Item talk:Q167231: Difference between revisions

From geokb
No edit summary
(Replaced content with "{ "OpenAlex": { "display_name": "Mechanisms and Applications of RNA Interference", "description": "This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and fut...")
Tag: Replaced
 
Line 1: Line 1:
{
{
   "id": "https://openalex.org/T10725",
   "OpenAlex": {
  "display_name": "Mechanisms and Applications of RNA Interference",
    "display_name": "Mechanisms and Applications of RNA Interference",
  "description": "This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.",
    "description": "This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.",
  "keywords": [
    "keywords": [
    "RNA Interference",
      "RNA Interference",
    "siRNA Delivery",
      "siRNA Delivery",
    "Gene Silencing",
      "Gene Silencing",
    "Non-viral Vectors",
      "Non-viral Vectors",
    "Therapeutic RNAi",
      "Therapeutic RNAi",
    "Cell-penetrating Peptides",
      "Cell-penetrating Peptides",
    "Lipid Nanoparticles",
      "Lipid Nanoparticles",
    "siRNA Therapeutics",
      "siRNA Therapeutics",
    "Gene Therapy",
      "Gene Therapy",
    "Nucleic Acid Delivery"
      "Nucleic Acid Delivery"
  ],
    ],
  "ids": {
    "ids": {
    "openalex": "https://openalex.org/T10725",
      "openalex": "https://openalex.org/T10725",
    "wikipedia": "https://en.wikipedia.org/wiki/RNA_interference"
      "wikipedia": "https://en.wikipedia.org/wiki/RNA_interference"
  },
  "subfield": {
    "id": "https://openalex.org/subfields/1312",
    "display_name": "Molecular Biology"
  },
  "field": {
    "id": "https://openalex.org/fields/13",
    "display_name": "Biochemistry, Genetics and Molecular Biology"
  },
  "domain": {
    "id": "https://openalex.org/domains/1",
    "display_name": "Life Sciences"
  },
  "siblings": [
    {
      "id": "https://openalex.org/T13526",
      "display_name": "14-3-3 Proteins: Structure, Function, and Regulation"
     },
     },
     {
     "subfield": {
       "id": "https://openalex.org/T10836",
       "id": "https://openalex.org/subfields/1312",
       "display_name": "Advances in Metabolomics Research"
       "display_name": "Molecular Biology"
     },
     },
     {
     "field": {
       "id": "https://openalex.org/T10887",
       "id": "https://openalex.org/fields/13",
       "display_name": "Analysis of Gene Interaction Networks"
       "display_name": "Biochemistry, Genetics and Molecular Biology"
     },
     },
     {
     "domain": {
       "id": "https://openalex.org/T12763",
       "id": "https://openalex.org/domains/1",
       "display_name": "ATP Synthase Function and Regulation"
       "display_name": "Life Sciences"
     },
     },
     {
     "updated_date": "2024-08-12T05:58:21.955857",
      "id": "https://openalex.org/T10593",
     "created_date": "2024-01-23",
      "display_name": "Bacterial Biofilms and Quorum Sensing Mechanisms"
     "type": "topic",
    },
     "oa_id": "T10725",
    {
     "id": "https://openalex.org/T10725"
      "id": "https://openalex.org/T12685",
  }
      "display_name": "Bioactive Limonoids in Medicinal Plants"
    },
    {
      "id": "https://openalex.org/T11561",
      "display_name": "Bioactive Peptides in Food and Health"
    },
    {
      "id": "https://openalex.org/T12215",
      "display_name": "Bioactivity of Steroidal Saponins in Medicinal Plants"
    },
    {
      "id": "https://openalex.org/T13188",
      "display_name": "Biochemical and Pharmacological Functions of Beta-Carboline Alkaloids"
    },
    {
      "id": "https://openalex.org/T13725",
      "display_name": "Biochemistry, Pharmacology, and Medical Use of Bromelain"
    },
    {
      "id": "https://openalex.org/T11765",
      "display_name": "Biogenesis and Functions of Circular RNAs"
    },
    {
      "id": "https://openalex.org/T12530",
      "display_name": "Biological Activities of Diterpenoids from Medicinal Plants"
    },
    {
      "id": "https://openalex.org/T13454",
      "display_name": "Biological Activities of Phenothiazines and Related Compounds"
    },
    {
      "id": "https://openalex.org/T12257",
      "display_name": "Biological Activities of Prenylated Flavonoids"
    },
    {
      "id": "https://openalex.org/T11385",
