Item talk:Q138692

orcid:

 Biography: null
 Credit Name: Martin Flajnik
 Emails: []
 Family Name: Flajnik
 Fundings: []
 Name: Martin Francis
 Other Names:
 - Flajnik MF
 Research Tags (keywords): []
 Works:
 - journal title: Proceedings of the National Academy of Sciences
   organization: null
   organization-address: 
   publication-date: 01/2024
   title: The immunoglobulin J chain is an evolutionarily co-opted chemokine
   type: journal-article
   url: https://doi.org/10.1073/pnas.2318995121
 - journal title: Immunogenetics
   organization: null
   organization-address: 
   publication-date: 12/2023
   title: Genomic view of the origins of cell-mediated immunity
   type: journal-article
   url: https://doi.org/10.1007/s00251-023-01319-3
 - journal title: The Journal of Immunology
   organization: null
   organization-address: 
   publication-date: 09/2023
   title: An Ancient MHC-Linked Gene Encodes a Nonrearranging Shark Antibody, UrIg,
     Convergent with IgG
   type: journal-article
   url: https://doi.org/10.4049/jimmunol.2300361
 - journal title: Zebrafish
   organization: null
   organization-address: 
   publication-date: 12/2021
   title: 'From IgZ to IgT: A Call for a Common Nomenclature for Immunoglobulin Heavy
     Chain Genes of Ray-Finned Fish'
   type: journal-article
   url: https://doi.org/10.1089/zeb.2021.0071
 - journal title: European Journal of Immunology
   organization: null
   organization-address: 
   publication-date: 11/2021
   title: "Identification of the Fc\u2010alpha/mu receptor in Xenopus provides insight\
     \ into the emergence of the poly\u2010Ig receptor (pIgR) and mucosal Ig transport"
   type: journal-article
   url: https://doi.org/10.1002/eji.202149383
 - journal title: The Journal of Immunology
   organization: null
   organization-address: 
   publication-date: 08/2021
   title: A Highly Complex, MHC-Linked, 350 Million-Year-Old Shark Nonclassical Class
     I Lineage
   type: journal-article
   url: https://doi.org/10.4049/jimmunol.2000851
 - journal title: Immunogenetics
   organization: null
   organization-address: 
   publication-date: 08/2021
   title: Analysis of shark NCR3 family genes reveals primordial features of vertebrate
     NKp30
   type: journal-article
   url: https://doi.org/10.1007/s00251-021-01209-6
 - journal title: The Journal of Immunology
   organization: null
   organization-address: 
   publication-date: 02/2020
   title: An Ancient, MHC-Linked, Nonclassical Class I Lineage in Cartilaginous Fish
   type: journal-article
   url: https://doi.org/10.4049/jimmunol.1901025
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2015
   title: CXCL13 responsiveness but not CXCR5 expression by late transitional B cells
     initiates splenic white pulp formation.
   type: journal-article
   url: http://europepmc.org/abstract/med/25662995
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/2014
   title: Re-evaluation of the immunological Big Bang.
   type: journal-article
   url: http://europepmc.org/abstract/med/25517375
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2014
   title: 'Putting J chain back on the map: how might its expression define plasma
     cell development?'
   type: journal-article
   url: http://europepmc.org/abstract/med/25240020
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2014
   title: Venkatesh et al. reply.
   type: journal-article
   url: http://europepmc.org/abstract/med/25008535
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/2014
   title: The structural analysis of shark IgNAR antibodies reveals evolutionary
     principles of immunoglobulins.
   type: journal-article
   url: http://europepmc.org/abstract/med/24830426
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/2014
   title: Elephant shark genome provides unique insights into gnathostome evolution.
   type: journal-article
   url: http://europepmc.org/abstract/med/24402279
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/2013
   title: Noncoordinate expression of J-chain and Blimp-1 define nurse shark plasma
     cell populations during ontogeny.
   type: journal-article
   url: http://europepmc.org/abstract/med/23897025
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2012
   title: Humoral response of captive zebra sharks Stegostoma fasciatum to salivary
     gland proteins of the leech Branchellion torpedinis.
   type: journal-article
   url: http://europepmc.org/abstract/med/22963935
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/2012
   title: 'Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification
     of a new B7 family member, B7H7, and of B7s historical relationship with the
     MHC.'
   type: journal-article
   url: http://europepmc.org/abstract/med/22488247
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/2012
   title: Characterization of the immunoglobulin repertoire of the spiny dogfish
     (Squalus acanthias).
