"wikidata": "https://www.wikidata.org/wiki/Q420",
"display_name": "Biology",
"level": 0,
"score": 0.5163752
},
{
"id": "https://openalex.org/C2779357283",
"wikidata": "https://www.wikidata.org/wiki/Q5160401",
"display_name": "Congener",
"level": 2,
"score": 0.51464903
},
{
"id": "https://openalex.org/C179335377",
"wikidata": "https://www.wikidata.org/wiki/Q5266825",
"display_name": "Developmental toxicity",
"level": 4,
"score": 0.468812
},
{
"id": "https://openalex.org/C33070731",
"wikidata": "https://www.wikidata.org/wiki/Q7218",
"display_name": "Toxicology",
"level": 1,
"score": 0.46360242
},
{
"id": "https://openalex.org/C107872376",
"wikidata": "https://www.wikidata.org/wiki/Q321355",
"display_name": "Environmental chemistry",
"level": 1,
"score": 0.37893727
},
{
"id": "https://openalex.org/C185592680",
"wikidata": "https://www.wikidata.org/wiki/Q2329",
"display_name": "Chemistry",
"level": 0,
"score": 0.3505586
},
{
"id": "https://openalex.org/C140793950",
"wikidata": "https://www.wikidata.org/wiki/Q168091",
"display_name": "Animal science",
"level": 1,
"score": 0.33317345
},
{
"id": "https://openalex.org/C46973012",
"wikidata": "https://www.wikidata.org/wiki/Q28627",
"display_name": "Gestation",
"level": 3,
"score": 0.2769668
},
{
"id": "https://openalex.org/C18903297",
"wikidata": "https://www.wikidata.org/wiki/Q7150",
"display_name": "Ecology",
"level": 1,
"score": 0.18405646
},
{
"id": "https://openalex.org/C2779234561",
"wikidata": "https://www.wikidata.org/wiki/Q11995",
"display_name": "Pregnancy",
"level": 2,
"score": 0.14929745
},
{
"id": "https://openalex.org/C55493867",
"wikidata": "https://www.wikidata.org/wiki/Q7094",
"display_name": "Biochemistry",
"level": 1,
"score": 0.1395871
},
{
"id": "https://openalex.org/C505870484",
"wikidata": "https://www.wikidata.org/wiki/Q180538",
"display_name": "Fishery",
"level": 1,
"score": 0.07613629
},
{
"id": "https://openalex.org/C54355233",
"wikidata": "https://www.wikidata.org/wiki/Q7162",
"display_name": "Genetics",
"level": 1,
"score": 0.0
},
{
"id": "https://openalex.org/C178790620",
"wikidata": "https://www.wikidata.org/wiki/Q11351",
"display_name": "Organic chemistry",
"level": 1,
"score": 0.0
}
],
"corresponding_author_ids": [],
"corresponding_institution_ids": [],
"countries_distinct_count": 1,
"counts_by_year": [
{
"year": 2018,
"cited_by_count": 1
},
{
"year": 2017,
"cited_by_count": 1
},
{
"year": 2016,
"cited_by_count": 1
},
{
"year": 2014,
"cited_by_count": 2
},
{
"year": 2013,
"cited_by_count": 2
},
{
"year": 2012,
"cited_by_count": 1
}
],
"created_date": "2016-06-24",
"datasets": [],
"display_name": "Egg incubation position affects toxicity of air cell administered polychlorinated biphenyl 126 (3,3\u2032,4,4\u2032,5\u2010pentachlorobiphenyl) in chicken (Gallus gallus) embryos",
"doi": "https://doi.org/10.1897/07-291.1",
"fulltext_origin": "ngrams",
"fwci": 1.572,
"grants": [],
"has_fulltext": true,
"id": "https://openalex.org/W2022577104",
"ids": {
"openalex": "https://openalex.org/W2022577104",
"doi": "https://doi.org/10.1897/07-291.1",
"mag": "2022577104",
"pmid": "https://pubmed.ncbi.nlm.nih.gov/18020697"
},
"indexed_in": [
"crossref",
"pubmed"
],
"institutions_distinct_count": 1,
"is_paratext": false,
"is_retracted": false,
"keywords": [
{
"id": "https://openalex.org/keywords/polychlorinated-biphenyl",
"display_name": "Polychlorinated biphenyl",
"score": 0.83371276
},
{
"id": "https://openalex.org/keywords/biphenyl",
"display_name": "Biphenyl",
"score": 0.57636404
},
{
"id": "https://openalex.org/keywords/congener",
"display_name": "Congener",
"score": 0.51464903