      "display_name": "Biological Activities of Triterpenoids and Saponins"
    },
    {
      "id": "https://openalex.org/T13221",
      "display_name": "Biological Activity of Diterpenoids and Biflavonoids"
    },
    {
      "id": "https://openalex.org/T11515",
      "display_name": "Biological Agents for Bioterrorism"
    },
    {
      "id": "https://openalex.org/T12688",
      "display_name": "Biological Methane Utilization and Metabolism"
    },
    {
      "id": "https://openalex.org/T12561",
      "display_name": "Bioluminescence Imaging and Reporter Systems"
    },
    {
      "id": "https://openalex.org/T11710",
      "display_name": "Biomedical Ontologies and Text Mining"
    },
    {
      "id": "https://openalex.org/T11882",
      "display_name": "Biosynthesis and Engineering of Terpenoids"
    },
    {
      "id": "https://openalex.org/T12360",
      "display_name": "Biosynthesis and Pharmacological Activities of Lignans"
    },
    {
      "id": "https://openalex.org/T12620",
      "display_name": "Calcineurin-NFAT Signaling in Transcriptional Regulation"
    },
    {
      "id": "https://openalex.org/T13937",
      "display_name": "Challenges and Innovations in Bioinformatics Education"
    },
     {
      "id": "https://openalex.org/T12683",
      "display_name": "Chitin Metabolism in Insects and Mammals"
    },
    {
      "id": "https://openalex.org/T12820",
      "display_name": "Chromatin Remodeling in Cancer and Development"
    },
    {
      "id": "https://openalex.org/T10878",
      "display_name": "Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-associated proteins"
    },
    {
      "id": "https://openalex.org/T11289",
      "display_name": "Comprehensive Integration of Single-Cell Transcriptomic Data"
    },
     {
      "id": "https://openalex.org/T13326",
      "display_name": "Cyclotide Bioengineering and Protein Anchoring Mechanisms"
    },
     {
      "id": "https://openalex.org/T10066",
      "display_name": "Diversity and Function of Gut Microbiome"
     },
    {
      "id": "https://openalex.org/T12668",
      "display_name": "Diversity and Systematics of Yeasts"
    },
    {
      "id": "https://openalex.org/T12388",
      "display_name": "DNA Barcoding for Food Authentication and Fraud Detection"
    },
    {
      "id": "https://openalex.org/T10207",
      "display_name": "DNA Nanotechnology and Bioanalytical Applications"
    },
    {
      "id": "https://openalex.org/T11845",
      "display_name": "DNA Topoisomerases: Structure, Function, and Inhibition"
    },
    {
      "id": "https://openalex.org/T12029",
      "display_name": "DNA-based Computing and Data Storage"
    },
    {
      "id": "https://openalex.org/T10240",
      "display_name": "Elicitor Signal Transduction for Metabolite Production"
    },
    {
      "id": "https://openalex.org/T10404",
      "display_name": "Enzyme Immobilization Techniques"
    },
    {
      "id": "https://openalex.org/T10269",
      "display_name": "Epigenetic Modifications and Their Functional Implications"
    },
    {
      "id": "https://openalex.org/T10773",
      "display_name": "Exosome Biology and Function in Intercellular Communication"
    },
    {
      "id": "https://openalex.org/T12287",
      "display_name": "Fibroblast Growth Factor Signaling Pathway"
    },
    {
      "id": "https://openalex.org/T12610",
      "display_name": "Functions and Regulation of RNA Editing by ADARs"
    },
    {
      "id": "https://openalex.org/T10432",
      "display_name": "G-Quadruplex DNA Structures and Functions"
    },
    {
      "id": "https://openalex.org/T10497",
      "display_name": "Genomic Expression and Function in Yeast Organism"
    },
    {
      "id": "https://openalex.org/T12946",
      "display_name": "Genomic Signal Processing and Analysis Techniques"
    },
    {
      "id": "https://openalex.org/T11879",
      "display_name": "Global Diversity of Microbial Eukaryotes and Their Evolution"
    },
    {
      "id": "https://openalex.org/T10602",
      "display_name": "Glycosylation in Health and Disease"
    },
    {
      "id": "https://openalex.org/T12009",
      "display_name": "Hedgehog Signaling in Development and Cancer"
    },
    {
      "id": "https://openalex.org/T11848",
      "display_name": "Heme Oxygenase and Carbon Monoxide Research"
