Item talk:Q167231

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 dictitems:
   cited_by_count: 2567171
   created_date: '2024-01-23'
   description: This cluster of papers explores the mechanisms, delivery methods,
     and therapeutic applications of RNA interference (RNAi) in mammalian cells.
     It covers topics such as siRNA delivery, gene silencing, non-viral vectors,
     cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for
     gene therapy. The research also delves into the challenges and future directions
     of RNAi-based therapeutics.
   display_name: Mechanisms and Applications of RNA Interference
   domain:
     display_name: Life Sciences
     id: https://openalex.org/domains/1
   field:
     display_name: Biochemistry, Genetics and Molecular Biology
     id: https://openalex.org/fields/13
   id: https://openalex.org/T10725
   ids:
     openalex: https://openalex.org/T10725
     wikipedia: https://en.wikipedia.org/wiki/RNA_interference
   keywords:
   - RNA Interference
   - siRNA Delivery
   - Gene Silencing
   - Non-viral Vectors
   - Therapeutic RNAi
   - Cell-penetrating Peptides
   - Lipid Nanoparticles
   - siRNA Therapeutics
   - Gene Therapy
   - Nucleic Acid Delivery
   siblings:
   - display_name: '14-3-3 Proteins: Structure, Function, and Regulation'
     id: https://openalex.org/T13526
   - display_name: Advances in Metabolomics Research
     id: https://openalex.org/T10836
   - display_name: Analysis of Gene Interaction Networks
     id: https://openalex.org/T10887
   - display_name: ATP Synthase Function and Regulation
     id: https://openalex.org/T12763
   - display_name: Bacterial Biofilms and Quorum Sensing Mechanisms
     id: https://openalex.org/T10593
   - display_name: Bioactive Limonoids in Medicinal Plants
     id: https://openalex.org/T12685
   - display_name: Bioactive Peptides in Food and Health
     id: https://openalex.org/T11561
   - display_name: Bioactivity of Steroidal Saponins in Medicinal Plants
     id: https://openalex.org/T12215
   - display_name: Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids
     id: https://openalex.org/T13188
   - display_name: Biochemistry, Pharmacology, and Medical Use of Bromelain
     id: https://openalex.org/T13725
   - display_name: Biogenesis and Functions of Circular RNAs
     id: https://openalex.org/T11765
   - display_name: Biological Activities of Diterpenoids from Medicinal Plants
     id: https://openalex.org/T12530
   - display_name: Biological Activities of Phenothiazines and Related Compounds
     id: https://openalex.org/T13454
   - display_name: Biological Activities of Prenylated Flavonoids
     id: https://openalex.org/T12257
   - display_name: Biological Activities of Triterpenoids and Saponins
     id: https://openalex.org/T11385
   - display_name: Biological Activity of Diterpenoids and Biflavonoids
     id: https://openalex.org/T13221
   - display_name: Biological Agents for Bioterrorism
     id: https://openalex.org/T11515
   - display_name: Biological Methane Utilization and Metabolism
     id: https://openalex.org/T12688
   - display_name: Bioluminescence Imaging and Reporter Systems
     id: https://openalex.org/T12561
   - display_name: Biomedical Ontologies and Text Mining
     id: https://openalex.org/T11710
   - display_name: Biosynthesis and Engineering of Terpenoids
     id: https://openalex.org/T11882
   - display_name: Biosynthesis and Pharmacological Activities of Lignans
     id: https://openalex.org/T12360
   - display_name: Calcineurin-NFAT Signaling in Transcriptional Regulation
     id: https://openalex.org/T12620
   - display_name: Challenges and Innovations in Bioinformatics Education
     id: https://openalex.org/T13937
   - display_name: Chitin Metabolism in Insects and Mammals
     id: https://openalex.org/T12683
   - display_name: Chromatin Remodeling in Cancer and Development
