OpenAlex: !!python/object/new:pyalex.api.Topic
dictitems:
cited_by_count: 184397
created_date: '2024-01-23'
description: This cluster of papers focuses on the immunogenicity of biosimilar
therapeutics, including the validation of bioanalytical methods for assessing
immunogenicity, the impact of manufacturing changes on immunogenicity, and the
clinical outcomes and safety of switching from reference biologics to biosimilars.
The use of dried blood spots for bioanalysis and the regulatory considerations
for biosimilars are also prominent topics within this cluster.
display_name: Immunogenicity of Biosimilar Therapeutics in Drug Development
domain:
display_name: Life Sciences
id: https://openalex.org/domains/1
field:
display_name: Immunology and Microbiology
id: https://openalex.org/fields/24
id: https://openalex.org/T12255
ids:
openalex: https://openalex.org/T12255
wikipedia: https://en.wikipedia.org/wiki/Biosimilar
keywords:
- Biosimilars
- Immunogenicity
- Bioanalytical Methods
- Therapeutic Proteins
- Dried Blood Spots
- Erythropoietin Antibodies
- Monoclonal Antibodies
- Regulatory Guidelines
- Biopharmaceuticals
- Clinical Outcomes
siblings:
- display_name: Genetic Basis of Primary Immunodeficiency Disorders
id: https://openalex.org/T11725
- display_name: Human T-cell Leukemia Virus Type 1 Infection
id: https://openalex.org/T12159
- display_name: Immunobiology of Dendritic Cells
id: https://openalex.org/T10580
- display_name: Immunological Mechanisms in Atherosclerosis Development
id: https://openalex.org/T12955
- display_name: Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface
id: https://openalex.org/T11510
- display_name: Immunological Responses in Aquatic Organisms
id: https://openalex.org/T10506
- display_name: Immunotoxicology in Toxicologic Pathology Research
id: https://openalex.org/T14072
- display_name: Immunotoxin Therapy for Cancer Treatment
id: https://openalex.org/T12477
- display_name: Innate Immune Recognition and Signaling Pathways
id: https://openalex.org/T10371
- display_name: Innate Immunity to Viral Infection
id: https://openalex.org/T11668
- display_name: Innate Lymphoid Cells in Immunity
id: https://openalex.org/T12528
- display_name: Invertebrate Immunity and Host Defense Mechanisms
id: https://openalex.org/T11403
- display_name: Macrophage Activation and Polarization
id: https://openalex.org/T11313
- display_name: Mechanisms of Apoptotic Cell Clearance and Immune Regulation
id: https://openalex.org/T12672
- display_name: Natural Killer Cells in Immunity
id: https://openalex.org/T11020
- display_name: Reciprocal Development of TH17 and Treg Cells
id: https://openalex.org/T10469
- display_name: Regulatory T Cell Development and Function
id: https://openalex.org/T10031
- display_name: Role of Complement System in Immune Response
id: https://openalex.org/T10993
- display_name: Role of Galectins in Immunity and Disease
id: https://openalex.org/T12387
- display_name: Role of Macrophage Migration Inhibitory Factor
id: https://openalex.org/T13254
- display_name: Role of Mast Cells in Immunoregulation and Disease
id: https://openalex.org/T11346
- display_name: Role of Neutrophil Extracellular Traps in Immunity
id: https://openalex.org/T11597
- display_name: Role of Pentraxins in Innate Immunity and Inflammation
id: https://openalex.org/T14245
- display_name: Role of TREM-1 and Endocan in Inflammation
id: https://openalex.org/T14165
- display_name: Trained Immunity in Health and Disease
id: https://openalex.org/T13410
subfield:
display_name: Immunology
id: https://openalex.org/subfields/2403
updated_date: '2024-05-20T05:17:23.196634'
works_count: 28125