    },
    {
      "id": "https://openalex.org/T10505",
      "display_name": "Induction and Differentiation of Pluripotent Stem Cells"
    },
    {
      "id": "https://openalex.org/T10407",
      "display_name": "Lipid Rafts and Membrane Dynamics"
    },
    {
      "id": "https://openalex.org/T11786",
      "display_name": "Magnetosome Formation in Prokaryotes"
    },
    {
      "id": "https://openalex.org/T11533",
      "display_name": "Mammalian MAP Kinase Signaling Pathways"
    },
    {
      "id": "https://openalex.org/T10932",
      "display_name": "Metabolic Engineering and Synthetic Biology"
    },
    {
      "id": "https://openalex.org/T13012",
      "display_name": "Metabolism and Functions of Coenzyme Q"
    },
    {
      "id": "https://openalex.org/T10885",
      "display_name": "Microarray Data Analysis and Gene Expression Profiling"
    },
    {
      "id": "https://openalex.org/T14285",
      "display_name": "Microbial Production of Polyglutamic Acid"
    },
    {
      "id": "https://openalex.org/T13736",
      "display_name": "Microbial Transformation of Steroids"
    },
    {
      "id": "https://openalex.org/T10301",
      "display_name": "Mitochondrial Dynamics and Reactive Oxygen Species Regulation"
    },
    {
      "id": "https://openalex.org/T11956",
      "display_name": "Molecular Biology of Steroidogenesis and Disorders"
    },
    {
      "id": "https://openalex.org/T10934",
      "display_name": "Molecular Chaperones in Protein Folding and Disease"
    },
    {
      "id": "https://openalex.org/T11889",
      "display_name": "Molecular Mechanisms and Medical Applications of Ginseng"
    },
    {
      "id": "https://openalex.org/T11305",
      "display_name": "Molecular Mechanisms of Amyloidosis"
    },
    {
      "id": "https://openalex.org/T10422",
      "display_name": "Molecular Mechanisms of Angiogenesis and Vascular Function"
    },
    {
      "id": "https://openalex.org/T10294",
      "display_name": "Molecular Mechanisms of Apoptosis and Cell Death"
    },
    {
      "id": "https://openalex.org/T10724",
      "display_name": "Molecular Mechanisms of Aquaporins in Physiology and Disease"
    },
    {
      "id": "https://openalex.org/T11677",
      "display_name": "Molecular Mechanisms of Cardiac Development and Regeneration"
    },
    {
      "id": "https://openalex.org/T10123",
      "display_name": "Molecular Mechanisms of DNA Damage Response"
    },
    {
      "id": "https://openalex.org/T11237",
      "display_name": "Molecular Mechanisms of Flavonoid Biosynthesis in Plants"
    },
    {
      "id": "https://openalex.org/T12441",
      "display_name": "Molecular Mechanisms of Heme Biosynthesis and Related Disorders"
    },
    {
      "id": "https://openalex.org/T11078",
      "display_name": "Molecular Mechanisms of Inflammasome Activation and Regulation"
    },
    {
      "id": "https://openalex.org/T11075",
      "display_name": "Molecular Mechanisms of Insect Resistance to Xenobiotics"
    },
    {
      "id": "https://openalex.org/T10493",
      "display_name": "Molecular Mechanisms of Ion Channels Regulation"
    },
    {
      "id": "https://openalex.org/T12140",
      "display_name": "Molecular Mechanisms of Kidney Development and Disease"
    },
    {
      "id": "https://openalex.org/T13437",
      "display_name": "Molecular Mechanisms of Metastasis Suppressor Genes"
    },
    {
      "id": "https://openalex.org/T10441",
      "display_name": "Molecular Mechanisms of Muscle Regeneration and Atrophy"
    },
    {
      "id": "https://openalex.org/T11219",
      "display_name": "Molecular Mechanisms of Osteoclast Differentiation and Bone Remodeling"
    },
    {
      "id": "https://openalex.org/T10303",
      "display_name": "Molecular Mechanisms of Photosynthesis and Photoprotection"
    },
    {
      "id": "https://openalex.org/T12789",
      "display_name": "Molecular Mechanisms of Planarian Regeneration"
    },
    {
      "id": "https://openalex.org/T11927",
      "display_name": "Molecular Mechanisms of Pollen Development and Function"
    },
    {
      "id": "https://openalex.org/T10169",
      "display_name": "Molecular Mechanisms of Ras Signaling Pathways"
    },
    {
      "id": "https://openalex.org/T10691",