     id: https://openalex.org/T12820
   - display_name: Clustered Regularly Interspaced Short Palindromic Repeats and
       CRISPR-associated proteins
     id: https://openalex.org/T10878
   - display_name: Comprehensive Integration of Single-Cell Transcriptomic Data
     id: https://openalex.org/T11289
   - display_name: Cyclotide Bioengineering and Protein Anchoring Mechanisms
     id: https://openalex.org/T13326
   - display_name: Diversity and Function of Gut Microbiome
     id: https://openalex.org/T10066
   - display_name: Diversity and Systematics of Yeasts
     id: https://openalex.org/T12668
   - display_name: DNA Barcoding for Food Authentication and Fraud Detection
     id: https://openalex.org/T12388
   - display_name: DNA Nanotechnology and Bioanalytical Applications
     id: https://openalex.org/T10207
   - display_name: 'DNA Topoisomerases: Structure, Function, and Inhibition'
     id: https://openalex.org/T11845
   - display_name: DNA-based Computing and Data Storage
     id: https://openalex.org/T12029
   - display_name: Elicitor Signal Transduction for Metabolite Production
     id: https://openalex.org/T10240
   - display_name: Enzyme Immobilization Techniques
     id: https://openalex.org/T10404
   - display_name: Epigenetic Modifications and Their Functional Implications
     id: https://openalex.org/T10269
   - display_name: Exosome Biology and Function in Intercellular Communication
     id: https://openalex.org/T10773
   - display_name: Fibroblast Growth Factor Signaling Pathway
     id: https://openalex.org/T12287
   - display_name: Functions and Regulation of RNA Editing by ADARs
     id: https://openalex.org/T12610
   - display_name: G-Quadruplex DNA Structures and Functions
     id: https://openalex.org/T10432
   - display_name: Genomic Expression and Function in Yeast Organism
     id: https://openalex.org/T10497
   - display_name: Genomic Signal Processing and Analysis Techniques
     id: https://openalex.org/T12946
   - display_name: Global Diversity of Microbial Eukaryotes and Their Evolution
     id: https://openalex.org/T11879
   - display_name: Glycosylation in Health and Disease
     id: https://openalex.org/T10602
   - display_name: Hedgehog Signaling in Development and Cancer
     id: https://openalex.org/T12009
   - display_name: Heme Oxygenase and Carbon Monoxide Research
     id: https://openalex.org/T11848
   - display_name: Induction and Differentiation of Pluripotent Stem Cells
     id: https://openalex.org/T10505
   - display_name: Lipid Rafts and Membrane Dynamics
     id: https://openalex.org/T10407
   - display_name: Magnetosome Formation in Prokaryotes
     id: https://openalex.org/T11786
   - display_name: Mammalian MAP Kinase Signaling Pathways
     id: https://openalex.org/T11533
   - display_name: Metabolic Engineering and Synthetic Biology
     id: https://openalex.org/T10932
   - display_name: Metabolism and Functions of Coenzyme Q
     id: https://openalex.org/T13012
   - display_name: Microarray Data Analysis and Gene Expression Profiling
     id: https://openalex.org/T10885
   - display_name: Microbial Production of Polyglutamic Acid
     id: https://openalex.org/T14285
   - display_name: Microbial Transformation of Steroids
     id: https://openalex.org/T13736
   - display_name: Mitochondrial Dynamics and Reactive Oxygen Species Regulation
     id: https://openalex.org/T10301
   - display_name: Molecular Biology of Steroidogenesis and Disorders
     id: https://openalex.org/T11956
   - display_name: Molecular Chaperones in Protein Folding and Disease
     id: https://openalex.org/T10934
   - display_name: Molecular Mechanisms and Medical Applications of Ginseng
     id: https://openalex.org/T11889
   - display_name: Molecular Mechanisms of Amyloidosis
     id: https://openalex.org/T11305
   - display_name: Molecular Mechanisms of Angiogenesis and Vascular Function
