Item talk:Q166962: Difference between revisions

From geokb
(Added OpenAlex topic data)
 
No edit summary
Line 1: Line 1:
OpenAlex: !!python/object/new:pyalex.api.Topic
{
   dictitems:
  "id": "https://openalex.org/T12023",
    cited_by_count: 855297
   "display_name": "Cholinesterase Inhibitors in Neurodegenerative Diseases",
    created_date: '2024-01-23'
  "description": "This cluster of papers focuses on the pharmacology and toxicology of cholinesterase inhibitors, particularly acetylcholinesterase and butyrylcholinesterase, in the context of neurodegenerative diseases such as Alzheimer's. It explores the development of multi-target-directed ligands, novel drug therapies, and the implications for cognitive deficits. The research also delves into the structure, function, and regulation of cholinesterases, as well as their potential roles in neuroprotection and neurorestoration.",
    description: This cluster of papers focuses on the pharmacology and toxicology
  "keywords": [
      of cholinesterase inhibitors, particularly acetylcholinesterase and butyrylcholinesterase,
     "Cholinesterase Inhibitors",
      in the context of neurodegenerative diseases such as Alzheimer's. It explores
    "Acetylcholinesterase",
      the development of multi-target-directed ligands, novel drug therapies, and
    "Butyrylcholinesterase",
      the implications for cognitive deficits. The research also delves into the structure,
    "Alzheimer's Disease",
      function, and regulation of cholinesterases, as well as their potential roles
    "Neurodegenerative Diseases",
      in neuroprotection and neurorestoration.
    "Multi-Target-Directed Ligands",
     display_name: Cholinesterase Inhibitors in Neurodegenerative Diseases
    "Pharmacology",
     domain:
     "Toxicology",
      display_name: Health Sciences
    "Drug Development",
      id: https://openalex.org/domains/4
    "Cognitive Deficits"
     field:
  ],
      display_name: Medicine
  "ids": {
      id: https://openalex.org/fields/27
    "openalex": "https://openalex.org/T12023",
     id: https://openalex.org/T12023
     "wikipedia": "https://en.wikipedia.org/wiki/Cholinesterase_inhibitor"
     ids:
  },
      openalex: https://openalex.org/T12023
  "subfield": {
      wikipedia: https://en.wikipedia.org/wiki/Cholinesterase_inhibitor
     "id": "https://openalex.org/subfields/2736",
     keywords:
     "display_name": "Pharmacology"
    - Cholinesterase Inhibitors
  },
    - Acetylcholinesterase
  "field": {
     - Butyrylcholinesterase
    "id": "https://openalex.org/fields/27",
    - Alzheimer's Disease
    "display_name": "Medicine"
    - Neurodegenerative Diseases
  },
    - Multi-Target-Directed Ligands
  "domain": {
    - Pharmacology
    "id": "https://openalex.org/domains/4",
    - Toxicology
     "display_name": "Health Sciences"
    - Drug Development
  },
    - Cognitive Deficits
  "siblings": [
    siblings:
     {
    - display_name: Apelin Signaling and Physiology
      "id": "https://openalex.org/T13505",
       id: https://openalex.org/T13505
      "display_name": "Apelin Signaling and Physiology"
    - display_name: Biosynthesis and Pharmacological Activities of Medicinal Natural
    },
        Products
    {
       id: https://openalex.org/T13921
       "id": "https://openalex.org/T13921",
    - display_name: Chromones and Flavonoids in Medicinal Chemistry
      "display_name": "Biosynthesis and Pharmacological Activities of Medicinal Natural Products"
       id: https://openalex.org/T13023
    },
    - display_name: Cyclooxygenase-2 Inhibitors in Inflammation and Cancer
    {
       id: https://openalex.org/T10678
       "id": "https://openalex.org/T13023",
    - display_name: Effects of Caffeine on Human Health
      "display_name": "Chromones and Flavonoids in Medicinal Chemistry"
       id: https://openalex.org/T11264
    },
    - display_name: Endocannabinoid System and Its Effects on Health
    {
       id: https://openalex.org/T10414
       "id": "https://openalex.org/T10678",
    - display_name: Global Burden of Chronic Pain
