Item talk:Q47361: Difference between revisions
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orcid: | |||
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value: Comparative Susceptibilities of Selected California Chinook | |||
Salmon and Steelhead Populations to Isolates of L Genogroup Infectious | |||
Hematopoietic Necrosis Virus (IHNV) | |||
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value: Shedding Kinetics of Infectious Hematopoietic Necrosis Virus | |||
(IHNV) in Juvenile Spring- and Fall-Run Chinook Salmon of the Columbia | |||
River Basin | |||
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Revision as of 17:39, 20 October 2023
orcid:
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usgs_staff_profile:
meta: status_code: 200 timestamp: '2023-09-30T17:06:19.240816' url: https://www.usgs.gov/staff-profiles/gael-kurath profile: abstracts: [] affiliations: - University of Washington, affiliate faculty in Pathobiology with graduate faculty status. 1994 to Present (full professor since 2017). - University of Washington, affiliate faculty in the School of Aquatic and Fisheries Sciences with graduate faculty status (2007 to Present). - International Committee on Taxonomy of Viruses, member of study groups Rhabdovirus family (1997 to Present), Paramyxovirus Family (2008 to present), and Mononegavirales Super-family (2008 to Present). - International Committee on Taxonomy of Viruses, member of study groups Rhabdovirus family (1997 to Present), Paramyxovirus Family (2008 to present), and Mononegavirales Super-family (2008 to Present). - 'Scientific Journal Editorial Board: Virology (1995-1998); Journal of Aquatic Animal Health (2002-2005); Diseases of Aquatic Organisms (2011-2015); Journal of General Virology (2011-2016).' - Ad hoc reviewer for numerous journals. - 'Grant review panel member or panel chair: USDA Biotechnology Risk Assessment (1996, 1997); USDA NRI Virology (1999, 2000); USDA-NIFA AFRI Diseases of Agricultural Animals program (2020).' - American Fisheries Society, Fish Health Section, member since 1994, nominating/balloting committee member 2002-2003; chair 2004. - American Fisheries Society, Fish Health Section, elected vice-president 2006, executive committee 2006-2010, president 2008. - American Society for Virology member since 1983. education: - Ph.D. 1985. Virology, Oregon State University, Corvallis, OR - M.S. 1980. Marine Microbiology, Oregon State University, Corvallis, OR - B.A. 1978. Microbiology, Miami University, Oxford, OH email: gkurath@usgs.gov expertise_terms: - Virology - RNA Virus Evolution - Ecology and Evolution of infectious Disease - Aquatic Animal Health honors: - Special Achievement Award, American Fisheries, Society Fish Health Section, 1999 - U.S. Department of the Interior Star Awards, 2000, 2003, 2004, 2008 - Snieszko Distinguished Service Award, Fish Health Section, American Fisheries Society, 2020 intro_statements: - Viruses and infectious diseases are natural components of every ecosystem. In aquatic ecosystems of the Pacific Northwest infectious hematopoietic necrosis virus (IHNV) is a significant viral pathogen of many salmonid fish populations. Studies of IHNV molecular biology, pathogenesis, field ecology, and evolution contribute to understanding and management of viral disease in salmon and trout. name: Gael Kurath, Ph.D. name_qualifier: null orcid: 0000-0003-3294-560X organization_link: https://www.usgs.gov/centers/western-fisheries-research-center organization_name: Western Fisheries Research Center personal_statement: Research Interests:Our research involves viral diseases in finfish, with an emphasis on the rhabdovirus IHNV in Pacific salmon and trout of Pacific Northwest ecosystems. We conduct landscape-scale genetic typing of IHNV as it occurs across Western North America and use phylogenetic analyses and molecular epidemiology to identify patterns of virus occurrence, transmission, and disease impacts across large geographic regions, and over many years. This has revealed divergence of IHNV into three major genetic groups (U, M, or L) with distinct host specificities and geographic ranges in North America. There is also clear evidence for viral host jumps, displacement events, and evolution of both specialist and generalist virus lineages. Potential drivers of these evolutionary events are tested in controlled wet laboratory challenge studies in salmonid fish, providing sound scientific data on the biological basis of patterns observed in the field. In a recent project we demonstrated evolution of increasing virulence as a driver of viral genotype displacements in steelhead trout of the Columbia River Basin and worked with collaborators to develop the first landscape-scale transmission model for IHNV. We also explore the biological basis of specialist (adapted to single host species) and generalist (adapted to multiple host species) viruses, using naturally evolved subgroups of IHNV. This has potential to explain changes in virus types and disease impacts observed in the Columbia River Basin, and it also serves as a tractable research model for empirical testing of predictions of basic specialist-generalist theory for pathogens. Finally, we collaborate with other researchers to investigate the evolution of IHNV virulence after a historical host jump from sockeye salmon to farmed rainbow trout using a historical panel of over 60 IHNV isolates collected over the last 50 years. Long-term interests include understanding drivers of viral evolution and ecology, host and virus factors that define virus transmission and transmission models, and how human activities can be modified to avoid unintended disease consequences. professional_experience: - 1992 to Present - Research Microbiologist, U.S. Geological Survey, Western Fisheries Research Center, Seattle, WA - 1989 - 1992 - Postdoctoral researcher, Plant Virology, University of California, Riverside, CA - 1985 - 1988 - Postdoctoral researcher, Plant Virology, Cornell University, Ithaca, NY title: Research Microbiologist