     id: https://openalex.org/T10422
   - display_name: Molecular Mechanisms of Apoptosis and Cell Death
     id: https://openalex.org/T10294
   - display_name: Molecular Mechanisms of Aquaporins in Physiology and Disease
     id: https://openalex.org/T10724
   - display_name: Molecular Mechanisms of Cardiac Development and Regeneration
     id: https://openalex.org/T11677
   - display_name: Molecular Mechanisms of DNA Damage Response
     id: https://openalex.org/T10123
   - display_name: Molecular Mechanisms of Flavonoid Biosynthesis in Plants
     id: https://openalex.org/T11237
   - display_name: Molecular Mechanisms of Heme Biosynthesis and Related Disorders
     id: https://openalex.org/T12441
   - display_name: Molecular Mechanisms of Inflammasome Activation and Regulation
     id: https://openalex.org/T11078
   - display_name: Molecular Mechanisms of Insect Resistance to Xenobiotics
     id: https://openalex.org/T11075
   - display_name: Molecular Mechanisms of Ion Channels Regulation
     id: https://openalex.org/T10493
   - display_name: Molecular Mechanisms of Kidney Development and Disease
     id: https://openalex.org/T12140
   - display_name: Molecular Mechanisms of Metastasis Suppressor Genes
     id: https://openalex.org/T13437
   - display_name: Molecular Mechanisms of Muscle Regeneration and Atrophy
     id: https://openalex.org/T10441
   - display_name: Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling
     id: https://openalex.org/T11219
   - display_name: Molecular Mechanisms of Photosynthesis and Photoprotection
     id: https://openalex.org/T10303
   - display_name: Molecular Mechanisms of Planarian Regeneration
     id: https://openalex.org/T12789
   - display_name: Molecular Mechanisms of Pollen Development and Function
     id: https://openalex.org/T11927
   - display_name: Molecular Mechanisms of Ras Signaling Pathways
     id: https://openalex.org/T10169
   - display_name: Molecular Mechanisms of Retinal Degeneration and Regeneration
     id: https://openalex.org/T10691
   - display_name: Molecular Mechanisms of Tooth Development and Morphogenesis
     id: https://openalex.org/T11919
   - display_name: Molecular Regulation and Clinical Applications of PDEs
     id: https://openalex.org/T12434
   - display_name: Molecular Regulation of Sulfur Metabolism in Plants
     id: https://openalex.org/T12566
   - display_name: Molecular Systematics of Gesneriaceae and Allies
     id: https://openalex.org/T14049
   - display_name: mTOR Signaling in Growth and Disease
     id: https://openalex.org/T10952
   - display_name: Notch Signaling Pathway in Development and Disease
     id: https://openalex.org/T10268
   - display_name: Nucleotide Metabolism and Enzyme Regulation
     id: https://openalex.org/T12827
   - display_name: Oxidation States in Biochemistry and Medicine
     id: https://openalex.org/T14135
   - display_name: Peptide Synthesis and Drug Discovery
     id: https://openalex.org/T10911
   - display_name: Peroxisome Proliferator-Activated Receptors
     id: https://openalex.org/T11072
   - display_name: Polyamines and Biogenic Amines in Biology and Health
     id: https://openalex.org/T11924
   - display_name: Prediction of Peptide-MHC Binding Affinity
     id: https://openalex.org/T12576
   - display_name: Prediction of Protein Subcellular Localization
     id: https://openalex.org/T12254
   - display_name: 'Prion Diseases: Causes and Molecular Basis'
     id: https://openalex.org/T11335
   - display_name: Protein Aggregation and Biopharmaceutical Stability
     id: https://openalex.org/T11124
   - display_name: Protein Arginine Methylation in Mammals
     id: https://openalex.org/T13157
   - display_name: Protein Binding Specificity in Human Serum Albumin
     id: https://openalex.org/T11908
   - display_name: Protein Microarray Technology and Applications
     id: https://openalex.org/T12867