      "display_name": "Cyclooxygenase-2 Inhibitors in Inflammation and Cancer"
       id: https://openalex.org/T10084
    },
    - display_name: Halotherapy and its Health Implications
    {
       id: https://openalex.org/T13809
       "id": "https://openalex.org/T11264",
    - display_name: Hypersensitivity Reactions to Drugs and Medications
      "display_name": "Effects of Caffeine on Human Health"
       id: https://openalex.org/T11117
    },
    - display_name: Medicinal Leeches in Scientific Research
    {
       id: https://openalex.org/T13767
       "id": "https://openalex.org/T10414",
    - display_name: 'Medicinal Mushrooms: Antitumor and Immunomodulating Properties'
      "display_name": "Endocannabinoid System and Its Effects on Health"
       id: https://openalex.org/T11085
    },
    - display_name: Medicinal Orchids in Traditional Medicine and Pharmacology
    {
       id: https://openalex.org/T13130
       "id": "https://openalex.org/T10084",
    - display_name: Molecular Mechanisms of Depression Treatment Strategies
      "display_name": "Global Burden of Chronic Pain"
       id: https://openalex.org/T11071
    },
    - display_name: Natural Products as Sources of New Drugs
    {
       id: https://openalex.org/T10252
       "id": "https://openalex.org/T13809",
    - display_name: Pharmacokinetics of Antibiotics in Critically Ill Patients
      "display_name": "Halotherapy and its Health Implications"
       id: https://openalex.org/T11036
    },
    - display_name: Pharmacological Management of Obesity
    {
       id: https://openalex.org/T12539
       "id": "https://openalex.org/T11117",
    - display_name: Scientific and Medical Aspects of Ozone Therapy
      "display_name": "Hypersensitivity Reactions to Drugs and Medications"
       id: https://openalex.org/T13365
    },
    - display_name: Therapeutic Applications of Bee Venom Therapy
    {
       id: https://openalex.org/T14028
       "id": "https://openalex.org/T13767",
    - display_name: Therapeutic Potential of Berberine Alkaloids
      "display_name": "Medicinal Leeches in Scientific Research"
       id: https://openalex.org/T12059
    },
    - display_name: Therapeutic Potential of Boswellic Acids and Related Compounds
    {
       id: https://openalex.org/T13335
       "id": "https://openalex.org/T11085",
    - display_name: Therapeutic Potential of Flavonoids in Medicine
      "display_name": "Medicinal Mushrooms: Antitumor and Immunomodulating Properties"
      id: https://openalex.org/T12582
    },
    subfield:
    {
      display_name: Pharmacology
       "id": "https://openalex.org/T13130",
      id: https://openalex.org/subfields/2736
      "display_name": "Medicinal Orchids in Traditional Medicine and Pharmacology"
    updated_date: '2024-05-20T05:09:04.016951'
    },
    works_count: 45263
    {
       "id": "https://openalex.org/T11071",
      "display_name": "Molecular Mechanisms of Depression Treatment Strategies"
    },
    {
       "id": "https://openalex.org/T10252",
      "display_name": "Natural Products as Sources of New Drugs"
    },
    {
       "id": "https://openalex.org/T11036",
      "display_name": "Pharmacokinetics of Antibiotics in Critically Ill Patients"
    },
    {
       "id": "https://openalex.org/T12539",
      "display_name": "Pharmacological Management of Obesity"
    },
    {
       "id": "https://openalex.org/T13365",
      "display_name": "Scientific and Medical Aspects of Ozone Therapy"
    },
    {
       "id": "https://openalex.org/T14028",
      "display_name": "Therapeutic Applications of Bee Venom Therapy"
    },
    {
       "id": "https://openalex.org/T12059",
      "display_name": "Therapeutic Potential of Berberine Alkaloids"
    },
    {
       "id": "https://openalex.org/T13335",
      "display_name": "Therapeutic Potential of Boswellic Acids and Related Compounds"
    },
    {
       "id": "https://openalex.org/T12582",
      "display_name": "Therapeutic Potential of Flavonoids in Medicine"
    }
  ],
  "works_count": 45649,
  "cited_by_count": 946380,
  "updated_date": "2024-08-26T06:08:55.929962",
  "created_date": "2024-01-23"
}