   type: journal-article
   url: http://europepmc.org/abstract/med/22040740
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2012
   title: Shark class II invariant chain reveals ancient conserved relationships
     with cathepsins and MHC class II.
   type: journal-article
   url: http://europepmc.org/abstract/med/21996610
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/2012
   title: "Comparative genomic analysis of the proteasome \u03B25t subunit gene:\
     \ implications for the origin and evolution of thymoproteasomes."
   type: journal-article
   url: http://europepmc.org/abstract/med/21748441
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2011
   title: Isolation and characterisation of Ebolavirus-specific recombinant antibody
     fragments from murine and shark immune libraries.
   type: journal-article
   url: http://europepmc.org/abstract/med/21752470
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2011
   title: The multiple shark Ig H chain genes rearrange and hypermutate autonomously.
   type: journal-article
   url: http://europepmc.org/abstract/med/21804022
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/2011
   title: 'A case of convergence: why did a simple alternative to canonical antibodies
     arise in sharks and camels?'
   type: journal-article
   url: http://europepmc.org/abstract/med/21829328
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2011
   title: 'Immunology: the origin of sweetbreads in lampreys?'
   type: journal-article
   url: http://europepmc.org/abstract/med/21419986
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2011
   title: "Primordial linkage of \u03B22-microglobulin to the MHC."
   type: journal-article
   url: http://europepmc.org/abstract/med/21321107
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2010
   title: All GOD's creatures got dedicated mucosal immunity.
   type: journal-article
   url: http://europepmc.org/abstract/med/20720582
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/2010
   title: "The dynamic TCR\u03B4: TCR\u03B4 chains in the amphibian Xenopus tropicalis\
     \ utilize antibody-like V genes."
   type: journal-article
   url: http://europepmc.org/abstract/med/20486124
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2010
   title: A structural basis for antigen recognition by the T cell-like lymphocytes
     of sea lamprey.
   type: journal-article
   url: http://europepmc.org/abstract/med/20616002
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/2010
   title: Evolutionarily conserved TCR binding sites, identification of T cells in
     primary lymphoid tissues, and surprising trans-rearrangements in nurse shark.
   type: journal-article
   url: http://europepmc.org/abstract/med/20488795
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/2010
   title: 'Origin and evolution of the adaptive immune system: genetic events and
     selective pressures.'
   type: journal-article
   url: http://europepmc.org/abstract/med/19997068
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2010'
   title: Emergence of the acute-phase protein hemopexin in jawed vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/20884052
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/2009
   title: High-affinity lamprey VLRA and VLRB monoclonal antibodies.
   type: journal-article
   url: http://europepmc.org/abstract/med/19625627
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2009'
   title: The generation and selection of single-domain, v region libraries from
     nurse sharks.
   type: journal-article
   url: http://europepmc.org/abstract/med/19554288
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/2008
   title: Immunoglobulin heavy chain exclusion in the shark.
   type: journal-article
   url: http://europepmc.org/abstract/med/18578572
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/2008
   title: 'Evolutionarily conserved and divergent regions of the autoimmune regulator
     (Aire) gene: a comparative analysis.'
   type: journal-article
   url: http://europepmc.org/abstract/med/18214467
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/2007
   title: Localization and differential expression of activation-induced cytidine
     deaminase in the amphibian Xenopus upon antigen stimulation and during early
     development.
   type: journal-article
   url: http://europepmc.org/abstract/med/17982068
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2007
   title: Four primordial immunoglobulin light chain isotypes, including lambda and
     kappa, identified in the most primitive living jawed vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/17899545
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2007
   title: 'Immunogenetics: alternative strategies in adaptive immunity and the rise
     of comparative immunogenomics.'
   type: journal-article
   url: http://europepmc.org/abstract/med/17719759
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2007
   title: 'Maturation of shark single-domain (IgNAR) antibodies: evidence for induced-fit
     binding.'
   type: journal-article
   url: http://europepmc.org/abstract/med/17258766
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2006
   title: IgD, like IgM, is a primordial immunoglobulin class perpetuated in most
     jawed vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/16818885
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/2006
   title: The plasticity of immunoglobulin gene systems in evolution.
   type: journal-article
   url: http://europepmc.org/abstract/med/16623761
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2006
   title: 'An evolutionarily mobile antigen receptor variable region gene: doubly
     rearranging NAR-TcR genes in sharks.'