      "display_name": "Molecular Mechanisms of Retinal Degeneration and Regeneration"
    },
    {
      "id": "https://openalex.org/T11919",
      "display_name": "Molecular Mechanisms of Tooth Development and Morphogenesis"
    },
    {
      "id": "https://openalex.org/T12434",
      "display_name": "Molecular Regulation and Clinical Applications of PDEs"
    },
    {
      "id": "https://openalex.org/T12566",
      "display_name": "Molecular Regulation of Sulfur Metabolism in Plants"
    },
    {
      "id": "https://openalex.org/T14049",
      "display_name": "Molecular Systematics of Gesneriaceae and Allies"
    },
    {
      "id": "https://openalex.org/T10952",
      "display_name": "mTOR Signaling in Growth and Disease"
    },
    {
      "id": "https://openalex.org/T10268",
      "display_name": "Notch Signaling Pathway in Development and Disease"
    },
    {
      "id": "https://openalex.org/T12827",
      "display_name": "Nucleotide Metabolism and Enzyme Regulation"
    },
    {
      "id": "https://openalex.org/T14135",
      "display_name": "Oxidation States in Biochemistry and Medicine"
    },
    {
      "id": "https://openalex.org/T10911",
      "display_name": "Peptide Synthesis and Drug Discovery"
    },
    {
      "id": "https://openalex.org/T11072",
      "display_name": "Peroxisome Proliferator-Activated Receptors"
    },
    {
      "id": "https://openalex.org/T11924",
      "display_name": "Polyamines and Biogenic Amines in Biology and Health"
    },
    {
      "id": "https://openalex.org/T12576",
      "display_name": "Prediction of Peptide-MHC Binding Affinity"
    },
    {
      "id": "https://openalex.org/T12254",
      "display_name": "Prediction of Protein Subcellular Localization"
    },
    {
      "id": "https://openalex.org/T11335",
      "display_name": "Prion Diseases: Causes and Molecular Basis"
    },
    {
      "id": "https://openalex.org/T11124",
      "display_name": "Protein Aggregation and Biopharmaceutical Stability"
    },
    {
      "id": "https://openalex.org/T13157",
      "display_name": "Protein Arginine Methylation in Mammals"
    },
    {
      "id": "https://openalex.org/T11908",
      "display_name": "Protein Binding Specificity in Human Serum Albumin"
    },
    {
      "id": "https://openalex.org/T12867",
      "display_name": "Protein Microarray Technology and Applications"
    },
    {
      "id": "https://openalex.org/T10044",
      "display_name": "Protein Structure Prediction and Analysis"
    },
    {
      "id": "https://openalex.org/T12104",
      "display_name": "Protein Tyrosine Phosphatases in Human Health and Disease"
    },
    {
      "id": "https://openalex.org/T13187",
      "display_name": "Protein-DNA Interaction Dynamics in Living Cells"
    },
    {
      "id": "https://openalex.org/T12756",
      "display_name": "Pyrrolizidine Alkaloids: Toxicity, Metabolism, and Health Implications"
    },
    {
      "id": "https://openalex.org/T11970",
      "display_name": "Real-Time Polymerase Chain Reaction"
    },
    {
      "id": "https://openalex.org/T11663",
      "display_name": "Recombinant Protein Production in Mammalian and Insect Cells"
    },
    {
      "id": "https://openalex.org/T11884",
      "display_name": "Redox Signaling and Oxidative Stress"
    },
    {
      "id": "https://openalex.org/T12835",
      "display_name": "Regulation and Functions of FoxO Transcription Factors"
    },
    {
      "id": "https://openalex.org/T10222",
      "display_name": "Regulation of Chromatin Structure and Function"
    },
    {
      "id": "https://openalex.org/T10604",
      "display_name": "Regulation of RNA Processing and Function"
    },
    {
      "id": "https://openalex.org/T13651",
      "display_name": "Research on Rhodiola rosea and Salidroside"
    },
    {
      "id": "https://openalex.org/T14065",
      "display_name": "Research on Synthetic Phosphoethanolamine and its Effects"
    },
    {
      "id": "https://openalex.org/T10521",
      "display_name": "Ribosome Structure and Translation Mechanisms"
    },
    {
      "id": "https://openalex.org/T11482",
      "display_name": "RNA Methylation and Modification in Gene Expression"
    },
    {
      "id": "https://openalex.org/T10015",
      "display_name": "RNA Sequencing Data Analysis"
    },
    {
      "id": "https://openalex.org/T11339",