},
{
"id": "https://openalex.org/keywords/developmental-toxicity",
"display_name": "Developmental toxicity",
"score": 0.468812
},
{
"id": "https://openalex.org/keywords/toxicity-testing",
"display_name": "Toxicity Testing",
"score": 0.461582
}
],
"language": "en",
"locations": [
{
"is_oa": false,
"landing_page_url": "https://doi.org/10.1897/07-291.1",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S136710263",
"display_name": "Environmental Toxicology and Chemistry",
"issn_l": "0730-7268",
"issn": [
"0730-7268",
"1552-8618"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320595",
"host_organization_name": "Wiley",
"host_organization_lineage": [
"https://openalex.org/P4310320595"
],
"host_organization_lineage_names": [
"Wiley"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
{
"is_oa": false,
"landing_page_url": "https://pubmed.ncbi.nlm.nih.gov/18020697",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S4306525036",
"display_name": "PubMed",
"issn_l": null,
"issn": null,
"is_oa": false,
"is_in_doaj": false,
"is_core": false,
"host_organization": "https://openalex.org/I1299303238",
"host_organization_name": "National Institutes of Health",
"host_organization_lineage": [
"https://openalex.org/I1299303238"
],
"host_organization_lineage_names": [
"National Institutes of Health"
],
"type": "repository"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
}
],
"locations_count": 2,
"mesh": [
{
"descriptor_ui": "D002642",
"descriptor_name": "Chick Embryo",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D010063",
"descriptor_name": "Ovum",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": true
},
{
"descriptor_ui": "D011078",
"descriptor_name": "Polychlorinated Biphenyls",
"qualifier_ui": "Q000633",
"qualifier_name": "toxicity",
"is_major_topic": true
},
{
"descriptor_ui": "D011078",
"descriptor_name": "Polychlorinated Biphenyls",
"qualifier_ui": "Q000008",
"qualifier_name": "administration & dosage",
"is_major_topic": true
},
{
"descriptor_ui": "D018675",
"descriptor_name": "Toxicity Tests",
"qualifier_ui": "Q000379",
"qualifier_name": "methods",
"is_major_topic": true
},
{
"descriptor_ui": "D000818",
"descriptor_name": "Animals",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D002642",
"descriptor_name": "Chick Embryo",
"qualifier_ui": "Q000166",
"qualifier_name": "cytology",
"is_major_topic": false
},
{
"descriptor_ui": "D002642",
"descriptor_name": "Chick Embryo",
"qualifier_ui": "Q000187",
"qualifier_name": "drug effects",
"is_major_topic": false
},
{
"descriptor_ui": "D002642",
"descriptor_name": "Chick Embryo",
"qualifier_ui": "Q000196",
"qualifier_name": "embryology",
"is_major_topic": false
},
{
"descriptor_ui": "D004305",
"descriptor_name": "Dose-Response Relationship, Drug",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D010063",
"descriptor_name": "Ovum",
"qualifier_ui": "Q000187",
"qualifier_name": "drug effects",
"is_major_topic": false
},
{
"descriptor_ui": "D010063",
"descriptor_name": "Ovum",
"qualifier_ui": "Q000254",
"qualifier_name": "growth & development",
"is_major_topic": false
},
{
"descriptor_ui": "D011078",
"descriptor_name": "Polychlorinated Biphenyls",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D013995",
"descriptor_name": "Time",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
},
{
"descriptor_ui": "D018675",
"descriptor_name": "Toxicity Tests",
"qualifier_ui": "",
"qualifier_name": null,
"is_major_topic": false
}
],
"ngrams_url": "https://api.openalex.org/works/W2022577104/ngrams",
"open_access": {
"is_oa": false,
"oa_status": "closed",
"oa_url": null,