   type: journal-article
   url: http://europepmc.org/abstract/med/16549799
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2006
   title: Ancestral organization of the MHC revealed in the amphibian Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/16517736
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/2006
   title: First molecular and biochemical analysis of in vivo affinity maturation
     in an ectothermic vertebrate.
   type: journal-article
   url: http://europepmc.org/abstract/med/16446445
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2006'
   title: Antibody repertoire development in cartilaginous fish.
   type: journal-article
   url: http://europepmc.org/abstract/med/16146649
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2006'
   title: Construction of a nurse shark (Ginglymostoma cirratum) bacterial artificial
     chromosome (BAC) library and a preliminary genome survey.
   type: journal-article
   url: http://europepmc.org/abstract/med/16672057
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2006'
   title: Histology and immunology of the placenta in the Atlantic sharpnose shark,
     Rhizoprionodon terraenovae.
   type: journal-article
   url: http://europepmc.org/abstract/med/16503351
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/2005
   title: Somatic hypermutation and junctional diversification at Ig heavy chain
     loci in the nurse shark.
   type: journal-article
   url: http://europepmc.org/abstract/med/16339548
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2005
   title: 'Shark immunity bites back: affinity maturation and memory response in
     the nurse shark, Ginglymostoma cirratum.'
   type: journal-article
   url: http://europepmc.org/abstract/med/15688348
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2005
   title: The last flag unfurled? A new immunoglobulin isotype in fish expressed
     in early development.
   type: journal-article
   url: http://europepmc.org/abstract/med/15716968
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2005'
   title: Cloning and characterization of Xenopus beta2-microglobulin.
   type: journal-article
   url: http://europepmc.org/abstract/med/15854684
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2005'
   title: Immunoglobulins in the eggs of the nurse shark, Ginglymostoma cirratum.
   type: journal-article
   url: http://europepmc.org/abstract/med/15707663
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/2004
   title: 'Evolution of innate and adaptive immunity: can we draw a line?'
   type: journal-article
   url: http://europepmc.org/abstract/med/15530832
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/2004
   title: Shark Ig light chain junctions are as diverse as in heavy chains.
   type: journal-article
   url: http://europepmc.org/abstract/med/15494507
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2004
   title: Homologs of CD83 from elasmobranch and teleost fish.
   type: journal-article
   url: http://europepmc.org/abstract/med/15383588
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2004
   title: Crystal structure of a shark single-domain antibody V region in complex
     with lysozyme.
   type: journal-article
   url: http://europepmc.org/abstract/med/15319492
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2004
   title: 'Immunology: another manifestation of GOD.'
   type: journal-article
   url: http://europepmc.org/abstract/med/15241401
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2004
   title: Unprecedented multiplicity of Ig transmembrane and secretory mRNA forms
     in the cartilaginous fish.
   type: journal-article
   url: http://europepmc.org/abstract/med/15240702
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/2004
   title: Diversity and repertoire of IgW and IgM VH families in the newborn nurse
     shark.
   type: journal-article
   url: http://europepmc.org/abstract/med/15132758
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/2003
   title: Terminal deoxynucleotidyl transferases from elasmobranchs reveal structural
     conservation within vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/14579105
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/2003
   title: 'Two highly divergent ancient allelic lineages of the transporter associated
     with antigen processing (TAP) gene in Xenopus: further evidence for co-evolution
     among MHC class I region genes.'
   type: journal-article
   url: http://europepmc.org/abstract/med/14579270
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2003
   title: Molecular cloning of C4 gene and identification of the class III complement
     region in the shark MHC.
   type: journal-article
   url: http://europepmc.org/abstract/med/12928394
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2003
   title: Selection and characterization of naturally occurring single-domain (IgNAR)
     antibody fragments from immunized sharks by phage display.
   type: journal-article
   url: http://europepmc.org/abstract/med/12909128
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/2003
   title: 'J chain in the nurse shark: implications for function in a lower vertebrate.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12794129
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2002
   title: 'Structural analysis, selection, and ontogeny of the shark new antigen
     receptor (IgNAR): identification of a new locus preferentially expressed in
     early development.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12389098
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/2002
   title: 'Xenopus class II A genes: studies of genetics, polymorphism, and expression.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12206837
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2002
   title: 'Comparative analyses of immunoglobulin genes: surprises and portents.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12209137
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/2002
   title: 'The development of primary and secondary lymphoid tissues in the nurse
     shark Ginglymostoma cirratum: B-cell zones precede dendritic cell immigration
     and T-cell zone formation during ontogeny of the spleen.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12121433
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2002
   title: 'The leukocyte common antigen (CD45) of the Pacific hagfish, Eptatretus
     stoutii: implications for the primordial function of CD45.'