   - display_name: Protein Structure Prediction and Analysis
     id: https://openalex.org/T10044
   - display_name: Protein Tyrosine Phosphatases in Human Health and Disease
     id: https://openalex.org/T12104
   - display_name: Protein-DNA Interaction Dynamics in Living Cells
     id: https://openalex.org/T13187
   - display_name: 'Pyrrolizidine Alkaloids: Toxicity, Metabolism, and Health Implications'
     id: https://openalex.org/T12756
   - display_name: Real-Time Polymerase Chain Reaction
     id: https://openalex.org/T11970
   - display_name: Recombinant Protein Production in Mammalian and Insect Cells
     id: https://openalex.org/T11663
   - display_name: Redox Signaling and Oxidative Stress
     id: https://openalex.org/T11884
   - display_name: Regulation and Functions of FoxO Transcription Factors
     id: https://openalex.org/T12835
   - display_name: Regulation of Chromatin Structure and Function
     id: https://openalex.org/T10222
   - display_name: Regulation of RNA Processing and Function
     id: https://openalex.org/T10604
   - display_name: Research on Rhodiola rosea and Salidroside
     id: https://openalex.org/T13651
   - display_name: Research on Synthetic Phosphoethanolamine and its Effects
     id: https://openalex.org/T14065
   - display_name: Ribosome Structure and Translation Mechanisms
     id: https://openalex.org/T10521
   - display_name: RNA Methylation and Modification in Gene Expression
     id: https://openalex.org/T11482
   - display_name: RNA Sequencing Data Analysis
     id: https://openalex.org/T10015
   - display_name: Role of AMP-Activated Protein Kinase in Cellular Metabolism
     id: https://openalex.org/T11339
   - display_name: Role of Carbonic Anhydrases in Medicine and Biotechnology
     id: https://openalex.org/T12412
   - display_name: Role of CCN Proteins in Signaling Pathways
     id: https://openalex.org/T13223
   - display_name: Role of Glutathione in Oxidative Stress Response
     id: https://openalex.org/T12187
   - display_name: Role of Histone Deacetylases in Cellular Regulation
     id: https://openalex.org/T11736
   - display_name: Role of Nrf2 Signaling in Oxidative Stress Response
     id: https://openalex.org/T11332
   - display_name: Role of Retinoic Acid in Biological Processes
     id: https://openalex.org/T11559
   - display_name: Role of Sigma Receptors in Cellular Signaling
     id: https://openalex.org/T13047
   - display_name: Role of Transcription Factors in Cell Regulation
     id: https://openalex.org/T13426
   - display_name: 'S100 Proteins: Structure, Function, and Pathology'
     id: https://openalex.org/T12030
   - display_name: Sphingolipid Signalling and Metabolism in Health and Disease
     id: https://openalex.org/T11308
   - display_name: Stochasticity in Gene Regulatory Networks
     id: https://openalex.org/T10621
   - display_name: Structure and Function of G Protein-Coupled Receptors
     id: https://openalex.org/T11178
   - display_name: Structure and Function of Gap Junctions and Connexins
     id: https://openalex.org/T11480
   - display_name: Structure and Function of Nicotinic Receptors
     id: https://openalex.org/T11818
   - display_name: Structure and Function of the Nuclear Pore Complex
     id: https://openalex.org/T11841
   - display_name: Targeted Protein Degradation in Biomedical Research
     id: https://openalex.org/T12534
   - display_name: Transforming Growth Factor Beta Signaling Pathway
     id: https://openalex.org/T11501
   - display_name: Ubiquitin-Proteasome Proteolytic Pathway
     id: https://openalex.org/T11041
   - display_name: Wnt Signaling in Development and Disease
     id: https://openalex.org/T10929
   subfield:
     display_name: Molecular Biology
     id: https://openalex.org/subfields/1312
   updated_date: '2024-05-20T05:10:53.339432'
   works_count: 90229
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