"any_repository_has_fulltext": false
},
"primary_location": {
"is_oa": false,
"landing_page_url": "https://doi.org/10.1897/07-291.1",
"pdf_url": null,
"source": {
"id": "https://openalex.org/S136710263",
"display_name": "Environmental Toxicology and Chemistry",
"issn_l": "0730-7268",
"issn": [
"0730-7268",
"1552-8618"
],
"is_oa": false,
"is_in_doaj": false,
"is_core": true,
"host_organization": "https://openalex.org/P4310320595",
"host_organization_name": "Wiley",
"host_organization_lineage": [
"https://openalex.org/P4310320595"
],
"host_organization_lineage_names": [
"Wiley"
],
"type": "journal"
},
"license": null,
"license_id": null,
"version": null,
"is_accepted": false,
"is_published": false
},
"primary_topic": {
"id": "https://openalex.org/T10122",
"display_name": "Impact of Persistent Organic Pollutants on Environment and Health",
"score": 0.9983,
"subfield": {
"id": "https://openalex.org/subfields/2307",
"display_name": "Health, Toxicology and Mutagenesis"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
"publication_date": "2007-12-01",
"publication_year": 2007,
"referenced_works": [
"https://openalex.org/W10384444",
"https://openalex.org/W1993837995",
"https://openalex.org/W1995278160",
"https://openalex.org/W1996416309",
"https://openalex.org/W2003692583",
"https://openalex.org/W2005330377",
"https://openalex.org/W2035241165",
"https://openalex.org/W2036367214",
"https://openalex.org/W2051215363",
"https://openalex.org/W2052798774",
"https://openalex.org/W2054607168",
"https://openalex.org/W2057937323",
"https://openalex.org/W2066294832",
"https://openalex.org/W2081165566",
"https://openalex.org/W2095270023",
"https://openalex.org/W2100509258",
"https://openalex.org/W2131455207",
"https://openalex.org/W2172623394"
],
"referenced_works_count": 18,
"related_works": [
"https://openalex.org/W2169776034",
"https://openalex.org/W2144755352",
"https://openalex.org/W2095445027",
"https://openalex.org/W2065653401",
"https://openalex.org/W2051623641",
"https://openalex.org/W2048540309",
"https://openalex.org/W2041189631",
"https://openalex.org/W2033248946",
"https://openalex.org/W1987202976",
"https://openalex.org/W1981114676"
],
"sustainable_development_goals": [
{
"display_name": "Life on land",
"score": 0.4,
"id": "https://metadata.un.org/sdg/15"
}
],
"title": "Egg incubation position affects toxicity of air cell administered polychlorinated biphenyl 126 (3,3\u2032,4,4\u2032,5\u2010pentachlorobiphenyl) in chicken (Gallus gallus) embryos",
"topics": [
{
"id": "https://openalex.org/T10122",
"display_name": "Impact of Persistent Organic Pollutants on Environment and Health",
"score": 0.9983,
"subfield": {
"id": "https://openalex.org/subfields/2307",
"display_name": "Health, Toxicology and Mutagenesis"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T10686",
"display_name": "Endocrine Disruption by Chemical Exposure",
"score": 0.9973,
"subfield": {
"id": "https://openalex.org/subfields/2307",
"display_name": "Health, Toxicology and Mutagenesis"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
},
{
"id": "https://openalex.org/T10447",
"display_name": "Aquatic Ecotoxicology and Biomarkers of Pollution",
"score": 0.9802,
"subfield": {
"id": "https://openalex.org/subfields/2307",
"display_name": "Health, Toxicology and Mutagenesis"
},
"field": {
"id": "https://openalex.org/fields/23",
"display_name": "Environmental Science"
},
"domain": {
"id": "https://openalex.org/domains/3",
"display_name": "Physical Sciences"
}
}
],
"type": "article",
"type_crossref": "journal-article",
"updated_date": "2024-08-14T00:20:05.918174",
"versions": []
}
}