   type: journal-article
   url: http://europepmc.org/abstract/med/12136341
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/2002
   title: Hypermutation in shark immunoglobulin light chain genes results in contiguous
     substitutions.
   type: journal-article
   url: http://europepmc.org/abstract/med/11970880
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/2002
   title: 'Proteasome, transporter associated with antigen processing, and class
     I genes in the nurse shark Ginglymostoma cirratum: evidence for a stable class
     I region and MHC haplotype lineages.'
   type: journal-article
   url: http://europepmc.org/abstract/med/11777971
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/2001
   title: 'Comparative genomics of the MHC: glimpses into the evolution of the adaptive
     immune system.'
   type: journal-article
   url: http://europepmc.org/abstract/med/11567626
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/2001
   title: Decreased frequency of somatic hypermutation and impaired affinity maturation
     but intact germinal center formation in mice expressing antisense RNA to DNA
     polymerase zeta.
   type: journal-article
   url: http://europepmc.org/abstract/med/11418667
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/2001
   title: The translesion DNA polymerase zeta plays a major role in Ig and bcl-6
     somatic hypermutation.
   type: journal-article
   url: http://europepmc.org/abstract/med/11371365
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/2001
   title: A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ
     is preferentially expressed in early development and is convergent with mammalian
     IgG.
   type: journal-article
   url: http://europepmc.org/abstract/med/11172027
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/2001
   title: Evolution and the molecular basis of somatic hypermutation of antigen receptor
     genes.
   type: journal-article
   url: http://europepmc.org/abstract/med/11205333
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/2000
   title: Rearrangement of immunoglobulin genes in shark germ cells.
   type: journal-article
   url: http://europepmc.org/abstract/med/10811858
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/2000
   title: Primitive synteny of vertebrate major histocompatibility complex class
     I and class II genes.
   type: journal-article
   url: http://europepmc.org/abstract/med/10781076
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/2000
   title: Trans-species polymorphism of the major histocompatibility complex-encoded
     proteasome subunit LMP7 in an amphibian genus, Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/10752627
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2000'
   title: Early and natural antibodies in non-mammalian vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/11125480
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '2000'
   title: The immune system of cartilaginous fish.
   type: journal-article
   url: http://europepmc.org/abstract/med/10793481
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/1999
   title: Isolation of transporter associated with antigen processing genes, TAP1
     and TAP2, from the horned shark Heterodontus francisci.
   type: journal-article
   url: http://europepmc.org/abstract/med/10501841
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 10/1999
   title: Two ancient allelic lineages at the single classical class I locus in the
     Xenopus MHC.
   type: journal-article
   url: http://europepmc.org/abstract/med/10490981
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1999
   title: 'Mutational pattern of the nurse shark antigen receptor gene (NAR) is similar
     to that of mammalian Ig genes and to spontaneous mutations in evolution: the
     translesion synthesis model of somatic hypermutation.'
   type: journal-article
   url: http://europepmc.org/abstract/med/10330287
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/1999
   title: Identification and genetic mapping of Xenopus TAP2 genes.
   type: journal-article
   url: http://europepmc.org/abstract/med/9914331
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/1999
   title: Insight into the primordial MHC from studies in ectothermic vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/10319251
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/1998
   title: Churchill and the immune system of ectothermic vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/9914898
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1998
   title: 'Somatic hypermutation of the new antigen receptor gene (NAR) in the nurse
     shark does not generate the repertoire: possible role in antigen-driven reactions
     in the absence of germinal centers.'
   type: journal-article
   url: http://europepmc.org/abstract/med/9826702
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/1998
   title: 'Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular
     convergence of NAR and unusual mammalian immunoglobulins.'
   type: journal-article
   url: http://europepmc.org/abstract/med/9751746
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/1998
   title: Evolution of somatic hypermutation and gene conversion in adaptive immunity.
   type: journal-article
   url: http://europepmc.org/abstract/med/9602348
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/1998
   title: 'Expression of MHC class Ia and class Ib during ontogeny: high expression
     in epithelia and coregulation of class Ia and lmp7 genes.'
