{
"id": "https://openalex.org/T13410", "display_name": "Trained Immunity in Health and Disease", "description": "This cluster of papers explores the concept of trained immunity, focusing on the innate immune system's ability to develop memory and provide nonspecific protection against various infections. The research covers topics such as BCG vaccination, epigenetic reprogramming, immunometabolism, and the potential implications for health and disease.", "keywords": [ "Trained Immunity", "Innate Memory", "BCG Vaccination", "Epigenetic Reprogramming", "Immunometabolism", "Non-specific Effects", "Infectious Diseases", "Immune Memory", "Vaccine Effects", "Innate Immune Training" ], "ids": { "openalex": "https://openalex.org/T13410", "wikipedia": "https://en.wikipedia.org/wiki/Trained_immunity" }, "subfield": { "id": "https://openalex.org/subfields/2403", "display_name": "Immunology" }, "field": { "id": "https://openalex.org/fields/24", "display_name": "Immunology and Microbiology" }, "domain": { "id": "https://openalex.org/domains/1", "display_name": "Life Sciences" }, "siblings": [ { "id": "https://openalex.org/T11725", "display_name": "Genetic Basis of Primary Immunodeficiency Disorders" }, { "id": "https://openalex.org/T12159", "display_name": "Human T-cell Leukemia Virus Type 1 Infection" }, { "id": "https://openalex.org/T10580", "display_name": "Immunobiology of Dendritic Cells" }, { "id": "https://openalex.org/T12255", "display_name": "Immunogenicity of Biosimilar Therapeutics in Drug Development" }, { "id": "https://openalex.org/T12955", "display_name": "Immunological Mechanisms in Atherosclerosis Development" }, { "id": "https://openalex.org/T11510", "display_name": "Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface" }, { "id": "https://openalex.org/T10506", "display_name": "Immunological Responses in Aquatic Organisms" }, { "id": "https://openalex.org/T14072", "display_name": "Immunotoxicology in Toxicologic Pathology Research" }, { "id": "https://openalex.org/T12477", "display_name": "Immunotoxin Therapy for Cancer Treatment" }, { "id": "https://openalex.org/T10371", "display_name": "Innate Immune Recognition and Signaling Pathways" }, { "id": "https://openalex.org/T11668", "display_name": "Innate Immunity to Viral Infection" }, { "id": "https://openalex.org/T12528", "display_name": "Innate Lymphoid Cells in Immunity" }, { "id": "https://openalex.org/T11403", "display_name": "Invertebrate Immunity and Host Defense Mechanisms" }, { "id": "https://openalex.org/T11313", "display_name": "Macrophage Activation and Polarization" }, { "id": "https://openalex.org/T12672", "display_name": "Mechanisms of Apoptotic Cell Clearance and Immune Regulation" }, { "id": "https://openalex.org/T11020", "display_name": "Natural Killer Cells in Immunity" }, { "id": "https://openalex.org/T10469", "display_name": "Reciprocal Development of TH17 and Treg Cells" }, { "id": "https://openalex.org/T10031", "display_name": "Regulatory T Cell Development and Function" }, { "id": "https://openalex.org/T10993", "display_name": "Role of Complement System in Immune Response" }, { "id": "https://openalex.org/T12387", "display_name": "Role of Galectins in Immunity and Disease" }, { "id": "https://openalex.org/T13254", "display_name": "Role of Macrophage Migration Inhibitory Factor" }, { "id": "https://openalex.org/T11346", "display_name": "Role of Mast Cells in Immunoregulation and Disease" }, { "id": "https://openalex.org/T11597", "display_name": "Role of Neutrophil Extracellular Traps in Immunity" }, { "id": "https://openalex.org/T14245", "display_name": "Role of Pentraxins in Innate Immunity and Inflammation" }, { "id": "https://openalex.org/T14165", "display_name": "Role of TREM-1 and Endocan in Inflammation" } ], "works_count": 15873, "cited_by_count": 175730, "updated_date": "2024-08-26T06:11:17.343437", "created_date": "2024-01-23"
}