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OpenAlex: !!python/object/new:pyalex.api.Topic
{
   dictitems:
  "id": "https://openalex.org/T12672",
    cited_by_count: 537941
   "display_name": "Mechanisms of Apoptotic Cell Clearance and Immune Regulation",
    created_date: '2024-01-23'
  "description": "This cluster of papers focuses on the mechanisms and regulation of apoptotic cell clearance, including the role of CD47, phagocytosis, TAM receptors, efferocytosis, and the implications for cancer immunotherapy. It explores the involvement of various molecules and pathways in the recognition and removal of apoptotic cells by phagocytes, shedding light on potential therapeutic targets for immune-related diseases.",
    description: This cluster of papers focuses on the mechanisms and regulation of
  "keywords": [
      apoptotic cell clearance, including the role of CD47, phagocytosis, TAM receptors,
     "CD47",
      efferocytosis, and the implications for cancer immunotherapy. It explores the
    "apoptotic cells",
      involvement of various molecules and pathways in the recognition and removal
    "phagocytosis",
      of apoptotic cells by phagocytes, shedding light on potential therapeutic targets
    "immune regulation",
      for immune-related diseases.
    "clearance mechanisms",
     display_name: Mechanisms of Apoptotic Cell Clearance and Immune Regulation
    "TAM receptors",
     domain:
    "efferocytosis",
      display_name: Life Sciences
    "cancer immunotherapy",
      id: https://openalex.org/domains/1
    "phosphatidylserine",
     field:
     "macrophages"
      display_name: Immunology and Microbiology
  ],
      id: https://openalex.org/fields/24
  "ids": {
     id: https://openalex.org/T12672
    "openalex": "https://openalex.org/T12672",
     ids:
     "wikipedia": "https://en.wikipedia.org/wiki/Apoptotic_cell_clearance"
      openalex: https://openalex.org/T12672
  },
      wikipedia: https://en.wikipedia.org/wiki/Apoptotic_cell_clearance
  "subfield": {
     keywords:
     "id": "https://openalex.org/subfields/2403",
    - CD47
     "display_name": "Immunology"
    - apoptotic cells
  },
     - phagocytosis
  "field": {
    - immune regulation
    "id": "https://openalex.org/fields/24",
    - clearance mechanisms
    "display_name": "Immunology and Microbiology"
    - TAM receptors
  },
    - efferocytosis
  "domain": {
    - cancer immunotherapy
    "id": "https://openalex.org/domains/1",
    - phosphatidylserine
     "display_name": "Life Sciences"
    - macrophages
  },
    siblings:
  "siblings": [
    - display_name: Genetic Basis of Primary Immunodeficiency Disorders
     {
       id: https://openalex.org/T11725
      "id": "https://openalex.org/T11725",
    - display_name: Human T-cell Leukemia Virus Type 1 Infection
      "display_name": "Genetic Basis of Primary Immunodeficiency Disorders"
       id: https://openalex.org/T12159
    },
    - display_name: Immunobiology of Dendritic Cells
    {
       id: https://openalex.org/T10580
       "id": "https://openalex.org/T12159",
    - display_name: Immunogenicity of Biosimilar Therapeutics in Drug Development
      "display_name": "Human T-cell Leukemia Virus Type 1 Infection"
       id: https://openalex.org/T12255
    },
    - display_name: Immunological Mechanisms in Atherosclerosis Development
    {
       id: https://openalex.org/T12955
       "id": "https://openalex.org/T10580",
    - display_name: Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface
      "display_name": "Immunobiology of Dendritic Cells"
       id: https://openalex.org/T11510
    },
    - display_name: Immunological Responses in Aquatic Organisms
    {
       id: https://openalex.org/T10506
       "id": "https://openalex.org/T12255",
    - display_name: Immunotoxicology in Toxicologic Pathology Research
      "display_name": "Immunogenicity of Biosimilar Therapeutics in Drug Development"
       id: https://openalex.org/T14072
    },
    - display_name: Immunotoxin Therapy for Cancer Treatment
    {
       id: https://openalex.org/T12477
       "id": "https://openalex.org/T12955",
    - display_name: Innate Immune Recognition and Signaling Pathways
      "display_name": "Immunological Mechanisms in Atherosclerosis Development"
       id: https://openalex.org/T10371
    },
    - display_name: Innate Immunity to Viral Infection
    {
       id: https://openalex.org/T11668