   type: journal-article
   url: http://europepmc.org/abstract/med/9510188
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1998'
   title: 'Somatic mutation in ectothermic vertebrates: musings on selection and
     origins.'
   type: journal-article
   url: http://europepmc.org/abstract/med/9479856
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/1997
   title: Identification of class I genes in cartilaginous fish, the most ancient
     group of vertebrates displaying an adaptive immune response.
   type: journal-article
   url: http://europepmc.org/abstract/med/9550410
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/1997
   title: 'Evolution of proteasome subunits delta and LMP2: complementary DNA cloning
     and linkage analysis with MHC in lower vertebrates.'
   type: journal-article
   url: http://europepmc.org/abstract/med/9218589
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1997
   title: Major histocompatibility complex gene mapping in the amphibian Xenopus
     implies a primordial organization.
   type: journal-article
   url: http://europepmc.org/abstract/med/9159152
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/1997
   title: IgM-mediated opsonization and cytotoxicity in the shark.
   type: journal-article
   url: http://europepmc.org/abstract/med/9021918
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1997'
   title: Involvement of thyroid hormones in the expression of MHC class I antigens
     during ontogeny in Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/9587714
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1996
   title: The immune system of ectothermic vertebrates.
   type: journal-article
   url: http://europepmc.org/abstract/med/8988858
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/1996
   title: Isolation of low molecular mass polypeptide complementary DNA clones from
     primitive vertebrates. Implications for the origin of MHC class I-restricted
     antigen presentation.
   type: journal-article
   url: http://europepmc.org/abstract/med/8666794
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/1996
   title: 'Origin and evolution of the class I gene family: why are some of the mammalian
     class I genes encoded outside the major histocompatibility complex?'
   type: journal-article
   url: http://europepmc.org/abstract/med/8876055
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1996
   title: 'A novel "chimeric" antibody class in cartilaginous fish: IgM may not be
     the primordial immunoglobulin.'
   type: journal-article
   url: http://europepmc.org/abstract/med/8647177
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/1996
   title: Isolation and characterization of a cDNA encoding a Xenopus 70-kDa heat
     shock cognate protein, Hsc70.I.
   type: journal-article
   url: http://europepmc.org/abstract/med/8925437
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/1995
   title: Isolation of Xenopus LMP-7 homologues. Striking allelic diversity and linkage
     to MHC.
   type: journal-article
   url: http://europepmc.org/abstract/med/7636247
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/1995
   title: A new antigen receptor gene family that undergoes rearrangement and extensive
     somatic diversification in sharks.
   type: journal-article
   url: http://europepmc.org/abstract/med/7877689
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 03/1995
   title: 'Evolution of the major histocompatibility complex: a current overview.'
   type: journal-article
   url: http://europepmc.org/abstract/med/7551974
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1995'
   title: Duplication of the MHC-linked Xenopus complement factor B gene.
   type: journal-article
   url: http://europepmc.org/abstract/med/7642231
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1995'
   title: Evolution and developmental regulation of the major histocompatibility
     complex.
   type: journal-article
   url: http://europepmc.org/abstract/med/8519422
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1995'
   title: Exon-intron organization of Xenopus MHC class II beta chain genes.
   type: journal-article
   url: http://europepmc.org/abstract/med/7590971
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/1994
   title: Structural conservation of hypervariable regions in immunoglobulins evolution.
   type: journal-article
   url: http://europepmc.org/abstract/med/7773781
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1994
   title: Isolation of the Xenopus complement factor B complementary DNA and linkage
     of the gene to the frog MHC.
   type: journal-article
   url: http://europepmc.org/abstract/med/7963526
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/1994
   title: Advances in immunology.
   type: journal-article
   url: http://europepmc.org/abstract/med/7980494
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1994'
   title: Hsp70 genes are linked to the Xenopus major histocompatibility complex.
   type: journal-article
   url: http://europepmc.org/abstract/med/7901155
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1994'
   title: 'Primitive vertebrate immunity: what is the evolutionary derivative of
     molecules that define the adaptive immune system?'
   type: journal-article
   url: http://europepmc.org/abstract/med/7768153
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1993
   title: 'A novel type of class I gene organization in vertebrates: a large family
     of non-MHC-linked class I genes is expressed at the RNA level in the amphibian
     Xenopus.'
