Item talk:Q167703: Difference between revisions
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{ | |||
"id": "https://openalex.org/T13991", | |||
"display_name": "Nurr1/CoREST Pathway in Neuroprotection and Inflammation", | |||
"description": "This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis.", | |||
"keywords": [ | |||
"Nurr1", | |||
"NR4A2", | |||
"dopaminergic neurons", | |||
"Parkinson's disease", | |||
"inflammation", | |||
"mitochondrial targeting", | |||
"nuclear receptors", | |||
"neurodegeneration", | |||
"transcriptional regulation", | |||
"apoptosis" | |||
], | |||
id: https://openalex.org/ | "ids": { | ||
"openalex": "https://openalex.org/T13991", | |||
"wikipedia": "https://en.wikipedia.org/wiki/NR4A2" | |||
}, | |||
"subfield": { | |||
"id": "https://openalex.org/subfields/2804", | |||
"display_name": "Cellular and Molecular Neuroscience" | |||
}, | |||
"field": { | |||
"id": "https://openalex.org/fields/28", | |||
"display_name": "Neuroscience" | |||
}, | |||
"domain": { | |||
"id": "https://openalex.org/domains/1", | |||
"display_name": "Life Sciences" | |||
}, | |||
"siblings": [ | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T11406", | |||
id: https://openalex.org/ | "display_name": "Brain Fluid Dynamics and Waste Clearance Mechanisms" | ||
}, | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T13446", | |||
id: https://openalex.org/ | "display_name": "Effects of D-Galactose on Aging and Neurodegeneration" | ||
}, | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T12331", | |||
id: https://openalex.org/ | "display_name": "Genetic Basis of Neuropathies and Related Disorders" | ||
}, | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T12061", | |||
id: https://openalex.org/ | "display_name": "Molecular Mechanisms of Axon Guidance" | ||
}, | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T10949", | |||
id: https://openalex.org/ | "display_name": "Molecular Mechanisms of Neurodegenerative Diseases" | ||
}, | |||
id: https://openalex.org/ | { | ||
"id": "https://openalex.org/T10077", | |||
"display_name": "Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T11601", | |||
"display_name": "Neural Interface Technology" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T10056", | |||
"display_name": "Neurobiological Mechanisms of Drug Addiction and Depression" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T10423", | |||
"display_name": "Neuroscience and Genetics of Drosophila Melanogaster" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T12236", | |||
"display_name": "Optogenetics in Neuroscience and Biophysics Research" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T10814", | |||
"display_name": "Role of Neuropeptides in Physiology and Disease" | |||
}, | |||
{ | |||
"id": "https://openalex.org/T10483", | |||
"display_name": "Roles of Neurotrophins in Nervous System Function" | |||
} | |||
], | |||
"works_count": 15835, | |||
"cited_by_count": 350936, | |||
"updated_date": "2024-08-26T05:27:36.600534", | |||
"created_date": "2024-01-23" | |||
} |
Revision as of 13:54, 30 August 2024
{
"id": "https://openalex.org/T13991", "display_name": "Nurr1/CoREST Pathway in Neuroprotection and Inflammation", "description": "This cluster of papers explores the Nurr1/CoREST pathway and its role in protecting dopaminergic neurons from inflammation-induced death, with implications for neurodegenerative diseases such as Parkinson's. The research covers topics such as mitochondrial targeting, nuclear receptors, transcriptional regulation, and apoptosis.", "keywords": [ "Nurr1", "NR4A2", "dopaminergic neurons", "Parkinson's disease", "inflammation", "mitochondrial targeting", "nuclear receptors", "neurodegeneration", "transcriptional regulation", "apoptosis" ], "ids": { "openalex": "https://openalex.org/T13991", "wikipedia": "https://en.wikipedia.org/wiki/NR4A2" }, "subfield": { "id": "https://openalex.org/subfields/2804", "display_name": "Cellular and Molecular Neuroscience" }, "field": { "id": "https://openalex.org/fields/28", "display_name": "Neuroscience" }, "domain": { "id": "https://openalex.org/domains/1", "display_name": "Life Sciences" }, "siblings": [ { "id": "https://openalex.org/T11406", "display_name": "Brain Fluid Dynamics and Waste Clearance Mechanisms" }, { "id": "https://openalex.org/T13446", "display_name": "Effects of D-Galactose on Aging and Neurodegeneration" }, { "id": "https://openalex.org/T12331", "display_name": "Genetic Basis of Neuropathies and Related Disorders" }, { "id": "https://openalex.org/T12061", "display_name": "Molecular Mechanisms of Axon Guidance" }, { "id": "https://openalex.org/T10949", "display_name": "Molecular Mechanisms of Neurodegenerative Diseases" }, { "id": "https://openalex.org/T10077", "display_name": "Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders" }, { "id": "https://openalex.org/T11601", "display_name": "Neural Interface Technology" }, { "id": "https://openalex.org/T10056", "display_name": "Neurobiological Mechanisms of Drug Addiction and Depression" }, { "id": "https://openalex.org/T10423", "display_name": "Neuroscience and Genetics of Drosophila Melanogaster" }, { "id": "https://openalex.org/T12236", "display_name": "Optogenetics in Neuroscience and Biophysics Research" }, { "id": "https://openalex.org/T10814", "display_name": "Role of Neuropeptides in Physiology and Disease" }, { "id": "https://openalex.org/T10483", "display_name": "Roles of Neurotrophins in Nervous System Function" } ], "works_count": 15835, "cited_by_count": 350936, "updated_date": "2024-08-26T05:27:36.600534", "created_date": "2024-01-23"
}