       "id": "https://openalex.org/T11510",
    - display_name: Innate Lymphoid Cells in Immunity
      "display_name": "Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface"
       id: https://openalex.org/T12528
    },
    - display_name: Invertebrate Immunity and Host Defense Mechanisms
    {
       id: https://openalex.org/T11403
       "id": "https://openalex.org/T10506",
    - display_name: Macrophage Activation and Polarization
      "display_name": "Immunological Responses in Aquatic Organisms"
       id: https://openalex.org/T11313
    },
    - display_name: Natural Killer Cells in Immunity
    {
       id: https://openalex.org/T11020
       "id": "https://openalex.org/T14072",
    - display_name: Reciprocal Development of TH17 and Treg Cells
      "display_name": "Immunotoxicology in Toxicologic Pathology Research"
       id: https://openalex.org/T10469
    },
    - display_name: Regulatory T Cell Development and Function
    {
       id: https://openalex.org/T10031
       "id": "https://openalex.org/T12477",
    - display_name: Role of Complement System in Immune Response
      "display_name": "Immunotoxin Therapy for Cancer Treatment"
       id: https://openalex.org/T10993
    },
    - display_name: Role of Galectins in Immunity and Disease
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       id: https://openalex.org/T12387
       "id": "https://openalex.org/T10371",
    - display_name: Role of Macrophage Migration Inhibitory Factor
      "display_name": "Innate Immune Recognition and Signaling Pathways"
       id: https://openalex.org/T13254
    },
    - display_name: Role of Mast Cells in Immunoregulation and Disease
    {
       id: https://openalex.org/T11346
       "id": "https://openalex.org/T11668",
    - display_name: Role of Neutrophil Extracellular Traps in Immunity
      "display_name": "Innate Immunity to Viral Infection"
       id: https://openalex.org/T11597
    },
    - display_name: Role of Pentraxins in Innate Immunity and Inflammation
    {
       id: https://openalex.org/T14245
       "id": "https://openalex.org/T12528",
    - display_name: Role of TREM-1 and Endocan in Inflammation
      "display_name": "Innate Lymphoid Cells in Immunity"
       id: https://openalex.org/T14165
    },
    - display_name: Trained Immunity in Health and Disease
    {
      id: https://openalex.org/T13410
       "id": "https://openalex.org/T11403",
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      "display_name": "Invertebrate Immunity and Host Defense Mechanisms"
      display_name: Immunology
    },
      id: https://openalex.org/subfields/2403
    {
    updated_date: '2024-05-20T05:13:29.155971'
       "id": "https://openalex.org/T11313",
    works_count: 22674
      "display_name": "Macrophage Activation and Polarization"
    },
    {
       "id": "https://openalex.org/T11020",
      "display_name": "Natural Killer Cells in Immunity"
    },
    {
       "id": "https://openalex.org/T10469",
      "display_name": "Reciprocal Development of TH17 and Treg Cells"
    },
    {
       "id": "https://openalex.org/T10031",
      "display_name": "Regulatory T Cell Development and Function"
    },
    {
       "id": "https://openalex.org/T10993",
      "display_name": "Role of Complement System in Immune Response"
    },
    {
       "id": "https://openalex.org/T12387",
      "display_name": "Role of Galectins in Immunity and Disease"
    },
    {
       "id": "https://openalex.org/T13254",
      "display_name": "Role of Macrophage Migration Inhibitory Factor"
    },
    {
       "id": "https://openalex.org/T11346",
      "display_name": "Role of Mast Cells in Immunoregulation and Disease"
    },
    {
       "id": "https://openalex.org/T11597",
      "display_name": "Role of Neutrophil Extracellular Traps in Immunity"
    },
    {
       "id": "https://openalex.org/T14245",
      "display_name": "Role of Pentraxins in Innate Immunity and Inflammation"
    },
    {
       "id": "https://openalex.org/T14165",
      "display_name": "Role of TREM-1 and Endocan in Inflammation"
    },
    {
       "id": "https://openalex.org/T13410",
      "display_name": "Trained Immunity in Health and Disease"
    }
  ],
  "works_count": 23176,
  "cited_by_count": 591668,
  "updated_date": "2024-08-26T05:18:52.958159",
  "created_date": "2024-01-23"
}

Revision as of 13:26, 30 August 2024

{

 "id": "https://openalex.org/T12672",