   type: journal-article
   url: http://europepmc.org/abstract/med/8223448
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1993
   title: Isolation of a classical MHC class I cDNA from an amphibian. Evidence for
     only one class I locus in the Xenopus MHC.
   type: journal-article
   url: http://europepmc.org/abstract/med/8228232
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 11/1993
   title: 'Isolation of a shark immunoglobulin light chain cDNA clone encoding a
     protein resembling mammalian kappa light chains: implications for the evolution
     of light chains.'
   type: journal-article
   url: http://europepmc.org/abstract/med/8248152
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/1993
   title: 'The evolutionary origin of the major histocompatibility complex: polymorphism
     of class II alpha chain genes in the cartilaginous fish.'
   type: journal-article
   url: http://europepmc.org/abstract/med/8370399
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 04/1993
   title: 'Evolution of the MHC: isolation of class II beta-chain cDNA clones from
     the amphibian Xenopus laevis.'
   type: journal-article
   url: http://europepmc.org/abstract/med/8454860
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1993'
   title: MHC restriction of T-cell proliferative responses in Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/7505753
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/1992
   title: Nucleotide sequence of a nurse shark immunoglobulin heavy chain cDNA clone.
   type: journal-article
   url: http://europepmc.org/abstract/med/1495502
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 08/1992
   title: 'Evolution of the major histocompatibility complex: isolation of class
     II A cDNA clones from the cartilaginous fish.'
   type: journal-article
   url: http://europepmc.org/abstract/med/1495958
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 01/1991
   title: 'Evolution of the major histocompatibility complex: molecular cloning of
     major histocompatibility complex class I from the amphibian Xenopus.'
   type: journal-article
   url: http://europepmc.org/abstract/med/1703301
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1991'
   title: Which came first, MHC class I or class II?
   type: journal-article
   url: http://europepmc.org/abstract/med/2050387
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1990
   title: 'Evolution of the MHC: antigenicity and unusual tissue distribution of
     Xenopus (frog) class II molecules.'
   type: journal-article
   url: http://europepmc.org/abstract/med/2366760
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/1990
   title: The major histocompatibility complex of frogs.
   type: journal-article
   url: http://europepmc.org/abstract/med/2180810
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1990'
   title: Expression of MHC class II antigens during Xenopus development.
   type: journal-article
   url: http://europepmc.org/abstract/med/2136209
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 02/1989
   title: Experimental analysis of ventral blood island hematopoiesis in Xenopus
     embryonic chimeras.
   type: journal-article
   url: http://europepmc.org/abstract/med/2463944
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1989'
   title: The immune system of Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/2653371
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/1988
   title: MHC class I antigens as surface markers of adult erythrocytes during the
     metamorphosis of Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/3384174
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1987'
   title: Changes in the immune system during metamorphosis of Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/25291685
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 12/1986
   title: Major histocompatibility complex-encoded class I molecules are absent in
     immunologically competent Xenopus before metamorphosis.
   type: journal-article
   url: http://europepmc.org/abstract/med/3537126
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 09/1985
   title: A third immunoglobulin class in amphibians.
   type: journal-article
   url: http://europepmc.org/abstract/med/3926893
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 06/1985
   title: 'Immune responses of thymus/lymphocyte embryonic chimeras: studies on tolerance
     and major histocompatibility complex restriction in Xenopus.'
   type: journal-article
   url: http://europepmc.org/abstract/med/3874068
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1985
   title: Xenopus MHC class II molecules. I. Identification and structural characterization.
   type: journal-article
   url: http://europepmc.org/abstract/med/3156930
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 05/1985
   title: Xenopus MHC class II molecules. II. Polymorphism as determined by two-dimensional
     gel electrophoresis.
   type: journal-article
   url: http://europepmc.org/abstract/med/3980992
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1985'
   title: Studies on the Xenopus major histocompatibility complex.
   type: journal-article
   url: http://europepmc.org/abstract/med/4085679
 - journal title: null
   organization: null
   organization-address: 
   publication-date: 07/1984
   title: A flow cytometric analysis of the embryonic origin of lymphocytes in diploid/triploid
     chimeric Xenopus laevis.
   type: journal-article
   url: http://europepmc.org/abstract/med/6734938
 - journal title: null
   organization: null
   organization-address: 
   publication-date: '1984'
   title: Identification of class I major histocompatibility complex encoded molecules
     in the amphibian Xenopus.
   type: journal-article
   url: http://europepmc.org/abstract/med/6490110