Revision as of 13:23, 30 August 2024

{

 "id": "https://openalex.org/T12023",
 "display_name": "Cholinesterase Inhibitors in Neurodegenerative Diseases",
 "description": "This cluster of papers focuses on the pharmacology and toxicology of cholinesterase inhibitors, particularly acetylcholinesterase and butyrylcholinesterase, in the context of neurodegenerative diseases such as Alzheimer's. It explores the development of multi-target-directed ligands, novel drug therapies, and the implications for cognitive deficits. The research also delves into the structure, function, and regulation of cholinesterases, as well as their potential roles in neuroprotection and neurorestoration.",
 "keywords": [
   "Cholinesterase Inhibitors",
   "Acetylcholinesterase",
   "Butyrylcholinesterase",
   "Alzheimer's Disease",
   "Neurodegenerative Diseases",
   "Multi-Target-Directed Ligands",
   "Pharmacology",
   "Toxicology",
   "Drug Development",
   "Cognitive Deficits"
 ],
 "ids": {
   "openalex": "https://openalex.org/T12023",
   "wikipedia": "https://en.wikipedia.org/wiki/Cholinesterase_inhibitor"
 },
 "subfield": {
   "id": "https://openalex.org/subfields/2736",
   "display_name": "Pharmacology"
 },
 "field": {
   "id": "https://openalex.org/fields/27",
   "display_name": "Medicine"
 },
 "domain": {
   "id": "https://openalex.org/domains/4",
   "display_name": "Health Sciences"
 },
 "siblings": [
   {
     "id": "https://openalex.org/T13505",
     "display_name": "Apelin Signaling and Physiology"
   },
   {
     "id": "https://openalex.org/T13921",
     "display_name": "Biosynthesis and Pharmacological Activities of Medicinal Natural Products"
   },
   {
     "id": "https://openalex.org/T13023",
     "display_name": "Chromones and Flavonoids in Medicinal Chemistry"
   },
   {
     "id": "https://openalex.org/T10678",
     "display_name": "Cyclooxygenase-2 Inhibitors in Inflammation and Cancer"
   },
   {
     "id": "https://openalex.org/T11264",
     "display_name": "Effects of Caffeine on Human Health"
   },
   {
     "id": "https://openalex.org/T10414",
     "display_name": "Endocannabinoid System and Its Effects on Health"
   },
   {
     "id": "https://openalex.org/T10084",
     "display_name": "Global Burden of Chronic Pain"
   },
   {
     "id": "https://openalex.org/T13809",
     "display_name": "Halotherapy and its Health Implications"
   },
   {
     "id": "https://openalex.org/T11117",
     "display_name": "Hypersensitivity Reactions to Drugs and Medications"
   },
   {
     "id": "https://openalex.org/T13767",
     "display_name": "Medicinal Leeches in Scientific Research"
   },
   {
     "id": "https://openalex.org/T11085",
     "display_name": "Medicinal Mushrooms: Antitumor and Immunomodulating Properties"
   },
   {
     "id": "https://openalex.org/T13130",
     "display_name": "Medicinal Orchids in Traditional Medicine and Pharmacology"
   },
   {
     "id": "https://openalex.org/T11071",
     "display_name": "Molecular Mechanisms of Depression Treatment Strategies"
   },
   {
     "id": "https://openalex.org/T10252",
     "display_name": "Natural Products as Sources of New Drugs"
   },
   {
     "id": "https://openalex.org/T11036",
     "display_name": "Pharmacokinetics of Antibiotics in Critically Ill Patients"
   },
   {
     "id": "https://openalex.org/T12539",
     "display_name": "Pharmacological Management of Obesity"
   },
   {
     "id": "https://openalex.org/T13365",
     "display_name": "Scientific and Medical Aspects of Ozone Therapy"
   },
   {
     "id": "https://openalex.org/T14028",
     "display_name": "Therapeutic Applications of Bee Venom Therapy"
   },
   {
     "id": "https://openalex.org/T12059",
     "display_name": "Therapeutic Potential of Berberine Alkaloids"
   },
   {
     "id": "https://openalex.org/T13335",
     "display_name": "Therapeutic Potential of Boswellic Acids and Related Compounds"
   },
   {
     "id": "https://openalex.org/T12582",
     "display_name": "Therapeutic Potential of Flavonoids in Medicine"
   }
 ],
 "works_count": 45649,
 "cited_by_count": 946380,
 "updated_date": "2024-08-26T06:08:55.929962",
 "created_date": "2024-01-23"

}