 "display_name": "Mechanisms of Apoptotic Cell Clearance and Immune Regulation",
 "description": "This cluster of papers focuses on the mechanisms and regulation of apoptotic cell clearance, including the role of CD47, phagocytosis, TAM receptors, efferocytosis, and the implications for cancer immunotherapy. It explores the involvement of various molecules and pathways in the recognition and removal of apoptotic cells by phagocytes, shedding light on potential therapeutic targets for immune-related diseases.",
 "keywords": [
   "CD47",
   "apoptotic cells",
   "phagocytosis",
   "immune regulation",
   "clearance mechanisms",
   "TAM receptors",
   "efferocytosis",
   "cancer immunotherapy",
   "phosphatidylserine",
   "macrophages"
 ],
 "ids": {
   "openalex": "https://openalex.org/T12672",
   "wikipedia": "https://en.wikipedia.org/wiki/Apoptotic_cell_clearance"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/2403",
   "display_name": "Immunology"
 },
 "field": {
   "id": "https://openalex.org/fields/24",
   "display_name": "Immunology and Microbiology"
 },
 "domain": {
   "id": "https://openalex.org/domains/1",
   "display_name": "Life Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T11725",
     "display_name": "Genetic Basis of Primary Immunodeficiency Disorders"
   },
   {
     "id": "https://openalex.org/T12159",
     "display_name": "Human T-cell Leukemia Virus Type 1 Infection"
   },
   {
     "id": "https://openalex.org/T10580",
     "display_name": "Immunobiology of Dendritic Cells"
   },
   {
     "id": "https://openalex.org/T12255",
     "display_name": "Immunogenicity of Biosimilar Therapeutics in Drug Development"
   },
   {
     "id": "https://openalex.org/T12955",
     "display_name": "Immunological Mechanisms in Atherosclerosis Development"
   },
   {
     "id": "https://openalex.org/T11510",
     "display_name": "Immunological Mechanisms in Pregnancy and Fetal-Maternal Interface"
   },
   {
     "id": "https://openalex.org/T10506",
     "display_name": "Immunological Responses in Aquatic Organisms"
   },
   {
     "id": "https://openalex.org/T14072",
     "display_name": "Immunotoxicology in Toxicologic Pathology Research"
   },
   {
     "id": "https://openalex.org/T12477",
     "display_name": "Immunotoxin Therapy for Cancer Treatment"
   },
   {
     "id": "https://openalex.org/T10371",
     "display_name": "Innate Immune Recognition and Signaling Pathways"
   },
   {
     "id": "https://openalex.org/T11668",
     "display_name": "Innate Immunity to Viral Infection"
   },
   {
     "id": "https://openalex.org/T12528",
     "display_name": "Innate Lymphoid Cells in Immunity"
   },
   {
     "id": "https://openalex.org/T11403",
     "display_name": "Invertebrate Immunity and Host Defense Mechanisms"
   },
   {
     "id": "https://openalex.org/T11313",
     "display_name": "Macrophage Activation and Polarization"
   },
   {
     "id": "https://openalex.org/T11020",
     "display_name": "Natural Killer Cells in Immunity"
   },
   {
     "id": "https://openalex.org/T10469",
     "display_name": "Reciprocal Development of TH17 and Treg Cells"
   },
   {
     "id": "https://openalex.org/T10031",
     "display_name": "Regulatory T Cell Development and Function"
   },
   {
     "id": "https://openalex.org/T10993",
     "display_name": "Role of Complement System in Immune Response"
   },
   {
     "id": "https://openalex.org/T12387",
     "display_name": "Role of Galectins in Immunity and Disease"
   },
   {
     "id": "https://openalex.org/T13254",
     "display_name": "Role of Macrophage Migration Inhibitory Factor"
   },
   {
     "id": "https://openalex.org/T11346",
     "display_name": "Role of Mast Cells in Immunoregulation and Disease"
   },
   {
     "id": "https://openalex.org/T11597",
     "display_name": "Role of Neutrophil Extracellular Traps in Immunity"
   },
   {
     "id": "https://openalex.org/T14245",
     "display_name": "Role of Pentraxins in Innate Immunity and Inflammation"
   },
   {
     "id": "https://openalex.org/T14165",
     "display_name": "Role of TREM-1 and Endocan in Inflammation"
   },
   {
     "id": "https://openalex.org/T13410",
     "display_name": "Trained Immunity in Health and Disease"
   }
 ],
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 "cited_by_count": 591668,
 "updated_date": "2024-08-26T05:18:52.958159",
 "created_date": "2024-01-23"

}