      "display_name": "Role of AMP-Activated Protein Kinase in Cellular Metabolism"
    },
    {
      "id": "https://openalex.org/T12412",
      "display_name": "Role of Carbonic Anhydrases in Medicine and Biotechnology"
    },
    {
      "id": "https://openalex.org/T13223",
      "display_name": "Role of CCN Proteins in Signaling Pathways"
    },
    {
      "id": "https://openalex.org/T12187",
      "display_name": "Role of Glutathione in Oxidative Stress Response"
    },
    {
      "id": "https://openalex.org/T11736",
      "display_name": "Role of Histone Deacetylases in Cellular Regulation"
    },
    {
      "id": "https://openalex.org/T11332",
      "display_name": "Role of Nrf2 Signaling in Oxidative Stress Response"
    },
    {
      "id": "https://openalex.org/T11559",
      "display_name": "Role of Retinoic Acid in Biological Processes"
    },
    {
      "id": "https://openalex.org/T13047",
      "display_name": "Role of Sigma Receptors in Cellular Signaling"
    },
    {
      "id": "https://openalex.org/T13426",
      "display_name": "Role of Transcription Factors in Cell Regulation"
    },
    {
      "id": "https://openalex.org/T12030",
      "display_name": "S100 Proteins: Structure, Function, and Pathology"
    },
    {
      "id": "https://openalex.org/T11308",
      "display_name": "Sphingolipid Signalling and Metabolism in Health and Disease"
    },
    {
      "id": "https://openalex.org/T10621",
      "display_name": "Stochasticity in Gene Regulatory Networks"
    },
    {
      "id": "https://openalex.org/T11178",
      "display_name": "Structure and Function of G Protein-Coupled Receptors"
    },
    {
      "id": "https://openalex.org/T11480",
      "display_name": "Structure and Function of Gap Junctions and Connexins"
    },
    {
      "id": "https://openalex.org/T11818",
      "display_name": "Structure and Function of Nicotinic Receptors"
    },
    {
      "id": "https://openalex.org/T11841",
      "display_name": "Structure and Function of the Nuclear Pore Complex"
    },
    {
      "id": "https://openalex.org/T12534",
      "display_name": "Targeted Protein Degradation in Biomedical Research"
    },
    {
      "id": "https://openalex.org/T11501",
      "display_name": "Transforming Growth Factor Beta Signaling Pathway"
    },
    {
      "id": "https://openalex.org/T11041",
      "display_name": "Ubiquitin-Proteasome Proteolytic Pathway"
    },
    {
      "id": "https://openalex.org/T10929",
      "display_name": "Wnt Signaling in Development and Disease"
    }
  ],
  "works_count": 91280,
  "cited_by_count": 2752532,
  "updated_date": "2024-08-26T06:12:46.399281",
  "created_date": "2024-01-23"
}
}

Latest revision as of 21:02, 12 September 2024

{ 

 "OpenAlex": {
   "display_name": "Mechanisms and Applications of RNA Interference",
   "description": "This cluster of papers explores the mechanisms, delivery methods, and therapeutic applications of RNA interference (RNAi) in mammalian cells. It covers topics such as siRNA delivery, gene silencing, non-viral vectors, cell-penetrating peptides, lipid nanoparticles, and the potential of RNAi for gene therapy. The research also delves into the challenges and future directions of RNAi-based therapeutics.",
   "keywords": [
     "RNA Interference",
     "siRNA Delivery",
     "Gene Silencing",
     "Non-viral Vectors",
     "Therapeutic RNAi",
     "Cell-penetrating Peptides",
     "Lipid Nanoparticles",
     "siRNA Therapeutics",
     "Gene Therapy",
     "Nucleic Acid Delivery"
   ],
   "ids": {
     "openalex": "https://openalex.org/T10725",
     "wikipedia": "https://en.wikipedia.org/wiki/RNA_interference"
   },
   "subfield": {
     "id": "https://openalex.org/subfields/1312",
     "display_name": "Molecular Biology"
   },
   "field": {
     "id": "https://openalex.org/fields/13",
     "display_name": "Biochemistry, Genetics and Molecular Biology"
   },
   "domain": {
     "id": "https://openalex.org/domains/1",
     "display_name": "Life Sciences"
   },
   "updated_date": "2024-08-12T05:58:21.955857",
   "created_date": "2024-01-23",
   "type": "topic",
   "oa_id": "T10725",
   "id": "https://openalex.org/T10725"
 }

}

Retrieved from "https://geokb.wikibase.cloud/w/index.php?title=Item_talk:Q167231&oldid=1404340"